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Inicio Medicina Clínica Prevalencia e incidencia de la infección por el virus de la hepatitis A en paci...
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Vol. 115. Issue 7.
Pages 254-255 (January 2000)
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Vol. 115. Issue 7.
Pages 254-255 (January 2000)
Prevalencia e incidencia de la infección por el virus de la hepatitis A en pacientes con hepatitis crónica B y C
Prevalence and incidence of hepatitis A in patients with hepatitis B and C
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Gemma Olivé, Maria Buti*, Juan Ignacio Esteban, Montserrat Cotrina, Rafael Esteban, Jaume Guardia
Servicio de Hepatología. Hospital General Universitario Vall d'Hebron. Barcelona
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Fundamento

Los pacientes con hepatitis crónica tienen un mayor riesgo de desarrollar una hepatitis fulminante al sobreinfec-tarse por el virus de la hepatitis A (VHA).

Pacientes y métodos

Se han determinado los anticuerpos IgG anti-VHA en 353 hepatitis crónicas B o C, y los IgM en las hepatitis agudas.

Resultados

La prevalencia de anticuerpos IgG anti-VHA fue del 81% en la hepatitis crónica C y del 77% en la hepatitis B, rela-cionándose con la edad. No se detectó ninguna hepatitis aguda A.

Conclusiones

La prevalencia del VHA es elevada en las hepatitis crónicas virales mientras que la incidencia es baja. La va-cunación antihepatitis A deberra realizarse con cribado previo.

Palabras clave:
Hepatitis A
Hepatitis B
Hepatitis C
Hepatitis crónica
Background

Patients with chronic hepatitis are in risk to acquire a fulminant hepatitis associated with hepatitis A virus superinfection.

Patients and methods

Antibodies against hepatitis A were study in serum from 353 patients with chronic hepatitis B or C.

Results

The prevalence of IgG-HAV antibodies was 81% in chronic hepatitis C patients, and 77% in chronic hepatitis B pa-tients. The presence of anti-HAV antibodies was related to the patients' age. None case of acute hepatitis A in chronic hepatitis patients was detected.

Conclusions

The prevalence of anti-HAV antibodies is high in patients with chronic viral hepatitis but the incidence of the disease is low. Hepatitis A vaccination should do with previously screening.

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