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After three weeks of respiratory symptoms, skin lesions developed without any other accompanying symptoms.</p><p id="par0020" class="elsevierStylePara elsevierViewall">Both patients showed confluent erythematous-violaceous papular plaques, some targetoid, a diagnostic key to EEM (<a class="elsevierStyleCrossRefs" href="#fig0005">Figs. 1 and 2</a>). These symptoms were resolved with a prednisone regimen of 0.5 mg/kg/day.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0025" class="elsevierStylePara elsevierViewall">Various cutaneous manifestations associated with SARS-CoV-2 infection have been described. In addition, the numerous drugs used for its treatment make the occurrence of potentially serious toxicoderma expected, requiring correct aetiology and specific management, such as the discontinuation of the drug involved.</p><p id="par0030" class="elsevierStylePara elsevierViewall">We report two cases of presumably drug-related EEM, given its late onset and good response to corticosteroid therapy. However, these dermatoses could represent a SARS-CoV-2-induced skin involvement, as this is a recent, little-known disease.</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Funding</span><p id="par0035" class="elsevierStylePara elsevierViewall">The authors declare that they have not received funding to carry out this study</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Conflict of interests</span><p id="par0040" class="elsevierStylePara elsevierViewall">The authors declare no conflict of interest.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:2 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Funding" ] 1 => array:2 [ "identificador" => "sec0010" "titulo" => "Conflict of interests" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Sánchez-Velázquez A, Falkenhain D, Rivera Díaz R. Eritema multiforme en contexto de infección por SARS-Coronavirus-2. Med Clin (Barc). 2020;155:141.</p>" ] ] "multimedia" => array:2 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 564 "Ancho" => 750 "Tamanyo" => 107059 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Fig. " "rol" => "short" ] ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1123 "Ancho" => 750 "Tamanyo" => 158292 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0010" "detalle" => "Fig. " "rol" => "short" ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/23870206/0000015500000003/v1_202008150733/S2387020620302874/v1_202008150733/en/main.assets" "Apartado" => array:4 [ "identificador" => "51820" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Images in medicine" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/23870206/0000015500000003/v1_202008150733/S2387020620302874/v1_202008150733/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020620302874?idApp=UINPBA00004N" ]
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