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Original article
Evaluation of telephone assessment in stroke and TIA recurrence
Evaluación de la revisión telefónica en la recurrencia de ictus y AIT
F. Monichea,
Corresponding author
pmoniche@gmail.com

Corresponding author.
, F.J. De La Torre Lavianaa, A. Palomino Garcíaa, A. Cayuela Domínguezb, E. Vigilb, M.D. Jiméneza
a Unidad de Ictus, Servicio de Neurología, Hospital Universitario Virgen del Rocío, Sevilla, Spain
b Servicio de Documentación Clínica, Hospital Universitario Virgen del Rocío, Sevilla, Spain
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    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">Recurrence after a stroke is a key element in the study of cerebrovascular disease and provides information on the effectiveness of secondary prevention measures adopted after the event&#46; Factors that influence recurrence include advanced age&#44; diabetes mellitus and hemorrhagic stroke&#44; with the estimated risk of recurrent stroke being close to 22&#46;5&#37; in the first 5 years&#44;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> although it is more common in the first 6 months &#40;8&#37;&#8211;10&#37;&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">Given the importance and frequency of stroke recurrence&#44; it is important to record it systematically&#46; However&#44; hospital stroke records often assess recurrence retrospectively or based on readmission of a patient at the same centre&#46; This is due to the fact that conducting reviews through direct contact months after a stroke is not always feasible and may determine a selection of the patients reviewed&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">Reviews conducted by telephone through structured interviews can simplify the long-term evaluation of patients after stroke and potentially reduce its costs&#46; Although reviews by telephone have been used in the assessment of functional status and even cognitive status of patients&#44;<a class="elsevierStyleCrossRefs" href="#bib0015"><span class="elsevierStyleSup">3&#44;4</span></a> there are few prospective studies that examine the telephonic review as a method of evaluating recurrence after a stroke&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">The aim of this study was to determine the feasibility of telephonic review of patients after a stroke&#44; in the context of hospital stroke records&#44; assessing the detection of recurrent stroke or transient ischemic attacks &#40;TIAs&#41; and functional status at 6 months from the event&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Material and methods</span><p id="par0025" class="elsevierStylePara elsevierViewall">We performed a prospective study&#44; recording 380 consecutive cases of ischemic stroke&#44; hemorrhagic stroke or TIA treated at the emergency department of a tertiary hospital&#46; We evaluated baseline demographic data such as gender&#44; age and vascular risk factors&#44; as well as any treatments followed prior to the stroke&#46; The initial severity of the event was assessed using the Canadian scale &#40;Canadian Stroke Scale&#41; upon arrival of the patient at the emergency department&#59; in those cases in which an evaluation according to this scale was not available&#44; we estimated according to the initial neurological examination&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">For the diagnosis of TIA&#44; we used the criteria of the World Health Organisation &#40;WHO&#41;&#44; which define it as the presence of focal neurological symptoms of vascular origin and sudden onset&#44; and with a duration of less than 24<span class="elsevierStyleHsp" style=""></span>h&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">Patients were reviewed by a neurologist experienced in stroke at 6 months after the event&#46; Patients were divided into 2 groups&#44; personal review and telephonic review&#46; Consecutively&#44; the first 248 patients included were reviewed using a structured interview by telephone and the following 132 patients were reviewed in person&#46; In both cases there were recurrences of both TIA and new established&#44; ischemic or hemorrhagic events&#46; These were assessed by patient interview as well as by review of emergency admissions and hospital admissions recorded during that period&#46; Furthermore&#44; we evaluated treatment with antithrombotic agents and for the control of vascular risk factors at the time of the review and the functional status of the patient using the modified Rankin scale and Barthel index&#46; In those cases where it was not possible to conduct a review at the hospital due to distance or disability&#44; it was conducted by telephone&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">Subsequently&#44; we compared the baseline characteristics of patients according to the type of review and the data corresponding to recurrences&#44; treatment followed and functional status of patients at 6 months&#46; The qualitative variables according to study groups &#40;telephone or physical review&#41; were analysed using the chi-square test or Fisher&#39;s exact test when necessary and were expressed as absolute and relative frequencies&#46; Quantitative variables were analysed using the Mann&#8211;Whitney <span class="elsevierStyleItalic">U</span> test&#44; since they did not follow a normal distribution&#44; and were expressed as medians &#40;interquartile range&#41;&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">This study was approved by the local ethics committee and patients signed an informed consent form prior to inclusion&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Results</span><p id="par0050" class="elsevierStylePara elsevierViewall">Of the total of 380 registered patients&#44; 248 &#40;65&#46;3&#37;&#41; were reviewed by telephone and 132 &#40;34&#46;7&#37;&#41; were assessed in person during hospital consultation&#46; A total of 13 patients who had been assigned to personal review could not attend due to disability or distance and were reviewed by telephone&#46; When comparing the 2 types of reviews&#44; we did not detect significant differences by age group&#46; We found a high percentage of patients above 80 years of age in both groups &#40;31&#37; of those reviewed by telephone vs 28&#37; reviewed in person&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;46&#41;&#46; As for gender&#44; no differences were found between both groups&#44; with 49&#46;2&#37; of patients being females &#40;<a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0055" class="elsevierStylePara elsevierViewall">The types of initial vascular events were distributed similarly amongst both groups &#40;<a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a>&#41;&#44; with no significant differences being found&#46; Ischemic stroke accounted for 58&#37; &#40;59&#37; in telephonic reviews and 56&#37; in personal reviews&#41;&#44; TIA for 36&#37; &#40;36&#37; in both groups&#41; and hemorrhagic stroke for 5&#46;8&#37; &#40;5&#37; and 8&#37; respectively&#41;&#46; The severity of the initial stroke on arrival at the emergency service&#44; as assessed through the Canadian Stroke Scale&#44; was also comparable between patients from both types of review &#40;median<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>9 &#91;7&#46;5&#8211;10&#93; of telephone reviews vs 9 &#91;8&#46;0&#8211;10&#93; of personal reviews&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;31&#41;&#46;</p><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><p id="par0060" class="elsevierStylePara elsevierViewall">An evaluation of the baseline presence of vascular risk factors in the patients reviewed in person and by telephone revealed no significant differences between both groups &#40;<a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>&#41;&#46; Up to 75&#37; of patients presented a history of hypertension &#40;75&#46;8&#37; reviewed by telephone vs 74&#46;2&#37; reviewed in person&#41;&#44; 38&#37; were diabetic &#40;37&#37; vs 39&#37;&#41; and 27&#37; in both groups suffered dyslipidemia&#46; Up to 14&#46;5&#37; were active smokers and 12&#46;1&#37; were former smokers&#46; Only 11&#46;3&#37; presented known peripheral arterial disease and 21&#37; presented atrial fibrillation&#46; Up to one third of patients in both groups had suffered a previous episode of stroke or TIA &#40;32&#37; reviewed by telephone vs 34&#37; reviewed in person&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;66&#41;&#46; After the initial event&#44; 92&#46;6&#37; of patients were discharged from the hospital with antithrombotic therapy&#44; with no differences between both groups&#46; The majority &#40;73&#46;2&#37;&#41; were treated with antihypertensive agents&#44; 35&#46;3&#37; were treated for diabetes and 31&#46;8&#37; were treated with statins&#44; with no significant differences between both groups&#46;</p><p id="par0065" class="elsevierStylePara elsevierViewall">At 6 months&#44; 10&#46;5&#37; of the total &#40;40 patients&#41; suffered recurrence of a cerebrovascular event &#40;<a class="elsevierStyleCrossRef" href="#tbl0015">Table 3</a>&#41;&#46; We detected a trend towards higher detection rates of recurrent events in the group of patients reviewed in person than in those reviewed by telephone &#40;15&#46;9&#37; vs 9&#46;2&#37;&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;07&#41;&#46; When assessing the type of recurrence detected&#44; 19 patients of the total &#40;5&#37;&#41; presented a recurrent ischemic stroke&#44; with a similar frequency in both groups &#40;4&#46;4&#37; in those reviewed by telephone compared to 6&#46;1&#37; in those reviewed in person&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;5&#41;&#46; However&#44; when evaluating the cases of TIA detected&#44; we noted a significant increase in diagnoses among patients reviewed in person compared to those reviewed by telephone &#40;9&#46;1&#37; vs 4&#46;0&#37;&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;04&#41;&#46; There were no recurrences of hemorrhagic stroke at 6 months&#46;</p><elsevierMultimedia ident="tbl0015"></elsevierMultimedia><p id="par0070" class="elsevierStylePara elsevierViewall">Regarding the treatment performed at the time of the review&#44; 90&#37; of patients continued with antithrombotic medication&#44; with this percentage being slightly higher among patients reviewed in person &#40;89&#37; in patients reviewed by telephone vs 94&#37; in patients reviewed in person&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;06&#41;&#46; Of these&#44; 18&#37; followed oral anticoagulation &#40;18&#46;8&#37; vs 17&#46;4&#37;&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;58&#41;&#46; No significant differences were found between both groups regarding antihypertensive&#44; antidiabetic or hypolipidemic treatment&#46; Finally&#44; we evaluated the functional scales and found a greater degree of disability according to the modified Rankin scale and Barthel index in the group of patients reviewed by telephone compared to those reviewed in person &#40;median&#58; 2&#46;0 vs 1&#46;0&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;01&#59; 90 vs 100&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;01&#44; respectively&#41; &#40;<a class="elsevierStyleCrossRef" href="#tbl0020">Table 4</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0020"></elsevierMultimedia></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Discussion</span><p id="par0075" class="elsevierStylePara elsevierViewall">Stroke is a major cause of mortality in the world and&#44; in Spain&#44; as in other countries&#44; it is a health priority&#46; Although the mortality rate has steadily decreased in recent years&#44; stroke causes chronic disability in many patients and represents a major social and healthcare cost&#46; For this reason&#44; it is important to keep records of stroke patients at those centres offering care for this pathology&#44; to assess short-&#44; medium- and long-term morbidity and mortality in clinical practice&#44; as well as recurrences&#46; Although the possibility of stroke recurrence is maintained in the long term&#44; it is much more common within the first 6&#8211;12 months after the initial event&#44; reaching figures of up to 9&#37; and 13&#37;&#8211;14&#37;&#44; respectively&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> This higher initial recurrence is particularly relevant in TIA&#44; since rates of occurrence of stroke after TIA of nearly 10&#37; in the first 90 days have been described&#46;<a class="elsevierStyleCrossRefs" href="#bib0025"><span class="elsevierStyleSup">5&#44;6</span></a> Therefore&#44; stroke records typically include reviews at 6 months or 1 year after the initial event&#44; in order to establish the functional status of the patient and also to detect new vascular events&#46; However&#44; given the high incidence of cerebrovascular disease&#44; direct contact and review of all patients in person is not always feasible and represents a challenge for the maintenance of records&#46;</p><p id="par0080" class="elsevierStylePara elsevierViewall">Telephone assessment of stroke patients has frequently been used in clinical trials and stroke registries&#44;<a class="elsevierStyleCrossRefs" href="#bib0035"><span class="elsevierStyleSup">7&#8211;9</span></a> as it simplifies the design of studies&#44; reduces costs and potentially avoids investigator bias derived from the knowledge of clinical data&#44; especially in the assessment of functional scales&#46; There are several studies comparing the validity of the assessment of functional scales such as the Barthel index and the modified Rankin scale through reviews conducted by telephone compared to physical or in-person examination of stroke patients&#46;<a class="elsevierStyleCrossRefs" href="#bib0050"><span class="elsevierStyleSup">10&#44;11</span></a> Newcommon et al&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">10</span></a> found excellent agreement between observers in the assessment of the Rankin scale in reviews conducted in person &#40;<span class="elsevierStyleItalic">K</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;72&#41;&#44; but with much greater variability when the review was conducted by telephone &#40;<span class="elsevierStyleItalic">K</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;3&#41;&#46; However&#44; the use of a structured interview for the application of functional scales manages to reduce interobserver variability and improves the quality of the studies&#46;<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">12</span></a> It has recently been proven that the use of structured interviews is also useful during telephone reviews&#44; optimising agreement between observers&#46;<a class="elsevierStyleCrossRef" href="#bib0065"><span class="elsevierStyleSup">13</span></a></p><p id="par0085" class="elsevierStylePara elsevierViewall">Telephone interviews have been used not only to assess the functional patient status after stroke&#44; but also to study the presence of cognitive impairment&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> However&#44; there are few studies in the literature evaluating the use of telephonic reviews of the clinical outcome of stroke and the onset of recurrences&#46; Using a telephonic survey conducted by an experienced researcher&#44; Meschia et al&#46;<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">14</span></a> found high reliability in the detection of patients without stroke or TIA&#44; but with less specificity in the diagnosis of new strokes or TIAs compared to those reviewed in person&#46;</p><p id="par0090" class="elsevierStylePara elsevierViewall">In the present study&#44; after reviewing 380 patients at 6 months after a cerebrovascular event&#44; we detected 10&#46;5&#37; of recurrences of new strokes or TIAs&#46; Despite studying 2 samples with equal baseline characteristics&#44; when comparing the 2 types of reviews&#44; detection of recurrences was more frequent in personal reviews than in telephonic reviews&#46; Although the rate of new ischemic strokes was similar in both groups and equivalent to that described previously in the literature&#44;<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1&#44;2&#44;15</span></a> TIAs were diagnosed significantly more often during direct contact with patients &#40;9&#46;1&#37; vs 4&#46;0&#37;&#41;&#46; This may be because telephonic interviews are conducted in a shorter time than personal interviews&#44; usually in a few minutes&#44;<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">14</span></a> so the detection of minor events such as TIA can be difficult&#46; In addition&#44; while telephonic interviews are usually conducted with a single person &#40;the patient or a relative&#41;&#44; personal reviews are conducted more in depth with both patients and companions&#44; which facilitates the detection of any type of event&#46; This is especially relevant when considering the high frequency of patients with neurological deficit of less than 24<span class="elsevierStyleHsp" style=""></span>h duration diagnosed with TIA&#44; who present an ischemic lesion identified by neuroimaging &#40;up to 50&#37; of patients&#41;&#44;<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">16</span></a> and which are actually established ischemic strokes&#46; This has even led to a recent change in the traditional definition of TIA&#46;<a class="elsevierStyleCrossRef" href="#bib0085"><span class="elsevierStyleSup">17</span></a></p><p id="par0095" class="elsevierStylePara elsevierViewall">Despite the difference in the recurrence of new events&#44; the treatments for both groups at the time of the review were very similar&#46; Neither antithrombotic therapy nor that of vascular risk factors differed significantly in both samples&#46;</p><p id="par0100" class="elsevierStylePara elsevierViewall">The evaluation of functional scales showed a greater dependence of patients reviewed by telephone&#46; This is probably justified by the fact that patients who were interviewed by telephone were those for whom it was not possible to attend a physical examination in the hospital due to their functional status&#46; This could represent a limitation&#44; as a greater number of events might be expected in telephonic reviews&#46; Nevertheless&#44; this study detected more events in the group reviewed in person&#44; which does not justify a greater disability in the group reviewed by telephone&#46; On the other hand&#44; this is one of the advantages of telephonic reviews since&#44; while making it possible to maintain stroke records and evaluation of new events&#44; they avoid movement of patients that would otherwise be very difficult&#46;</p><p id="par0105" class="elsevierStylePara elsevierViewall">Consequently&#44; the telephonic review of stroke patients is a viable method that facilitates the completion of stroke records and the assessment of treatments and recurrences&#46; However&#44; detection of new transient events or TIAs is probably underestimated in this type of review&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Conflict of interests</span><p id="par0110" class="elsevierStylePara elsevierViewall">The authors have no conflicts of interest to declare&#46;</p></span></span>"
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          "identificador" => "xres169694"
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            0 => "Resumen"
            1 => "Introducci&#243;n"
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            3 => "Resultados"
            4 => "Conclusiones"
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        5 => array:2 [
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          "titulo" => "Material and methods"
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        6 => array:2 [
          "identificador" => "sec0015"
          "titulo" => "Results"
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        7 => array:2 [
          "identificador" => "sec0020"
          "titulo" => "Discussion"
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        8 => array:2 [
          "identificador" => "sec0025"
          "titulo" => "Conflict of interests"
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        9 => array:1 [
          "titulo" => "References"
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    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2010-11-28"
    "fechaAceptado" => "2011-03-06"
    "PalabrasClave" => array:2 [
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        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec157775"
          "palabras" => array:7 [
            0 => "Stroke outcome"
            1 => "Telephone interview"
            2 => "Cerebral ischaemia"
            3 => "Transient"
            4 => "Stroke registry"
            5 => "Disability evaluation"
            6 => "Stroke recurrence"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec157774"
          "palabras" => array:6 [
            0 => "Evoluci&#243;n del ictus"
            1 => "Entrevista telef&#243;nica"
            2 => "Accidente isqu&#233;mico transitorio"
            3 => "Registro de ictus"
            4 => "Evaluaci&#243;n de discapacidad"
            5 => "Recurrencia de ictus"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<span class="elsevierStyleSectionTitle">Introduction</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Stroke recurrence is an important issue in stroke registries&#44; but direct patient contact months after stroke is not always feasible&#46; Telephone assessment is often used to evaluate long term stroke outcome&#44; treatments and recurrences&#46; Our aim is to evaluate telephone interview in a stroke registry&#46;</p> <span class="elsevierStyleSectionTitle">Material and methods</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Three hundred and eighty patients with a stroke or TIA were prospectively registered&#44; evaluating baseline characteristics and type of event&#46; At 6 months&#44; 248 patients were reviewed by structured telephone interview and 132 were reviewed by direct contact&#46; We analysed stroke outcome and disability&#44; treatments and stroke or TIA recurrences&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">There were no differences in baseline characteristics and type or severity of the index event&#46; At 6 months&#44; treatments were similar between both groups and 10&#46;5&#37; &#40;40 patients&#41; had a recurrent event&#46; There were no differences in recurrent ischemic strokes &#40;6&#46;1&#37; in direct contact vs 4&#46;4&#37; telephone&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;49&#41;&#44; but we detected a higher number of TIA in direct examination compared to phone interview &#40;9&#46;1&#37; vs 4&#46;0&#37;&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;04&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Telephone assessment of stroke patients is reliable and facilitates stroke registries in detecting long-term treatments and stroke recurrences&#46; However&#44; it is probable that new transient events or TIA are under-estimated&#46;</p>"
      ]
      "es" => array:2 [
        "titulo" => "Resumen"
        "resumen" => "<span class="elsevierStyleSectionTitle">Introducci&#243;n</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">La recurrencia de ictus o AIT es un aspecto clave en la mayor&#237;a de los registros de ictus&#44; pero la revisi&#243;n presencial de todos los pacientes no siempre es viable&#46; Con frecuencia&#44; la revisi&#243;n telef&#243;nica es utilizada para evaluar las recurrencias&#44; la situaci&#243;n funcional y los tratamientos a largo plazo&#46; El objetivo es evaluar la revisi&#243;n telef&#243;nica en un registro de ictus&#46;</p> <span class="elsevierStyleSectionTitle">Material y m&#233;todos</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Se registraron prospectivamente 380 pacientes con ictus o AIT valorando las caracter&#237;sticas basales y tipo de evento&#46; Posteriormente&#44; fueron evaluados a los 6 meses tras el evento inicial&#46; Doscientos cuarenta y ocho pacientes fueron revisados telef&#243;nicamente mediante una entrevista estructurada y 132 fueron revisados f&#237;sicamente en consulta&#46; Se compararon ambos grupos analizando las diferencias detectadas en las escalas funcionales&#44; tratamientos y recurrencias &#40;AIT o ictus&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">No hubo diferencias en las caracter&#237;sticas basales de ambos grupos&#44; ni en el tipo de evento o gravedad al inicio&#46; A los 6 meses&#44; los tratamientos realizados fueron similares en ambos grupos&#44; presentando un 10&#44;5&#37; &#40;40 pacientes&#41; recurrencia de ictus o AIT&#46; No hubo diferencias significativas en la tasa de nuevos ictus isqu&#233;micos &#40;6&#44;1&#37; revisi&#243;n f&#237;sica vs 4&#44;4&#37; telef&#243;nica&#44; p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;49&#41;&#44; pero se detect&#243; un mayor n&#250;mero de AIT en la revisi&#243;n f&#237;sica frente a la telef&#243;nica &#40;9&#44;1&#37; vs 4&#44;0&#37;&#44; p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;04&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">La revisi&#243;n telef&#243;nica de los pacientes con ictus es viable y facilita la realizaci&#243;n de registros de ictus&#44; permitiendo una adecuada identificaci&#243;n de los tratamientos y recurrencias de ictus&#46; Sin embargo&#44; es probable que los nuevos eventos transitorios o AIT est&#233;n infraestimados&#46;</p>"
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        "nota" => "<p class="elsevierStyleNotepara">Please cite this article as&#58; Moniche F&#44; et al&#46; Evaluaci&#243;n de la revisi&#243;n telef&#243;nica en la recurrencia de ictus y AIT&#46; Neurolog&#237;a&#46; 2011&#59;27&#58;97&#8211;102&#46;</p>"
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                  \t\t\t\t" style="border-bottom: 2px solid black">Review by telephone &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>248&#41; No&#46; &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">90 &#40;36&#46;4&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="char" valign="\n
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                  \t\t\t\t">42 &#40;31&#46;8&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">58 &#40;43&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Hypertension&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="char" valign="\n
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                  \t\t\t\t">188 &#40;758&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
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                  \t\t\t\t">98 &#40;74&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Diabetes&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="char" valign="\n
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                  \t\t\t\t">92 &#40;37&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
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                  \t\t\t\t">52 &#40;39&#46;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;66&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Dyslipidemia&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">66 &#40;26&#46;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
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                  \t\t\t\t">35 &#40;26&#46;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
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                  \t\t\t\t">&#46;98&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Active smokers&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
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                  \t\t\t\t">35 &#40;14&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
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                  \t\t\t\t">20 &#40;15&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
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                  \t\t\t\t">&#46;89&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Atrial fibrillation&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">50 &#40;20&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">29 &#40;22&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;68&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Peripheral arteriopathy&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">28 &#40;11&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
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                  \t\t\t\t">15 &#40;11&#46;4&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;98&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>TIA or prior stroke&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">79 &#40;31&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">45 &#40;34&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;66&nbsp;\t\t\t\t\t\t\n
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                  """
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          "leyenda" => "<p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">IR&#58; interquartile range&#46;</p>"
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                  \t\t\t\t" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t" style="border-bottom: 2px solid black">Review by telephone &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>248&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t" style="border-bottom: 2px solid black">Review in person &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>132&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">Type of initial event &#91;No&#46; &#40;&#37;&#41;&#93;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
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                  \t\t\t\t">&#46;29&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">TIA&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">89 &#40;35&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">47 &#40;35&#46;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">Ischemic stroke&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttop\n
                  \t\t\t\t">74 &#40;56&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Hemorrhagic stroke&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">11 &#40;4&#46;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">11 &#40;8&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Canadian neurological scale &#40;admission&#41; &#40;median &#91;IR&#93;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">9&#46;0 &#40;7&#46;5&#8211;10&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">9&#46;0 &#40;8&#46;0&#8211;10&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;31&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
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          "en" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Type of initial event&#46;</p>"
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                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><td class="td" title="\n
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                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">Review by telephone &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>248&#41; No&#46; &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">Review in person &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>132&#41; No&#46; &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black"><span class="elsevierStyleItalic">P</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Total recurrences&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">21 &#40;9&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">19 &#40;15&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;07&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">TIA&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">10 &#40;4&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">12 &#40;9&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;04&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Ischemic stroke&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">11 &#40;4&#46;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8 &#40;6&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;49&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Hemorrhagic stroke&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#8211;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
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        "tabla" => array:2 [
          "leyenda" => "<p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">IR&#58; interquartile range&#46;</p>"
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            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">Review by telephone &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>248&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black">Review in person &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>132&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" style="border-bottom: 2px solid black"><span class="elsevierStyleItalic">P</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Treatment prescribed &#91;No&#46; &#40;&#37;&#41;&#93;</span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Antithrombotic&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">220 &#40;88&#46;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">125 &#40;94&#46;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;55&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Antihypertensive&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">176 &#40;71&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">98 &#40;74&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;49&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Antidiabetic&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">81 &#40;32&#46;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">44 &#40;33&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;89&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Hypolipidemic&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">74 &#40;29&#46;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">45 &#40;34&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;39&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Functional scales &#40;median &#91;IR&#93;&#41;</span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Barthel index&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">90 &#40;50&#8211;100&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">100 &#40;85&#8211;100&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;&#46;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Modified Rankin scale&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#46;0 &#40;0&#46;0&#8211;4&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#46;0 &#40;0&#46;0&#8211;2&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;&#46;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
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    "bibliografia" => array:2 [
      "titulo" => "References"
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          "identificador" => "bibs0005"
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            0 => array:3 [
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Article information
ISSN: 21735808
Original language: English
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2023 May 15 5 20
2023 April 7 3 10
2023 March 10 5 15
2023 February 23 2 25
2023 January 16 12 28
2022 December 20 6 26
2022 November 36 7 43
2022 October 13 8 21
2022 September 27 8 35
2022 August 33 7 40
2022 July 20 9 29
2022 June 20 8 28
2022 May 9 5 14
2022 April 39 6 45
2022 March 37 10 47
2022 February 13 5 18
2022 January 35 10 45
2021 December 40 9 49
2021 November 24 13 37
2021 October 35 14 49
2021 September 39 8 47
2021 August 43 6 49
2021 July 18 9 27
2021 June 20 11 31
2021 May 13 6 19
2021 April 22 8 30
2021 March 16 9 25
2021 February 31 9 40
2021 January 28 7 35
2020 December 24 3 27
2020 November 11 6 17
2020 October 12 1 13
2020 September 15 8 23
2020 August 15 5 20
2020 July 8 6 14
2020 June 4 2 6
2020 May 10 10 20
2020 April 15 1 16
2020 March 16 5 21
2020 February 9 4 13
2020 January 17 6 23
2019 December 10 4 14
2019 November 10 6 16
2019 October 6 8 14
2019 September 12 7 19
2019 August 6 3 9
2019 July 6 7 13
2019 June 28 11 39
2019 May 105 14 119
2019 April 14 13 27
2019 March 6 5 11
2019 February 7 8 15
2019 January 6 5 11
2018 December 6 11 17
2018 November 6 3 9
2018 October 7 4 11
2018 September 10 4 14
2018 August 2 0 2
2018 July 2 1 3
2018 June 3 1 4
2018 May 5 2 7
2018 April 3 0 3
2018 March 3 0 3
2018 February 4 0 4
2018 January 1 0 1
2017 December 3 0 3
2017 November 4 0 4
2017 October 6 1 7
2017 September 12 0 12
2017 August 13 3 16
2017 July 9 2 11
2017 June 13 7 20
2017 May 22 2 24
2017 April 12 1 13
2017 March 5 1 6
2017 February 7 1 8
2017 January 10 2 12
2016 December 7 3 10
2016 November 3 2 5
2016 October 13 3 16
2016 September 9 2 11
2016 August 21 2 23
2016 July 13 1 14
2016 June 13 3 16
2016 May 14 17 31
2016 April 9 12 21
2016 March 17 20 37
2016 February 12 4 16
2016 January 6 5 11
2015 December 5 4 9
2015 November 11 5 16
2015 October 15 6 21
2015 September 11 3 14
2015 August 10 6 16
2015 July 10 6 16
2015 June 3 2 5
2015 May 18 2 20
2015 April 18 7 25
2015 March 25 4 29
2015 February 17 4 21
2015 January 27 10 37
2014 December 37 20 57
2014 November 16 6 22
2014 October 25 2 27
2014 September 13 1 14
2014 August 30 8 38
2014 July 20 8 28
2014 June 4 2 6
2014 May 19 2 21
2014 April 8 3 11
2014 March 21 6 27
2014 February 11 2 13
2014 January 10 5 15
2013 December 15 2 17
2013 November 17 5 22
2013 October 19 0 19
2013 September 25 6 31
2013 August 31 4 35
2013 July 17 1 18
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es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos