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Spanish translation and adaptation of the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) form A in a pilot sample
Traducción y adaptación española de la batería neuropsicológica Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) forma A en una muestra piloto
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"apellidos" => "Aguilar Barbera" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Unidad de Diagnóstico y Tratamiento de las Demencias, Hospital Universitari Mútua de Terrassa, Terrassa, Barcelona, Spain" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Institut de Sociologia i Psicologia Aplicades (ISPA), Barcelona, Spain" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Traducción y adaptación española de la batería neuropsicológica Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) forma A en una muestra piloto" ] ] "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Introduction/objective</span><p id="par0005" class="elsevierStylePara elsevierViewall">It is widely accepted that researchers must have normative data that has been duly validated and culturally adapted in order to ensure that assessments of cognitive performance contain the lowest amount of contamination from other factors.<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> This objective was clearly outlined for the Neuronorma Project, an extensive Spanish study that was published recently.<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">Neuropsychological evaluation (NPE) for dementia may be more or less extensive and detailed depending on the complexity of the evaluation tools in use: brief scales, functional scales, simple test batteries, complex test batteries, and ideographic studies.<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> The most recommendable method for performing NPE for dementia is to use a multidimensional test battery with psychometric properties including sensitive tests for each cognitive area.<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> NPE is a key procedure in diagnosing, classifying, and monitoring the course of mild cognitive impairment, Alzheimer's disease, and other types of dementia.<a class="elsevierStyleCrossRefs" href="#bib0025"><span class="elsevierStyleSup">5,6</span></a> The RBANS battery<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a> is a multidimensional neuropsychological evaluation method that includes a series of different tests. Results from these tests establish performance patterns that characterise certain brain lesions or syndromes. This simple test battery is similar to some that are already in use in Spain, such as the Barcelona Test (<span class="elsevierStyleItalic">Programa Integrado de Exploración Neuropsicológica-Test Barcelona</span>).<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a> Other brief test batteries include the Mattis Dementia Rating Scale,<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">8</span></a> the Cambridge Cognitive Examination included in the Cambridge Mental Disorders of the Elderly Examination,<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">9</span></a> and other more specific tests for dementia, such as the Alzheimer's Disease Assessment Scale<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">10</span></a> or the Consortium to Establish a Registry for Alzheimer's Disease.<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">11</span></a> RBANS presents a number of advantages; it is quite brief compared to other test batteries, and provides 2 parallel evaluations (forms A and B) designed to eliminate the learning effect. Administration time is approximately 30<span class="elsevierStyleHsp" style=""></span>minutes, and the battery is presented in a one-to-one setting by a neuropsychologist trained in administering the test.</p><p id="par0015" class="elsevierStylePara elsevierViewall">It evaluates 5 cognitive functions through 12 subtests: attention (digit span and coding); language (image naming and semantic fluency); visuospatial/constructive ability (figure copy and line orientation tests); immediate memory (list learning and story memory); and delayed memory (list learning free recall, list learning recognition, story memory free recall, figure free recall). RBANS was designed for testing adults aged 20 to 89 years.</p><p id="par0020" class="elsevierStylePara elsevierViewall">A preliminary validation study for the RBANS test battery<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">12</span></a> made comparisons between 20 patients with probable Alzheimer-type dementia, 20 patients with Huntingdon's disease, and 40 control subjects. Tests revealed different cognitive profiles for each of the groups. RBANS was shown to be sensitive for the detection and classification of cases of dementia. Assessments of the sensitivity (discrimination capacity) and clinical utility of RBANS were based on data gathered from clinical groups with different neurological and psychiatric problems. The clinical group was composed of 138 patients with a diagnosis of AD, 49 with vascular dementia, 24 with mixed dementia, 15 with AIDS dementia complex, 19 with Huntington's disease, 33 with Parkinson's disease, 13 with depression, 59 with schizophrenia, and 31 with head trauma.</p><p id="par0025" class="elsevierStylePara elsevierViewall">Since the late 1990s, a number of different studies on the utility and psychometric properties of the RBANS have been published.<a class="elsevierStyleCrossRefs" href="#bib0065"><span class="elsevierStyleSup">13–15</span></a> These studies contrasted findings in normal ageing<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">16</span></a> with those from other diseases, including schizophrenia, other psychotic disorders, and dementia<a class="elsevierStyleCrossRef" href="#bib0085"><span class="elsevierStyleSup">17</span></a> (Parkinson's disease<a class="elsevierStyleCrossRef" href="#bib0090"><span class="elsevierStyleSup">18</span></a> or head injury<a class="elsevierStyleCrossRef" href="#bib0095"><span class="elsevierStyleSup">19</span></a>).</p><p id="par0030" class="elsevierStylePara elsevierViewall">This test battery has been translated and adapted to other languages, including Japanese,<a class="elsevierStyleCrossRef" href="#bib0100"><span class="elsevierStyleSup">20</span></a> Russian,<a class="elsevierStyleCrossRef" href="#bib0105"><span class="elsevierStyleSup">21</span></a> and Hungarian,<a class="elsevierStyleCrossRef" href="#bib0110"><span class="elsevierStyleSup">22</span></a> but no Spanish-language versions had been published.</p><p id="par0035" class="elsevierStylePara elsevierViewall">The purpose of this study is to prepare a Spanish version of form A of the test battery and obtain other preliminary psychometric data from a Spanish population sample. Our aim was to gather a minimally representative sample containing subjects of different ages and educational backgrounds. It must be stated, however, that analysing sociodemographic influences falls outside the scope of this preliminary study.</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Subjects and methods</span><p id="par0040" class="elsevierStylePara elsevierViewall">A consecutive sample was recruited among the companions of patients referred to the dementia diagnosis and treatment unit at Hospital Universitari Mútua, Terrassa, by other care centres and volunteer associations serving the general population. The project was publicised by word of mouth. All participants were unpaid volunteers. All subjects were informed about the purpose of the study in terms they were able to understand, and they were asked to grant verbal consent. We recruited a total of 73 subjects meeting the following criteria:<ul class="elsevierStyleList" id="lis0005"><li class="elsevierStyleListItem" id="lsti0005"><p id="par0045" class="elsevierStylePara elsevierViewall">Inclusion criteria: (a) residence in Spain; (b) acceptance of terms of participation by verbally providing informed consent; (c) age between 40 and 80 years; (d) basic reading and writing skills; (e) having sufficient hearing, sight, and physical fitness to complete the test; (f) score on the MMSE equal to or higher than 24; and (g) having a good functional state according to normality criteria on the Blessed Dementia Rating Scale (BDRS).<a class="elsevierStyleCrossRef" href="#bib0120"><span class="elsevierStyleSup">24</span></a></p></li><li class="elsevierStyleListItem" id="lsti0010"><p id="par0050" class="elsevierStylePara elsevierViewall">Exclusion criteria: (a) any type of CNS condition affecting cognition and/or functional abilities; (b) history of CNS infections (meningitis, encephalitis, etc.); (c) lack of any present or past history of severe psychiatric illness according to DSM-IV criteria; (d) clinically significant hypothyroidism; (e) known metabolic changes; (f) history or presence of alcohol or other drug abuse in the preceding 24 months, and (g) presence of any factor that rendered the subject's participation inappropriate according to the lead researcher's judgement.</p></li></ul></p><p id="par0055" class="elsevierStylePara elsevierViewall">We generated a satisfactory Spanish translation equivalent to the original version by using the different steps in the forward-translation/back-translation method, together with qualitative methodology<a class="elsevierStyleCrossRefs" href="#bib0125"><span class="elsevierStyleSup">25,26</span></a> in discussion groups to lend nuances to the list learning and list learning recognition subtests.</p><p id="par0060" class="elsevierStylePara elsevierViewall">We first obtained 2 translations from English to Spanish prepared independently by translators (bilingual native Spanish speakers) with no prior knowledge of the RBANS test battery. The research team, composed of neuropsychologists, then compared the 2 translations to obtain the first consensus version. Subsequently, 2 researchers from outside the research team evaluated the first version and provided suggestions for improving its conceptual equivalence and expression. Questionable items were then identified and alternative wordings were proposed. The team reworded certain items to minimise any differences between the translated version and the original.</p><p id="par0065" class="elsevierStylePara elsevierViewall">The research team evaluated any items and responses having questionable conceptual equivalence or being expressed in an unnatural or incorrect way and made the appropriate changes to create the second consensus version. A native English-speaking translator then used that version to prepare the back-translation from Spanish to English. We then compared the back-translation to the original version as a committee to detect any potential semantic changes. This resulted in the pilot version of the test. We then tested the pilot version to check the viability of the test battery. These steps produced the definitive Spanish-language version.</p><p id="par0070" class="elsevierStylePara elsevierViewall">Only the testing instructions and scoring criteria were translated to produce the adapted versions of non-verbal subtests. The shape of the geometrical figure, the line orientation, and the number code all corresponded to those in the original version.</p><p id="par0075" class="elsevierStylePara elsevierViewall">For verbal tests such as the list learning and list learning recognition subtests, we were mindful of factors such as word frequency, imagery, phonemic and semantic similarity, and word length.<a class="elsevierStyleCrossRef" href="#bib0065"><span class="elsevierStyleSup">13</span></a> In some cases, it was impossible to meet all equivalence criteria and we focused primarily on frequency and imagery, as the research team's review of the literature revealed that these considerations usually took priority over others.<a class="elsevierStyleCrossRefs" href="#bib0070"><span class="elsevierStyleSup">14–16</span></a> Psycholinguistic criteria were therefore held to be more important than semantic equivalence. The story memory subtest contained a logical problem described as taking place in Cleveland on the original test. When determining an equivalent for the adapted version, we searched for a Spanish city with the same size ratio compared to Madrid as Cleveland has compared to Washington, D.C.</p><p id="par0080" class="elsevierStylePara elsevierViewall">All participants were evaluated in a single session in which the Spanish version of the RBANS test battery was administered alongside the MMSE, an internationally-recognised cognitive screening test.<a class="elsevierStyleCrossRef" href="#bib0115"><span class="elsevierStyleSup">23</span></a> Functional state was evaluated using the BDRS.<a class="elsevierStyleCrossRef" href="#bib0120"><span class="elsevierStyleSup">24</span></a></p><p id="par0085" class="elsevierStylePara elsevierViewall">We used SPSS software version 11.0 for Windows for data analysis and performed a descriptive study of the test variables. Correlations between the indices of different scales were determined using the parametric Pearson correlation. <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span><<span class="elsevierStyleHsp" style=""></span>.01 was considered to be statistically significant. The reliability analysis was performed using an internal consistency analysis with Cronbach's alpha index.</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Results</span><p id="par0090" class="elsevierStylePara elsevierViewall">The Spanish translation of the RBANS test battery was created following the method outlined above. That translation is provided as <a class="elsevierStyleCrossRef" href="#sec0030">Annex 1</a>.</p><p id="par0095" class="elsevierStylePara elsevierViewall">For information purposes only, <a class="elsevierStyleCrossRefs" href="#tbl0005">Tables 1 and 2</a> provide descriptive sociodemographic data for the sample; these data reveal a predominance of women, who account for 66% of the participants. Regarding age and educational level, most participants were either in the 50 to 59 age group (with average to high educational levels) or in the 70 to 79 age group (with similar educational levels); this difference was not statistically significant. All the different age groups and educational levels included in our study were represented, even if representation was minimal.</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><p id="par0100" class="elsevierStylePara elsevierViewall">Cronbach alpha provided an overall reliability coefficient of 0.73 for the translated and adapted version of the RBANS neuropsychological test battery.</p><p id="par0105" class="elsevierStylePara elsevierViewall">While all of the correlations were statistically significant (see <a class="elsevierStyleCrossRef" href="#tbl0015">Table 3</a>), the most consistently obtained correlations (<span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>><span class="elsevierStyleHsp" style=""></span>.01) were between immediate memory and 3 other indices: delayed memory (0.68), attention (0.48) and visuospatial capacity (0.38). There were also consistent correlations between visuospatial capacity and 2 other indices: attention (0.51) and delayed memory (0.44).</p><elsevierMultimedia ident="tbl0015"></elsevierMultimedia><p id="par0110" class="elsevierStylePara elsevierViewall">For a level of <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span><<span class="elsevierStyleHsp" style=""></span>.05, language was correlated with all other indices, as were attention and delayed memory.</p><p id="par0115" class="elsevierStylePara elsevierViewall">In turn, we also found a statistically significant correlation (<span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span><<span class="elsevierStyleHsp" style=""></span>.01) between the MMSE and the following indices: immediate memory (0.44), delayed memory (0.33), and visuospatial capacity (0.32). For all other indices, correlations were significant for a limit of 0.05 (<a class="elsevierStyleCrossRef" href="#tbl0015">Table 3</a>).</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Discussion</span><p id="par0120" class="elsevierStylePara elsevierViewall">Firstly, we will address the nuances of the translation. Literal translation of a neuropsychological evaluation tool is out of the question, since the tool must reflect cultural peculiarities, as stated above.<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1,2</span></a> Terms and sometimes even concepts have therefore had to be modified; semantic categories have also been changed according to psycholinguistic criteria, such as the term's frequency of use and its imagery.</p><p id="par0125" class="elsevierStylePara elsevierViewall">One of the limitations of the test is that since it is a brief test battery, it is unable to evaluate all of the cognitive functions that may be altered in patients with focal or diffuse brain injury. We therefore face the well-known dilemma of having to choose between a test of a viable length and a test that is exhaustive. Depending on the patient being assessed, the neuropsychologist will have to recur to the versatility of NPE<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> in order to evaluate functions that are not considered by the test battery, such as people recognition and orientation in place and time, sensory perception, ideomotor praxis, and the executive functions. The latter can only be measured using the semantic fluency subtest.</p><p id="par0130" class="elsevierStylePara elsevierViewall">The test shows good reliability, that is, accuracy in measuring the variables it purports to measure, as shown by the internal consistency analysis. With a Cronbach alpha of 0.73, the Spanish adaptation of the RBANS is adequate.</p><p id="par0135" class="elsevierStylePara elsevierViewall">Statistically significant positive correlations are present between all of the subtests on the Spanish version, and correlations are similar to those in the original. For example, the indices for immediate memory and delayed memory show a correlation of 0.63 in the Spanish version and 0.68 in the original. Likewise, we found that correlations between indices for the Spanish version and the original were very similar between immediate memory and visuospatial capacity (0.38; original, 0.28) or attention (0.48; original, 0.40); and between visuospatial capacity and attention (0.51; original, 0.32) or delayed memory (0.44; original 0.35). Where differences can be observed, the Spanish version shows a greater degree of correlation. This is indicative of covariation between different indices.</p><p id="par0140" class="elsevierStylePara elsevierViewall">Based on these results, we maintain that this Spanish-language adaptation of the RBANS test battery shows acceptable psychometric properties with overall internal consistency and significant positive correlations. It may therefore be considered a useful tool for assessing cognitive state in the Spanish population.</p><p id="par0145" class="elsevierStylePara elsevierViewall">It must be said that this is a preliminary study designed to produce a Spanish-language translation and adaptation of the RBANS. At present, we are completing an expanded normalisation study on this tool and normalising data in adults older than 40. This study will provide an analysis of the influence of different sociodemographic variables and others. We also believe that it would be a positive step to obtain validation data by studying test results from subjects with varying degrees of cognitive impairment.</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Conflicts of interest</span><p id="par0150" class="elsevierStylePara elsevierViewall">The authors have no conflicts of interest to declare.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:11 [ 0 => array:2 [ "identificador" => "xres170124" "titulo" => array:5 [ 0 => "Abstract" 1 => "Introduction" 2 => "Patients and methods" 3 => "Results" 4 => "Conclusions" ] ] 1 => array:2 [ "identificador" => "xpalclavsec158191" "titulo" => "Keywords" ] 2 => array:2 [ "identificador" => "xres170123" "titulo" => array:5 [ 0 => "Resumen" 1 => "Introducción" 2 => "Pacientes y métodos" 3 => "Resultados" 4 => "Conclusiones" ] ] 3 => array:2 [ "identificador" => "xpalclavsec158190" "titulo" => "Palabras clave" ] 4 => array:2 [ "identificador" => "sec0005" "titulo" => "Introduction/objective" ] 5 => array:2 [ "identificador" => "sec0010" "titulo" => "Subjects and methods" ] 6 => array:2 [ "identificador" => "sec0015" "titulo" => "Results" ] 7 => array:2 [ "identificador" => "sec0020" "titulo" => "Discussion" ] 8 => array:2 [ "identificador" => "sec0025" "titulo" => "Conflicts of interest" ] 9 => array:2 [ "identificador" => "xack44780" "titulo" => "Acknowledgements" ] 10 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2011-05-17" "fechaAceptado" => "2011-07-13" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec158191" "palabras" => array:6 [ 0 => "Adaptation" 1 => "Cognitive functions" 2 => "Neuropsychology" 3 => "Repeatable Battery for the Assessment of Neuropsychological Status" 4 => "Spanish version" 5 => "Validation" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec158190" "palabras" => array:6 [ 0 => "Adaptación" 1 => "Funciones cognitivas" 2 => "Neuropsicología" 3 => "Repeatable Battery for the Assessment of Neuropsychological Status" 4 => "Validación" 5 => "Versión española" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span class="elsevierStyleSectionTitle">Introduction</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">RBANS is a short neuropsychological battery which has shown to be sensitive in detecting cognitive impairment in degenerative and non-degenerative diseases. It has been translated and adapted to different languages and is widely used in other countries, but no Spanish version has been published.</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">The objective was to make a valid translation of the RBANS to Spanish, and obtain a version adapted to the Spanish population.</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">The study included 73 subjects: 25 males with a mean age of 54 years and 9.72 years of education, and 48 females with a mean age of 53 years and 10.29 years of education. The battery was translated using the translation-back-translation method (with slight differences), followed by a descriptive pilot study in a sample of the normal population.</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">An overall reliability coefficient with a Cronbach alpha of 0.73 was obtained in the translation and adaptation of the RBANS, form A (1998). Statistically significant positive correlations between the indices were obtained.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">The version translated and adapted to Spanish performs similarly to the original version.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span class="elsevierStyleSectionTitle">Introducción</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">La RBANS es una batería neuropsicológica breve que se ha mostrado sensible para la detección de trastorno cognitivo en patología degenerativa y no degenerativa. Ha sido traducida y adaptada a diversas lenguas y es ampliamente utilizada en otros países, pero no se ha publicado ninguna versión española.</p><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">El objetivo es realizar una traducción válida al español de la RBANS y obtener una versión adaptada a la población española.</p> <span class="elsevierStyleSectionTitle">Pacientes y métodos</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Participaron 73 sujetos, 25 hombres, con una edad media de 54 años y escolaridad de 9,72, y 48 mujeres, con edad media de 53 y escolaridad 10,29. Se realizó una traducción mediante el método traducción-retrotraducción (con matices) y posteriormente se realizó un estudio descriptivo piloto en una muestra de población normal.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">En la traducción y la adaptación de la batería neuropsicológica RBANS forma A (1998) se obtuvo un coeficiente de fiabilidad global con una alfa de Cronbach de 0,73. Se obtuvieron correlaciones positivas, estadísticamente significativas entre los índices.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">La versión traducida y adaptada al castellano se comporta de forma similar a la versión original.</p>" ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara">Please cite this article as: Muntal Encinas, et al. Traducción y adaptación española de la batería neuropsicológica Repeat table Battery for the Assessment of Neuropsychological Status (RBANS) forma A en una muestra piloto. Neurología 2012;27:531–46.</p>" ] ] "apendice" => array:1 [ 0 => array:1 [ "seccion" => array:1 [ 0 => array:4 [ "apendice" => "<p id="par0165" class="elsevierStylePara elsevierViewall"><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><elsevierMultimedia ident="fig0020"></elsevierMultimedia><elsevierMultimedia ident="fig0025"></elsevierMultimedia><elsevierMultimedia ident="fig0030"></elsevierMultimedia><elsevierMultimedia ident="fig0035"></elsevierMultimedia><elsevierMultimedia ident="fig0040"></elsevierMultimedia><elsevierMultimedia ident="fig0045"></elsevierMultimedia><elsevierMultimedia ident="fig0050"></elsevierMultimedia><elsevierMultimedia ident="fig0055"></elsevierMultimedia><elsevierMultimedia ident="fig0060"></elsevierMultimedia></p>" "etiqueta" => "Annex 1" "titulo" => "Spanish version" "identificador" => "sec0030" ] ] ] ] "multimedia" => array:15 [ 0 => array:7 [ "identificador" => "tbl0005" "etiqueta" => "Table 1" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "tabla" => array:2 [ "leyenda" => "<p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">SD: standard deviation.</p>" "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">Men (mean<span class="elsevierStyleHsp" style=""></span>±<span class="elsevierStyleHsp" style=""></span>SD) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">Women (mean<span class="elsevierStyleHsp" style=""></span>±<span class="elsevierStyleHsp" style=""></span>SD) \t\t\t\t\t\t\n \t\t\t\t</td></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Age (years) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">54<span class="elsevierStyleHsp" style=""></span>±<span class="elsevierStyleHsp" style=""></span>9.86 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">53<span class="elsevierStyleHsp" style=""></span>±<span class="elsevierStyleHsp" style=""></span>9.02 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Participants \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">34% (<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>25) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">66% (<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>53) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Education (years) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">9.72<span class="elsevierStyleHsp" style=""></span>±<span class="elsevierStyleHsp" style=""></span>4.55 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">10.29<span class="elsevierStyleHsp" style=""></span>±<span class="elsevierStyleHsp" style=""></span>3.70 \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab265001.png" ] ] ] ] "descripcion" => array:1 [ "en" => "<p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Descriptive data for the sample.</p>" ] ] 1 => array:7 [ "identificador" => "tbl0010" "etiqueta" => "Table 2" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "tabla" => array:1 [ "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">Education \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">40–49 years \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">50–59 years \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">60–69 years \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">70–79 years \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">Total \t\t\t\t\t\t\n \t\t\t\t</td></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0–6 years \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">3 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">8 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">7–12 years \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">8 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">5 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">15 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">30 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><12 years \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">19 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">13 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">35 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Total \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">7 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">28 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">8 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">30 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">73 \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab265002.png" ] ] ] ] "descripcion" => array:1 [ "en" => "<p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">Sample broken down by age and education.</p>" ] ] 2 => array:7 [ "identificador" => "tbl0015" "etiqueta" => "Table 3" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "tabla" => array:2 [ "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">Indices \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">Immediate memory \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">Delayed memory \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">Attention \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">Visuospatial capacity \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">Language \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" style="border-bottom: 2px solid black">MMSE \t\t\t\t\t\t\n \t\t\t\t</td></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Immediate memory \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.68<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.48<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.38<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.20 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.44<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a> \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Delayed memory \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.68<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.52 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.44<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.08 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.33<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a> \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Attention \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.48<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.52 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.51<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.25 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.17 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Visuospatial capacity \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.38<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.44<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.51<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.24 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.32<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a> \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Language \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.20 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.08 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.25 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.24 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.17 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">MMSE \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.44<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.33<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.17 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.32<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.17 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab265003.png" ] ] ] "notaPie" => array:1 [ 0 => array:3 [ "identificador" => "tblfn0005" "etiqueta" => "a" "nota" => "<p class="elsevierStyleNotepara">Correlation is statistically significant at 0.01 (bilateral). 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 7 | 9 | 16 |
| 2024 October | 30 | 9 | 39 |
| 2024 September | 63 | 13 | 76 |
| 2024 August | 45 | 6 | 51 |
| 2024 July | 29 | 6 | 35 |
| 2024 June | 37 | 11 | 48 |
| 2024 May | 48 | 11 | 59 |
| 2024 April | 37 | 8 | 45 |
| 2024 March | 71 | 11 | 82 |
| 2024 February | 95 | 25 | 120 |
| 2024 January | 89 | 32 | 121 |
| 2023 December | 96 | 9 | 105 |
| 2023 November | 112 | 15 | 127 |
| 2023 October | 165 | 25 | 190 |
| 2023 September | 108 | 11 | 119 |
| 2023 August | 99 | 19 | 118 |
| 2023 July | 148 | 40 | 188 |
| 2023 June | 94 | 24 | 118 |
| 2023 May | 138 | 15 | 153 |
| 2023 April | 115 | 12 | 127 |
| 2023 March | 114 | 11 | 125 |
| 2023 February | 97 | 15 | 112 |
| 2023 January | 114 | 20 | 134 |
| 2022 December | 87 | 17 | 104 |
| 2022 November | 146 | 19 | 165 |
| 2022 October | 118 | 26 | 144 |
| 2022 September | 89 | 29 | 118 |
| 2022 August | 96 | 26 | 122 |
| 2022 July | 102 | 23 | 125 |
| 2022 June | 74 | 7 | 81 |
| 2022 May | 65 | 14 | 79 |
| 2022 April | 91 | 26 | 117 |
| 2022 March | 121 | 28 | 149 |
| 2022 February | 128 | 19 | 147 |
| 2022 January | 177 | 10 | 187 |
| 2021 December | 107 | 17 | 124 |
| 2021 November | 122 | 16 | 138 |
| 2021 October | 167 | 24 | 191 |
| 2021 September | 156 | 22 | 178 |
| 2021 August | 118 | 8 | 126 |
| 2021 July | 83 | 13 | 96 |
| 2021 June | 78 | 14 | 92 |
| 2021 May | 97 | 17 | 114 |
| 2021 April | 222 | 48 | 270 |
| 2021 March | 130 | 9 | 139 |
| 2021 February | 83 | 11 | 94 |
| 2021 January | 95 | 18 | 113 |
| 2020 December | 105 | 12 | 117 |
| 2020 November | 104 | 15 | 119 |
| 2020 October | 65 | 7 | 72 |
| 2020 September | 50 | 18 | 68 |
| 2020 August | 95 | 23 | 118 |
| 2020 July | 57 | 10 | 67 |
| 2020 June | 59 | 13 | 72 |
| 2020 May | 67 | 17 | 84 |
| 2020 April | 55 | 10 | 65 |
| 2020 March | 79 | 16 | 95 |
| 2020 February | 639 | 11 | 650 |
| 2020 January | 95 | 10 | 105 |
| 2019 December | 82 | 20 | 102 |
| 2019 November | 50 | 11 | 61 |
| 2019 October | 64 | 10 | 74 |
| 2019 September | 88 | 24 | 112 |
| 2019 August | 51 | 5 | 56 |
| 2019 July | 77 | 13 | 90 |
| 2019 June | 108 | 21 | 129 |
| 2019 May | 218 | 52 | 270 |
| 2019 April | 118 | 26 | 144 |
| 2019 March | 37 | 5 | 42 |
| 2019 February | 53 | 9 | 62 |
| 2019 January | 41 | 11 | 52 |
| 2018 December | 46 | 4 | 50 |
| 2018 November | 65 | 10 | 75 |
| 2018 October | 53 | 7 | 60 |
| 2018 September | 229 | 27 | 256 |
| 2018 August | 80 | 1 | 81 |
| 2018 July | 108 | 13 | 121 |
| 2018 June | 86 | 5 | 91 |
| 2018 May | 86 | 8 | 94 |
| 2018 April | 80 | 7 | 87 |
| 2018 March | 72 | 1 | 73 |
| 2018 February | 54 | 5 | 59 |
| 2018 January | 52 | 2 | 54 |
| 2017 December | 63 | 0 | 63 |
| 2017 November | 49 | 2 | 51 |
| 2017 October | 62 | 2 | 64 |
| 2017 September | 54 | 5 | 59 |
| 2017 August | 68 | 7 | 75 |
| 2017 July | 59 | 4 | 63 |
| 2017 June | 67 | 5 | 72 |
| 2017 May | 115 | 14 | 129 |
| 2017 April | 54 | 5 | 59 |
| 2017 March | 76 | 13 | 89 |
| 2017 February | 130 | 0 | 130 |
| 2017 January | 62 | 3 | 65 |
| 2016 December | 81 | 9 | 90 |
| 2016 November | 202 | 6 | 208 |
| 2016 October | 164 | 11 | 175 |
| 2016 September | 333 | 12 | 345 |
| 2016 August | 323 | 7 | 330 |
| 2016 July | 147 | 7 | 154 |
| 2016 June | 129 | 16 | 145 |
| 2016 May | 110 | 22 | 132 |
| 2016 April | 108 | 26 | 134 |
| 2016 March | 104 | 22 | 126 |
| 2016 February | 80 | 15 | 95 |
| 2016 January | 87 | 21 | 108 |
| 2015 December | 72 | 15 | 87 |
| 2015 November | 89 | 12 | 101 |
| 2015 October | 115 | 17 | 132 |
| 2015 September | 73 | 9 | 82 |
| 2015 August | 121 | 14 | 135 |
| 2015 July | 157 | 15 | 172 |
| 2015 June | 88 | 6 | 94 |
| 2015 May | 95 | 20 | 115 |
| 2015 April | 109 | 9 | 118 |
| 2015 March | 177 | 9 | 186 |
| 2015 February | 80 | 3 | 83 |
| 2015 January | 43 | 8 | 51 |
| 2014 December | 41 | 7 | 48 |
| 2014 November | 26 | 6 | 32 |
| 2014 October | 39 | 9 | 48 |
| 2014 September | 41 | 8 | 49 |
| 2014 August | 58 | 4 | 62 |
| 2014 July | 34 | 9 | 43 |
| 2014 June | 23 | 6 | 29 |
| 2014 May | 30 | 3 | 33 |
| 2014 April | 32 | 4 | 36 |
| 2014 March | 41 | 4 | 45 |
| 2014 February | 25 | 4 | 29 |
| 2014 January | 25 | 6 | 31 |
| 2013 December | 33 | 1 | 34 |
| 2013 November | 49 | 4 | 53 |
| 2013 October | 74 | 10 | 84 |
| 2013 September | 69 | 6 | 75 |
| 2013 August | 53 | 6 | 59 |
| 2013 July | 27 | 5 | 32 |
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