was read the article
array:25 [ "pii" => "S217358081930135X" "issn" => "21735808" "doi" => "10.1016/j.nrleng.2017.12.009" "estado" => "S300" "fechaPublicacion" => "2021-04-01" "aid" => "1185" "copyright" => "Sociedad Española de Neurología" "copyrightAnyo" => "2018" "documento" => "article" "crossmark" => 1 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "fla" "cita" => "Neurologia. 2021;36:215-21" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 138 "formatos" => array:3 [ "EPUB" => 39 "HTML" => 67 "PDF" => 32 ] ] "Traduccion" => array:1 [ "es" => array:20 [ "pii" => "S0213485318300252" "issn" => "02134853" "doi" => "10.1016/j.nrl.2017.12.008" "estado" => "S300" "fechaPublicacion" => "2021-04-01" "aid" => "1185" "copyright" => "Sociedad Española de Neurología" "documento" => "article" "crossmark" => 1 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "fla" "cita" => "Neurologia. 2021;36:215-21" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1599 "formatos" => array:3 [ "EPUB" => 61 "HTML" => 1063 "PDF" => 475 ] ] "es" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original</span>" "titulo" => "Pronóstico al año de la hemorragia subaracnoidea cortical no traumática: Serie prospectiva de 34 pacientes" "tienePdf" => "es" "tieneTextoCompleto" => "es" "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "215" "paginaFinal" => "221" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "One-year prognosis of non-traumatic cortical subarachnoid haemorrhage: A prospective series of 34 patients" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figura 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 825 "Ancho" => 2000 "Tamanyo" => 132296 ] ] "descripcion" => array:1 [ "es" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Paciente de 82 años que, 6 días después de colocar un stent carotideo izquierdo, presenta pérdida de fuerza y sensibilidad en brazo derecho de inicio brusco. En el TAC cerebral (A) se aprecia una HSAc en la convexidad del lado izquierdo. La RM en secuencia de difusión (B) identifica un infarto agudo adyacente al sangrado. La angio-RM (C) muestra una trombosis del stent (flecha).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "R.F. Galiano Blancart, G. Fortea, A. Pampliega Pérez, S. Martí, V. Parkhutik, A.V. Sánchez Cruz, C. Soriano, D. Geffner Sclarsky, M.T. Pérez Saldaña, N. López Hernández, I. Beltrán, A. Lago Martín" "autores" => array:13 [ 0 => array:2 [ "nombre" => "R.F." "apellidos" => "Galiano Blancart" ] 1 => array:2 [ "nombre" => "G." "apellidos" => "Fortea" ] 2 => array:2 [ "nombre" => "A." "apellidos" => "Pampliega Pérez" ] 3 => array:2 [ "nombre" => "S." "apellidos" => "Martí" ] 4 => array:2 [ "nombre" => "V." "apellidos" => "Parkhutik" ] 5 => array:2 [ "nombre" => "A.V." "apellidos" => "Sánchez Cruz" ] 6 => array:2 [ "nombre" => "C." "apellidos" => "Soriano" ] 7 => array:2 [ "nombre" => "D." "apellidos" => "Geffner Sclarsky" ] 8 => array:2 [ "nombre" => "M.T." "apellidos" => "Pérez Saldaña" ] 9 => array:2 [ "nombre" => "N." "apellidos" => "López Hernández" ] 10 => array:2 [ "nombre" => "I." "apellidos" => "Beltrán" ] 11 => array:2 [ "nombre" => "A." "apellidos" => "Lago Martín" ] 12 => array:1 [ "colaborador" => "por el Grupo Ictus-Comunidad Valenciana" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S217358081930135X" "doi" => "10.1016/j.nrleng.2017.12.009" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S217358081930135X?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0213485318300252?idApp=UINPBA00004N" "url" => "/02134853/0000003600000003/v1_202103200928/S0213485318300252/v1_202103200928/es/main.assets" ] ] "itemSiguiente" => array:20 [ "pii" => "S2173580819301063" "issn" => "21735808" "doi" => "10.1016/j.nrleng.2017.09.008" "estado" => "S300" "fechaPublicacion" => "2021-04-01" "aid" => "1156" "copyright" => "Sociedad Española de Neurología" "documento" => "article" "crossmark" => 1 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "rev" "cita" => "Neurologia. 2021;36:222-8" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 183 "formatos" => array:3 [ "EPUB" => 28 "HTML" => 85 "PDF" => 70 ] ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Review article</span>" "titulo" => "Stroke and cannabis use in patients with no cardiovascular risk factors: a systematic review of case reports" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "222" "paginaFinal" => "228" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Ictus y consumo de cannabis en pacientes sin factores de riesgo cardiovascular: revisión sistemática de casos clínicos" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1371 "Ancho" => 2500 "Tamanyo" => 177566 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Flow diagram summarising the article selection process.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "S.A. Gómez Ochoa" "autores" => array:1 [ 0 => array:2 [ "nombre" => "S.A." "apellidos" => "Gómez Ochoa" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0213485317303626" "doi" => "10.1016/j.nrl.2017.09.016" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0213485317303626?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173580819301063?idApp=UINPBA00004N" "url" => "/21735808/0000003600000003/v1_202103190809/S2173580819301063/v1_202103190809/en/main.assets" ] "itemAnterior" => array:20 [ "pii" => "S2173580819301373" "issn" => "21735808" "doi" => "10.1016/j.nrleng.2017.12.010" "estado" => "S300" "fechaPublicacion" => "2021-04-01" "aid" => "1186" "copyright" => "Sociedad Española de Neurología" "documento" => "article" "crossmark" => 1 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "fla" "cita" => "Neurologia. 2021;36:209-14" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 128 "formatos" => array:3 [ "EPUB" => 59 "HTML" => 45 "PDF" => 24 ] ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original article</span>" "titulo" => "Usefulness of optic nerve ultrasound to predict clinical progression in multiple sclerosis" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "209" "paginaFinal" => "214" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Utilidad de la ecografía de nervio óptico como predictor de progresión en esclerosis múltiple" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1134 "Ancho" => 850 "Tamanyo" => 52194 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Ocular ultrasound: longitudinal image of the optic nerve from a patient with multiple sclerosis.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "S. Pérez Sánchez, S. Eichau Madueño, M. Rus Hidalgo, A.M. Domínguez Mayoral, A. Vilches-Arenas, G. Navarro Mascarell, G. Izquierdo" "autores" => array:7 [ 0 => array:2 [ "nombre" => "S." "apellidos" => "Pérez Sánchez" ] 1 => array:2 [ "nombre" => "S." "apellidos" => "Eichau Madueño" ] 2 => array:2 [ "nombre" => "M." "apellidos" => "Rus Hidalgo" ] 3 => array:2 [ "nombre" => "A.M." "apellidos" => "Domínguez Mayoral" ] 4 => array:2 [ "nombre" => "A." "apellidos" => "Vilches-Arenas" ] 5 => array:2 [ "nombre" => "G." "apellidos" => "Navarro Mascarell" ] 6 => array:2 [ "nombre" => "G." "apellidos" => "Izquierdo" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0213485318300264" "doi" => "10.1016/j.nrl.2017.12.009" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0213485318300264?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173580819301373?idApp=UINPBA00004N" "url" => "/21735808/0000003600000003/v1_202103190809/S2173580819301373/v1_202103190809/en/main.assets" ] "en" => array:20 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original article</span>" "titulo" => "One-year prognosis of non-traumatic cortical subarachnoid haemorrhage: a prospective series of 34 patients" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "215" "paginaFinal" => "221" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "R.F. Galiano Blancart, G. Fortea, A. Pampliega Pérez, S. Martí, V. Parkhutik, A.V. Sánchez Cruz, C. Soriano, D. Geffner Sclarsky, M.T. Pérez Saldaña, N. López Hernández, I. Beltrán, A. Lago Martín" "autores" => array:13 [ 0 => array:4 [ "nombre" => "R.F." "apellidos" => "Galiano Blancart" "email" => array:1 [ 0 => "rafa_galiano@yahoo.es" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "G." "apellidos" => "Fortea" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "A." "apellidos" => "Pampliega Pérez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] ] 3 => array:3 [ "nombre" => "S." "apellidos" => "Martí" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] ] 4 => array:3 [ "nombre" => "V." "apellidos" => "Parkhutik" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 5 => array:3 [ "nombre" => "A.V." "apellidos" => "Sánchez Cruz" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">d</span>" "identificador" => "aff0020" ] ] ] 6 => array:3 [ "nombre" => "C." "apellidos" => "Soriano" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">e</span>" "identificador" => "aff0025" ] ] ] 7 => array:3 [ "nombre" => "D." "apellidos" => "Geffner Sclarsky" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">e</span>" "identificador" => "aff0025" ] ] ] 8 => array:3 [ "nombre" => "M.T." "apellidos" => "Pérez Saldaña" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">f</span>" "identificador" => "aff0030" ] ] ] 9 => array:3 [ "nombre" => "N." "apellidos" => "López Hernández" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] ] 10 => array:3 [ "nombre" => "I." "apellidos" => "Beltrán" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] ] 11 => array:3 [ "nombre" => "A." "apellidos" => "Lago Martín" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 12 => array:1 [ "colaborador" => "on behalf of Grupo Ictus-Comunidad Valenciana" ] ] "afiliaciones" => array:6 [ 0 => array:3 [ "entidad" => "Servicio de Neurología, Hospital Dr. Peset de Valencia, Valencia, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Neurología, Hospital La Fe de Valencia, Valencia, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Servicio de Neurología, Hospital General de Alicante, Alicante, Spain" "etiqueta" => "c" "identificador" => "aff0015" ] 3 => array:3 [ "entidad" => "Servicio de Neurología, Hospital de Sagunto, Castellón de la Plana, Spain" "etiqueta" => "d" "identificador" => "aff0020" ] 4 => array:3 [ "entidad" => "Servicio de Neurología, Hospitals General de Castellón, Valencia, Spain" "etiqueta" => "e" "identificador" => "aff0025" ] 5 => array:3 [ "entidad" => "Hospital de Manises, Manises, Spain" "etiqueta" => "f" "identificador" => "aff0030" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Pronóstico al año de la hemorragia subaracnoidea cortical no traumática: serie prospectiva de 34 pacientes" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 825 "Ancho" => 2000 "Tamanyo" => 132383 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0250" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Eighty-two-year-old patient presenting sudden-onset loss of strength and sensitivity in the left arm 6 days after implantation of a left carotid stent. A) Head CT scan showing cSAH of the left convexity. B) Diffusion-weighted MRI scan revealing acute infarction adjacent to the bleeding. C) MRI-angiography showing stent thrombosis (arrow).</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">The most frequent cause of non-traumatic subarachnoid haemorrhage (SAH) is the rupture of an intracranial aneurysm, which is recorded in 85% of cases. These patients present familial predisposition, as well as well-known risk factors such as smoking, arterial hypertension, or excessive alcohol consumption. Prognosis is poor, with a case fatality rate of approximately 50%; one-third of survivors remain dependent.<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">The second most frequent cause is perimesencephalic haemorrhage (10% of all cases), in which brain angiography findings are almost always normal and progression is usually satisfactory.<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">The remaining 5% of cases are mainly cortical SAHs (cSAH), which are characterised by the presence of blood in one or several sulci of the brain convexity. Several causes of cSAH are reported<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a>: cerebral amyloid angiopathy (CAA),<a class="elsevierStyleCrossRefs" href="#bib0015"><span class="elsevierStyleSup">3–6</span></a> vaculitis,<a class="elsevierStyleCrossRefs" href="#bib0035"><span class="elsevierStyleSup">7,8</span></a> reversible cerebral vasoconstriction syndrome (RCVS),<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">9</span></a> posterior reversible encephalopathy syndrome (PRES),<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">10</span></a> vascular malformations,<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">11</span></a> mycotic aneurysms,<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">12</span></a> ischaemic stroke,<a class="elsevierStyleCrossRef" href="#bib0065"><span class="elsevierStyleSup">13</span></a> arterial dissection or stenosis,<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">14</span></a> and cerebral venous thrombosis (CVT).<a class="elsevierStyleCrossRefs" href="#bib0075"><span class="elsevierStyleSup">15–17</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">The prognosis of patients with cSAH is not well established, with data available only from small clinical series.<a class="elsevierStyleCrossRefs" href="#bib0090"><span class="elsevierStyleSup">18–23</span></a> Furthermore, no prospective studies providing information on long-term progression have been published.</p><p id="par0025" class="elsevierStylePara elsevierViewall">The aim of this study is to describe the clinical and aetiological characteristics of patients with cSAH, and to determine their progression and prognosis.</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Patients and methods</span><p id="par0030" class="elsevierStylePara elsevierViewall">This is an observational, prospective, multi-centre study, including patients from 6 hospitals from the Valencian Community (Spain). The study was authorised by the Research Committee at Hospital de Sagunto. Informed consent forms were signed in all cases. Patients were recruited between June 2011 and April 2016, with follow-up consultations held at 3 months and one year. Progression was assessed using the modified Rankin Scale, and was considered favourable with a score ≤2 and unfavourable with a score >2.</p><p id="par0035" class="elsevierStylePara elsevierViewall">All patients were admitted to their reference hospitals. We excluded cases of traumatic haemorrhages and haemorrhages with associated intraparenchymal haematoma or bleeding in the interhemispheric fissure, basal cisterns, or ventricles. Clinical, demographic, electrophysiological, laboratory, and imaging data were collected.</p><p id="par0040" class="elsevierStylePara elsevierViewall">All patients underwent a head CT scan. Whether to perform other imaging studies during admission was considered on an individual basis; these studies included CT angiography, brain MRI with vascular study, and conventional cerebral angiography. We also collected data on the presence of superficial siderosis, old haemorrhage, and acute ischaemia on diffusion sequences. We used the modified Boston criteria to diagnose CAA<a class="elsevierStyleCrossRef" href="#bib0120"><span class="elsevierStyleSup">24</span></a> and the Calabrese criteria for RCVS.<a class="elsevierStyleCrossRef" href="#bib0125"><span class="elsevierStyleSup">25</span></a> During follow-up, clinically stable patients did not undergo neuroimaging studies.</p><p id="par0045" class="elsevierStylePara elsevierViewall">A cerebrospinal fluid analysis and/or electroencephalography was performed in some cases, based on each centre’s criteria and the patient’s characteristics.</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Results</span><p id="par0050" class="elsevierStylePara elsevierViewall">During the study period, we recruited a total of 34 patients, with a mean age of 68.3 years (range, 27–89). Twenty-five patients (73.5%) were older than 60. Seventeen patients were women. Patients’ demographic and clinical data are summarised in <a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>.</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Clinical manifestations</span><p id="par0055" class="elsevierStylePara elsevierViewall">Several patients presented more than one symptom. Onset was acute in all cases except for one patient with meningeal carcinomatosis, who developed headache and progressive onset of focal neurological signs. The most frequent symptom was focal neurological deficit (n<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>21, 62%), with 10 patients (29%) manifesting repetitive stereotyped behaviours and 11 patients (33%) presenting established deficits. Eleven patients (33%) presented headache, with thunderclap headache in only 4 (12%). Three patients (9%) presented confusion, with one of these displaying symptoms resembling an episode of transient global amnesia. Three patients (9%) developed seizures as the initial symptom; these were generalised in 2 cases. Two patients (6%) reported non-specific visual alterations together with other symptoms. One patient displayed neck rigidity.</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Radiological findings</span><p id="par0060" class="elsevierStylePara elsevierViewall">Haemorrhage was identified in the CT scan in 28 cases (85%), and in the MRI study in the remaining patients. A brain MRI scan was performed in 30 patients (88%), and brain angiography in 12 patients (35%). Bleeding was mostly unilateral, with the most frequent locations being the parietal and frontal regions. Diffusion-weighted MRI sequences showed cortical hyperintensity in 10 patients (33% of all patients undergoing MRI), which was adjacent to the cSAH in most cases. Old haemorrhages were detected in 7 cases (23%), and superficial siderosis in another location was detected in 2 (7%). An intra- and extracranial vascular study using CT angiography, MRI angiography, or conventional angiography was performed in 30 cases (88%); this study revealed no aneurysm or arteriovenous malformation except in one patient, who presented a small aneurysm measuring 1.2<span class="elsevierStyleHsp" style=""></span>mm in diameter, located away from the bleeding site. Five patients presented carotid artery involvement ipsilateral to the bleeding (2 significant stenoses, 2 complete occlusions, and one intrastent thrombus). Multiple intracranial stenoses were detected in 2 patients; one patient presented ipsilateral middle cerebral artery occlusion.</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">Other studies</span><p id="par0065" class="elsevierStylePara elsevierViewall">Ten patients (29%) underwent electroencephalography studies, revealing epileptiform activity in only 3 cases. Fourteen patients underwent lumbar puncture. Cerebrospinal fluid analysis revealed no abnormalities. Xanthochromia was not detected in any case. We detected lymphocytic pleocytosis in 3 patients, a slightly increased protein level in 2, and oligoclonal bands in one. The cytological study detected malignant cells in one patient. We calculated the tau/Abeta42 ratio in 7 patients; results were pathological in 3.</p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0095">Aetiology</span><p id="par0070" class="elsevierStylePara elsevierViewall"><a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a> includes the causes of bleeding, which we were able to establish in 26 patients (76.5%).</p><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><p id="par0075" class="elsevierStylePara elsevierViewall">The most frequent diagnosis was CAA (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>), accounting for a total of 8 cases. Three patients were diagnosed during the one-year follow-up period: one due to recurrence of cSAH and presence of superficial siderosis on MRI, and the other 2 due to lobar haemorrhage.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0080" class="elsevierStylePara elsevierViewall">The second most frequent cause was ischaemic stroke (n<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>5): 2 cardioembolic strokes, one atherothrombotic infarction, one stroke secondary to carotid artery occlusion, and one case of carotid stent thrombosis (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>).</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0085" class="elsevierStylePara elsevierViewall">The third most frequent cause was vasculitis (n<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>4). Three cases were secondary (Sjögren syndrome, Churg-Strauss syndrome, neurosyphilis), with the fourth patient presenting primary angiitis of the central nervous system. The remaining aetiologies included: PRES (n<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>2), CVT (n<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>2), RCVS (n<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>2), carotid artery occlusion with no associated infarction (n<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>1), Marfan syndome (n<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>1), and meningeal carcinomatosis (n<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>1).</p></span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0100">Progression</span><p id="par0090" class="elsevierStylePara elsevierViewall">One patient diagnosed with CVT and prostate cancer died during admission due to a massive cerebral haematoma. Two other patients died during the follow-up period, one due to meningeal carcinomatosis originated by cSAH, and another who was diagnosed with CAA due to an unrelated cause. Overall mortality amounted to 9% (<a class="elsevierStyleCrossRef" href="#tbl0015">Table 3</a>).</p><elsevierMultimedia ident="tbl0015"></elsevierMultimedia><p id="par0095" class="elsevierStylePara elsevierViewall">We were able to follow up 32 of 33 patients (97%). One-year outcomes were favourable in 24 patients (73%) and unfavourable in 9 (27%).</p><p id="par0100" class="elsevierStylePara elsevierViewall">Twelve percent of patients presented rebleeding within one year of follow-up (3 lobar haematomas and one new cSAH). Three patients developed dementia.</p></span></span><span id="sec0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0105">Discussion</span><p id="par0105" class="elsevierStylePara elsevierViewall">In addition to presenting one of the largest series of patients with cSAH (34 cases), this study is to our knowledge the first prognostic study with prospective follow-up and data progression at one year.</p><p id="par0110" class="elsevierStylePara elsevierViewall">Our results show several differences between cSAH and aneurysmal SAH. Firstly, the most frequent initial manifestation was not headache but focal neurological signs, which manifested in approximately two-thirds of patients in our series. Seventeen patients (50%) presented recurrent, stereotyped (especially paresthesia affecting one side of the body), short-lasting transient neurological deficits; in these cases, CAA was the most frequent underlying cause. One-third of patients presented headache as the initial symptom, with thunderclap headache in some cases. Neck rigidity, a typical sign of aneurysmal SAH, was exceptional. We should also underscore that there was no case of bleeding due to aneurysmal rupture, that patients had no family history of SAH or intracranial aneurysm, and that the percentage of smokers and alcohol users (well-established risk factors for aneurysmal SAH) was low.</p><p id="par0115" class="elsevierStylePara elsevierViewall">Our findings show that cSAH may be due to various causes, going beyond other authors’ dichotomy of RCVS in young patients and CAA in elderly patients.<a class="elsevierStyleCrossRefs" href="#bib0095"><span class="elsevierStyleSup">19,23</span></a> The 3 most frequently diagnosed causes were CAA, ischaemic stroke, and vasculitis.</p><p id="par0120" class="elsevierStylePara elsevierViewall">A possible explanation for CAA being the most frequent cause of cSAH is that most of patients were older than 60 years, as is reported in previous studies.<a class="elsevierStyleCrossRefs" href="#bib0100"><span class="elsevierStyleSup">20,22,26</span></a> Almost all patients presented recurrent, stereotyped transient neurological deficits, also known as amyloid spells. It has been suggested that cSAH may precede the appearance of a lobar haematoma by several weeks.<a class="elsevierStyleCrossRefs" href="#bib0015"><span class="elsevierStyleSup">3,4,27</span></a> In fact, 4 of our patients presented rebleeding in the months following admission. Therefore, antithrombotics should be prescribed with caution. When initial diagnosis is uncertain, a deferred brain MRI study may help to establish a diagnosis of CAA if rebleeding or superficial siderosis are observed.<a class="elsevierStyleCrossRefs" href="#bib0020"><span class="elsevierStyleSup">4,5,24</span></a></p><p id="par0125" class="elsevierStylePara elsevierViewall">Regarding ischaemic stroke, a retrospective review of almost 5000 patients with acute stroke or transient ischaemic attack showed low incidence of cSAH (8 cases; 0.14%).<a class="elsevierStyleCrossRef" href="#bib0065"><span class="elsevierStyleSup">13</span></a> We believe copresence of CAA to be the most probable underlying mechanism. However, another study reports an unusually high incidence of cSAH associated with brain ischaemia among patients with heart disease and implanted left ventricular assist devices.<a class="elsevierStyleCrossRef" href="#bib0140"><span class="elsevierStyleSup">28</span></a> It should be noted that the mean age in that study was 39 years, making CAA highly improbable. In these cases, the most probable mechanism is haemorrhagic transformation of a cardioembolic stroke, which is also favoured by the fact that many patients were receiving anticoagulants. Some cases have been reported of cSAH associated with carotid artery occlusion or stenosis. The mechanism could again be haemorrhagic transformation of a small ischaemic stroke or rupture of fragile collateral vessels, even in the absence of infarction,<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">14</span></a> as occurred in one of our patients. Carotid artery stenosis may be underdiagnosed, as the extracranial carotid artery is frequently not explored.</p><p id="par0130" class="elsevierStylePara elsevierViewall">Cortical SAH is a frequent manifestation of primary cerebral vasculitis or vasculitis secondary to autoimmune systemic diseases.<a class="elsevierStyleCrossRefs" href="#bib0035"><span class="elsevierStyleSup">7,29,30</span></a> A study by Boulouis et al.,<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">8</span></a> including 60 patients diagnosed with primary angiitis of the central nervous system, reported vasculitis in 26% of cases. In our series, vasculitis was suspected due to the patient’s history in 3 of the 4 cases; diagnosis was supported by the presence of multiple arterial stenoses in the vascular study. Meningeal enhancement in the MRI study helped to establish a differential diagnosis with RCVS. Changes in the cerebrospinal fluid and response to immunosuppressant treatment supported diagnosis.</p><p id="par0135" class="elsevierStylePara elsevierViewall">It is important to identify the underlying cause of bleeding, not only to orient treatment but also to establish prognosis. Diagnostic yield increases with an extensive initial aetiological study and with follow-up of the patient. Brain MRI is the most useful complementary test. FLAIR sequences are more sensitive than head CT in identifying acute bleeding, whereas echo-gradient MRI helps to identify old haemorrhages, superficial siderosis, and cortical CVT.<a class="elsevierStyleCrossRefs" href="#bib0015"><span class="elsevierStyleSup">3,17,31,32</span></a> An intra- and extracranial vascular study should be performed in every patient. Cerebral angiography would be reserved for those cases in which diagnosis is not established after performing these studies, or in which vasculitis or RCVS is suspected.</p><p id="par0140" class="elsevierStylePara elsevierViewall">It was possible to establish a diagnosis during admission in 23 patients (68%). We should highlight the importance of follow-up after discharge, which enabled us to increase this number to 26 (76.5%).</p><p id="par0145" class="elsevierStylePara elsevierViewall">Prognosis of patients with cSAH differs between series. Studies reporting good progression usually include younger patients diagnosed with PRES, CVT, or RCVS.<a class="elsevierStyleCrossRefs" href="#bib0045"><span class="elsevierStyleSup">9,15,16,18</span></a> Other studies report poor progression, associated especially with age.<a class="elsevierStyleCrossRefs" href="#bib0020"><span class="elsevierStyleSup">4,19,22,26</span></a><span class="elsevierStyleSup">,</span><a class="elsevierStyleCrossRef" href="#bib0165"><span class="elsevierStyleSup">33</span></a> Only the study by Martínez-Lizana et al.<span class="elsevierStyleSup">4</span> included patients diagnosed with CAA and ambispective follow-up. Our study is the first to include prospective follow-up, which was possible in more than 95% of cases. All patients with a modified Rankin Scale score >2 at one year (27% of patients) were older than 65. Furthermore, both cognitive impairment and all episodes of rebleeding were recorded in patients diagnosed with CAA. Therefore, prognosis will depend on age and aetiology, and is poorer in older patients with CAA.</p><p id="par0150" class="elsevierStylePara elsevierViewall">Our study has several limitations. Not all the available diagnostic tests were performed on all patients, especially very elderly patients with a very poor situation at baseline. Specifically, brain MRI and extracranial carotid artery exploration were not performed in all cases. Cerebral angiography was not performed in all cases of uncertain diagnosis.</p><p id="par0155" class="elsevierStylePara elsevierViewall">In conclusion, cSAH is a rare cerebrovascular disease with numerous possible aetiologies. In our series, the most frequent causes were amyloid angiopathy, ischaemic stroke, and vasculitis. Prognosis is poorer than in other non-aneurysmal SAHs. In elderly patients, risk of intracranial haemorrhage and cognitive impairment is greater due to the frequent association with CAA.</p></span><span id="sec0050" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0110">Conflicts of interest</span><p id="par0160" class="elsevierStylePara elsevierViewall">This study has received no funding of any kind. The authors have no conflicts of interest to declare.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:10 [ 0 => array:3 [ "identificador" => "xres1482258" "titulo" => "Abstract" "secciones" => array:4 [ 0 => array:2 [ "identificador" => "abst0005" "titulo" => "Introduction" ] 1 => array:2 [ "identificador" => "abst0010" "titulo" => "Methods" ] 2 => array:2 [ "identificador" => "abst0015" "titulo" => "Results" ] 3 => array:2 [ "identificador" => "abst0020" "titulo" => "Conclusions" ] ] ] 1 => array:2 [ "identificador" => "xpalclavsec1349659" "titulo" => "Keywords" ] 2 => array:3 [ "identificador" => "xres1482257" "titulo" => "Resumen" "secciones" => array:4 [ 0 => array:2 [ "identificador" => "abst0025" "titulo" => "Introducción" ] 1 => array:2 [ "identificador" => "abst0030" "titulo" => "Métodos" ] 2 => array:2 [ "identificador" => "abst0035" "titulo" => "Resultados" ] 3 => array:2 [ "identificador" => "abst0040" "titulo" => "Conclusiones" ] ] ] 3 => array:2 [ "identificador" => "xpalclavsec1349658" "titulo" => "Palabras clave" ] 4 => array:2 [ "identificador" => "sec0005" "titulo" => "Introduction" ] 5 => array:2 [ "identificador" => "sec0010" "titulo" => "Patients and methods" ] 6 => array:3 [ "identificador" => "sec0015" "titulo" => "Results" "secciones" => array:5 [ 0 => array:2 [ "identificador" => "sec0020" "titulo" => "Clinical manifestations" ] 1 => array:2 [ "identificador" => "sec0025" "titulo" => "Radiological findings" ] 2 => array:2 [ "identificador" => "sec0030" "titulo" => "Other studies" ] 3 => array:2 [ "identificador" => "sec0035" "titulo" => "Aetiology" ] 4 => array:2 [ "identificador" => "sec0040" "titulo" => "Progression" ] ] ] 7 => array:2 [ "identificador" => "sec0045" "titulo" => "Discussion" ] 8 => array:2 [ "identificador" => "sec0050" "titulo" => "Conflicts of interest" ] 9 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2017-07-20" "fechaAceptado" => "2017-12-16" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec1349659" "palabras" => array:6 [ 0 => "Cortical subarachnoid haemorrhage" 1 => "Non-traumatic subarachnoid haemorrhage" 2 => "Cerebral amyloid angiopathy" 3 => "Prognosis" 4 => "Ischaemic stroke" 5 => "Aetiology" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec1349658" "palabras" => array:6 [ 0 => "Hemorragia subaracnoidea cortical" 1 => "Hemorragia subaracnoidea atraumática" 2 => "Angiopatía amiloide" 3 => "Pronóstico" 4 => "Ictus isquémico" 5 => "Etiología" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:3 [ "titulo" => "Abstract" "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Introduction</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Cortical subarachnoid haemorrhage (cSAH) has multiple aetiologies. No prospective study has reported the long-term progression of the condition. The objective of this study is to describe the clinical and aetiological characteristics of patients with cSAH and to gain insight into prognosis.</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Methods</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">We performed a prospective, observational, multi-centre study. Data on clinical and radiological variables were collected; during a one-year follow-up period, we recorded data on mortality, dependence, rebleeding, and the appearance of dementia.</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Results</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">The study included 34 patients (mean age, 68.3 years; range, 27–89). The most frequent symptoms were headache and focal neurological deficits, which were frequently transient and recurrent. CT scans returned pathological findings in 28 patients (85%). Brain MRI scans were performed in 30 patients (88%), revealing acute ischaemia in 10 (29%), old haemorrhage in 7 (21%), and superficial siderosis in 2 (6%). Aetiology was identified in 26 patients (76.5%): causes were cerebral amyloid angiopathy in 8, ischaemic stroke in 5, vasculitis in 4, reversible posterior encephalopathy in 2, venous thrombosis in 2, reversible cerebral vasoconstriction syndrome in 2, carotid occlusion in 1, Marfan syndrome in 1, and meningeal carcinomatosis in 1. Three patients died during follow-up (2 due to causes related to the cause of cSAH). Three patients developed dementia, 3 had lobar haemorrhages, and one had a second cSAH.</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclusions</span><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">The most frequent causes of cSAH in our series were cerebral amyloid angiopathy, ischaemic stroke, and vasculitis. This type of haemorrhage has a worse prognosis than other non-aneurysmal cSAH. There are numerous possible causes, and prognosis depends on the aetiology. In elderly patients, intracranial haemorrhage is frequently associated with cognitive impairment.</p></span>" "secciones" => array:4 [ 0 => array:2 [ "identificador" => "abst0005" "titulo" => "Introduction" ] 1 => array:2 [ "identificador" => "abst0010" "titulo" => "Methods" ] 2 => array:2 [ "identificador" => "abst0015" "titulo" => "Results" ] 3 => array:2 [ "identificador" => "abst0020" "titulo" => "Conclusions" ] ] ] "es" => array:3 [ "titulo" => "Resumen" "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Introducción</span><p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Las hemorragias subaracnoideas corticales (HSAc) tienen numerosas etiologías. No hay estudios prospectivos que indiquen su evolución a largo plazo. El objetivo de este trabajo es describir las características clínicas y etiológicas de los pacientes con HSAc y conocer su pronóstico.</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Métodos</span><p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">Estudio observacional, prospectivo y multicéntrico. Se recogieron variables clínicas y radiológicas, y se siguió la evolución al año, observando la mortalidad, dependencia, tasa de resangrado y aparición de demencia.</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Resultados</span><p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">Se incluyeron 34 pacientes (edad media 68.3 años, rango 27–89). Los síntomas más frecuentes fueron el déficit neurológico focal, con frecuencia transitorio y de repetición, y la cefalea. El TAC fue patológico en 28 pacientes (85%). Se realizó RM cerebral en 30 pacientes (88%), con isquemia aguda en 10 (29%), sangrados antiguos en 7 (21%) y siderosis superficial en otros 2 (6%). Se encontró etiología en 26 pacientes (76.5%): angiopatía amiloide (n<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>8), ictus isquémico (n<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>5), vasculitis (n<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>4), encefalopatía posterior reversible (n<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>2), trombosis venosa (n<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>2), síndrome de vasoconstricción cerebral reversible (n<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>2), oclusión carotidea (n<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>1), síndrome de Marfan (n<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>1) y carcinomatosis meníngea (n<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>1). Durante el seguimiento fallecieron tres pacientes (en dos de ellos relacionado con la causa de la HSAc). Tres pacientes desarrollaron una demencia, tres presentaron un hematoma lobar y otro una nueva HSAc.</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclusiones</span><p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">En nuestra serie las causas más frecuentes de HSAc fueron la angiopatía amiloide, el ictus isquémico y la vasculitis. La HSAc tiene peor pronóstico que otras HSA no aneurismáticas. Puede tener numerosas causas y su pronóstico depende de la etiología subyacente. En el anciano existe una frecuente asociación con hemorragia intracraneal y deterioro cognitivo.</p></span>" "secciones" => array:4 [ 0 => array:2 [ "identificador" => "abst0025" "titulo" => "Introducción" ] 1 => array:2 [ "identificador" => "abst0030" "titulo" => "Métodos" ] 2 => array:2 [ "identificador" => "abst0035" "titulo" => "Resultados" ] 3 => array:2 [ "identificador" => "abst0040" "titulo" => "Conclusiones" ] ] ] ] "NotaPie" => array:2 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Galiano Blancart RF, et al. Pronóstico al año de la hemorragia subaracnoidea cortical no traumática: serie prospectiva de 34 pacientes. Neurología. 2021;36:215–221.</p>" ] 1 => array:2 [ "etiqueta" => "☆☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0010">This study was presented at the 68th Annual Meeting of the Spanish Society of Neurology.</p>" ] ] "multimedia" => array:5 [ 0 => array:8 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1087 "Ancho" => 2000 "Tamanyo" => 134063 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0245" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Eighty-year-old patient with CAA. A) Head CT scan showing hyperintensity in a sulcus of the right frontal convexity. B) Echo-gradient MRI sequence showing extensive, bilateral superficial siderosis.</p>" ] ] 1 => array:8 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 825 "Ancho" => 2000 "Tamanyo" => 132383 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0250" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Eighty-two-year-old patient presenting sudden-onset loss of strength and sensitivity in the left arm 6 days after implantation of a left carotid stent. A) Head CT scan showing cSAH of the left convexity. B) Diffusion-weighted MRI scan revealing acute infarction adjacent to the bleeding. C) MRI-angiography showing stent thrombosis (arrow).</p>" ] ] 2 => array:8 [ "identificador" => "tbl0005" "etiqueta" => "Table 1" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0255" "detalle" => "Table " "rol" => "short" ] ] "tabla" => array:1 [ "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black"> \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">n (%) \t\t\t\t\t\t\n \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Age (years) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">68.3 (74% older than 60) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Sex (men) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">17 (50) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Arterial hypertension \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">21 (62) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Dyslipidaemia \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">10 (29) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Diabetes mellitus \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">5 (15) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Atrial fibrillation \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2 (6) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Cognitive impairment \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">4 (12) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Prior ischaemic stroke \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">5 (15) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Smoker or former smoker \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">10 (30) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Alcohol use \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2 (6) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Drug use \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2 (6) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Anti-platelet agents \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">6 (18) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Anticoagulants \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">4 (12) \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab2550964.png" ] ] ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Patient characteristics.</p>" ] ] 3 => array:8 [ "identificador" => "tbl0010" "etiqueta" => "Table 2" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0260" "detalle" => "Table " "rol" => "short" ] ] "tabla" => array:2 [ "leyenda" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">cSAH: cortical subarachnoid haemorrhage; CVT: cerebral venous thrombosis; PRES: posterior reversible encephalopathy syndrome; RCVS: reversible cerebral vasoconstriction syndrome.</p>" "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black"> \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">n (%) \t\t\t\t\t\t\n \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><span class="elsevierStyleItalic">Amyloid angiopathy</span> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">8 (23.5%) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><span class="elsevierStyleItalic">Ischaemic stroke</span> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">5 (15%) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><span class="elsevierStyleItalic">Vasculitis</span> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">4 (12%) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " colspan="2" align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><span class="elsevierStyleItalic">Miscellaneous</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>PRES \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2 (6%) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>CVT \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2 (6%) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>RCVS \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2 (6%) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Carotid artery occlusion without infarct \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1 (3%) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Marfan syndrome \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1 (3%) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Meningeal carcinomatosis \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1 (3%) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><span class="elsevierStyleItalic">Diagnosis not established</span> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">8 (23.5%) \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab2550966.png" ] ] ] ] "descripcion" => array:1 [ "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Aetiologies of cSAH.</p>" ] ] 4 => array:8 [ "identificador" => "tbl0015" "etiqueta" => "Table 3" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0265" "detalle" => "Table " "rol" => "short" ] ] "tabla" => array:1 [ "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black"> \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">n (%) \t\t\t\t\t\t\n \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Death \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">3 (9) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Rebleeding \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">4 (12) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Dementia \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">3 (9) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Modified Rankin Scale score >2 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">9 (27) \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab2550965.png" ] ] ] ] "descripcion" => array:1 [ "en" => "<p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">One-year progression of 33 patients (97% of all patients in the series).</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:33 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Subarachnoid haemorrhage: diagnosis, causes and management" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "J. Van Gijn" 1 => "G.J. Rinkel" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1093/brain/124.2.249" "Revista" => array:6 [ "tituloSerie" => "Brain" "fecha" => "2001" "volumen" => "124" "paginaInicial" => "249" "paginaFinal" => "278" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11157554" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cerebral convexity subarachnoid hemorrhage: various causes and role of diagnostic imaging" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "R. Mangla" 1 => "D. Drumsta" 2 => "J. Alamst" 3 => "M. Mangla" 4 => "M. Potchen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Emerg Radiol" "fecha" => "2015" "volumen" => "22" "paginaInicial" => "181" "paginaFinal" => "195" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cortical superficial siderosis: detection and clinical significance in cerebral amyloid angiopathy and related conditions" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A. Charidimou" 1 => "J. Linn" 2 => "M.W. Vernooij" 3 => "C. Opherk" 4 => "S. Akoudad" 5 => "J.C. Baron" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1093/brain/awv162" "Revista" => array:6 [ "tituloSerie" => "Brain" "fecha" => "2015" "volumen" => "138" "paginaInicial" => "2126" "paginaFinal" => "2139" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26115675" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cerebral amyloid angiopathy-related atraumatic convexal subarachnoid hemorrhage: an ARIA before the tsunami" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "E. Martínez-Lizana" 1 => "M. Carmona-Iragui" 2 => "D. Alcolea" 3 => "M. Gómez-Choco" 4 => "E. Vilaplana" 5 => "M.B. Sánchez-Saudinós" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J of Cereb Blood Flow Metab" "fecha" => "2015" "volumen" => "35" "paginaInicial" => "710" "paginaFinal" => "717" ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Acute convexity subarachnoid hemorrhage related to cerebral amyloid angiopathy: clinicoradiological features and outcome" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "L. Calviere" 1 => "V. Cuvinciuc" 2 => "N. Raposo" 3 => "A. Faury" 4 => "C. Cognard" 5 => "V. Larrue" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jstrokecerebrovasdis.2015.11.010" "Revista" => array:6 [ "tituloSerie" => "J Stroke Cerebrovasc Dis" "fecha" => "2016" "volumen" => "25" "paginaInicial" => "1009" "paginaFinal" => "1016" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26923093" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Spontaneous convexity subarachnoid haemorrhage: Clinical series of 3 patients with associated cerebral amyloid angiopathy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "D.A. García Estévez" 1 => "R.M. García-Dorrego" 2 => "B. Nieto-Baltar" 3 => "M. Marey-Garrido" 4 => "T. Hierro-Torner" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Neurologia" "fecha" => "2017" "volumen" => "32" "paginaInicial" => "213" "paginaFinal" => "218" ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0035" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Isolated angiitis of the CNS presenting as subarachnoid haemorrhage" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "R. Kumar" 1 => "E.F. Wijdicks" 2 => "R.D. Brown Jr" 3 => "J.E. Parisi" 4 => "C.A. Hammond" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Neurol Neurosurg Psychiatry" "fecha" => "1997" "volumen" => "62" "paginaInicial" => "649" "paginaFinal" => "651" ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0040" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Primary angiitis of the central nervous system: magnetic resonance imaging spectrum of parenchymal, meningeal, and vascular lesions at baseline" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "G. Boulouis" 1 => "H. de Boysson" 2 => "M. Zuber" 3 => "L. Guillevin" 4 => "E. Meary" 5 => "V. Costalat" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Stroke" "fecha" => "2017" "volumen" => "48" "paginaInicial" => "1248" "paginaFinal" => "1255" ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0045" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Reversible cerebral vasoconstriction syndromes: analysis of 139 cases" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A.B. Singhal" 1 => "R.A. Hajj-Ali" 2 => "M.A. Topcuoglu" 3 => "J. Fok" 4 => "J. Bena" 5 => "D. Yang" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1001/archneurol.2011.68" "Revista" => array:6 [ "tituloSerie" => "Arch Neurol" "fecha" => "2011" "volumen" => "68" "paginaInicial" => "1005" "paginaFinal" => "1012" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21482916" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib0050" "etiqueta" => "10" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Hemorrhage in posterior reversible encephalopathy syndrome: imaging and clinical features" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "H.M. Hefzy" 1 => "W.S. Bartynski" 2 => "J.F. Boardman" 3 => "D. Lacomis" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.3174/ajnr.A1588" "Revista" => array:6 [ "tituloSerie" => "AJNR Am J Neuroradiol" "fecha" => "2009" "volumen" => "30" "paginaInicial" => "1371" "paginaFinal" => "1379" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19386731" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib0055" "etiqueta" => "11" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intracranial dural arteriovenous fistulas: classification, imaging findings, and treatment" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "D. Gandhi" 1 => "J. Chen" 2 => "M. Pearl" 3 => "J. Huang" 4 => "J.J. Gemmete" 5 => "S. Kathuria" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.3174/ajnr.A2798" "Revista" => array:6 [ "tituloSerie" => "AJNR Am J Neuroradiol" "fecha" => "2012" "volumen" => "33" "paginaInicial" => "1007" "paginaFinal" => "1013" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22241393" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib0060" "etiqueta" => "12" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Subarachnoid haemorrhage associated with infectious endocarditis: case report and literature review" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "F.E. Chukwudelunzu" 1 => "R.D. Brown Jr" 2 => "E.F. Wijdicks" 3 => "J.M. Steckelberg" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Eur J Neurol" "fecha" => "2002" "volumen" => "9" "paginaInicial" => "423" "paginaFinal" => "427" ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib0065" "etiqueta" => "13" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Nontraumatic convexal subarachnoid hemorrhage concomitant with acute ischemic stroke" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "M. Nakajima" 1 => "Y. Inatomi" 2 => "T. Yonehara" 3 => "T. Hirano" 4 => "Y. Ando" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jstrokecerebrovasdis.2013.12.046" "Revista" => array:6 [ "tituloSerie" => "J Stroke Cerebrovasc Dis" "fecha" => "2014" "volumen" => "23" "paginaInicial" => "1564" "paginaFinal" => "1570" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24630829" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib0070" "etiqueta" => "14" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Convexity subarachnoid haemorrhage associated with bilateral internal carotid artery stenoses" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "T.J. Kleinig" 1 => "T.E. Kimber" 2 => "P.D. Thompson" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1007/s00415-009-0106-0" "Revista" => array:6 [ "tituloSerie" => "J Neurol" "fecha" => "2009" "volumen" => "256" "paginaInicial" => "669" "paginaFinal" => "671" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19401805" "web" => "Medline" ] ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib0075" "etiqueta" => "15" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Localized convexity subarachnoid haemorrhage-a sign of early cerebral venous sinus thrombosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "S. Panda" 1 => "D.K. Prashantha" 2 => "S.R. Shankar" 3 => "D. Nagaraja" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1468-1331.2010.03001.x" "Revista" => array:6 [ "tituloSerie" => "Eur J Neurol" "fecha" => "2010" "volumen" => "17" "paginaInicial" => "1249" "paginaFinal" => "1258" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20402745" "web" => "Medline" ] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib0080" "etiqueta" => "16" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cortical subarachnoid hemorrhage caused by cerebral venous thrombosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "S. Oda" 1 => "M. Shimoda" 2 => "K. Hoshikawa" 3 => "T. Osada" 4 => "M. Yoshiyama" 5 => "M. Matsumae" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Neurol Med Chir (Tokyo)" "fecha" => "2011" "volumen" => "51" "paginaInicial" => "30" "paginaFinal" => "36" ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib0085" "etiqueta" => "17" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Radiological findings in cerebral venous thrombosis presenting as subarachnoid hemorrhage: a series of 22 cases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "M. Boukobza" 1 => "I. Crassard" 2 => "M.G. Bousser" 3 => "H. Chabriat" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1007/s00234-015-1594-5" "Revista" => array:6 [ "tituloSerie" => "Neuroradiology" "fecha" => "2016" "volumen" => "58" "paginaInicial" => "11" "paginaFinal" => "16" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26376804" "web" => "Medline" ] ] ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib0090" "etiqueta" => "18" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Spontaneous isolated convexity subarachnoid hemorrhage: presentation, radiological findings, differential diagnosis, and clinical course" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "D. Refai" 1 => "J.A. Botros" 2 => "R.G. Strom" 3 => "C.P. Derdeyn" 4 => "A. Sharma" 5 => "G.J. Zipfel" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.3171/JNS.2008.109.12.1034" "Revista" => array:6 [ "tituloSerie" => "J Neurosurg" "fecha" => "2008" "volumen" => "109" "paginaInicial" => "1034" "paginaFinal" => "1041" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19035716" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib0095" "etiqueta" => "19" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Atraumatic convexal subarachnoid hemorrhage: clinical presentation, imaging patterns, and etiologies" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "S. Kumar" 1 => "R.P. Goddeau Jr" 2 => "M.H. Selim" 3 => "A. Thomas" 4 => "G. Schlaug" 5 => "A. Alhazzani" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1212/WNL.0b013e3181d55efa" "Revista" => array:6 [ "tituloSerie" => "Neurology" "fecha" => "2010" "volumen" => "74" "paginaInicial" => "893" "paginaFinal" => "899" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20231664" "web" => "Medline" ] ] ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib0100" "etiqueta" => "20" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Focal convexal subarachnoid hemorrhage: clinical presentation, imaging patterns and etiologic findings in 23 patients" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "J. Mas" 1 => "S. Bouly" 2 => "I. Mourand" 3 => "D. Renard" 4 => "N. de Champfleur" 5 => "P. Labauge" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Rev Neurol (Paris)" "fecha" => "2013" "volumen" => "169" "paginaInicial" => "59" "paginaFinal" => "66" ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib0105" "etiqueta" => "21" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical associations and causes of convexity subarachnoid hemorrhage" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "A. Khurram" 1 => "T. Kleinig" 2 => "J. Leyden" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1161/STROKEAHA.113.004298" "Revista" => array:6 [ "tituloSerie" => "Stroke" "fecha" => "2014" "volumen" => "45" "paginaInicial" => "1151" "paginaFinal" => "1153" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24496391" "web" => "Medline" ] ] ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib0110" "etiqueta" => "22" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Nontraumatic convexity subarachnoid hemorrhage: different etiologies and outcomes" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "R. Geraldes" 1 => "P.R. Sousa" 2 => "A.C. Fonseca" 3 => "F. Falcão" 4 => "P. Canhão" 5 => "T. Pinho e Melo" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jstrokecerebrovasdis.2013.08.005" "Revista" => array:7 [ "tituloSerie" => "J Stroke Cerebrovasc Dis" "fecha" => "2014" "volumen" => "23" "paginaInicial" => "e23" "paginaFinal" => "30" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24119619" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0140673612617280" "estado" => "S300" "issn" => "01406736" ] ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bib0115" "etiqueta" => "23" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Distinguishing clinical and radiological features of non-traumatic convexal subarachnoid hemorrhage" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "J. Graff-Radford" 1 => "J.E. Fugate" 2 => "J. Klaas" 3 => "K.D. Flemming" 4 => "R.D. Brown" 5 => "A.A. Rabinstein" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/ene.12926" "Revista" => array:6 [ "tituloSerie" => "Eur J Neurol" "fecha" => "2016" "volumen" => "23" "paginaInicial" => "839" "paginaFinal" => "846" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26910197" "web" => "Medline" ] ] ] ] ] ] ] ] 23 => array:3 [ "identificador" => "bib0120" "etiqueta" => "24" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Prevalence of superficial siderosis in patients with cerebral amyloid angiopathy" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J. Linn" 1 => "A. Halpin" 2 => "P. Demarael" 3 => "J. Ruhland" 4 => "A.D. Giese" 5 => "M. Dichgans" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1212/WNL.0b013e3181dad605" "Revista" => array:6 [ "tituloSerie" => "Neurology" "fecha" => "2010" "volumen" => "74" "paginaInicial" => "1346" "paginaFinal" => "1350" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20421578" "web" => "Medline" ] ] ] ] ] ] ] ] 24 => array:3 [ "identificador" => "bib0125" "etiqueta" => "25" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Narrative review: Reversible cerebral vasoconstriction syndromes" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "L.H. Calabrese" 1 => "D.W. Dodick" 2 => "T.J. Schwedt" 3 => "A.B. Singhal" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.7326/0003-4819-146-1-200701020-00007" "Revista" => array:6 [ "tituloSerie" => "Ann Intern Med" "fecha" => "2007" "volumen" => "146" "paginaInicial" => "34" "paginaFinal" => "44" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17200220" "web" => "Medline" ] ] ] ] ] ] ] ] 25 => array:3 [ "identificador" => "bib0130" "etiqueta" => "26" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical presentation, etiology, and long-term prognosis in patients with nontraumatic convexal subarachnoid hemorrhage" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "M. Beitzke" 1 => "T. Gattringer" 2 => "C. Enzinger" 3 => "G. Wagner" 4 => "K. Niederkorn" 5 => "F. Fazekas" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1161/STROKEAHA.111.621847" "Revista" => array:6 [ "tituloSerie" => "Stroke" "fecha" => "2011" "volumen" => "42" "paginaInicial" => "3055" "paginaFinal" => "3060" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21921284" "web" => "Medline" ] ] ] ] ] ] ] ] 26 => array:3 [ "identificador" => "bib0135" "etiqueta" => "27" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The hemorrhage caused by sporadic-type cerebral amyloid angiopathy occurs primarily in the cerebral sulci" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "S. Takeda" 1 => "K. Hinokuma" 2 => "K. Yamazaki" 3 => "K. Onda" 4 => "T. Miyakawa" 5 => "F. Ikuta" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Neuropathology" "fecha" => "2012" "volumen" => "32" "paginaInicial" => "38" "paginaFinal" => "43" ] ] ] ] ] ] 27 => array:3 [ "identificador" => "bib0140" "etiqueta" => "28" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Sulcus subarachnoid hemorrhage is a common stroke subtype in patients with implanted left ventricular assist devices" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M. Sakaguchi" 1 => "K. Kitagawa" 2 => "S. Okazaki" 3 => "D. Yoshioka" 4 => "Y. Sakata" 5 => "H. Mochizuki" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/ene.12712" "Revista" => array:6 [ "tituloSerie" => "Eur J Neurol" "fecha" => "2015" "volumen" => "22" "paginaInicial" => "1088" "paginaFinal" => "1093" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25855522" "web" => "Medline" ] ] ] ] ] ] ] ] 28 => array:3 [ "identificador" => "bib0145" "etiqueta" => "29" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Varicella-Zoster vasculitis presenting with intracranial hemorrhage" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "R. Jain" 1 => "J. Deveikis" 2 => "S. Hickenbottom" 3 => "S. Mukherji" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Neuroradiol" "fecha" => "2003" "volumen" => "24" "paginaInicial" => "971" "paginaFinal" => "974" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12748105" "web" => "Medline" ] ] ] ] ] ] ] ] 29 => array:3 [ "identificador" => "bib0150" "etiqueta" => "30" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Non-traumatic cortical subarachnoid haemorrhage: diagnostic work-up and aetiological background" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "C. Spitzer" 1 => "M. Mull" 2 => "V. Rohde" 3 => "C.M. Kosinski" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1007/s00234-005-1384-6" "Revista" => array:6 [ "tituloSerie" => "Neuroradiology" "fecha" => "2005" "volumen" => "47" "paginaInicial" => "525" "paginaFinal" => "531" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15971064" "web" => "Medline" ] ] ] ] ] ] ] ] 30 => array:3 [ "identificador" => "bib0155" "etiqueta" => "31" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Comparison of magnetic resonance imaging sequences with computed tomography to detect low-grade subarachnoid hemorrhage: Role of fluid-attenuated inversion recovery sequence" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A.J. da Rocha" 1 => "C.J. da Silva" 2 => "H.P. Gama" 3 => "C.E. Baccin" 4 => "F.T. Braga" 5 => "A. Cesare Fde" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/00004728-200603000-00025" "Revista" => array:6 [ "tituloSerie" => "J Comput Assist Tomogr" "fecha" => "2006" "volumen" => "30" "paginaInicial" => "295" "paginaFinal" => "303" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16628051" "web" => "Medline" ] ] ] ] ] ] ] ] 31 => array:3 [ "identificador" => "bib0160" "etiqueta" => "32" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Isolated acute nontraumatic cortical subarachnoid hemorrhage" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "V. Cuvinciuc" 1 => "A. Viguier" 2 => "L. Calviere" 3 => "N. Raposo" 4 => "V. Larrue" 5 => "C. Cognard" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.3174/ajnr.A1986" "Revista" => array:6 [ "tituloSerie" => "AJNR Am J Neuroradiol" "fecha" => "2010" "volumen" => "31" "paginaInicial" => "1355" "paginaFinal" => "1362" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20093311" "web" => "Medline" ] ] ] ] ] ] ] ] 32 => array:3 [ "identificador" => "bib0165" "etiqueta" => "33" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Focal cortical subarachnoid hemorrhage revealed by recurrent paresthesias: a clinico-radiological syndrome strongly associated with cerebral amyloid angiopathy" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M. Apoil" 1 => "J. Cogez" 2 => "L. Dubuc" 3 => "M. Bataille" 4 => "V. de la Sayette" 5 => "E. Touzé" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1159/000353676" "Revista" => array:6 [ "tituloSerie" => "Cerebrovasc Dis" "fecha" => "2013" "volumen" => "36" "paginaInicial" => "139" "paginaFinal" => "144" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24029731" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/21735808/0000003600000003/v1_202103190809/S217358081930135X/v1_202103190809/en/main.assets" "Apartado" => array:4 [ "identificador" => "9491" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Original Articles" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/21735808/0000003600000003/v1_202103190809/S217358081930135X/v1_202103190809/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S217358081930135X?idApp=UINPBA00004N" ]
Year/Month | Html | Total | |
---|---|---|---|
2024 November | 12 | 0 | 12 |
2024 October | 26 | 2 | 28 |
2024 September | 57 | 1 | 58 |
2024 August | 53 | 5 | 58 |
2024 July | 32 | 7 | 39 |
2024 June | 40 | 6 | 46 |
2024 May | 27 | 7 | 34 |
2024 April | 35 | 5 | 40 |
2024 March | 50 | 6 | 56 |
2024 February | 42 | 1 | 43 |
2024 January | 58 | 7 | 65 |
2023 December | 65 | 5 | 70 |
2023 November | 85 | 5 | 90 |
2023 October | 89 | 5 | 94 |
2023 September | 35 | 6 | 41 |
2023 August | 32 | 4 | 36 |
2023 July | 50 | 8 | 58 |
2023 June | 55 | 1 | 56 |
2023 May | 93 | 0 | 93 |
2023 April | 75 | 2 | 77 |
2023 March | 91 | 4 | 95 |
2023 February | 72 | 5 | 77 |
2023 January | 84 | 10 | 94 |
2022 December | 57 | 8 | 65 |
2022 November | 50 | 8 | 58 |
2022 October | 38 | 11 | 49 |
2022 September | 37 | 10 | 47 |
2022 August | 33 | 8 | 41 |
2022 July | 40 | 7 | 47 |
2022 June | 36 | 8 | 44 |
2022 May | 52 | 7 | 59 |
2022 April | 37 | 13 | 50 |
2022 March | 70 | 9 | 79 |
2022 February | 71 | 4 | 75 |
2022 January | 45 | 12 | 57 |
2021 December | 56 | 11 | 67 |
2021 November | 41 | 8 | 49 |
2021 October | 82 | 14 | 96 |
2021 September | 77 | 16 | 93 |
2021 August | 44 | 10 | 54 |
2021 July | 34 | 4 | 38 |
2021 June | 30 | 12 | 42 |
2021 May | 54 | 11 | 65 |
2021 April | 158 | 20 | 178 |
2021 March | 67 | 8 | 75 |
2021 February | 38 | 9 | 47 |
2021 January | 49 | 15 | 64 |
2020 December | 49 | 14 | 63 |
2020 November | 43 | 10 | 53 |
2020 October | 33 | 5 | 38 |
2020 September | 55 | 15 | 70 |
2020 August | 45 | 16 | 61 |
2020 July | 45 | 13 | 58 |
2020 June | 41 | 22 | 63 |
2020 May | 33 | 22 | 55 |
2020 April | 21 | 6 | 27 |
2020 March | 26 | 17 | 43 |
2020 February | 30 | 5 | 35 |
2020 January | 18 | 8 | 26 |
2019 December | 21 | 11 | 32 |
2019 November | 11 | 10 | 21 |