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Vol. 47. Issue 12.
Pages 541-547 (January 2004)
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Vol. 47. Issue 12.
Pages 541-547 (January 2004)
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Cáncer de mama subclínico y edad
Subclinical breast cancer and age
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5037
D. Rubioaa,
Corresponding author
rubiol@ya.com

Correspondencia: Ctra. Húmera 87, P-15 2.° A. 28223 Pozuelo de Alarcón. Madrid. España
, J. Muñozb, J.M. Rubioaa, P. de la Fuentec
a Servicio de Ginecología. Hospital Universitario Ramón y Cajal. Madrid
b Servicio de Radiodiagnóstico. Hospital Universitario Ramón y Cajal. Madrid
c Departamento de Obstetricia y Ginecología. Hospital Universitario 12 de Octubre. Madrid. España
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Resumen
Objetivo

Analizar retrospectivamente los carcinomas de mama subclínicos hallados en el grupo de estudio de 263 pacientes con lesiones radiológicas de mama no palpables.

Material y método

El grupo de estudio está compuesto por 88 pacientes diagnosticadas mediante mamografía de lesión sospechosa no palpable con resultado histológico de malignidad. En todas ellas se realizó marcaje con arpón de la lesión mediante técnica estereotáxica y biopsia diferida con comprobación radiológica intraoperatoria de la pieza.

Resultadoso

De las 263 mujeres con mamografía sospechosa, en 88 (33,5%) casos el diagnóstico anatomopatológico fue de cáncer. En el grupo con edad inferior a 50 años la incidencia de cáncer fue de 25/98 (25%); en las edades comprendidas entre 50 y 65 años, de 46/113 (47%), y en las mayores de 65 años, de 17/34 (50%). Se diagnosticaron 27 carcinomas in situ, de los cuales 12 se presentaron en mujeres menores de 50 años y los 15 restantes en el grupo con edades comprendidas entre 50 y 65 años. La incidencia de carcinoma in situ en las mujeres jóvenes fue de 12/25 (48%), y en el grupo de edades comprendidas entre 50 y 65 años, de 15/47 (32%).

Conclusiones

Las imágenes mamográficas sospechosas corresponden en un elevado porcentaje de casos a lesiones malignas y la posibilidad es más elevada cuanto mayor es la edad de la mujer. Los cánceres no infiltrantes son más frecuentes en las mujeres jóvenes.

Palabras clave:
Mama
Cáncer
Subclínico
No palpable
Abstract
Objective

We retrospectively analyzed the subclinical breast carcinomas diagnosed in a group of 263 patients with radiologic non-palpable breast lesions.

Material and method

The study group was composed of 88 patients with a mammographic diagnosis of non-palpable breast lesion and malignant histologic results. In all patients preoperative hookwire-guided localization using the stereotaxic technique and deferred biopsy with intraoperative radiologic confirmation of the specimen were performed.

Results

There were 263 patients with suspicious mammography; of these, pathologic diagnosis was cancer in 88 (33.5%). Malignancy was detected in 25/98 (25%) patients in the group aged less than 50 years, in 46/113 (47%) in the group aged 50-65 years and in 17/34 (50%) in the group aged more than 65 years. In situ carcinoma was diagnosed in 27 patients of whom 12 were aged less than 50 years old and the remaining 15 were aged between 50 and 65 years old. The rate of in situ carcinoma in younger women was 12/25 (48%) and was 15 /47 (32%) in women in the 50-65 age group.

Conclusions

Suspicious mammographic findings are strongly associated with malignant lesions and the likelihood of malignancy increases with age. Non-infiltrating breast cancer is more frequent in young women.

Keywords:
Breast
Cancer
Subclinical
Non-palpable
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Bibliografía
[1.]
E.L. Elvecrog, M.C. Lechner, M.I. Nelson.
Nonpalpable breast lesions correlation of stereotaxic large-core needle biopsy and surgical biopsy results.
Radiology, 188 (1993), pp. 453-455
[2.]
J.E. Meyer.
Value of large-core biopsy of occult breast lesions.
AJR Am J Roentgenol, 158 (1992), pp. 991-992
[3.]
L.W. Basset, T.H. Liu, A.E. Giuliano, R.H. Gold.
The prevalence of carcinoma in palpable vs impalpable mammographically detected lesions.
Am J Radiol, 157 (1991), pp. 21-24
[4.]
S.H. Parker, J.D. Lovin, W.E. Jobe, B.J. Burke, K.D. Hopper, W.F. Yakes.
Nonpalpable breast lesions: Stereotactic automated largecore biopsies.
Radiology, 180 (1991), pp. 403-407
[5.]
G. Pérez Manga.
Clínica y diagnóstico en cáncer de mama.
pp. 35-58
[6.]
G.T. Schwartz, D.L. Carter, E.F. Conant, F.H. Gannon, G.C. Finkel, S.A. Feig.
Mammmographically detected breast cancer: non palpable is not synonym for inconsequential.
Cancer, 73 (1994), pp. 1660-1665
[7.]
S. Meterissian, B.D. Fornage, S.E. Singletary.
Clinically occult breast carcinoma: diagnostic approaches and role of axillary node dissection.
Ann Surg Oncol, 2 (1995), pp. 314-318
[8.]
P.B. Beaute, M. Thibodeau, G. Newstead.
Improving the yield of biopsy for nonpalpable lessions of the breast.
Surg Gynecol Obstet, 174 (1992), pp. 93-96
[9.]
B.R. McCreery, G. Frankl, D.B. Frost.
An analysis of the results of mammographically guided biopsies of the breast.
Surg Gynecol Obstet, 172 (1991), pp. 223-226
[10.]
D.M. Radford, D.T. Cromack, B.R. Troop, S.M. Keller, M.J. López.
Pathology and treatment of impalpable breast lessions.
Am J Surg, 164 (1992), pp. 427-431
[11.]
C. Ferratti, G. Coopmansde Yoldi, E. Biganzoli, S. Bergonzi, L. Mariani, G. Scaperrotta, et al.
Relationships between age, mammographic features and pathological tumour characteristics in non palpable breast cancer.
Br J Radiol, 73 (2000), pp. 698-705
[12.]
S.G. Orel, N. Kay, C. Reynolds, D.C. Sullivan.
BI-RADS categorization as a predictor of malignancy.
[13.]
P.H. Cottu, I. Cojean-Zelek, E. Bourstyn, A. De Roquancourt, J.M. Extra, F. Perret, et al.
Analyse rétrospective multivariee de la corrélation radio-anatomopathologique de lésions infracliniques du sein. Expérience de l’Hôpital Saint Louis.
Rev Med Interne, 21 (2000), pp. 337-343
[14.]
American College of Radiology.
Breast imaging reporting and data system (BI-RADS), 2nd,
[15.]
L.W. Basset.
Standardized reporting for mammography: BIRADS.
Breast J, 3 (1997), pp. 207-210
[16.]
C.J. D’Orsi.
American College of Radiology mammography lexicon: an initial attempt to standardize terminology.
Am J Radiol, 166 (1996), pp. 779-780
[17.]
G. Le Bouedec, P. Kuffman, J.M. Pingeon, C. Pomel, J. Dauplat.
Clinically occult invasive breast cancer. A series of 163 cases.
Ann Chir, 48 (1994), pp. 607-612
[18.]
S. Ciatto, M.R. Del Turco, R. Bonardi, L. Cataliotti, V. Distante, G. Cardona, et al.
Non palpable lesions of the breast detected by mammography: review of 1182 consecutive histologically confirmed cases.
Eur J Cancer, 30 (1994), pp. 40-44
[19.]
D. Cyrlak.
Induced cost of low cost screening mammography.
Radiology, 168 (1988), pp. 661-663
[20.]
S.H. Parker, J.D. Lovin, W.E. Jobe.
Stereotactic breast biopsy with a biopsy gun.
Radiology, 176 (1990), pp. 741-747
[21.]
J.E. Meyer, S.C. Lester, T.H. Frenna, F.V. White.
Occult breast calcifications sampled with core biopsy: confirmation with radiography of the specimen.
Radiology, 188 (1993), pp. 581-582
[22.]
G.J. Bowers, J.B. Getz, R.H. Roettger, C.E. Gaines, D.E. Beck.
Nonpalpable breast lesions: association of mammographic abnormalities with diagnosis after needle-directed biopsy.
South Med J, 87 (1993), pp. 748-752
[23.]
M. Meunier, M. Le Gal, J. Klijanierko, P. Vield, S. Nevenschivande, J.C. Duran, et al.
Non-palpable breast lesions: stereotaxic fine-needle aspiration. J.
Radiol, 7615 (1995), pp. 259-262
[24.]
R.L. Elliot, A.E. Haynes, J.A. Boloin, E.M. Boagin, J.F. Hedd.
Stereotaxic needle localization and biopsy of occult breast lesions: First year experience.
Am J Surg, 58 (1992), pp. 126-131
[25.]
S. Meterissian, B.D. Fornage, S.E. Singletary.
Clinically occult breast carcinoma: diagnostic approaches end role of the axilary node dissection.
Ann Surg Oncol, 2 (1995), pp. 314-318
[26.]
J. Schneider.
¿Cuál es el cáncer de mama de buen pronóstico?.
Prog Obstet Ginecol, 40 (1997), pp. 32-39
[27.]
B. Cady, M.D. Stone, J.G. Schuler, R. Thakur, M.A. Wanner, P.T. Lanvin.
The new era in breast cancer. Invasion, size and nodel involvement dramatically decreasing as a result of mammographic screening.
Arch Surg, 131 (1996), pp. 301-309
[28.]
R. Holland, J.H.C.L. Henddriks, A.L.M. Verbeck, M. Mravunac, M.A.N.S. Schuhrn, J.M. Tekhoven.
Extend, distribution and mammographic histological correlations of breast ductal carcinoma in situ.
Lancet, 325 (1992), pp. 519-522
[29.]
G. Hermann, C. Janus, I.S. Schwartz, A. Papatestas, D.G. Hermann, J.G. Rabinowitz.
Occult malignant breast lesions in 114 patients: relationship to age and presence of microcacifications.
Radiology, 169 (1988), pp. 321-324
Copyright © 2004. Sociedad Española de Ginecología y Obstetricia
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