Colposcopia digital en la neoplasia cervical intraepitelial. Correlación histológica y utilidad clínica

Article information

Resumen

Objetivo

Determinar, en la neoplasia cervical intraepitelial (CIN), la correlación histológica de la información morfométrica obtenida mediante un sistema original de colposcopia digital, y establecer sus posibles aplicaciones clínicas

Métodos

En 101 pacientes con colposcopia valorable se midió el área de la zona de transformación y de las lesiones colposcópicas. En 62 casos, en los que se practicó exéresis de la lesión con asa, estos datos se correlacionaron con la extensión de las lesiones histológicas

Resultados

A mayor grado histológico las lesiones cervicales incrementan significativamente su tamaño colposcópico (CIN-I, CIN-II, CIN-III: 90mm2, 134mm2, 265mm2, respectivamente) y ocupan una disposición más central en el cérvix. Existe una muy buena correlación, cercana al 85%, con el tamaño medido mediante morfometría histológica

Conclusiones

El tamaño de la lesión colposcópica de la CIN es un buen indicador del verdadero tamaño lesional. Estos resultados abren una nueva perspectiva en la conducta a seguir en las lesiones de bajo grado, al ofrecer un método objetivo y fiable para controlar su evolución

Palabras clave:

Colposcopia

Análisis de imagen

CIN

Morfometría

Historia natural

Summary

Objective

To determine the histological correlation of morphometric information obtained through an original digital colposcopy system in cervical intraepithelial neoplasia (CIN) and to establish its possible clinical applications

Methods

The size of the transformation zone and of colposcopic lesions was measured in 101 patients with evaluable colposcopy. In the 62 patients who underwent loop excision of the lesion these data were correlated with histologic lesion size

Results

The size of colposcopic lesions significantly increased with histologic grade (CIN-I, CIN-II, CIN-III: 90mm2, 134mm2 and 265mm2, respectively) and their location in the cervix was more central. A good correlation, nearly 85%, was found with size measured by histologic morphometry

Conclusions

The size of colposcopic CIN lesions is a good indicator of true lesion size. These results provide a new perspective on the management of low-grade lesions by offering an objective and reliable method for controlling their evolution

keywords:

Colposcopy

Image processing

Cervical intraepithelial neoplasia

Morphometry

Natural history

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