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Vol. 46. Issue 4.
Pages 177-180 (January 2003)
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Vol. 46. Issue 4.
Pages 177-180 (January 2003)
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Síndrome paraneoplásico cerebeloso asociado con carcinoma de ovario
Paraneoplastic syndrome with cerebellar degeneration associated with ovarian carcinoma
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M.C. Romero Fernándeza,*, M. Hensb, J.M. Moreno Montesinosa, M. Sánchez Hurtadoa, J. Gómez Ariasa, I. Ruizc, M.D. Rivera Acostaa, E. García Rea, A. Gilaberta
a Servicio de Obstetricia y Ginecología. Hospital General Universitario Ciudad de Jaén. Jaén
b Servicio de Neurología. Hospital General Universitario Ciudad de Jaén. Jaén
c Servicio de Anatomía Patológica. Hospital General Universitario Ciudad de Jaén. Jaén. España
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Resumen

Presentamos el caso de una paciente afectada de un síndrome paraneoplásico con degeneración cerebelosa, como primera manifestación de un tumor ovárico en la que todos los estudios resultaron normales, a excepción de la presencia de un autoanticuerpo anti-Yo, que reconoce antígenos citoplasmáticos de las células de Purkinje del cerebelo. La sospecha de un tumor ovárico fue confirmada microscópicamente tras la extirpación de los dos anejos

Summary

We describe a patient who presented paraneoplastic syndrome with cerebellar degeneration as the first manifestation of an ovarian tumour. The results of initial investigations were normal except for the presence of anti-Yo autoantibodies that recognized Purkinje cell cytoplasmic antigens of the cerebellum. Ovarian tumour was confirmed microscopically after extirpation of both ovaries

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Copyright © 2003. Sociedad Española de Ginecología y Obstetricia
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