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      "titulo" => "Carpogenic germination of <span class="elsevierStyleItalic">Sclerotinia sclerotiorum</span> sclerotia in Brassica oleracea var gemmifera &#40;VN&#58; Brussels sprouts&#41; in North Patagonia&#44; Argentina"
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            "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Brussels sprouts field affected by <span class="elsevierStyleItalic">S&#46; sclerotiorum</span> &#40;a&#41;&#46; Plants showing aerial-apical &#40;a&#41; and basal stem &#40;b&#41; infections&#46; Sclerotia on the ground &#40;c&#41;&#46; Sclerotia germinated in apothecia in soil &#40;d&#41;&#46; Asci with eight ascospores and paraphyses formed in the apothecium &#40;e&#41;&#46; Sclerotia development on PDA in a Petri plate after 7-d incubation &#40;f&#41;&#46;</p>"
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      "titulo" => "Genomic characterization of <span class="elsevierStyleItalic">Moraxella bovis</span> and <span class="elsevierStyleItalic">Moraxella bovoculi</span> Uruguayan strains isolated from calves with infectious bovine keratoconjunctivitis"
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            "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Benchmarking universal single-copy orthologs of assembled <span class="elsevierStyleItalic">M&#46; bovis</span> and <span class="elsevierStyleItalic">M&#46; bovoculi</span> genomes and their reference for Gamma-proteobacteria class&#46; Results of BUSCO run for <span class="elsevierStyleItalic">M&#46; bovis</span> and <span class="elsevierStyleItalic">M&#46; bovoculi</span> annotated genomes compared to their reference&#46; Top&#58; summary of BUSCO groups found for <span class="elsevierStyleItalic">M&#46; bovis&#46;</span> Bottom&#58; Venn diagram showing the complete and single-copy BUSCOs shared by <span class="elsevierStyleItalic">M&#46; bovis</span> and its reference genome &#40;A&#41;&#46; The same interpretation applies for <span class="elsevierStyleItalic">M&#46; bovoculi</span> &#40;B&#41;&#46;</p>"
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          "en" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Functional gene categorization &#40;&#37;&#41;&#46; &#40;1&#41; Cell cycle and DNA processing &#40;CCDP&#41;&#59; &#40;2&#41; cell fate &#40;CF&#41;&#59; &#40;3&#41; cell rescue&#44; defense and virulence &#40;CRDV&#41;&#59; &#40;4&#41; detoxification involving CYP450 &#40;DIC&#41;&#59; &#40;5&#41; energy &#40;EN&#41;&#59; &#40;6&#41; interaction of nutrients and nutritional adaptation &#40;INNA&#41;&#59; &#40;7&#41; metabolism &#40;ME&#41;&#59; &#40;8&#41; protein with binding function or cofactor requirement &#40;PBF&#41;&#59; &#40;9&#41; stress&#44; cell differentiation and biogenesis of cellular components &#40;SDBCC&#41;&#59; &#40;10&#41; transport and cellular communication &#40;TCC&#41;&#59; &#40;11&#41; transcription &#40;TPF&#41;&#59; &#40;12&#41; unclassified &#40;UNCL&#41; proteins and &#40;13&#41; implicated in several metabolic pathways &#40;SW&#41;&#46;</p>"
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    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Introduction</span><p id="par0020" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleItalic">Thecaphora frezii</span> &#40;<span class="elsevierStyleItalic">T&#46; frezii</span>&#41; is a fungus that infects peanut plants &#40;<span class="elsevierStyleItalic">Arachis hypogaea</span> L&#46;&#41;<a class="elsevierStyleCrossRef" href="#bib0200"><span class="elsevierStyleSup">4</span></a> which generates brown carbonaceous masses in fruits and leads to significant economic losses in these plantations&#46; These teliospores are resting structures that enable the fungus to overwinter and survive in the soil for years<a class="elsevierStyleCrossRef" href="#bib0355"><span class="elsevierStyleSup">35</span></a>&#46; When peanut pegs penetrate the soil&#44; their exudates disrupt teliospore dormancy&#44; promoting spore germination and&#44; thus&#44; local infections<a class="elsevierStyleCrossRef" href="#bib0255"><span class="elsevierStyleSup">15</span></a>&#46; This infection develops during peanut pegging&#46; The germination of teliospores comprises the development of a probasidium&#44; which leads to basidiospores <span class="elsevierStyleItalic">via</span> meiosis&#46; Once basidiospores germinate&#44; compatible haploid germ tubes fuse to form a mycelium&#44; responsible for the infection&#46; When peanut gynophores dig into the ground&#44; dikaryotic hyphae can pass through them&#44; colonize tissues&#44; and substitute cells with reddish-brown teliospores&#46; During shelling&#44; teliospores are released and remain on the soil&#44; where they can survive in a metabolically dormant state&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">Several pathogenic fungi for plants develop this transition from spores to hyphae to exert their lifecycle&#44; such as <span class="elsevierStyleItalic">Ustilago maydis</span> &#40;<span class="elsevierStyleItalic">U&#46; maydis</span>&#41;<a class="elsevierStyleCrossRef" href="#bib0320"><span class="elsevierStyleSup">28</span></a>&#44; <span class="elsevierStyleItalic">Microbotryum violaceum</span><a class="elsevierStyleCrossRef" href="#bib0320"><span class="elsevierStyleSup">28</span></a>&#44; <span class="elsevierStyleItalic">Ophiostoma ulmi</span><a class="elsevierStyleCrossRef" href="#bib0215"><span class="elsevierStyleSup">7</span></a>&#44; <span class="elsevierStyleItalic">Taphrina deformans</span><a class="elsevierStyleCrossRef" href="#bib0215"><span class="elsevierStyleSup">7</span></a> and <span class="elsevierStyleItalic">Holleya sinecauda</span><a class="elsevierStyleCrossRef" href="#bib0215"><span class="elsevierStyleSup">7</span></a>&#46; Note that <span class="elsevierStyleItalic">T&#46; frezii</span> belongs to the same smut class as <span class="elsevierStyleItalic">U&#46; maydis</span>&#44; and recent research on this fungus shows differential gene expression during teliospore germination<a class="elsevierStyleCrossRef" href="#bib0345"><span class="elsevierStyleSup">33</span></a> and increased protein level after 6<span class="elsevierStyleHsp" style=""></span>h from teliospore germination&#44; also along with an increase in RNA synthesis&#46; This morphological shift&#44; typically triggered by multiple environmental signals&#44; is tightly controlled by complex genetic pathways to ensure successful pathogenic development&#46; Mutation or drug inhibition of this passage has been shown to block the process of pathogenicity&#44; and it is a clear example of the biological event of cell differentiation&#44; representing a basic model for the study of this important phenomenon<a class="elsevierStyleCrossRef" href="#bib0310"><span class="elsevierStyleSup">26</span></a>&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">In this study&#44; we aim to identify some genes that are differentially expressed during the transition from teliospore to hyphal stage in the fungus <span class="elsevierStyleItalic">T&#46; frezii</span> according to specific <span class="elsevierStyleItalic">in vitro</span> culture conditions&#46; The findings obtained in this work will possibly contribute to understanding some of the biological mechanisms underlying <span class="elsevierStyleItalic">T&#46; frezii</span> development&#44; especially in this essential shift point&#44; which gives rise to the formation of basidiospores and later hyphae&#44; just before infective structures are formed&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Materials and methods</span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Collection&#44; isolation and cultivation of <span class="elsevierStyleItalic">Thecaphora frezii</span></span><p id="par0035" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleItalic">T&#46; frezii</span> teliospores were found in hypertrophic peanut pods&#44; indicating the presence of the disease&#46; Pods from plants grown in General Cabrera&#44; C&#243;rdoba&#44; Argentina&#44; were superficially disinfected with 0&#46;5&#37; NaOCl &#40;v&#47;v&#41;&#59; after that&#44; teliospores were obtained and disinfected with 5&#37; NaClO &#40;v&#47;v&#41;&#44; washed twice with sterile distilled water&#44; plated on potato-dextrose agar &#40;Britannia PDA&#41; and incubated at 26<span class="elsevierStyleHsp" style=""></span>&#176;C in the dark until germination<a class="elsevierStyleCrossRef" href="#bib0335"><span class="elsevierStyleSup">31</span></a>&#46; Daily observation and a count of colonies in PDA plates was made over 15 days&#44; to calculate the germination rate&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Nuclear staining of <span class="elsevierStyleItalic">Thecaphora frezii</span> hyphae</span><p id="par0040" class="elsevierStylePara elsevierViewall">Hyphae were stained according to Arias et al&#46;<a class="elsevierStyleCrossRef" href="#bib0190"><span class="elsevierStyleSup">2</span></a> Briefly&#44; they were incubated for 24<span class="elsevierStyleHsp" style=""></span>h in 70&#37; &#40;v&#47;v&#41; ethanol&#44; then washed with sterile distilled water and then treated with RNase A &#40;65<span class="elsevierStyleHsp" style=""></span>&#176;C&#44; 10<span class="elsevierStyleHsp" style=""></span>min&#41;&#46; Propidium iodide &#40;1&#37; v&#47;v&#41; was added for 10<span class="elsevierStyleHsp" style=""></span>min followed by two rinses with sterile distilled water&#46; Cell nuclei were visualized under a fluorescence microscopy Zeiss &#8211; Axio observer D1 &#40;Zeiss&#44; Germany&#41;&#46; The microscope was fitted with a Mono-camera AxioCam 506&#44; and images were processed using the Imaging Software ZEN 2 Core&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">RNA extraction</span><p id="par0045" class="elsevierStylePara elsevierViewall">Total RNA was extracted from both teliospores and hyphae of <span class="elsevierStyleItalic">T&#46; frezii</span> using the TRIzol reagent &#40;Invitrogen&#44; California&#44; USA&#41;&#44; following the manufacturer&#39;s instructions<a class="elsevierStyleCrossRef" href="#bib0330"><span class="elsevierStyleSup">30</span></a> &#40;Invitrogen&#44; California&#44; USA&#41;&#46; To initiate this process&#44; a pool of teliospores was created&#44; harvested from carbonaceous peanut pods from 20 distinct plants&#46; This sample was subsequently divided into two subsets&#46; One subset was designated for RNA extraction and subsequent RNAseq analysis and the second subset was employed to cultivate mycelia on PDA plates&#44; and RNA was later extracted from three separate plates&#46; To ensure the purity of the RNA samples&#44; genomic DNA was effectively eliminated through on-column digestion using DNase &#40;Qiagen&#44; Germany&#41; at the recommended concentration by the manufacturer&#46; The success of the RNA extraction process was evaluated in terms of both quality and quantity&#46; Potential RNA degradation and impurities were assessed using a 1&#46;5&#37; &#40;w&#47;v&#41; agarose gel&#44; while RNA purity was confirmed using a NanoPhotometer spectrophotometer &#40;Implen&#44; California&#44; USA&#41;&#46; RNA concentration was calculated using the Qubit RNA assay kit and Qubit Fluorometer 2&#46;0 &#40;Life Technologies&#44; California&#44; USA&#41;&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0055">Library preparation and RNA-Seq</span><p id="par0050" class="elsevierStylePara elsevierViewall">The cDNA library was prepared using the RNA of <span class="elsevierStyleItalic">T&#46; frezii</span>&#39;s teliospores and hyphae&#46; They were performed using the NEB Next Ultra RNA kit for Illumina &#40;Nebraska&#44; USA&#41; according to the manufacturer&#39;s instructions&#46; Briefly&#44; mRNA was purified from total RNA using poly-T oligo-attached magnetic beads&#46; Fragmentation was carried out with divalent cations under elevated temperature in NEB Next First Strand Synthesis Reaction Buffer &#40;5&#215;&#41;&#46; The first strand cDNA was synthesized using random hexamer primers and M-MuLV reverse transcriptase&#46; The second strand cDNA synthesis was subsequently performed using DNA polymerase I and RNase H&#46; cDNA was then size-selected and adaptor-ligated&#44; and the products were selectively enriched&#46; The clustering of the index-coded samples was performed on a cBot Cluster Generation System using TruSeq PE Cluster Kit v3-cBot-HS &#40;Illumina&#44; NEB&#44; USA&#41;&#44; following the manufacturer&#39;s instructions&#46;</p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0060">RNA-Seq data analysis</span><p id="par0055" class="elsevierStylePara elsevierViewall">The cDNA libraries were sequenced on Illumina HiSeq 1500 to generate 2&#215; 150<span class="elsevierStyleHsp" style=""></span>bp pair-end reads at the INDEAR service facilities &#40;Rosario&#44; Argentina&#41;&#46; Briefly&#44; a <span class="elsevierStyleItalic">de novo</span> transcriptome was assembled with all reads&#44; then the gene expression in each condition was measured with the counts per million &#40;CPM&#41; of reads&#46; RNA-Seq read quality was confirmed by FastQC software &#40;<a href="http://www.bioinformatics.babraham.ac.uk/projects/fastqc/">http&#58;&#47;&#47;www&#46;bioinformatics&#46;babraham&#46;ac&#46;uk&#47;projects&#47;fastqc&#47;</a>&#41; and compared &#40;teliospores and hyphae&#41;&#46; Fold change &#40;FC&#41; and statistical significance for all comparisons were determined <span class="elsevierStyleItalic">via</span> General Linear Model statistics using the EdgeR package version 3&#46;4&#46;2 of Bioconductor<a class="elsevierStyleCrossRef" href="#bib0305"><span class="elsevierStyleSup">25</span></a> in the R environment &#40;version 3&#46;0&#46;2&#44; R Core Team&#44; 2018&#41;<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">23</span></a>&#46;</p></span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065"><span class="elsevierStyleItalic">T&#46; frezii</span> differentially expressed genes from teliospore to hyphal stage</span><p id="par0060" class="elsevierStylePara elsevierViewall">Data obtained from RNA-Seq were used to identify differentially expressed genes&#44; involved in the <span class="elsevierStyleItalic">T&#46; frezii</span> life cycle&#44; during the transition from teliospore to hyphae&#46; A minimum 2-fold change up or down was the cut-off to consider whether a gene was positively or negatively differentially expressed&#46; However&#44; in specific cases&#44; less than 2-fold differences were considered&#44; particularly focusing on the different expression of certain genes that have been previously observed in other fungi&#46;</p><p id="par0065" class="elsevierStylePara elsevierViewall">FungiFun2<a class="elsevierStyleCrossRef" href="#bib0290"><span class="elsevierStyleSup">22</span></a>&#44; a tool for performing functional enrichment analysis of fungal genes&#44; was used to obtain functional annotation of the differentially expressed genes of <span class="elsevierStyleItalic">T&#46; frezii</span> teliospores and hyphae&#46; As <span class="elsevierStyleItalic">T&#46; frezii</span> is not present in the FungiFun2 database&#44; we used orthologous gene sequences from <span class="elsevierStyleItalic">U&#46; maydis</span> to assign functions to <span class="elsevierStyleItalic">T&#46; frezii</span> genes&#46;</p></span><span id="sec0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">qPCR analysis of selected genes</span><p id="par0070" class="elsevierStylePara elsevierViewall">For the study of quantitative expression by real-time PCR&#44; some of the differentially expressed genes in the transition from teliospores to hyphae were selected&#46; The oligonucleotide list for the genes &#40;some genes differentially expressed in other fungal species were selected&#41; were designed using the Primer-Blast program &#40;NCBI&#44; NIH&#41; &#40;<a class="elsevierStyleCrossRef" href="#sec0110">Table S1</a>&#41;&#46; Quantification of gene expression was performed through the real-time PCR detection system StepOne Plus Real-Time PCR system&#174; &#40;ThermoFisher&#44; Massachusetts&#44; USA&#41;&#46;</p><p id="par0075" class="elsevierStylePara elsevierViewall">cDNA was prepared from the same RNA samples as those used for RNA-Seq analysis&#44; using the enzyme SuperScript&#174; III Reverse Transcriptase &#40;Invitrogen&#59; Thermo Fisher Scientific&#8482;&#44; USA&#41; and following the manufacturer&#39;s recommendations&#46; The qPCR was performed with three biological replicates using the Sybr&#174; Green Master Mix kit &#40;Applied Biosystems&#59; Thermo Fisher Scientific&#44; California&#44; USA&#41;&#44; following the manufacturer&#39;s recommendations&#46;</p><p id="par0080" class="elsevierStylePara elsevierViewall">Relative gene expression was performed using the actin transcript as a reference gene for expression normalization &#40;this gene is highly used for fungal gene expression normalization<a class="elsevierStyleCrossRefs" href="#bib0280"><span class="elsevierStyleSup">20&#44;29</span></a>&#41;&#46; The program used for all the targets was&#58; 95<span class="elsevierStyleHsp" style=""></span>&#176;C for 3<span class="elsevierStyleHsp" style=""></span>min&#44; 40 cycles of 95<span class="elsevierStyleHsp" style=""></span>&#176;C for 10<span class="elsevierStyleHsp" style=""></span>s and 60<span class="elsevierStyleHsp" style=""></span>&#176;C for 30<span class="elsevierStyleHsp" style=""></span>s&#46; Fluorescence was read after this step&#46; At the end of the program&#44; temperature was reduced from 95<span class="elsevierStyleHsp" style=""></span>&#176;C to 65<span class="elsevierStyleHsp" style=""></span>&#176;C at a rate ramp of 0&#46;1<span class="elsevierStyleHsp" style=""></span>&#176;C&#47;s&#44; which allowed evaluation of the melting curves for each reaction&#46; The specificity of the amplicons was verified by analyzing the melting curves and by sequencing the fragments obtained&#46; The expression change in the target gene&#44; relative to actin expression&#44; was calculated using the 2<span class="elsevierStyleSup">&#8722;&#916;&#916;CT</span> method<a class="elsevierStyleCrossRef" href="#bib0245"><span class="elsevierStyleSup">13</span></a>&#46; The mean and SE &#40;&#177;&#41; were then determined for each of the different samples&#46;</p></span><span id="sec0050" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Statistical analysis</span><p id="par0085" class="elsevierStylePara elsevierViewall">Statistical analysis was conducted using the InfoStat Software<a class="elsevierStyleCrossRef" href="#bib0300"><span class="elsevierStyleSup">24</span></a>&#46; All data were calculated as the mean<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>standard deviation&#46; Heat map graphical representation was performed using Pheatmap package version 1&#46;0&#46;12 in RStudio &#40;2022&#46;07&#46;1 Build 554&#44; R environment version 4&#46;2&#46;1&#41;&#46; Genes were grouped based on gene expression levels in a hierarchical clustering process&#46;</p></span><span id="sec0055" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Gene accession numbers</span><p id="par0090" class="elsevierStylePara elsevierViewall">Accession numbers of all genes &#40;mRNA&#41; used in this study are listed in <a class="elsevierStyleCrossRefs" href="#tbl0005">Tables 1&#8211;3</a> and <a class="elsevierStyleCrossRef" href="#sec0110">S1&#8211;S3</a>&#46;</p></span></span><span id="sec0060" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Results</span><p id="par0095" class="elsevierStylePara elsevierViewall">In this manuscript&#44; a transcriptomic analysis was performed focusing on the transition from teliospores to hyphae&#46; Total RNA from both structures of <span class="elsevierStyleItalic">T&#46; frezii</span> was successfully extracted using the TRIzol protocol providing an acceptable RNA recovery yield and quality and was used to prepare the cDNA library for a comparative analysis of expression between both stages&#46;</p><span id="sec0065" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">Identification of <span class="elsevierStyleItalic">T&#46; frezii</span> genes involved in the transition from teliospore to hyphae</span><p id="par0100" class="elsevierStylePara elsevierViewall">Transcription levels were compared between two <span class="elsevierStyleItalic">T&#46; frezii</span> stages &#40;teliospores and hyphae&#41;&#46; RNA was obtained from teliospores from peanut pods with disease symptoms&#44; and hyphae were obtained from the germination of these disinfected spores in PDA&#46; Daily observation of the plates showed different structures of the fungal life cycle&#44; as observed in <a class="elsevierStyleCrossRef" href="#fig0005">Figures 1A and B</a> where we show the formation of probasidia and basidiospores&#46; After 10 days&#44; 0&#46;72<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>0&#46;01&#37; teliospores germinated&#44; leading to the development of typical <span class="elsevierStyleItalic">T&#46; frezii</span> mycelium&#46; Nuclei stained with propidium iodide and observed in fluorescence microscopy revealed that 100&#37; of the stained hyphae were monokaryotic &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>C&#41;&#46; Under these conditions&#44; 200 genes were differentially expressed&#58; 134 were up-regulated&#44; and 66 were down-regulated in the hyphal stage&#46; Based on the RNA sequences obtained&#44; protein sequences were deduced and analyzed by BLASTp of non-redundant protein sequences in the National Center for Biotechnology Information &#40;NCBI&#41;<a class="elsevierStyleCrossRef" href="#bib0360"><span class="elsevierStyleSup">36</span></a>&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia></span><span id="sec0070" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0095">Functional grouping of differentially expressed genes</span><p id="par0105" class="elsevierStylePara elsevierViewall"><a class="elsevierStyleCrossRef" href="#fig0010">Figure 2</a> displays the functional grouping of all the genes that exhibited differential expression in response to the germination of teliospores into hyphae&#46; We classified those genes into&#58; &#40;1&#41; cell cycle and DNA processing &#40;CCDP&#41;&#59; &#40;2&#41; cell fate &#40;CF&#41;&#59; &#40;3&#41; cell rescue&#44; defense and virulence &#40;CRDV&#41;&#59; &#40;4&#41; detoxification involving CYP450 &#40;DIC&#41;&#59; &#40;5&#41; energy &#40;EN&#41;&#59; &#40;6&#41; interaction of nutrients and nutritional adaptation &#40;INNA&#41;&#59; &#40;7&#41; metabolism &#40;ME&#41;&#59; &#40;8&#41; protein with binding function or cofactor requirement &#40;PBF&#41;&#59; &#40;9&#41; stress&#44; cell differentiation and biogenesis of cellular components &#40;SDBCC&#41;&#59; &#40;10&#41; transport and cellular communication &#40;TCC&#41;&#59; &#40;11&#41; transcription &#40;TPF&#41;&#59; &#40;12&#41; unclassified &#40;UNCL&#41; proteins and &#40;13&#41; involved in several metabolic pathways &#40;SW&#41;&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0110" class="elsevierStylePara elsevierViewall">From the total number of differentially expressed genes&#44; three categories showed the greatest contribution&#58; those involved in metabolism &#40;<a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>&#59; 66 genes&#41;&#59; in transport and cellular communication &#40;<a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a>&#59; 41 genes&#41; and those encoding unclassified proteins &#40;<a class="elsevierStyleCrossRef" href="#sec0110">Table S2</a>&#59; 23 genes&#41;&#44; with a contribution of 33&#37;&#44; 20&#46;5&#37; and 11&#46;5&#37; respectively&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><p id="par0115" class="elsevierStylePara elsevierViewall">When we analyzed genes expressed and involved in the metabolism category &#40;<a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>&#41;&#44; 52 up-regulated and 14 down-regulated genes were found in <span class="elsevierStyleItalic">T&#46; frezii</span> growth from teliospores to hyphae&#46; Among up-regulated genes in teliospores&#44; we found the cytochrome-C peroxidase gene &#40;MW691239&#41; transcript increased 14&#46;08 times in teliospores&#44; and GAPDH transcript &#40;MW691253&#41;&#44; its level is 8&#46;40-fold higher in the teliospore stage&#44; compared to the hyphal stage&#46; In the same group&#44; we observed an 85&#46;75-fold increase in haloacid dehalogenase-like hydrolase &#40;MW691229&#41; in <span class="elsevierStyleItalic">T&#46; frezii</span> teliospores&#44; and a 19&#46;74-fold increase was measured in this stage for glutaminase A enzyme &#40;MW691236&#41;&#46; The enzyme 2-methylcitrate dehydratase &#40;MW691261&#41; was observed in <span class="elsevierStyleItalic">T&#46; frezii</span> teliospores&#44; the transcription level experienced a 7&#46;12-fold increase&#44; compared to hyphae&#46; The gene glycerol 2-dehydrogenase &#40;NADP&#40;&#43;&#41;&#41; &#40;MW691268&#41;&#44; which plays a role in glycerol catabolism&#44; exhibited a substantial 4&#46;87-fold increase in expression levels within <span class="elsevierStyleItalic">T&#46; frezii</span> teliospores compared to hyphae&#46; Similarly&#44; the RNA expression of UTP-glucose-1-phosphate uridyltransferase &#40;MW691270&#41; was enhanced by 4&#46;72-fold in teliospores of <span class="elsevierStyleItalic">T&#46; frezii&#46;</span></p><p id="par0120" class="elsevierStylePara elsevierViewall">Within genes down-regulated in teliospores&#44; we found that the aldo-keto reductase yakc &#91;NADP&#43;&#93; &#40;MW691282&#41;&#44; an enzyme from the reductase superfamily&#44; exhibited a 1&#46;63-fold decrease in <span class="elsevierStyleItalic">T&#46; frezii</span> teliospores in relation to hyphae&#46; Additionally&#44; we observed down-regulation in two other gene expressions&#58; Fer6&#44; associated with ATP-binding cassette transporter protein &#40;MW691283&#41;&#44; showed a 1&#46;91-fold decrease&#44; while Fer5&#44; linked to N6-hydroxylysine acetyl transferase &#40;MW691284&#41;&#44; exhibited a 2&#46;74-fold decrease&#46; A decrease in the expression of two additional genes was observed in teliospores of <span class="elsevierStyleItalic">T&#46; frezii</span>&#46; The gene related to 7 alpha-cephem-methoxylase P8 chain &#40;MW691288&#41; showed a significant 8&#46;33-fold decrease&#44; while the expression of the gene related to peroxisomal amine oxidase &#40;copper-containing&#41; &#40;MW691292&#41; was down-regulated by a substantial 18&#46;86-fold&#46;</p><p id="par0125" class="elsevierStylePara elsevierViewall">In the TCC category &#40;<a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a>&#41;&#44; we observed a total of 21 up-regulated genes and 20 down-regulated genes in <span class="elsevierStyleItalic">T&#46; frezii</span> during the transition from teliospores to hyphae&#46; Among the up-regulated genes&#44; we identified the aspartic protease &#40;MW691301&#41; gene&#44; which exhibited a substantial 9&#46;34-fold increase in teliospore expression&#46; Additionally&#44; the genes probable MET22 &#8211; protein ser&#47;thr phosphatase &#40;MW691299&#41; and related to putative monooxygenase &#40;MW691314&#41; were also found to be up-regulated in <span class="elsevierStyleItalic">T&#46; frezii</span> teliospores&#44; with fold increases of 13&#46;65 and 1&#46;13&#44; respectively&#46;</p><p id="par0130" class="elsevierStylePara elsevierViewall">One of the most prominently down-regulated genes was the amino acid permease &#40;MW691333&#41;&#44; which exhibited a substantial 35&#46;90-fold decrease in expression in <span class="elsevierStyleItalic">T&#46; frezii</span> teliospores&#46; Additionally&#44; among the other down-regulated genes&#44; we observed a decrease in expression for those related to acetate kinase &#40;MW691315&#41;&#44; to opsin-1 &#40;MW691321&#41;&#44; and an uncharacterized protein &#40;um02763&#41; &#40;MW691322&#41; with fold decreases of 1&#46;59&#44; 4&#46;96&#44; and 5&#46;39&#44; respectively&#46; Furthermore&#44; in relation to the autophagy-related protein &#40;MoAtg14&#41; &#40;MW691320&#41;&#44; <span class="elsevierStyleItalic">T&#46; frezii</span> showed a significant 4&#46;37-fold decrease in expression levels when comparing teliospores to hyphae&#46;</p><p id="par0135" class="elsevierStylePara elsevierViewall">In the categories of CCDP&#44; CF&#44; CRDV&#44; DIC&#44; EN&#44; INNA&#44; PBF&#44; SDBCC and TPF &#40;<a class="elsevierStyleCrossRef" href="#tbl0015">Table 3</a>&#41;&#44; 22 up-regulated genes were found &#40;2&#44; 0&#44; 5&#44; 1&#44; 6&#44; 1&#44; 1&#44; 4 and 2 respectively&#41; and 13 down-regulated genes &#40;4&#44; 2&#44; 1&#44; 1&#44; 0&#44; 0&#44; 0&#44; 1 and 4 respectively&#41; in <span class="elsevierStyleItalic">T&#46; frezii</span> transition from teliospores to hyphae&#46;</p><elsevierMultimedia ident="tbl0015"></elsevierMultimedia><p id="par0140" class="elsevierStylePara elsevierViewall">In the cell cycle and DNA processing category&#44; two genes were shown to be up-regulated in <span class="elsevierStyleItalic">T&#46; frezii</span> teliospores&#44; Clb2 &#40;b-type cyclin 2&#41; &#40;MW691335&#41; and the gene related to G1&#47;S-specific cyclin &#40;MW691336&#41; &#40;fold increases of 2&#46;2 and 1&#46;73&#44; respectively&#41;&#46; In the cell rescue&#44; defense and virulence category&#44; the peroxisomal membrane protein &#40;MW691347&#41; was 7&#46;36-fold up-regulated at RNA level in <span class="elsevierStyleItalic">T&#46; frezii</span> teliospores&#46; We also found a 14&#46;27-fold increase in the Hsp70 protein &#40;MW691345&#41; in teliospores&#46; With regard to the synthesis of chitin&#44; one of the most important components of the fungal cell wall&#44; we found that one of the genes that codes for chitin synthase &#40;MW691346&#41; increased 13&#46;01-fold in teliospores&#44; compared to the hyphal stage in <span class="elsevierStyleItalic">T&#46; frezii</span>&#46; In DIC category&#44; we found just one up-regulated gene&#44; the sterol 14 alpha-demethylase &#40;MW691349&#41;&#44; an essential enzyme in sterol biosynthesis&#44; which was 5&#46;53-fold up-regulated in <span class="elsevierStyleItalic">T&#46; frezii</span> teliospores&#46; In SDBCC category&#44; some of the up-regulated genes in <span class="elsevierStyleItalic">T&#46; frezii</span> teliospores were those related to CDC20 &#8211; cell division control protein &#40;MW691359&#41;&#44; to YSC84 &#8211; a protein involved in the organization of actin cytoskeleton &#40;MW691361&#41; and to chitinase A precursor &#40;MW691362&#41; &#40;25&#46;06&#44; 4&#46;99&#44; 2&#46;36 respectively&#41;&#46; One of the proteins related to nutritional adaptation function&#44; the putative neutral amino acid permease &#40;MW691357&#41;&#44; was found to be 9&#46;71-fold up-regulated in <span class="elsevierStyleItalic">T&#46; frezii</span> teliospores&#46; In the energy category&#44; we found the enoyl-&#40;acyl carrier protein&#41; reductase &#40;MW691352&#41;&#44; which is the last enzyme in the fatty acid elongation cycle<a class="elsevierStyleCrossRef" href="#bib0275"><span class="elsevierStyleSup">19</span></a>&#44; its expression exhibited a 27&#46;10-fold increase in <span class="elsevierStyleItalic">T&#46; frezii</span> teliospores&#46;</p><p id="par0145" class="elsevierStylePara elsevierViewall">In our analysis of down-regulated genes in teliospores&#44; we observed significant decreases in the expression of two genes belonging to the cell fate category&#58; Ssp1 protein kinase &#40;MW691342&#41; and the inhibitor of apoptosis-promoting Bax1 &#40;MW691341&#41;<a class="elsevierStyleCrossRef" href="#bib0225"><span class="elsevierStyleSup">9</span></a>&#46; These genes exhibited a remarkable 18&#46;32 and 17&#46;37-fold reduction&#44; respectively&#46; The gene that encodes for putative Rer1 family protein &#40;MW691367&#41; was also down-regulated in teliospores&#46;</p><p id="par0150" class="elsevierStylePara elsevierViewall">Regarding the genes that participate in multiple pathways &#40;<a class="elsevierStyleCrossRef" href="#sec0110">Table S3</a>&#41;&#44; a total of 26 up-regulated genes and 9 down-regulated genes were identified&#46; Notably&#44; probable adenosylhomocysteinase &#40;MW691399&#41; exhibited a substantial 6&#46;93-fold increase&#44; while probable SMC2 &#8211; a chromosome segregation protein &#40;MW691373&#41; showed a modest 1&#46;09-fold up-regulation&#46; In contrast&#44; PacC &#8211; a transcription factor &#40;MW691404&#41;&#44; experienced a remarkable 2&#46;48-fold down-regulation&#46; We also found three other up-regulated genes&#44; TPM2 &#8211; tropomyosin isoform 2 &#40;MW691380&#41;&#44; mitochondrial porin &#40;MW691376&#41;&#44; and CipC homolog &#40;MW691370&#41;&#44; which were 7&#46;40&#44; 5&#46;00&#44; and 8&#46;44-fold increased&#44; respectively&#46;</p><p id="par0155" class="elsevierStylePara elsevierViewall">In the unclassified genes category &#40;<a class="elsevierStyleCrossRef" href="#sec0110">Table S2</a>&#41;&#44; during the transition from teliospores to the hyphal stage&#44; a total of 13 up-regulated genes and 10 down-regulated genes were observed&#46; Notably&#44; the um10414 protein &#40;MW691406&#41; exhibited a significant up-regulation&#44; with a remarkable 49&#46;29-fold increase in gene expression&#46; On the other hand&#44; the genes encoding for um05276 &#40;MW691418&#41;&#44; um10868 &#40;MW691421&#41;&#44; um04575 &#40;MW691424&#41;&#44; and um10208 &#40;MW691425&#41; showed down-regulation&#44; with their expression levels exhibiting 1&#46;45&#44; 1&#46;72&#44; 12&#46;50&#44; and 15&#46;74-fold decreases&#44; respectively&#46;</p></span><span id="sec0075" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0100">qPCR analysis of selected genes</span><p id="par0160" class="elsevierStylePara elsevierViewall">To validate the reliability of the transcriptome sequencing&#44; we selected 15 differentially expressed genes of the two <span class="elsevierStyleItalic">T&#46; frezii</span> stages &#40;teliospore and mycelium&#41; for RT-qPCR analysis&#46; The results showed that 7 of the 15 genes selected were up-regulated and 8 were down-regulated &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>&#41;&#46; Our results were consistent with the transcriptome data&#46; Differences were significant in all cases &#40;<span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#46;02&#41; except for those related to acetate kinase gene&#46;</p><elsevierMultimedia ident="fig0015"></elsevierMultimedia></span></span><span id="sec0080" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0105">Discussions</span><p id="par0165" class="elsevierStylePara elsevierViewall">To date&#44; no comprehensive investigation has been carried out to analyze the gene regulation occurring during the life cycle of <span class="elsevierStyleItalic">T&#46; frezii</span>&#46; Our work allowed to identify genes that are differentially expressed in two stages&#44; teliospore and hypha&#46; As described for other smut fungi&#44; after teliospore germination and meiosis&#44; haploid sporidia are formed and cell fusion of two haploid mating types leads to the development of infectious dikaryotic hyphae&#46; This process occurs on the host plant&#44; during the mating process between cells of opposite mating types<a class="elsevierStyleCrossRef" href="#bib0355"><span class="elsevierStyleSup">35</span></a>&#46; However&#44; as observed in <span class="elsevierStyleItalic">Cryptococcus neoformans</span><a class="elsevierStyleCrossRef" href="#bib0350"><span class="elsevierStyleSup">34</span></a>&#44; a shift from teliospores to monokaryotic hyphae was found in <span class="elsevierStyleItalic">in vitro</span><span class="elsevierStyleItalic">T&#46; frezii</span> cultures&#46;</p><span id="sec0085" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0110">Genes that code for proteins involved in metabolism</span><p id="par0170" class="elsevierStylePara elsevierViewall">By examining the expression patterns of specific genes&#44; we identified the cytochrome-C peroxidase gene &#40;MW691239&#41; where the transcript showed a remarkable 14-fold increase in teliospores&#46; It is noteworthy that in the fungus <span class="elsevierStyleItalic">Candida albicans</span>&#44; this protein has been targeted for antifungal treatment using quinonemethide<a class="elsevierStyleCrossRef" href="#bib0315"><span class="elsevierStyleSup">27</span></a>&#44; which effectively reduces its expression&#46; Hence&#44; considering this relationship&#44; it could be proposed as a potential alternative for controlling <span class="elsevierStyleItalic">T&#46; frezii</span>&#46; Furthermore&#44; our analysis of the expression levels of the GAPDH transcript &#40;MW691253&#41; revealed an 8-fold increase in the teliospore stage&#59; this finding aligns with observations made in <span class="elsevierStyleItalic">Penicillium marneffei</span><a class="elsevierStyleCrossRef" href="#bib0235"><span class="elsevierStyleSup">11</span></a> where there was an impressive 20-fold increase in the expression of this gene&#46; This gene is described to encode an enzyme that plays a crucial role in an adhesion factor for conidial attachment&#46; We also made a discovery regarding haloacid dehalogenase-like hydrolase &#40;MW691229&#41; which has been previously identified as an important virulence factor in <span class="elsevierStyleItalic">Pyrenophora teres f&#46; teres</span><a class="elsevierStyleCrossRef" href="#bib0230"><span class="elsevierStyleSup">10</span></a>&#46; Notably&#44; the expression of this gene is substantially elevated in <span class="elsevierStyleItalic">T&#46; frezii</span> teliospores&#46; In <span class="elsevierStyleItalic">U&#46; maydis</span>&#44; the transcriptomic analysis revealed a 3-fold increase&#44; while the protein analysis indicated a 2&#46;0&#8211;2&#46;2-fold induction<a class="elsevierStyleCrossRef" href="#bib0195"><span class="elsevierStyleSup">3</span></a>&#46; Conversely&#44; the glutaminase A enzyme &#40;MW691236&#41; exhibits a striking 85-fold increase in RNA levels in <span class="elsevierStyleItalic">U&#46; maydis</span>&#44; compared to a near 20-fold increase in <span class="elsevierStyleItalic">T&#46; frezii</span> teliospores<a class="elsevierStyleCrossRef" href="#bib0195"><span class="elsevierStyleSup">3</span></a>&#46; Furthermore&#44; the enzyme 2-methylcitrate dehydratase &#40;MW691261&#41; exhibited a 1&#46;81-fold increase at the protein level in <span class="elsevierStyleItalic">U&#46; maydis</span>&#44; coinciding with a nearly 7-fold increase in transcription levels in <span class="elsevierStyleItalic">T&#46; frezii</span> teliospores<a class="elsevierStyleCrossRef" href="#bib0265"><span class="elsevierStyleSup">17</span></a>&#46; Glycerol 2-dehydrogenase &#40;NADP&#40;&#43;&#41;&#41; &#40;MW691268&#41; has been identified as a key player in glycerol catabolism under microaerobic conditions in <span class="elsevierStyleItalic">U&#46; maydis</span>&#46; Interestingly&#44; in <span class="elsevierStyleItalic">T&#46; frezii</span> teliospores&#44; its expression level showed a significant nearly 5-fold increase compared to hyphae&#46; This notable increase in protein expression was also observed in <span class="elsevierStyleItalic">U&#46; maydis</span><a class="elsevierStyleCrossRef" href="#bib0195"><span class="elsevierStyleSup">3</span></a>&#46; Additionally&#44; in our study&#44; we found a consistent 5-fold increase in the expression of UTP-glucose-1-phosphate uridyltransferase &#40;MW691270&#41; at the protein level both in <span class="elsevierStyleItalic">U&#46; maydis</span><a class="elsevierStyleCrossRef" href="#bib0195"><span class="elsevierStyleSup">3</span></a> and <span class="elsevierStyleItalic">T&#46; frezii</span> teliospores&#46;</p><p id="par0175" class="elsevierStylePara elsevierViewall">Aldo-keto reductase yakc &#91;NADP&#43;&#93; &#40;MW691282&#41;&#44; nearly experienced a 2-fold decrease in <span class="elsevierStyleItalic">T&#46; frezii</span> teliospores in relation to hyphae&#46; This enzyme from the reductase superfamily&#44; also showed a 1&#46;97-fold decrease &#40;at protein level&#41; in <span class="elsevierStyleItalic">U&#46; maydis</span><a class="elsevierStyleCrossRef" href="#bib0265"><span class="elsevierStyleSup">17</span></a>&#46; Both Fer6&#44; which is associated with ATP-binding cassette transporter protein &#40;MW691283&#41;&#44; and Fer5&#44; linked to N6-hydroxylysine acetyl transferase &#40;MW691284&#41;&#44; exhibited approximately a 2-fold downregulation in <span class="elsevierStyleItalic">T&#46; frezii</span> teliospores compared to hyphae&#46; In contrast&#44; in <span class="elsevierStyleItalic">U&#46; maydis</span>&#44; the same genes demonstrated a much more pronounced down-regulation with 80&#46;5 and 165&#46;4-fold decrease &#40;RNA&#41; respectively&#46; A decrease in the expression of those related to 7 alpha-cephem-methoxylase P8 chain &#40;MW691288&#41; was observed both in teliospores of <span class="elsevierStyleItalic">T&#46; frezii</span> and of <span class="elsevierStyleItalic">U&#46; maydis</span> &#40;8 and 2 times&#44; respectively&#41;<a class="elsevierStyleCrossRef" href="#bib0270"><span class="elsevierStyleSup">18</span></a>&#46; In the same article&#44; the expression of those related to peroxisomal amine oxidase &#40;copper-containing&#41; &#40;MW691292&#41; was found to be down-regulated by 61-fold in <span class="elsevierStyleItalic">U&#46; maydis</span><a class="elsevierStyleCrossRef" href="#bib0270"><span class="elsevierStyleSup">18</span></a> and we found a nearly 19-fold decrease in teliospores of <span class="elsevierStyleItalic">T&#46; frezii</span>&#46;</p></span><span id="sec0090" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0115">Genes involved in transport and cellular communication</span><p id="par0180" class="elsevierStylePara elsevierViewall">During our gene expression analysis focused on proteins involved in transport and cell communication processes&#44; we made a remarkable observation regarding the expression of aspartic protease &#40;MW691301&#41;&#44; known as a protein expressed during the early stages of sunflower cotyledon infection by <span class="elsevierStyleItalic">Sclerotinia sclerotiorum</span><a class="elsevierStyleCrossRef" href="#bib0285"><span class="elsevierStyleSup">21</span></a>&#46; In <span class="elsevierStyleItalic">T&#46; frezii</span>&#44; in the teliospore stage&#44; the expression of this enzyme exhibited a significant 9&#46;34-fold increase&#46; Notably&#44; in <span class="elsevierStyleItalic">Paracoccidioides brasiliensis</span> fungi&#44; during the infection process&#44; this gene was up-regulated by 9&#46;5-fold<a class="elsevierStyleCrossRef" href="#bib0205"><span class="elsevierStyleSup">5</span></a>&#44; suggesting its potential importance in the infection process&#46; Comparisons in the expression levels of several genes with their orthologues of <span class="elsevierStyleItalic">U&#46; maydis</span> are compiled in the work of Ruiz-Herrera et al&#46;<a class="elsevierStyleCrossRef" href="#bib0270"><span class="elsevierStyleSup">18</span></a> Among these comparisons&#44; it was observed that the genes encoding for probable MET22 &#8211; protein ser&#47;thr phosphatase &#40;MW691299&#41; and related to putative monooxygenase &#40;MW691314&#41; were up-regulated in both <span class="elsevierStyleItalic">T&#46; frezii</span> and <span class="elsevierStyleItalic">U&#46; maydis</span>&#44; showing 13&#46;65 and 1&#46;13-fold changes in <span class="elsevierStyleItalic">T&#46; frezii</span>&#44; and 2&#46;3 and 2&#46;5 in <span class="elsevierStyleItalic">U&#46; maydis</span>&#44; respectively&#46;</p><p id="par0185" class="elsevierStylePara elsevierViewall">In terms of down-regulated genes&#44; the authors reported that the genes related to acetate kinase &#40;MW691315&#41;&#44; related to opsin-1 &#40;MW691321&#41;&#44; and uncharacterized protein &#40;um02763&#41; &#40;MW691322&#41; exhibited down-regulation in the same direction in <span class="elsevierStyleItalic">U&#46; maydis</span>&#46; The fold changes observed were 1&#46;59&#44; 4&#46;96&#44; and 5&#46;39 in <span class="elsevierStyleItalic">T&#46; frezii</span>&#44; and 10&#46;9&#44; 5&#44; and 114 in <span class="elsevierStyleItalic">U&#46; maydis</span>&#44; respectively&#46; One of the most significant down-regulated genes identified was the amino acid permease &#40;MW691333&#41;&#44; which plays a fundamental role in fluconazole resistance and is the target of plant secondary metabolites with antifungal properties&#46; In <span class="elsevierStyleItalic">U&#46; maydis</span>&#44; it exhibited specific expression during budding<a class="elsevierStyleCrossRef" href="#bib0210"><span class="elsevierStyleSup">6</span></a>&#44; while in <span class="elsevierStyleItalic">T&#46; frezii</span> hyphae&#44; its expression showed a 36-fold increase&#46; With regard to the autophagy-related protein &#40;MoAtg14&#41; &#40;MW691320&#41;&#44; a study conducted by Liu et al&#46;<a class="elsevierStyleCrossRef" href="#bib0240"><span class="elsevierStyleSup">12</span></a>&#44; demonstrated that the deletion of this protein in <span class="elsevierStyleItalic">Magnaporthe oryzae</span> resulted in a complete loss of virulence and conidiation problems&#46; However&#44; contrary to our expectations&#44; <span class="elsevierStyleItalic">T&#46; frezii</span>&#44; exhibited a decreased 4&#46;37-fold expression during the fungi transition&#46;</p></span><span id="sec0095" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0120">Genes that code for proteins involved in CCDP&#44; CF&#44; CRDV&#44; DIC&#44; EN&#44; INNA&#44; PBF&#44; SDBCC and TPF</span><p id="par0190" class="elsevierStylePara elsevierViewall">In the cell cycle and DNA processing category&#44; only two genes were shown to be up-regulated during the transition in both <span class="elsevierStyleItalic">T&#46; frezii</span> and <span class="elsevierStyleItalic">U&#46; maydis</span>&#44; Clb2 &#40;b-type cyclin 2&#41; &#40;MW691335&#41; and those related to G1&#47;S-specific cyclin &#40;MW691336&#41;<a class="elsevierStyleCrossRef" href="#bib0270"><span class="elsevierStyleSup">18</span></a>&#46;</p><p id="par0195" class="elsevierStylePara elsevierViewall">In the cell rescue&#44; defense&#44; and virulence category&#44; the peroxisomal membrane protein &#40;MW691347&#41; exhibited a significant up-regulation of nearly 7-fold in <span class="elsevierStyleItalic">T&#46; frezii</span>&#46; Similarly&#44; at the protein level&#44; it showed a 2&#46;31-fold up-regulation in <span class="elsevierStyleItalic">U&#46; maydis</span><a class="elsevierStyleCrossRef" href="#bib0265"><span class="elsevierStyleSup">17</span></a>&#46; Another up-regulated gene encoding for the Hsp70 protein &#40;MW691345&#41; is considered essential for many cellular processes and plays a major role in various stress conditions&#46; Its synthesis is induced by heat shock stress&#44; as observed in <span class="elsevierStyleItalic">U&#46; maydis</span> with a 5-fold increase in heating conditions<a class="elsevierStyleCrossRef" href="#bib0220"><span class="elsevierStyleSup">8</span></a>&#46; It has also been observed to be up-regulated during plant pathogenesis<a class="elsevierStyleCrossRef" href="#bib0340"><span class="elsevierStyleSup">32</span></a>&#46; Concerning the synthesis of chitin&#44; we found that one of the genes that codes for chitin synthase &#40;MW691346&#41;<a class="elsevierStyleCrossRef" href="#bib0330"><span class="elsevierStyleSup">30</span></a> is 13-fold up-regulated in teliospores of <span class="elsevierStyleItalic">T&#46; frezii</span>&#46; Interestingly&#44; this gene has been previously reported to be exclusive to the hyphae stage in the fungus <span class="elsevierStyleItalic">Mucor circinelloides</span><a class="elsevierStyleCrossRef" href="#bib0250"><span class="elsevierStyleSup">14</span></a>&#44; highlighting its differential expression during the transition process&#46; These findings support the existence of a multigene chitin synthase family&#44; where expression varies according to the fungal stage&#46; This suggests that different chitin synthase activities may play distinct roles in the dimorphic growth of <span class="elsevierStyleItalic">M&#46; circinelloides</span>&#46;</p><p id="par0200" class="elsevierStylePara elsevierViewall">Another up-regulated gene expressed in <span class="elsevierStyleItalic">T&#46; frezii</span> is sterol 14 alpha-demethylase &#40;MW691349&#41;&#44; which participates in sterol biosynthesis in eukaryotes and is a clinical target for antifungal azoles&#44; and was also up-regulated in <span class="elsevierStyleItalic">U&#46; maydis</span><a class="elsevierStyleCrossRef" href="#bib0270"><span class="elsevierStyleSup">18</span></a> &#40;2&#46;7 times&#41;&#46; The authors also reported up-regulation of genes related to CDC20 &#8211; cell division control protein &#40;MW691359&#41;&#44; YSC84 &#40;MW691361&#41; and chitinase A precursor &#40;MW691362&#41; in <span class="elsevierStyleItalic">U&#46; maydis</span><a class="elsevierStyleCrossRef" href="#bib0270"><span class="elsevierStyleSup">18</span></a> &#40;with 2&#46;5&#44; 2&#46;0&#44; 6&#46;7-fold increases&#44; respectively&#41;&#46; A notable virulence factor found in various fungi&#44; including <span class="elsevierStyleItalic">Saccharomyces cerevisiae</span> and <span class="elsevierStyleItalic">Candida albicans</span>&#44; is associated with a neutral amino acid permease &#40;MW691357&#41;<a class="elsevierStyleCrossRef" href="#bib0260"><span class="elsevierStyleSup">16</span></a>&#46; Research reveals that these fungi possess twenty-four and twenty-seven genes&#44; respectively&#44; that encode for this protein&#44; further contributing to their virulence&#46;</p><p id="par0205" class="elsevierStylePara elsevierViewall">The enoyl-&#40;acyl carrier protein&#41; reductase &#40;ENRs&#41;&#44; an enzyme that belongs to the energy category&#44; was remarkably up-regulated in teliospores&#46; This is interesting because this protein catalyzes the last step of the elongation cycle in the synthesis of fatty acids&#44; whose biosynthesis is essential for survival in mammals&#44; plants&#44; fungi and bacteria<a class="elsevierStyleCrossRef" href="#bib0275"><span class="elsevierStyleSup">19</span></a>&#46; The growing interest in ENRs is mainly due to the fact that a variety of antimicrobial compounds&#44; such as triclosan&#44; are shown to specifically target their activity&#46;</p><p id="par0210" class="elsevierStylePara elsevierViewall">The Ssp1 protein kinase &#40;MW691342&#41;&#44; identified as one of the down-regulated genes in the CF category&#44; plays a crucial role in facilitating the reorganization of the actin cytoskeleton following osmotic stress&#46; In <span class="elsevierStyleItalic">T&#46; frezii</span>&#44; its expression increased by 18-fold in the hyphal stage compared to the teliospore stage&#46; However&#44; in <span class="elsevierStyleItalic">U&#46; maydis</span>&#44; during the transition from the budding to the filamentous stage&#44; this increase was comparatively lower&#44; at only 4-fold<a class="elsevierStyleCrossRef" href="#bib0210"><span class="elsevierStyleSup">6</span></a>&#46; Putative Rer1 family protein &#40;MW691367&#41; is involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment&#46; In <span class="elsevierStyleItalic">T&#46; frezii</span>&#44; this gene expression was 5&#46;13-fold decreased in teliospores&#44; while in <span class="elsevierStyleItalic">M&#46; haptotylum</span> knobs&#47;mycelium transition&#44; the down-expression was 1&#46;36<a class="elsevierStyleCrossRef" href="#bib0185"><span class="elsevierStyleSup">1</span></a>&#46;</p><p id="par0215" class="elsevierStylePara elsevierViewall">Mart&#237;nez-Soto et al&#46;<a class="elsevierStyleCrossRef" href="#bib0270"><span class="elsevierStyleSup">18</span></a>&#44; found many genes differentially expressed in the transition between spore and hyphae in <span class="elsevierStyleItalic">U&#46; maydis</span>&#44; particularly&#44; three genes&#44; two of which were up-regulated and one was down-regulated&#58; probable adenosylhomocysteinase &#40;MW691399&#41;&#44; probable SMC2 &#8211; chromosome segregation protein &#40;MW691373&#41; and pacC &#8211; transcription factor pacC &#40;MW691404&#41; &#40;2 &#40;up&#41;&#59; 10&#46;3 &#40;up&#41; and 9&#46;2 &#40;down&#41; fold&#44; respectively&#41;&#46; <span class="elsevierStyleItalic">T&#46; frezii</span> orthologues genes were also differentially expressed and in the same direction &#40;up- or down-regulated&#41;&#46; Finally&#44; three other genes were up-regulated in the <span class="elsevierStyleItalic">U&#46; maydis</span> dimorphism<a class="elsevierStyleCrossRef" href="#bib0265"><span class="elsevierStyleSup">17</span></a>&#44; TPM2 &#40;tropomyosin isoform 2 &#40;MW691380&#41;&#44; a component of fungal filaments&#41;&#44; mitochondrial porin &#40;MW691376&#41; &#40;which allows the passage of small molecules across the mitochondrial outer membrane and is involved in complex interactions regulating organelle and cellular metabolism&#41; and CipC homolog &#40;MW691370&#41; &#40;5&#46;95&#59; 2&#46;25 and 14&#46;04-fold at protein level&#44; respectively&#41;&#46; Coincidentally&#44; we observed that the orthologues of these genes in <span class="elsevierStyleItalic">T&#46; frezii</span> were also up-regulated&#46;</p><p id="par0220" class="elsevierStylePara elsevierViewall">At least five uncharacterized proteins were differentially expressed in both <span class="elsevierStyleItalic">T&#46; frezii</span> and <span class="elsevierStyleItalic">U&#46; maydis</span>&#46; In the transition of <span class="elsevierStyleItalic">U&#46; maydis</span>&#44; the variation of the transcripts of the um10414 protein was 3&#46;5-fold increased&#59; a trend that was also observed in its orthologous protein in <span class="elsevierStyleItalic">T&#46; frezii</span>&#46; In contrast&#44; four other proteins&#44; um05276&#44; um10868&#44; um04575 and um10208 displayed down-regulation with fold changes of 11&#46;7&#59; 2&#46;7&#59; 2&#46;6 and 4&#46;7-fold decrease&#44; respectively&#46; Similarly&#44; the transcripts levels of their orthologous proteins in <span class="elsevierStyleItalic">T&#46; frezii</span> &#40;MW691418&#44; MW691421&#44; MW691424 and MW691425&#41; were also down-regulated&#46;</p><p id="par0225" class="elsevierStylePara elsevierViewall">In conclusion&#44; many cellular processes are involved in the morphological shifts from teliospores to hyphae of <span class="elsevierStyleItalic">T&#46; frezii</span>&#44; which makes it difficult to fully understand the intricacies of this complex process&#46; For this reason&#44; different approaches are necessary before we can explain this process at a molecular level&#46; Consequently&#44; we believe that our comprehensive analysis of the entire transcriptome during this transition serves as a fundamental step toward understanding this phenomenon and may lay the foundation for future studies of the molecular processes that occur during infection&#46;</p></span></span><span id="sec0100" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0125">Conflicts of interest</span><p id="par0230" class="elsevierStylePara elsevierViewall">The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper&#46;</p></span></span>"
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        5 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Introduction"
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        6 => array:3 [
          "identificador" => "sec0010"
          "titulo" => "Materials and methods"
          "secciones" => array:9 [
            0 => array:2 [
              "identificador" => "sec0015"
              "titulo" => "Collection&#44; isolation and cultivation of Thecaphora frezii"
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            1 => array:2 [
              "identificador" => "sec0020"
              "titulo" => "Nuclear staining of Thecaphora frezii hyphae"
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            2 => array:2 [
              "identificador" => "sec0025"
              "titulo" => "RNA extraction"
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              "identificador" => "sec0030"
              "titulo" => "Library preparation and RNA-Seq"
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              "titulo" => "RNA-Seq data analysis"
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              "titulo" => "T&#46; frezii differentially expressed genes from teliospore to hyphal stage"
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              "titulo" => "qPCR analysis of selected genes"
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          "titulo" => "Results"
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              "identificador" => "sec0065"
              "titulo" => "Identification of T&#46; frezii genes involved in the transition from teliospore to hyphae"
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              "identificador" => "sec0070"
              "titulo" => "Functional grouping of differentially expressed genes"
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              "titulo" => "qPCR analysis of selected genes"
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          "titulo" => "Discussions"
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              "titulo" => "Genes that code for proteins involved in metabolism"
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            1 => array:2 [
              "identificador" => "sec0090"
              "titulo" => "Genes involved in transport and cellular communication"
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            2 => array:2 [
              "identificador" => "sec0095"
              "titulo" => "Genes that code for proteins involved in CCDP&#44; CF&#44; CRDV&#44; DIC&#44; EN&#44; INNA&#44; PBF&#44; SDBCC and TPF"
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          "titulo" => "References"
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    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2023-01-30"
    "fechaAceptado" => "2023-10-31"
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          "clase" => "keyword"
          "titulo" => "Keywords"
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          "palabras" => array:5 [
            0 => "Teliospore"
            1 => "Hyphae"
            2 => "Transition"
            3 => "<span class="elsevierStyleItalic">Thecaphora frezii</span>"
            4 => "Peanut"
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          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec1839919"
          "palabras" => array:5 [
            0 => "Teliospora"
            1 => "Hifas"
            2 => "Cambio de estadio"
            3 => "<span class="elsevierStyleItalic">Thecaphora frezii</span>"
            4 => "Man&#237;"
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    "highlights" => array:2 [
      "titulo" => "Highlights"
      "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall"><ul class="elsevierStyleList" id="lis0005"><li class="elsevierStyleListItem" id="lsti0005"><span class="elsevierStyleLabel">&#8226;</span><p id="par0005" class="elsevierStylePara elsevierViewall">The transition of <span class="elsevierStyleItalic">Thecaphora frezii</span> from teliospore to hyphae is important in the life cycle&#46;</p></li><li class="elsevierStyleListItem" id="lsti0010"><span class="elsevierStyleLabel">&#8226;</span><p id="par0010" class="elsevierStylePara elsevierViewall">Analysis of RNAseq data made possible to observe genes up and down-regulated in fungal transition&#46;</p></li><li class="elsevierStyleListItem" id="lsti0015"><span class="elsevierStyleLabel">&#8226;</span><p id="par0015" class="elsevierStylePara elsevierViewall">Differential gene expressions can contribute to understand <span class="elsevierStyleItalic">Thecaphora frezii</span> biology&#46;</p></li></ul></p></span>"
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        "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Peanuts &#40;<span class="elsevierStyleItalic">Arachis hypogaea</span> L&#46;&#41; are among the most important leguminous crops in Argentina&#46; During the growing season&#44; they are frequently attacked by fungal diseases&#44; including <span class="elsevierStyleItalic">Thecaphora frezii</span>&#46; The spores of <span class="elsevierStyleItalic">T&#46; frezii</span> are structures that confer resistance to this phytopathogen&#46; The transition from teliospore to hypha is a characteristic process of some fungi&#44; which is essential for completing their life cycle&#46; Using the transcriptomes of teliospores and hyphae of <span class="elsevierStyleItalic">T&#46; frezii</span>&#44; we aimed to identify genes that were differentially expressed during this transition&#44; and we found 134 up-regulated and 66 down-regulated genes&#44; which would participate in different cellular processes such as&#58; &#40;a&#41; cell cycle and DNA processing&#59; &#40;b&#41; cell fate&#59; &#40;c&#41; rescue&#44; defense and cellular virulence&#59; &#40;d&#41; detoxification by CYP450&#59; &#40;e&#41; energy&#59; &#40;f&#41; nutrient interaction and nutritional adaptation&#59; &#40;g&#41; metabolism&#59; &#40;g&#41; proteins with binding functions or cofactor requirements&#59; &#40;h&#41; stress&#44; cell differentiation and biogenesis of cell components&#59; and &#40;i&#41; transport&#44; cell communication and transcription&#46; The identification of genes in <span class="elsevierStyleItalic">T&#46; frezii</span> and their expression levels during different stages of differentiation could contribute to our understanding of the biological mechanisms in this fungus&#46;</p></span>"
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        "resumen" => "<span id="abst0015" class="elsevierStyleSection elsevierViewall"><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">El man&#237; &#40;<span class="elsevierStyleItalic">Arachis hypogaea</span> L&#46;&#41; es uno de los cultivos leguminosos m&#225;s importantes de Argentina&#46; Durante el ciclo de siembra&#44; es atacado frecuentemente por enfermedades de origen f&#250;ngico&#44; entre ellos por <span class="elsevierStyleItalic">Thecaphora frezii</span>&#44; cuyas esporas son estructuras que le confieren resistencia a este fitopat&#243;geno&#46; El pasaje de teliospora a hifa es un proceso caracter&#237;stico de algunos hongos&#44; siendo fundamental para que el ciclo de vida se complete&#46; A partir de los transcriptomas de las teliosporas e hifas de <span class="elsevierStyleItalic">Thecaphora frezii</span> nos propusimos identificar aquellos genes que estuvieran diferencialmente expresados en este pasaje y encontramos 134 <span class="elsevierStyleItalic">up</span>-regulados y 66 <span class="elsevierStyleItalic">down</span>-regulados&#44; los cuales participar&#237;an en diferentes procesos celulares como son a&#41; ciclo mit&#243;tico y procesamiento del ADN&#59; b&#41; destino de la c&#233;lula&#59; c&#41; rescate&#44; defensa y virulencia celular&#59; d&#41; desintoxicaci&#243;n mediada por <span class="elsevierStyleItalic">CYP450</span>&#59; e&#41; energ&#237;a&#59; f&#41; interacci&#243;n de nutrientes y adaptaci&#243;n nutricional&#59; g&#41; metabolismo&#59; g&#41; prote&#237;nas con funciones de uni&#243;n o requerimiento de cofactores&#59; h&#41; estr&#233;s&#44; diferenciaci&#243;n celular y biog&#233;nesis de componentes celulares&#59; i&#41; transporte&#44; comunicaci&#243;n de las c&#233;lulas y transcripci&#243;n&#46; La identificaci&#243;n de genes de <span class="elsevierStyleItalic">Thecaphora frezii</span> y sus niveles de expresi&#243;n en distintos estadios de diferenciaci&#243;n podr&#237;an contribuir al conocimiento de mecanismos biol&#243;gicos presentes en este hongo&#46;</p></span>"
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        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Both authors contributed equally to this work&#46;</p>"
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            "apendice" => "<p id="par0245" class="elsevierStylePara elsevierViewall">The following are the supplementary data to this article&#58;<elsevierMultimedia ident="upi0005"></elsevierMultimedia><elsevierMultimedia ident="upi0010"></elsevierMultimedia><elsevierMultimedia ident="upi0015"></elsevierMultimedia></p>"
            "etiqueta" => "Appendix A"
            "titulo" => "Supplementary data"
            "identificador" => "sec0110"
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          "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Germination of teliospores in PDA plates&#46; &#40;A&#41; Germination and hyphae growth from teliospore after 5 days of incubation&#46; &#40;B&#41; Formation of mycelium after 10 days of incubation&#46; &#40;C&#41; Nuclear stain of hyphae with propidium iodide&#46; This dye binds to the genetic material and stains it in red&#46; The addition of RNAse in the staining process removes the RNA allowing the visualization of the nucleus only&#46;</p>"
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          "en" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Functional gene categorization &#40;&#37;&#41;&#46; &#40;1&#41; Cell cycle and DNA processing &#40;CCDP&#41;&#59; &#40;2&#41; cell fate &#40;CF&#41;&#59; &#40;3&#41; cell rescue&#44; defense and virulence &#40;CRDV&#41;&#59; &#40;4&#41; detoxification involving CYP450 &#40;DIC&#41;&#59; &#40;5&#41; energy &#40;EN&#41;&#59; &#40;6&#41; interaction of nutrients and nutritional adaptation &#40;INNA&#41;&#59; &#40;7&#41; metabolism &#40;ME&#41;&#59; &#40;8&#41; protein with binding function or cofactor requirement &#40;PBF&#41;&#59; &#40;9&#41; stress&#44; cell differentiation and biogenesis of cellular components &#40;SDBCC&#41;&#59; &#40;10&#41; transport and cellular communication &#40;TCC&#41;&#59; &#40;11&#41; transcription &#40;TPF&#41;&#59; &#40;12&#41; unclassified &#40;UNCL&#41; proteins and &#40;13&#41; implicated in several metabolic pathways &#40;SW&#41;&#46;</p>"
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        "etiqueta" => "Figure 3"
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          "en" => "<p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Expression of some differentially expressed genes quantified by real-time PCR&#46; Heatmap is showing differential gene expression between hyphae &#40;H1&#44; H2&#44; and H3 replicates&#41; and teliospores &#40;T1&#44; T2&#44; and T3 replicates&#41;&#46; Red and blue shadings represent higher and lower relative expression levels&#44; respectively&#46; Genes have been grouped based on their pattern of gene expression&#46; Actin transcript was used as a reference gene for expression normalization&#46;</p>"
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          "leyenda" => "<p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">T&#58; teliospore&#59; H&#58; hypha&#46;</p>"
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                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Gene description&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Fold changeT<span class="elsevierStyleHsp" style=""></span>&#8594;<span class="elsevierStyleHsp" style=""></span>H &#40;times&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">MW691228&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">Uricase&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">92&#46;50 UP&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">Haloacid dehalogenase-like hydrolase&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">85&#46;75 UP&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="center" valign="\n
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                  \t\t\t\t">Catalase&#47;peroxidase HPI&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Related to ADH6 &#8211; NADPH-dependent alcohol dehydrogenase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">51&#46;26 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691233&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative formate dehydrogenase &#40;NAD&#43;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">32&#46;16 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691234&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative phosphomannomutase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">31&#46;51 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691235&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative sterol C-24 reductase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">23&#46;02 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691236&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Glutaminase A&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">19&#46;74 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691237&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">K homology RNA-binding domain&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">17&#46;49 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691238&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative adenylosuccinate synthase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">15&#46;40 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691239&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Cytochrome-c peroxidase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">14&#46;08 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691240&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Acetyl-CoA synthetase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">14&#46;03 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691241&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Related to deacetylase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">13&#46;51 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691242&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Related to b2-aldehyde-forming enzyme&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">13&#46;11 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691243&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Glycosyltransferase family 1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">11&#46;28 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691244&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative alanine&#47;arginine aminopeptidase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">11&#46;09 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691245&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Short chain dehydrogenase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">10&#46;75 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691246&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative glycine decarboxylase subunit P&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">10&#46;27 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691247&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative inositol polyphosphate kinase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">9&#46;95 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691248&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Glycosyltransferase family 20&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">9&#46;02 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691249&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">PTPLA-domain-containing protein&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">9&#46;00 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691250&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Nucleotide-binding domain of the sugar kinase&#47;HSP70&#47;actin&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&#46;84 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691251&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">FBP1 &#40;fructose-1&#44;6-bisphosphatase 1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&#46;76 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691252&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative bifunctional &#40;2E&#44;6E&#41;-farnesyl diphosphate synthase&#47;dimethylallyltranstransferase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&#46;75 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691253&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Glyceraldehyde 3-phosphate dehydrogenase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&#46;40 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691254&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative bifunctional purine biosynthetic protein ade1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&#46;16 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691255&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Asparagine synthase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7&#46;99 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691256&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">CoA-transferase family III&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7&#46;88 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691257&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative adenylyl-sulfate kinase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7&#46;72 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691258&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative pre-mRNA splicing factor prp1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7&#46;52 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691259&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative histidine biosynthesis trifunctional protein&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7&#46;42 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691260&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative xylulokinase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7&#46;31 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691261&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2-Methylcitrate dehydratase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7&#46;12 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691262&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Aspartate aminotransferase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#46;78 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691263&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative triose-phosphate isomerase TPI1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#46;29 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691264&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative molybdenum cofactor synthesis protein&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#46;27 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691265&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3-Hydroxy-3-methylglutaryl-CoA lyase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#46;21 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691266&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5-Formyltetrahydrofolate cyclo-ligase family&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#46;06 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691267&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#46;06 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691268&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Glycerol 2-dehydrogenase &#40;NADP&#40;&#43;&#41;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#46;87 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691269&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Probable UDP-galactopyranose mutase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#46;87 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691270&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">UTP-glucose-1-phosphate uridyltransferase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#46;72 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691271&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative fumarate reductase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#46;48 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691272&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Probable LYS12 &#40;homo-isocitrate dehydrogenase&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#46;43 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691273&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative aspartate aminotransferase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#46;42 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691274&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Conserved hypothetical protein&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#46;41 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691275&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">GLN1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#46;08 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691276&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">HOM6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#46;57 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691277&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Related to betaine lipid synthase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#46;37 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691278&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Uncharacterized protein&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#46;31 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691279&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">ILV5-ketol-acid reductoisomerase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#46;27 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691280&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Uncharacterized protein&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#46;04 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691281&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Fatty acid elongase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#46;56 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691282&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Aldo-keto reductase yakc &#91;NADP&#43;&#93;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#46;63 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691283&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Fer6 &#8211; related to ATP-binding cassette transporter protein&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#46;91 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691284&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Fer5 &#8211; related to N6-hydroxylysine acetyltransferase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#46;74 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691285&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&#8242;-AMP-activated protein kinase catalytic subunit alpha-2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&#46;21 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691286&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Peptide methionine sulfoxide reductase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#46;62 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691287&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Inositol phospholipid synthesis and fat-storage-inducing TM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&#46;56 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691288&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Related to 7alpha-cephem-methoxylase P8 chain&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&#46;33 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691289&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative carboxyl methyl esterase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">10&#46;48 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691290&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">UDP-glucose 6-dehydrogenase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">11&#46;96 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691291&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Sodium-independent sulfate anion transporter&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">16&#46;30 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691292&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Related to peroxisomal amine oxidase &#40;copper-containing&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">18&#46;86 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691293&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Pyridoxal 5&#8242;-phosphate synthase lyase subunit PdxS&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">20&#46;21 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab3573983.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Genes involved in metabolism&#46;</p>"
        ]
      ]
      4 => array:8 [
        "identificador" => "tbl0010"
        "etiqueta" => "Table 2"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at2"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">T&#58; teliospore&#59; H&#58; hypha&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">GenBank accession number&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Gene description&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Fold change T T<span class="elsevierStyleHsp" style=""></span>&#8594;<span class="elsevierStyleHsp" style=""></span>H &#40;times&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691294&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Mitogen-activated serine&#47;threonine-protein kinase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">65&#46;56 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691295&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Related to aquaporin&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">25&#46;79 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691296&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative monosaccharide transporter&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">17&#46;53 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691297&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative aldehyde dehydrogenase family 7 member A1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">16&#46;45 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691298&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative nicotinate-nucleotide diphosphorylase &#40;carboxylation&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">16&#46;08 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691299&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Probable MET22 &#8211; protein ser&#47;thr phosphatase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">13&#46;65 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691300&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Sugar transport protein&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">10&#46;66 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691301&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Aspartic protease&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">9&#46;34 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691302&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Cation efflux family&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&#46;28 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691303&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Mitochondrial carrier protein&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7&#46;84 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691304&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Mitochondrial carrier protein&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7&#46;82 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691305&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Transmembrane amino acid transporter protein&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7&#46;36 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691306&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative heat shock protein Hsp88&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7&#46;24 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691307&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Mitochondrial matrix Mmp37&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#46;46 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691308&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Conserved hypothetical ATP-binding protein&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#46;34 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691309&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Hexose transporter&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#46;29 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691310&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Major facilitator superfamily&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#46;27 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691311&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">ABC transporter&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#46;25 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691312&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Uncharacterized protein&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#46;37 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691313&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Rac1 GTP-binding protein&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#46;00 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691314&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Related to putative monooxygenase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#46;13 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691315&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Related to acetate kinase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#46;59 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691316&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Related to MDR1 &#8211; Mac1p interacting protein&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#46;55 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691317&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Probable monosaccharide transporter&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#46;70 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691318&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Uncharacterized protein&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#46;80 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691319&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Choline transporter-like protein 2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#46;22 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691320&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Autophagy-related protein 8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#46;37 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691321&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Related to opsin-1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#46;96 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691322&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Uncharacterized protein&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&#46;39 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691323&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">SNF7 family protein&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&#46;88 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691324&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">ESCRT-III subunit protein SNF7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7&#46;10 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691325&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">RasGEF domain&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7&#46;47 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691326&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Derlin-2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7&#46;49 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691327&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative ATP-binding cassette glutathione S-conjugate transporter&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7&#46;80 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691328&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative GTP-binding protein ypt5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&#46;36 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691329&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative vacuolar ATP synthase subunit D&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&#46;99 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691330&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative iron-Sulfur cluster nifU-like protein&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">16&#46;20 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691331&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Lysine-specific permease&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">17&#46;02 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691332&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Plasma membrane P-type ATPase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">19&#46;67 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691333&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Amino acid permease&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">35&#46;90 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691334&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Probable ZRT2 &#8211; zinc transporter II&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">37&#46;81 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab3573985.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Genes involved in transport and cellular communication&#46;</p>"
        ]
      ]
      5 => array:8 [
        "identificador" => "tbl0015"
        "etiqueta" => "Table 3"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at3"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">CCDP&#58; cell cycle and DNA processing&#59; CF&#58; cell fate&#59; CRDV&#58; cell rescue&#44; defense and virulence&#59; DIC&#58; detoxification involving CYP450&#59; EN&#58; energy&#59; INNA&#58; interaction of nutrients and nutritional adaptation&#59; PBF&#58; protein with binding function or cofactor requirement&#59; SDBCC&#58; stress&#44; cell differentiation and biogenesis of cellular components&#59; TPF&#58; transcription&#59; T&#58; teliospore&#59; H&#58; hypha&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Category&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">GenBank accession number&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Gene description&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Fold change T<span class="elsevierStyleHsp" style=""></span>&#8594;<span class="elsevierStyleHsp" style=""></span>H &#40;times&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">CCDP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691335&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Clb2 &#40;b-type cyclin 2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#46;20 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">CCDP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691336&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Related to G1&#47;S-specific cyclin&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#46;73 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">CCDP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691337&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Related to DAD4 &#8211; outer kinetochore protein &#40;part of Dam1 complex&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#46;96 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">CCDP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691338&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Hus1-like protein&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#46;97 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">CCDP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691339&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">DNA repair protein RAD51 homolog 1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&#46;22 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">CCDP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691340&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative fimbrin&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">9&#46;37 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">CF&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691341&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Inhibitor of apoptosis-promoting Bax1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">17&#46;37 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">CF&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691342&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative dioxygenase Ssp1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">18&#46;32 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">CRDV&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691343&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">lon protease homolog 2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">36&#46;83 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">CRDV&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691344&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative chaperone ATPase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">27&#46;49 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">CRDV&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691345&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">HSP70&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">14&#46;27 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">CRDV&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691346&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Chitin synthase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">13&#46;01 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">CRDV&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691347&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Peroxisomal membrane protein&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7&#46;36 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">CRDV&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691348&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Taurine catabolism dioxygenase TauD&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">29&#46;24 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">DIC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691349&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Erg11 &#40;sterol 14 alpha-demethylase&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&#46;53 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">DIC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691350&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Cytochrome P450 94A1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#46;97 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">EN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691351&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative glutamate dehydrogenase&#44; NAD&#40;&#43;&#41;-specific&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">47&#46;90 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">EN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691352&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Enoyl-&#40;acyl carrier protein&#41; reductase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">27&#46;10 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">EN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691353&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Long-chain acyl-CoA synthetase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">21&#46;26 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">EN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691354&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative carnitine O-acetyltransferase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">11&#46;96 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">EN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691355&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative acetyl-CoA C-acyltransferase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">9&#46;46 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">EN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691356&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative acetyl-CoA C-acyltransferase precursor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&#46;42 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">INNA&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691357&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative neutral amino acid permease&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">9&#46;74 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">PBF&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691358&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Methylcrotonyl-CoA carboxylase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">12&#46;42 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">SDBCC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691359&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Related to CDC20 &#40;cell division control protein&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">25&#46;06 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">SDBCC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691360&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Root hair defective 3 GTP-binding protein&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#46;48 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">SDBCC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691361&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Related to YSC84 &#40;protein involved in the organization of actin cytoskeleton&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#46;99 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">SDBCC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691362&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Related to chitinase A precursor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#46;36 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">SDBCC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691363&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Related to GTP-binding protein Rab5c&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#46;98 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">TPF&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691364&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">S8 family peptidase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">13&#46;87 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">TPF&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691365&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Serine carboxypeptidase S28&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">11&#46;02 UP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">TPF&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691366&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">tRNA methyl transferase&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#46;53 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">TPF&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691367&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Putative Rer1 family protein&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&#46;13 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">TPF&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691368&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Uncharacterized protein&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&#46;69 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">TPF&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">MW691369&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Peptidase family M28&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="center" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">129&#46;88 DOWN&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
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          "en" => "<p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Genes involved in CCDP&#44; CF&#44; CRDV&#44; DIC&#44; EN&#44; INNA&#44; PBF&#44; SDBCC and TPF&#46;</p>"
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      "titulo" => "References"
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                    0 => array:2 [
                      "titulo" => "Comparison of gene expression in trap cells and vegetative hyphae of the nematophagous fungus <span class="elsevierStyleItalic">Monacrosporium haptotylum</span>"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:7 [
                            0 => "D&#46; Ahr&#233;n"
                            1 => "M&#46; Tholander"
                            2 => "C&#46; Fekete"
                            3 => "B&#46; Rajashekar"
                            4 => "E&#46; Friman"
                            5 => "T&#46; Johansson"
                            6 => "A&#46; Tunlid"
                          ]
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                    0 => array:2 [
                      "doi" => "10.1099/mic.0.27485-0"
                      "Revista" => array:5 [
                        "tituloSerie" => "Microbiology &#40;N Y&#41;"
                        "fecha" => "2005"
                        "volumen" => "151"
                        "paginaInicial" => "789"
                        "paginaFinal" => "803"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "First draft genome of <span class="elsevierStyleItalic">Thecaphora frezii</span>&#44; causal agent of peanut smut disease"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:9 [
                            0 => "R&#46;S&#46; Arias"
                            1 => "C&#46; Conforto"
                            2 => "V&#46;A&#46; Orner"
                            3 => "E&#46;J&#46; Carloni"
                            4 => "J&#46;H&#46; Soave"
                            5 => "A&#46;N&#46; Massa"
                            6 => "M&#46;C&#46; Lamb"
                            7 => "N&#46; Bernardi-Lima"
                            8 => "A&#46;M&#46; Rago"
                          ]
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                    0 => array:2 [
                      "doi" => "10.1186/s12863-023-01113-w"
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                        "tituloSerie" => "BMC Genom Data"
                        "fecha" => "2023"
                        "volumen" => "24"
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                      "titulo" => "Proteomic analysis of dimorphic transition in the phytopathogenic fungus <span class="elsevierStyleItalic">Ustilago maydis</span>"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "M&#46; B&#246;hmer"
                            1 => "T&#46; Colby"
                            2 => "C&#46; B&#246;hmer"
                            3 => "A&#46; Br&#228;utigam"
                            4 => "J&#46; Schmidt"
                            5 => "M&#46; B&#246;lker"
                          ]
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                    0 => array:2 [
                      "doi" => "10.1002/pmic.200600900"
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                        "tituloSerie" => "Proteomics"
                        "fecha" => "2007"
                        "volumen" => "7"
                        "paginaInicial" => "675"
                        "paginaFinal" => "685"
                        "link" => array:1 [
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                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17340586"
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                    0 => array:2 [
                      "titulo" => "<span class="elsevierStyleItalic">Thecaphora frezii</span> n&#46; sp&#46;&#44; par&#225;sita de <span class="elsevierStyleItalic">Arachis</span> sp"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46;M&#46; Carranza"
                            1 => "J&#46;C&#46; Lindquist"
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                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Bol Soc Argent Bot"
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                        "paginaInicial" => "11"
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                    0 => array:2 [
                      "titulo" => "Secreted aspartyl proteinase &#40;PbSap&#41; contributes to the virulence of <span class="elsevierStyleItalic">Paracoccidioides brasiliensis</span> infection"
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                          "etal" => false
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                            1 => "A&#46;F&#46;A&#46; Chaves"
                            2 => "M&#46;V&#46; Navarro"
                            3 => "P&#46;M&#46; Concei&#231;&#227;o"
                            4 => "K&#46;S&#46; Ferreira"
                            5 => "L&#46;S&#46; da Silva"
                            6 => "P&#46; Xander"
                            7 => "W&#46;L&#46; Batista"
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                      "doi" => "10.1371/journal.pntd.0006806"
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                        "tituloSerie" => "PLoS Negl Trop Dis"
                        "fecha" => "2018"
                        "volumen" => "12"
                        "paginaInicial" => "1"
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