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Vol. 40. Issue 2.
Pages 158-161 (April - June 2012)
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Vol. 40. Issue 2.
Pages 158-161 (April - June 2012)
Open Access
Manejo del síndrome de abstinencia por interrupción del baclofeno
Management Baclofen Withdrawal Syndrome
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Lisgelia Santanaa, Manuel Quinterob,
Corresponding author
manuequinteromd@yahoo.com

Autor para correspondencia: Departamento de Anestesiología, Facultad de Medicina, Universidad de Puerto Rico, P.O. Box 365067, 00936-5067 San Juan, Puerto Rico.
a Instructor, Clínica Intervencionista del Dolor, Universidad de Puerto Rico, San Juan, Puerto Rico
b Fellowship, Intervención en Dolor, Departamento de Anestesiología, Facultad de Medicina, Universidad de Puerto Rico, San Juan, Puerto Rico
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Resumen

La terapia con baclofeno intratecal es un tratamiento que puede aliviar algunos de los síntomas de la espasticidad severa. Actualmente, la infusión de baclofeno intratecal se utiliza principalmente para el manejo de la espasticidad asociada con parálisis cerebral, lesiones cerebrales o de columna vertebral, traumatismo craneoencefálico, encefalopatía anóxica, esclerosis múltiple, distonía, secuelas de accidente cerebrovascular y síndrome del hombre rígido, especialmente para los pacientes que no responden a otros tratamientos. Los pacientes pueden sufrir efectos secundarios en sistema nervioso central con este manejo, como consecuencia de un error de dosificación del baclofeno en la bomba. El cese repentino de la administración del baclofeno intratecal puede causar síntomas, que van desde leves hasta graves. Presentamos un caso de síndrome de abstinencia por baclofeno intratecal y su manejo exitoso en un paciente en que se desarrolló espasticidad severa.

Palabras clave:
Baclofeno
Síndrome de abstinencia de sustancias
Inyecciones espinales
Espasticidad muscular
Abstract

Intrathecal baclofen therapy is a treatment that can relieve some symptoms of severe spasticity. Currently intrathecal baclofen infusion is used primarily for spasticity associated with cerebral palsy, brain or spinal injury, traumatic brain injury, anoxic encephalopathy, multiple sclerosis, dystonia, stroke and stiff-man syndrome, particularly for those patients who are unresponsive. Patients can present central nervous system side effects, this can occur as a result of the pump delivering an incorrect dose of baclofen. Sudden cessation of Intrathecal baclofen administration can cause mild to severe symptoms. We report a case of Intrathecal baclofen withdrawal syndrome developing severe spasticity and its management.

Keywords:
Baclofen
Substance withdrawal syndrome
Spinal injections
Muscle spasticity
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Copyright © 2012. Sociedad Colombiana de Anestesiología y Reanimación
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