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Vol. 37. Issue 4.
Pages 356-372 (November - January 2010)
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Vol. 37. Issue 4.
Pages 356-372 (November - January 2010)
ARTÍCULO DE REVISIÓN
Open Access
Manejo farmacológico del dolor neuropático
Pharmacological Management of Neuropathic Pain
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14095
Sandra Flórez*, Marta León**, Marcela Torres***, Felipe Reyes****, Juan Camilo Serpa****, Ana María Ríos****
* Anestesiólogo. Especialista en Dolor y Cuidado Paliativo. Grupo de Dolor y Cuidado Paliativo. Profesor Asistente, Universidad de la Sabana.
** Anestesiólogo. Especialista en Dolor y Cuidado Paliativo. Grupo de Dolor y Cuidado Paliativo. Profesor Asociado, Universidad de la Sabana.
*** Epidemióloga. Grupo de Dolor y Cuidado Paliativo, Universidad de la Sabana.
**** Internos Rotatorios, Facultad de Medicina, Universidad de la Sabana.
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SUMMARY

The prevalence of neuropathic pain requires proposals for management guidelines. In some cases, the degree of severity and the difficulty of treating this disorder has resulted in poor quality of life. In Europe, reported prevalence is 5%, and chronic postoperative pain ranges between 5% and 85%, depending on the type of surgery. The purpose of this paper is to review the pharmacological options for treating neuropathic pain depending on the pathophysiology, and suggest therapeutical approaches with medications available in Colombia, included or not in the Mandatory Health Plan.

Key words:
Pain
pain threshold
neuralgia
causalgia
therapeutics (Source: MeSH, NLM)
RESUMEN

El dolor neuropático es una patología cuya prevalencia requiere proponer guías de manejo. Su severidad y, en algunos casos, dificultad para el tratamiento deterioran la calidad de vida. La prevalencia reportada en Europa es del 5%, y en dolor crónico post-operatorio varía entre 5 y 85% dependiendo del tipo de cirugía. El objetivo del presente artículo es revisar las alternativas farmacológicas para el manejo de dolor neuropático de acuerdo con su fundamento fisiopatológico, y presentar sugerencias para el manejo con medicamentos disponibles en Colombia, incluidos y no incluidos en el Plan Obligatorio de Salud.

Palabras clave:
dolor
umbral del dolor
neuralgia
causalgia
terapéutica. (Fuente: DeCS, BIREME)
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