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RESUMEN
La dexmedetomidina se usó para sedación inicialmente en unidades de cuidados intensivos. Sin embargo, sus efectos sedantes, analgésicos y ansiolíticos sin alteración de la función ventilatoria, permiten ampliar su uso en cirugía como anestésico intravenoso. La literatura reporta su utilidad en poblaciones quirúrgicas definidas, pero aún faltan estudios que respalden su utilización en todos los escenarios de la anestesia total intravenosa (TIVA). El propósito de la actual revisión es describir el papel de la dexmedetomidina en la misma.
Materiales y métodosSe realizó la búsqueda de literatura en las bases de datos referenciales de PubMed, Medline, EMBASE, Cochrane y LILACS. Fue ampliada según la bibliografía encontrada en los artículos inicialmente revisados y analizados
Palabras clave::
Dexmedetomidina
anestesia intravenosa
receptores adrenérgicos alfa 2
agonistas adrenérgicos. (Fuente: DeCS, BIREME).
Key words:
Dexmedetomidine
anesthesia intravenous
receptors adrenergic alpha-2
adrenergic agonists. (Source: MeSH, NLM).
SUMMARY
Dexmedetomidine was used initially for sedation in intensive care units. However, because of its sedative, analgesic and anti-anxiety effects and the fact that it does not alter ventilatory function, its use may be expanded as an intravenous agent in surgery. There are reports in the literature about its effective use in specific surgical populations, although further studies are required in order to support its use in all situations where total intravenous anesthesia (TIVA) is applied. The purpose of this review is to describe the role of dexmedetomidine in this form of anesthesia.
Materials y methodsA literature search was conducted in PubMed, Medline, EMBASE, Cochrane and LILACS. The search was expanded based on the references found in the articles repor los autores; la búsqueda fue hecha bajo los términos MeSH incluidos en las palabras claves.
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