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Vol. 18. Issue 6.
Pages 316-323 (November - December 2011)
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Vol. 18. Issue 6.
Pages 316-323 (November - December 2011)
Open Access
Características clínicas y pronóstico a un año de pacientes con síndrome coronario agudo sin elevación del segmento ST y arterias coronarias sanas
Clinical characteristics and one year prognosis of patients with acute coronary syndrome without ST segment elevation and normal coronary arteries
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2049
Nilson López1,
Corresponding author
nilsonlopez@gmail.com

Correspondencia: Unidad de Cardiología, Hospital Pablo Tobón Uribe. Calle 78B No. 59-240, Medellín, Colombia. Teléfono: (574) 445 9000. Fax: (574) 445 9812.
, Carlos Tenorio2
1 Hospital Pablo Tobón Uribe, Medellín, Colombia
2 Clínica Cardiovascular Santa María, Medellín, Colombia
Gloria Franco
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Article information
Objetivo

Describir las características clínicas y el pronóstico de los pacientes con infarto sin elevación del segmento ST y arterias coronarias normales.

Métodos

Estudio de cohorte en pacientes con infarto sin elevación del segmento ST con enfermedad coronaria o arterias coronarias normales (sin enfermedad coronaria), en el que se compararon: forma de presentación, intervenciones y desenlaces a un año.

Resultados

Cada cohorte estuvo compuesta por 24 pacientes. El grupo de pacientes sin enfermedad coronaria fue más joven (56±10 años vs. 63±10 años, p=0,026) y tuvo mayor cantidad de mujeres (62% vs. 29%, p=0,02). El puntaje de riesgo TIMI fue mayor en el grupo con enfermedad coronaria (3,3 vs. 2,5, p=0,02); sin embargo, no se tradujo en coronariografías más tempranas (sin enfermedad coronaria 19±18 h vs. con enfermedad coronaria 27±21 h, p=0,18). El número de vasos enfermos en los pacientes con enfermedad coronaria fue 1,6 y se implantaron 2,04 stents en promedio; en 75% de los casos éstos fueron no medicados. La estancia hospitalaria fue significativamente mayor en el grupo con enfermedad coronaria (3,5±1,7 vs. 2,3±1,1, p=0,01). Los pacientes sin enfermedad coronaria mostraron mejor fracción de eyección (0,57±0,06 vs. 0,50±0,12) y menor número de defectos segmentarios de contractilidad (8 vs. 15 pacientes, p=0,03). No hubo diferencias en cuanto a mortalidad por causa cardiovascular (con enfermedad coronaria 1 caso, sin enfermedad coronaria 0 casos), necesidad de nueva coronariografía (con enfermedad coronaria 1 caso, sin enfermedad coronaria 0 casos) y rehospitalización por dolor torácico (6 casos en ambos grupos).

Conclusiones

La probabilidad de rehospitalización por dolor torácico, necesidad de nueva coronariografía y muerte no difirió entre los pacientes con infarto sin elevación del segmento ST con o sin enfermedad coronaria obstructiva.

Palabras clave:
angina inestable/epidemiología
angiografía coronaria
enfermedad de la arteria coronaria/epidemiología
enfermedad de la arteria coronaria/radiografía
estudios de seguimiento
infarto del miocardio/epidemiología
evaluación de procesos y resultados (atención de salud)
pronóstico
medición de riesgo
Objective

To describe the clinical characteristics and prognosis of patients with acute myocardial infarction without ST-segment elevation and normal coronary arteries.

Methods

Cohort study in patients with myocardial infarction without ST-segment elevation with coronary disease or with normal coronary arteries (without coronary disease), in which we compared clinical presentation, interventions and outcomes at one year.

Results

Each cohort consisted of 24 patients. The group of patients without coronary disease was younger (56±10 years vs. 63±10 years, p=0.026) and had more women (62% vs. 29%, p=0.02). The TIMI risk score was higher in the group with coronary heart disease (3.3 vs. 2.5, p=0.02); however, it did not result into earlier coronary angiography (without coronary disease 19±18 hours, vs. with coronary artery disease 27±21 hours, p=0.18). The number of diseased vessels in patients with coronary artery disease was 1.6 and 2.04 stents were implanted on average; in 75% of cases these were not medicated. Hospital stay was significantly higher in the group with coronary heart disease (3.5±1.7 vs. 2.3±1.1, p=0.01). Patients without coronary artery disease showed better ejection fraction (0.57±0.06 vs. 0.50±0.12) and lower number of segmental defects of contractility (8 vs. 15 patients, p=0.03). There were no differences in mortality from cardiovascular causes (1 case with coronary artery disease; without coronary disease 0 cases), need for new coronary angiography (1 patient with coronary artery disease, without coronary disease 0 cases), and rehospitalization due to chest pain (6 cases in both groups).

Conclusions

The probability of rehospitalization for chest pain, need for new coronary angiography and death did not differ between patients with infarction without ST-segment elevation with or without obstructive coronary disease.

Keywords:
angina
unstable/epidemiology
coronary angiography
coronary artery disease/ epidemiology
coronary artery disease/radiography
follow-up studies
myocardial infarction/ epidemiology
outcome and process assessment (health care)
prognosis
risk assessment
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Copyright © 2011. Sociedad Colombiana de Cardiología y Cirugía Cardiovascular
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