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Inicio Revista Colombiana de Psiquiatría Neutropenia aguda en un paciente con delírium tratado con quetiapina
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Vol. 39. Issue 2.
Pages 433-439 (June 2010)
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Vol. 39. Issue 2.
Pages 433-439 (June 2010)
Reporte de caso
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Neutropenia aguda en un paciente con delírium tratado con quetiapina
Acute Neutropenia in a Patient with Delirium Treated with Quetiapine
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Juan David Velásquez Tirado1,
Corresponding author
jdvelasqueztirado@gmail.com

Correspondencia: Juan David Velásquez Tirado, Facultad de Medicina, Universidad Pontificia Bolivariana, Calle 78B No.72A-109, Medellín, Colombia
, Lina María Escobar Gómez2
1 Médico psiquiatra. Especialista en psiquiatra de enlace. Profesor asociado de la Universidad Pontificia Bolivariana. Grupo de Investigación en Psiquiatría de Enlace (GIPE). Psiquiatra de enlace, Clínica Universitaria Bolivariana. Medellín, Colombia
2 Médica psiquiatra. Hospital Universitario San Vicente de Paúl. Medellín, Colombia
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Resumen
Introducción

La neutropenia es reconocida como un efecto adverso observado con los medicamentos antipsicóticos, principalmente la clozapina. Aunque rara, la administración de quetiapina puede llevar a la aparición de este efecto adverso con altas tasas de morbimortalidad.

Objetivo

Describir un caso de neutropenia asociada con el uso de quetiapina en un paciente con delírium, quien posteriormente con la suspensión del medicamento presenta la resolución del cuadro.

Método

Reporte de caso de un hombre de 38 años de edad.

Resultado y conclusiones

Aun cuando el riesgo de neutropenia asociado con quetiapina es relativamente bajo, es importante la implementación rutinaria de un cuadro hemático tanto al inicio de la administración de quetiapina como de manera periódica. Siempre que sea posible se debe evitar combinar quetiapina con medicamentos con reconocida asociación con neutropenia.

Palabras clave:
quetiapina
neutropenia
efectos adversos
Abstract
Introduction

Neutropenia is a side effect of the use of antipsychotic drugs, mainly clozapine. Although rare, the administration of quetiapine may lead to the development of this adverse effect with high rates of morbidity and mortality.

Objective

To describe a case of neutropenia associated with the use of quetiapine in a patient with delirium and its subsequent resolution when the medication was withdrawn.

Method

Case report.

Results and conclusions

Although the risk of neutropenia associated with the use of quetiapine is relatively low, it is important to implement routine hemograms at the beginning of the treatment with quetiapine, and on a regular basis. Whenever possible, combinations of quetiapine and other drugs with netropenia as a recognized side effect must be avoided.

Key words:
Quetiapine
neutropenia
adverse effects
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Conflicto de interés: los autores manifiestan que no tienen ningún conflicto de interés en este artículo.

Copyright © 2010. Asociación Colombiana de Psiquiatría
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