Article information
Resumen
Las proteínas morfogénicas óseas (BMP: rhBMP-2 y rhBMP-7) se han introducido en el uso quirúrgico, durante los últimos años, para el tratamiento de las seudoartrosis de los huesos largos y en la artrodesis vertebral. Sin embargo, sus buenos resultados y el interés despertado han promovido numerosos trabajos experimentales y propuestas para aumentar sus indicaciones a otras enfermedades y situaciones. Analizar su coste, su eficacia, el transportador más adecuado para cada situación y la combinación con otros elementos es uno de los retos que tiene planteados la investigación en cirugía ortopédica.
Palabras clave:
BMP
BMP-7
Factores de crecimiento
Seudoartrosis
Hueso
Abstract
Bone morphogenetic protein (BMP: rhBMP-2 and rhBMP-7) have been introduced into the surgical use, in recent years, for the treatment of pseudoarthrosis of long bones and spinal fusion. However, its success and interest have promoted numerous experimental and proposals to increase its indications to other diseases and conditions. Analyze the cost, effectiveness, the carrier most appropriate for each situation and the combination with other elements is one of the challenges facing research in orthopedic surgery.
Keywords:
BMP
BMP-7
Growth factors
Pseudoarthrosis
Bone
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