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Revista Española de Cirugía Ortopédica y Traumatología (English Edition)
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Inicio Revista Española de Cirugía Ortopédica y Traumatología (English Edition) Brucellar knee arthritis: Report on two cases
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Vol. 54. Issue 2.
Pages 116-119 (March - April 2010)
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Vol. 54. Issue 2.
Pages 116-119 (March - April 2010)
Case report
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Brucellar knee arthritis: Report on two cases
Artritis brucelósica de rodilla: 2 casos clínicos
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C. Martín-Hernández
Corresponding author
cmartinh@salud.aragon.es

Corresponding author.
, J.J. Ballester-Jiménez, T. Espallargas-Doñate
Knee unit, Obispo Polanco Hospital, Teruel, Spain
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Abstract
Purpose

We present 2 cases of septic arthritis caused by brucella. The purpose of the study is to post a warning about a condition that may be unusual and difficult to diagnose but which should not go unnoticed.

Materials and methods

In both cases we performed plain films and blood tests. In the first case, we performed an MRi, serological and biochemical tests and synovial fluid cultures, which returned a negative result. Final diagnosis was made by means of an arthroscopic synovial tissue culture. No additional tests were carried out in the second case because it presented as an instance of acute septic arthritis. Diagnosis was made on the basis of a synovial fluid culture. After diagnosis, antibiotic treatment was initiated with rifampicin (300mg every 12h) and doxiciclin (100mg every 12 h) for at least 6 weeks.

Results

Healing occurred in both cases.

Conclusions

Brucellar septic arthritis is currently rather unusual in Western European countries. However, Spain and other countries in the Mediterranean region are still characterized by endemic levels of the disease. Brucellosis should invariably be included in the differential diagnosis of knee arthritis.

Keywords:
Brucella
Brucellosis
Septic arthritis
Knee
Resumen
Objetivo

Se presentan 2 casos de artritis séptica por Brucella. El objetivo es llamar la atención sobre una enfermedad que por ser de diagnóstico a veces difícil y cada vez menos frecuente no debe pasar desapercibida.

Material y método

En ambos casos se realizó radiología simple y analítica hemática. En el primer caso se realizó resonancia magnética, serología, bioquímica y cultivos de líquido sinovial, que fueron negativos. El diagnóstico definitivo se realizó mediante cultivo del tejido sinovial obtenido por artroscopia. En el segundo caso no se realizaron más pruebas complementarias por su presentación como artritis séptica aguda, y se realizó el diagnóstico por cultivo de líquido sinovial. Tras el diagnóstico, se inició pauta antibiótica con rifampicina (300mg cada 12h) y doxiciclina (100mg cada 12h) durante un mínimo de 6 semanas.

Resultados

En ambos casos se obtuvo la curación.

Conclusiones

La artritis séptica por Brucella es actualmente poco frecuente en los países de Europa occidental. Sin embargo, España y otros países de la zona mediterránea continúan presentando tasas endémicas de la enfermedad. La brucelosis debe incluirse en el diagnóstico diferencial de toda monoartritis de rodilla.

Palabras clave:
Brucella
Brucelosis
Artritis séptica
Rodilla
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References
[1.]
Informe anual de Enfermedades de Declaración Obligatoria; Centro Nacional de Epidemiología [accessed Feb 13 2009] Available from: http://www.isciii.es/htdocs/centros/epidemiologia/epi_informeanualEDO.jsp
[2.]
A. Pourbagher, M.A. Pourbagher, L. Savas, T. Turunc, Y.Z. Demiroglu, I. Erol, et al.
Epidemiologic, clinical, and imaging findings in brucellosis patients with osteoarticular involvement.
Am J Roentgenol, 187 (2006), pp. 873-880
[3.]
M. Bosilkovski, L. Krteva, M. Dimzova, I. Kondova.
Brucellosis in 418 patients from the Balkan Peninsula: Exposure-related differences in clinical manifestations, laboratory test results, and therapy outcome.
Int J Infect Dis, 11 (2007), pp. 342-347
[4.]
N. Zaks, S. Sukenik, M. Alkan, D. Flusser, L. Neumann, D. Buskila.
Musculoskeletal manifestations of brucellosis: A study of 90 cases in Israel.
Semin Arthritis Rheum, 25 (1995), pp. 97-102
[5.]
M.C. Gómez, J.A. Nieto, C. Rosa, P. Guijo, M.A. Escribano, A. Muñoz, et al.
Evaluation of seven tests for diagnosis of human brucellosis in an area where the disease is endemic.
Clin Vaccine Immunol, 15 (2008), pp. 1031-1033
[6.]
M. Cairó, E. Calbo, L. Gómez, A. Matamala, J. Asunción, E. Cuchi, et al.
Foreign-body osteoarticular infection by Brucella melitensis: A report of three cases.
J Bone Joint Surg Am, 88 (2006), pp. 202-204
[7.]
Y. Taflova, N. Salto€lu, G. Sahin, H.S. Aksu.
Osteoarthricular involvement of brucellosis in Turkey.
Clin Rheumatol, 18 (1999), pp. 214-219
[8.]
E. Ayafllio€lu, O. Ozlük, D. Kiliç, S. Kaygusuz, S. Kara, G. Aydin, et al.
A case of brucellar septic arthritis of the knee with a prolonged clinical course.
Rheumatol Int, b25 (2005), pp. 69-71
[9.]
A.P. Andonopoulos, G. Asimakopoulos, E. Anastasiou, H.P. Bassaris.
Brucella arthritis.
Scand J Rheumatol, 15 (1986), pp. 377-380
[10.]
P. Wernaers, F. Handelberg.
Brucellar arthritis of the knee: A case report with delayed diagnosis.
Acta Orthop Belg, 73 (2007), pp. 795-798
[11.]
J. Solera, E. Martínez-Alfaro, L. Sáez.
Meta-analysis of the efficacy of the combination of +rifampicin and doxycycline in the treatment of human brucellosis.
Med Clin (Barc), 102 (1994), pp. 731-738
Copyright © 2010. Sociedad Española de Cirugía Ortopédica y Traumatología (SECOT). All rights reserved
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