metricas
covid
Buscar en
Revista Española de Cirugía Ortopédica y Traumatología (English Edition)
Toda la web
Inicio Revista Española de Cirugía Ortopédica y Traumatología (English Edition) Open fractures
Journal Information
Vol. 54. Issue 6.
Pages 399-410 (November - December 2010)
Share
Share
Download PDF
More article options
Vol. 54. Issue 6.
Pages 399-410 (November - December 2010)
Review article
Full text access
Open fractures
Fracturas abiertas
Visits
8004
J.M. Muñoz Vivesa,
Corresponding author
jmmuvi@gmail.com

Corresponding author.
, P. Caba Doussouxb, D. Martí i Garínc
a Traumatology Department, “Dr. Josep Trueta” University Hospital, Girona, Spain
b Traumatology Unit, “12 de Octubre” University Hospital, Madrid, Spain
c Traumatology Unit, Sabadell Hospital, Parc Taulí Health Corporation, Sabadell, Barcelona, Spain
This item has received
Article information
Abstract

A review is presented on the current status of open fracture treatments, and an attempt is made to clear up controversies and establish the basic principles of their current treatment.

The use of antibiotics in the initial treatment of open fractures is a well known concept, and the earlier they are given the greater is the reduction in the likelihood of infection. The more radical the debridement is, the lower the rate of infection. The fixation method of choice for open fractures of the diaphysis of the leg is the intramedullary nail. The use of external fixation should be limited to cases of multiple traumas. If the debridement has been exhaustive, a better result is obtained with the primary closure of the wound. The loss of soft tissue must be repaired as soon as possible and using the simplest but most efficient system on the orthoplastic ladder; secondary closure, free graft, rotational flap, free microvascularised flap.

Although some treatment guidelines are clear, each open fracture is different and must be adapted to each fracture and to each patient.

Keywords:
Open fracture
Antibiotic
Wound
Tibia
Intramedullary nail
Resumen

Se presenta una revisión del estado actual del tratamiento de las fracturas abiertas. Procurando despejar controversias y establecer los principios básicos de su tratamiento actual.

El empleo de antibióticos en el tratamiento inicial de las fracturas abiertas es un concepto bien establecido, cuanto más precoz es su administración mayor es la reducción de la posibilidad de infección. Cuanto más radical es el desbridamiento, menor es la tasa de infección. El método de fijación de elección para las fracturas abiertas de las diáfisis de la extremidad inferior es el enclavado endomedular. El uso de fijadores externos debería limitarse a los casos de politraumatismos. Si el desbridamiento ha sido exhaustivo, se obtiene un mejor resultado con el cierre primario de la herida. Se debe reparar la pérdida de partes blandas tan pronto como sea posible y mediante el uso del sistema más simple pero eficaz en la escalera ortoplástica: cierre secundario, injerto libre, colgajo rotacional, colgajo libre microvascularizado.

Aunque algunas pautas de tratamiento son claras, cada fractura abierta es distinta por lo cual el tratamiento debe ajustarse a cada fractura y a cada paciente.

Palabras clave:
Fractura abierta
Antibiótico
Herida
Tibia
Clavo endomedular
Full text is only aviable in PDF
References
[1.]
J.L. Villarreal, C. Salcedo.
Fracturas abiertas. Manual SECOT de Cirugía Ortopédica y Traumatología.
Editorial Panamerica, (2003),
[2.]
E.P. Dellinger, S.D. Miller, M.J. Wertz, M. Grypma, B. Droppert, P.A. Anderson.
Risk of infection after open fracture of the arm or leg.
Arch Surg, 123 (1988), pp. 1320-1327
[3.]
M.J. Patzakis, J.P. Harvey, D. Ivler.
The role of antibiotics in the management of open fractures.
J Bone Joint Surg Am, 56-A (1974), pp. 532-541
[4.]
R. Gustilo, J.T. Anderson.
Prevention of infection in the treatment of one thousand and twenty-five open fractures of long bones: retrospective and prospective analyses.
J Bone Joint Surg Am, 58-A (1976), pp. 453-458
[5.]
EAST Practice management Working Group. Practice management guideline parameters for prophylactic antibiotics in open fractures. [consultado 1/9/2010]. Disponible en http://www.east.org/tpg/openfrac.pdf. Cita electrónica.
[6.]
R.A. Gosselin, I. Roberts, W.J. Gillespie.
Antibiotics for preventing infection in open limb fractures.
Cochrane Database Syst Rev, (2004), pp. CD003764
[7.]
D. Robinson, E. On, N. Hadas, N. Halperin, S. Hofman, I. Boldur.
Microbiologic flora contaminating open fractures: its significance in the choice of primary antibiotic agents and the likelihood of deep wound infection.
J Orthop Traumatol, 3 (1989), pp. 283-286
[8.]
J. Lee.
Efficacy of cultures in the management of open fractures.
Clin Orthop Relat Res, 339 (1997), pp. 71-75
[9.]
H. Carsenti-Etesse, F. Doyon, N. Desplaces, O. Gagey, C. Tancrede, C. Pradier, et al.
Epidemiology of bacterial infection during management of open leg fractures.
Eur J Clin Microbiol Infect Dis, 18 (1999), pp. 315-323
[10.]
M.J. Patzakis, J. Wilkins.
Factors influencing infection rate in open fracture wounds.
Clin Orthop Relat Res, 243 (1989), pp. 36-40
[11.]
J.I. Sorger, P.G. Kirk, C.J. Ruhnke, S.H. Bjornson, M.S. Levy, J. Cockrin, et al.
Once daily, high dose versus divided, low dose gentamicin for open fractures.
Clin Orthop Relat Res, 366 (1999), pp. 197-204
[12.]
M.J. Patzakis, R.S. Bains, J. Lee, L. Shepherd, G. Singer, R. Ressler, et al.
Prospective, randomized, double-blind study comparing single-agent antibiotic therapy, ciprofloxacin, to combination antibiotic therapy in open fracture wounds.
J Orthop Trauma, 14 (2000), pp. 529-533
[13.]
K. Okike, T. Bhattacharyya.
Trends in the management of open fractures. A critical analysis.
J Bone Joint Surg Am, 88-A (2006), pp. 2739-2748
[14.]
E.P. Dellinger, E.S. Caplan, L.D. Weaver, M.J. Wertz, B.M. Droppert, N. Hoyt, et al.
Duration of preventive antibiotic administration for open extremity fractures.
Arch Surg, 123 (1988), pp. 333-339
[15.]
P.A. Ostermann, S.L. Henry, D. Seligson.
Value of adjuvant local antibiotic administration in therapy of open fractures. A comparative analysis of 704 consecutive cases.
Langenbecks Arch Chir, 378 (1993), pp. 32-36
[16.]
H.D. Moehring, C. Gravel, M.W. Chapman, S.A. Olson.
Comparison of antibiotic beads and intravenous antibiotics in open fractures.
Clin Orthop Relat Res, (2000), pp. 254-261
[17.]
R. Lange, A.W. Bach, S.T. Hansen, K.H. Johansen.
Open tibial fractures with associated vascular injuries: Prognosis for limb salvage.
J Traumatol, 25 (1985), pp. 203-207
[18.]
K. Johansen, M. Daines, T. Howey, D. Helfet, S.T. Hansen.
Objective criteria accurately predict amputation following lower extremity trauma.
J Traumatol, 30 (1990), pp. 568-572
[19.]
E.J. MacKenzie, M.J. Bosse, J.F. Kellam, A.R. Burgess, L.X. Webb, M.F. Swiontkowski, LEAP Study Group, et al.
Factors influencing the decision to amputate or reconstruct after high-energy lower extremity trauma.
J Traumatol, 52 (2002), pp. 641-649
[20.]
J.W. Busse, C.L. Jacobs, M.F. Swiontkowski, M.J. Bosse, M. Bhandari, Evidence-Based Orthopaedic Trauma Working Group.
Complex limb salvage or early amputation for severe lower-limb injury: a meta-analysis of observational studies.
J Orthop Traumatol, 21 (2007), pp. 70-76
[21.]
B.D. Owens, J.C. Wenke.
Early wound irrigation improves the ability to remove bacteria.
J Bone Joint Surg Am, 89-A (2007), pp. 1723-1726
[22.]
K. Kindsfater, E.A. Jonassen.
Osteomyelitis in grade II and III open tibia fractures with late debridement.
J Orthop Traumatol, 9 (1995), pp. 121-127
[23.]
J. Spencer, A. Smith, D. Woods.
The effect of time delay on infection in open long-bone fractures: a 5-year prospective audit from a district general hospital.
Ann R Coll Surg Engl, 86 (2004), pp. 108-112
[24.]
A. Adili, M. Bhandari, E.H. Schemitsch.
The biomechanical effect of high-pressure irrigation on diaphyseal fracture healing in vivo.
J Orthop Traumatol, 16 (2002), pp. 413-417
[25.]
J.O. Anglen.
Comparison of soap and antibiotic solutions for irrigation of lower limb open fracture wounds. A prospective, randomized study.
J Bone Joint Surg Am, 87-A (2005), pp. 1415-1422
[26.]
R.E. Scully, C.P. Artz, Y. Sako.
An evaluation of the surgeon's criteria for determining the viability of muscle during debridement.
Arch Surg, 73 (1956), pp. 1031-1035
[27.]
C.M. Hobbs, P.E. Watkins.
Evaluation of the viability of bone fragments.
J Bone Joint Surg Br, 83-B (2001), pp. 130-133
[28.]
P. Worloch, R. Slack, L. Harvey, R. Mawhinwy.
The prevention of infection in open fractures: anexperimental study of the effect of fracture stability.
Injury, 25 (1994), pp. 31-38
[29.]
M.E. Muller, S.M. Perren, M. Allgower.
Manual of internal fixation: techniques recommended by the AO group.
3rd ed., Springer-Verlag, (1990),
[30.]
P. Tornetta, M. Bergman, N. Watnik, G. Berkowitz, J. Steuer.
Treatment of grade IIIb open fractures: a prospective randomised comparison of external fixation and non reamed locked nailing.
J Bone Joint Surg Br, 76-B (1994), pp. 13-19
[31.]
M.B. Henley, J.R. Chapman, J. Agel, E.J. Harvey, A.M. Whorton, M.F. Swiontokowski.
Treatment of type IIIA and IIIB open fractures of the tibial shaft: aprospecive comparison of undreamed interlocking intramedullary nails and half-ficha external fixation.
J Orthop Traumatol, 12 (1998), pp. 1-7
[32.]
Y.K. Tu, C.H. Lin, J.I. Su, D.T. Hsu, R.J. Chen.
Unreamed interlocking nail versus external fixator for open type III tibia fractures.
J Traumatol, 39 (1995), pp. 361-367
[33.]
C.C. Edwards, S.C. Simmons, B.D. Browner, M.C. Weigel.
Severe open tibial fractures: results treating 202 injuries with external fixation.
Clin Orthop Relat Res, 230 (1988), pp. 98-115
[34.]
K.A. Alberts, G. Loohagen, H. Einarsdottir.
Open tibial fractures: faster union after undreamed nailing than after fixation.
Injury, 30 (1999), pp. 519-523
[35.]
P.V. Giannoudis, C. Papakostidis, C. Roberts.
A review of the management of open fractures of the tibia and femur.
J Bone Joint Surg Br, 88-B (2006), pp. 281-289
[36.]
H.C. Pape, M. Auf’m’Kolk, T. Paffrath, G. Regel, J.A. Sturm, H. Tscherne.
Primary intramedullary femur fixation in multiple trauma patients with associated lung contusion: a cause of posttraumatic ARDS?.
J Traumatol, 34 (1993), pp. 540-547
[37.]
P. Antich-Adrover, D. Marti-Garín, J. Murias-Álvarez, C. Puente-Alonso.
External fixation and secondary intramedullary nailing of open tibial fracture: a randomised, prospective trial.
J Bone Joint Surg Br, 79-B (1997), pp. 433-437
[38.]
P.A. Blachut, R.N. Meek, P.J. O’Brien.
External fixation and delayed intramedullary nailing of open fractures of the tibial shaft: a sequential protocol.
J Bone Joint Surg Am, 72-A (1990), pp. 729-735
[39.]
D.J. Maurer, R.L. Merkow, R.B. Gustilo.
Infection after intramedullary anilig of severe open tibial fractures initially treated with external fixation.
J Bone Joint Surg Am, 71-A (1989), pp. 835-838
[40.]
L.B. Bone, S. Kassman, P. Stegemann, J. France.
Prospective study of union rate of open tibial fractures treated with locked, undreamed intramedullary anils.
J Orthop Traumatol, 8 (1994), pp. 45-49
[41.]
L.H. Reichert, L.D. McCarthy, S.P.F. Hugues.
The acute response to intramedullary reaming.
J Bone Joint Surg Br, 77-B (1995), pp. 490
[42.]
M. Bhandari, G.H. Guyatt, M.F. Swiontkowski, E.H. Schemitsch.
Treatment of open fractures of the shaft of the tibia: a systematic overview and meta-analysis.
J Bone Joint Surg Br, 83-B (2001), pp. 62-68
[43.]
C.M. Court-Brown, M.M. McQueen, A.A. Quaba, J. Christie.
Locked intramedullary nailing of open tibial fractures.
J Bone Joint Surg Br, 73-B (1991), pp. 959-964
[44.]
J.F. Keating, P.J. O’Brien, P.A. Blachut, R.N. Meek, H.M. Broekhuyse.
Locking intramedullary nailing with and without reaming for open fractures of the tibial shaft: a prospective, randomized study.
J Bone Joint Surg Am, 79-A (1997), pp. 334-341
[45.]
A.M. Whorton, M.B. Henley.
The role of the fibula in open fractures of the tibial shaft with fractures of the ipsilateral fibula: indications and outcomes.
Orthopaedics, 21 (1998), pp. 1101-1105
[46.]
Y.K. Tu, C.Y. Yen, C.H. Ma, S.W. Yu, Y.C. Chou, M.S. Lee, et al.
Soft-tissue injury management and flap reconstruction for mangled lower extremities.
[47.]
L. Sirkin.
Fractures with soft tissue injuries.
Skeletal Trauma, pp. 367-428
[48.]
R. Sanders, M. Swiontkowski, J. Nunley, P. Spiegel.
The management of fractures with soft-tissue disruptions.
J Bone Joint Surg Am, 75-A (1993), pp. 778-789
[49.]
E.J. MacKenzie, M.J. Bosse, A.N. Pollak, L.X. Webb, M.F. Swiontkowski, J.F. Kellam, et al.
Long-term persistence of disability following severe lower-limb trauma. Results of a seven-year follow-up.
J Bone Joint Surg Am, 87-A (2005), pp. 1801-1809
[50.]
T.V. Ly, T.G. Travison, R.C. Castillo, M.J. Bosse, E.J. MacKenzie.
Ability of lower-extremity injury severity scores to predict functional outcome after limb salvage.
J Bone Joint Surg Am, 90-A (2008), pp. 1738-1743
[51.]
L.X. Webb, M.J. Bosse, R.C. Castillo, E.J. MacKenzie.
Analysis of surgeon-controlled variables in the treatment of limbthreatening type-III open tibial diaphyseal fractures.
J Bone Joint Surg Am, 89-A (2007), pp. 923-928
[52.]
C.G. Zalavras, R.E. Marcus, L.S. Levin, M.J. Patzakis.
Management of open fractures and subsequent complications.
J Bone Joint Surg Am, 89-A (2007), pp. 884-895
[53.]
R.B. Gustilo, R.L. Merkow, D. Templeman.
The management of open fractures.
J Bone Joint Surg Am, 72-A (1990), pp. 299-304
[54.]
M.J. Patzakis.
Management of open fractures and complications.
Instr Course Lect, 31 (1982), pp. 62-64
[55.]
T.R. Bowen, J.C. Widmaier.
Host classification predicts infection after open fracture.
Clin Orthop Relat Res, 433 (2005), pp. 205-211
[56.]
L.X. Webb, D. Laver, A. DeFranzo.
Negative pressure wound therapy in the management of orthopedic wounds.
Ostomy Wound Manage, 50 (2004), pp. 26-27
[57.]
B.T. Dedmond, B. Kortesis, K. Punger, J. Simpson, J. Argenta, B. Kulp, et al.
The use of negative-pressure wound therapy (NPWT) in the temporary treatment of soft-tissue injuries associated with high-energy open tibial shaft fractures.
J Orthop Traumatol, 21 (2007), pp. 11-17
[58.]
A.A. Quaba.
Planificación de la cirugía de tejidos blandos.
Tratamiento de las fracturas abiertas, pp. 185-198
[59.]
W.G. DeLong, C.T. Born, S.Y. Wei, M.E. Petrik, R. Ponzio, C.W. Schwab.
Aggressive treatment of 119 open fracture wounds.
J Traumatol, 46 (1999), pp. 1049-1054
[60.]
S. Gopal, P.V. Giannoudis, A. Murray, S.J. Matthews, R.M. Smith.
The functional outcome of severe, open tibial fractures managed with early fixation and flap coverage.
J Bone Joint Surg Br, 86-B (2004), pp. 861-867
[61.]
S. Gopal, S. Majumder, A.G. Batchelor, S.L. Knight, P. DeBoer, R.M. Smith.
Fix and flap: the radical orthopaedic and plastic treatment of severe open fractures of the tibia.
J Bone Joint Surg Br, 82-B (2000), pp. 959-966
[62.]
H.S. Byrd, G. Cierny, J.B. Tebbetts.
The management of open tibial fractures with associated soft-tissue loss: external ficha fixation with early flap coverage.
Plast Reconstr Surg, 68 (1981), pp. 73-82
[63.]
G. Cierny, H.S. Byrd, R.E. Jones.
Primary versus delayed soft tissue coverage for severe open tibial fractures. A comparison of results.
Clin Orthop Relat Res, 178 (1983), pp. 54-63
[64.]
M. Godina.
Early microsurgical reconstruction of complex trauma of the extremities.
Plast Reconstr Surg, 78 (1986), pp. 285-292
[65.]
A.N. Pollak, M.L. McCarthy, A.R. Burgess, The Lower Extremity Assessment Project (LEAP) Study Group.
Short-term wound complications after application of flaps for coverage of traumatic soft-tissue defects about the tibia.
J Bone Joint Surg Am, 82-A (2000), pp. 1681-1691
[66.]
M. Ueno, K. Yokoyama, K. Nakamura, M. Uchino, T. Suzuki, M. Itoman.
Early unreamed intramedullary nailing without a safety interval and simultaneous flap coverage following external fixation in type IIIB open tibial fractures: a report of four successful cases.
Copyright © 2010. Sociedad Española de Cirugía Ortopédica y Traumatología (SECOT)
Download PDF
Article options
es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos