Article
Revista Española de Medicina Nuclear e Imagen Molecular (English Edition)
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Axial PET (b), axial CT (c) and axial fused PET/CT (d) images showing <span class="elsevierStyleSup">68</span>Ga-DOTATOC intense focal uptake of new growing tissue behind the uterine body (indicated with an arrow on MIP).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Francesco Dondi, Domenico Albano, Francesco Bertagna, Raffaele Giubbini" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Francesco" "apellidos" => "Dondi" ] 1 => array:2 [ "nombre" => "Domenico" "apellidos" => "Albano" ] 2 => array:2 [ "nombre" => "Francesco" "apellidos" => "Bertagna" ] 3 => array:2 [ "nombre" => "Raffaele" "apellidos" => "Giubbini" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S2253654X20301001" "doi" => "10.1016/j.remn.2020.05.013" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2253654X20301001?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2253808920300860?idApp=UINPBA00004N" "url" => "/22538089/0000004000000005/v1_202108210518/S2253808920300860/v1_202108210518/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Interesting images</span>" "titulo" => "A rare case of diffuse and bilateral pulmonary uptake in <span class="elsevierStyleSup">18</span>F-FDG PET/CT scan" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "337" "paginaFinal" => "338" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "P. Oliván-Sasot, R. Sánchez-Vañó, P. Calvillo-Batllés, J. Belda Ramirez, P. Bello-Arques" "autores" => array:5 [ 0 => array:4 [ "nombre" => "P." "apellidos" => "Oliván-Sasot" "email" => array:1 [ 0 => "olivan_pat@gva.es" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "*" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "R." "apellidos" => "Sánchez-Vañó" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "P." "apellidos" => "Calvillo-Batllés" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] ] 3 => array:3 [ "nombre" => "J." "apellidos" => "Belda Ramirez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">d</span>" "identificador" => "aff0020" ] ] ] 4 => array:3 [ "nombre" => "P." "apellidos" => "Bello-Arques" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:4 [ 0 => array:3 [ "entidad" => "Servicio de Medicina Nuclear, Hospital Universitario de La Ribera, Alzira, Valencia, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Medicina Nuclear, Hospital Universitario y Politécnico La Fe, Valencia, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Servicio de Radiología, Hospital Universitario y Politécnico La Fe, Valencia, Spain" "etiqueta" => "c" "identificador" => "aff0015" ] 3 => array:3 [ "entidad" => "Servicio de Neumología, Hospital Arnau de Vilanova, Valencia, Spain" "etiqueta" => "d" "identificador" => "aff0020" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Un caso raro de captación pulmonar difusa y bilateral en <span class="elsevierStyleSup">18</span>F-FDG PET/TC" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 730 "Ancho" => 1750 "Tamanyo" => 126743 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Fig. " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">[<span class="elsevierStyleSup">18</span>F] FDG-PET / CT. A) MIP image (maximum intensity projection) of FDG-PET showing diffuse pulmonary hypermetabolism of decreasing intensity to the bases and homogeneous uptake in axial and extra axial bonerrow. No other significant metabolic findings suggestive of malignancy. B, C and D) Axial, coronal and sagittal plane of fusioned [<span class="elsevierStyleSup">18</span>F]FDG-PET/CT showing extensive areas of bilateral ground glass with predominantly apical radiopharmaceutical avidity (SUVmax 10.8). E, F and G) Axial, coronal and sagittal CT sections: extensive areas of ground glass and consolidations.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 66-year-old male was studied for febrile syndrome without apparent focus for 3 weeks. During his admission, a mild ground glass infiltrate appeared on the chest computed tomography (CT) scan, with no clinical or radiological response to antibiotic or steroidal treatment. Blood cultures, abdominal-pelvic CT, gastroscopy and colonoscopy were negative. Blood tests revealed anemia with an inflammatory pattern and elevated acute phase reactants (erythrocyte sedimentation rate and C-reactive protein).</p><p id="par0010" class="elsevierStylePara elsevierViewall">Initially, given the findings seen on CT, it was oriented as an interstitial disease. Given the poor evolution of the patient and the rapid deterioration, a positron emission tomography/CT (PET/ CT) with [<span class="elsevierStyleSup">18</span>F]fludeoxyglucose ([<span class="elsevierStyleSup">18</span>F]FDG) was performed 12 days after the chest CT scan, looking for a febrile focus or tumor of unknown origin. On PET/CT, intense diffuse pulmonary activity was observed, of greater intensity in the upper lung fields, which decreased in a decreasing way to the bases, over large areas of ground glass on CT. Additionally, a diffuse axial and extra-axial increase in bone marrow metabolism was observed (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>). There were no supra or infradiaphragmatic lymphadenopathy, or other metabolic findings suggestive of malignancy.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">A viral infectious process with bacterial superinfection was assessed as the first diagnostic option, without being able to rule out other less frequent causes such as: inflammatory disease, pulmonary toxicity or tumor infiltration.</p><p id="par0020" class="elsevierStylePara elsevierViewall">A lung and bone marrow biopsy were performed, guided by PET/CT findings, resulting on 70% undifferentiated carcinoma with an infiltrative alveolar pattern, with negative immunohistochemical markers for squamous carcinoma (p40) and adenocarcinoma (TTF-1), and with probable bone marrow infiltration (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>). Additionally, a lepidic growth was observed, consisting of tumor infiltration of the walls of the alveolus, without producing mass or occupying the alveolus itself. Therefore, in the CT image we observed a ground glass pattern, without a clear mass effect.</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0025" class="elsevierStylePara elsevierViewall">Finally, the patient died from complications derived from a newly established pancytopenia, which was attributed to neoplastic infiltration of the bone marrow.</p><p id="par0030" class="elsevierStylePara elsevierViewall">This histology is not included in the most recent WHO classification,<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> but cases of lung adenocarcinoma associated with a fibrous reaction have been described, and it raises two hypotheses: a growing tumor on a lung parenchyma with previous interstitial disease or a reaction of the lung parenchyma to neoplastic development.<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a></p><p id="par0035" class="elsevierStylePara elsevierViewall">Causes described in the literature as possible diffuse and bilateral pulmonary uptake are chemotherapy-induced pneumonitis, aspiration pneumonia, carcinomatous lymphangitis, acute respiratory distress syndrome, and idiopathic pulmonary fibrosis.<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> This case would add one more cause to the possible differential diagnosis of diffuse pulmonary uptake.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Oliván-Sasot P, Sánchez-Vañó R, Calvillo-Batllés P, Belda Ramirez J, Bello-Arques P. Un caso raro de captación pulmonar difusa y bilateral en <span class="elsevierStyleSup">18</span>F-FDG PET/TC. Rev Esp Med Nucl Imagen Mol. 2021;40:337–338.</p>" ] ] "multimedia" => array:2 [ 0 => array:8 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 730 "Ancho" => 1750 "Tamanyo" => 126743 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Fig. " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">[<span class="elsevierStyleSup">18</span>F] FDG-PET / CT. A) MIP image (maximum intensity projection) of FDG-PET showing diffuse pulmonary hypermetabolism of decreasing intensity to the bases and homogeneous uptake in axial and extra axial bonerrow. No other significant metabolic findings suggestive of malignancy. B, C and D) Axial, coronal and sagittal plane of fusioned [<span class="elsevierStyleSup">18</span>F]FDG-PET/CT showing extensive areas of bilateral ground glass with predominantly apical radiopharmaceutical avidity (SUVmax 10.8). E, F and G) Axial, coronal and sagittal CT sections: extensive areas of ground glass and consolidations.</p>" ] ] 1 => array:8 [ "identificador" => "fig0010" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 496 "Ancho" => 1750 "Tamanyo" => 255972 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0010" "detalle" => "Fig. " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Images at 4x (A) and 40x (B) in Papanicolau stain, where we can identify neoplastic cells with lax chromatin thickening the alveolar walls, without observing a mass or alveolus invasion, integrating into the walls of the tissue itself.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:3 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The 2015 World Health Organization Classification of Lung Tumors: Impact of Genetic, Clinical and Radiologic Advances snce the 2004 Classification" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "W.D. Travis" 1 => "E. Brambilla" 2 => "A.G. Nicholson" 3 => "Y. Yatabe" 4 => "J.H.M. Austin" 5 => "M.B. Beasley" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/JTO.0000000000000630" "Revista" => array:5 [ "tituloSerie" => "J Thorac Oncol" "fecha" => "2015" "volumen" => "10" "paginaInicial" => "1243" "paginaFinal" => "1260" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lung adenocarcinoma feigning an interstitial lung disease in a 30-year-old man" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "S. Casallo Blanco" 1 => "F. Marcos Sánchez" 2 => "L. Matías Salves" 3 => "A. Viana Alonso" 4 => "J. Celdrán Gil" 5 => "E. Núñez Cuerda" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.4321/s0212-71992007000600008" "Revista" => array:6 [ "tituloSerie" => "An Med Interna" "fecha" => "2007" "volumen" => "24" "paginaInicial" => "289" "paginaFinal" => "291" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17907901" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Diffuse pulmonary uptake on FDG-PET with normal CT diagnosed as intravascular large B-cell lymphoma: a case report and a discussion of the causes of diffuse FDG uptake in the lungs" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "T. Wagner" 1 => "D. Brechemier" 2 => "E. Dugert" 3 => "S. Le Guellec" 4 => "A. Julian" 5 => "A. Hitzel" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1102/1470-7330.2012.0002" "Revista" => array:6 [ "tituloSerie" => "Cancer Imaging" "fecha" => "2012" "volumen" => "12" "paginaInicial" => "7" "paginaFinal" => "12" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22275725" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/22538089/0000004000000005/v1_202108210518/S2253808921000501/v1_202108210518/en/main.assets" "Apartado" => array:4 [ "identificador" => "7927" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Interesting images" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/22538089/0000004000000005/v1_202108210518/S2253808921000501/v1_202108210518/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2253808921000501?idApp=UINPBA00004N" ]
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The Revista Española de Medicina Nuclear e Imagen Molecular (Spanish Journal of Nuclear Medicine and Molecular Imaging), was founded in 1982, and is the official journal of the Spanish Society of Nuclear Medicine and Molecular Imaging, which has more than 700 members.
The Journal, which publishes 6 regular issues per year, has the promotion of research and continuing education in all fields of Nuclear Medicine as its main aim. For this, its principal sections are Originals, Clinical Notes, Images of Interest, and Special Collaboration articles. The works may be submitted in Spanish or English and are subjected to a peer review process.
In 2009, it became the leading Spanish journal in the field of Medical Imaging on having an Impact Factor , awarded by the Journal Citation Reports.
Science Citation Index Expander, Medline, IME, Bibliomed, EMBASE/Excerpta Medica, Healthstar, Cancerlit, Toxine, Inside Conferences, Scopus
See moreThe Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years.
© Clarivate Analytics, Journal Citation Reports 2022
SRJ is a prestige metric based on the idea that not all citations are the same. SJR uses a similar algorithm as the Google page rank; it provides a quantitative and qualitative measure of the journal's impact.
See moreSNIP measures contextual citation impact by wighting citations based on the total number of citations in a subject field.
See moreRevista Española de Medicina Nuclear e Imagen Molecular (English Edition)
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