Article
Revista Española de Medicina Nuclear e Imagen Molecular (English Edition)
array:24 [ "pii" => "S2253808917301258" "issn" => "22538089" "doi" => "10.1016/j.remnie.2017.10.010" "estado" => "S300" "fechaPublicacion" => "2018-11-01" "aid" => "937" "copyright" => "Elsevier España, S.L.U. and SEMNIM" "copyrightAnyo" => "2017" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Rev Esp Med Nucl Imagen Mol. 2018;37:387-9" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 4 "formatos" => array:2 [ "HTML" => 2 "PDF" => 2 ] ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S2253654X17301336" "issn" => "2253654X" "doi" => "10.1016/j.remn.2017.09.001" "estado" => "S300" "fechaPublicacion" => "2018-11-01" "aid" => "937" "copyright" => "Elsevier España, S.L.U. y SEMNIM" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Rev Esp Med Nucl Imagen Mol. 2018;37:387-9" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 76 "formatos" => array:2 [ "HTML" => 46 "PDF" => 30 ] ] "es" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Imágenes de interés</span>" "titulo" => "Estadificación y seguimiento terapéutico en un paciente con sarcoma de Ewing mediante PET/TC con <span class="elsevierStyleSup">18</span>F-FDG" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "387" "paginaFinal" => "389" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Staging and follow-up of a Ewing sarcoma patient using <span class="elsevierStyleSup">18</span>F-FDG PET/CT" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figura 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1868 "Ancho" => 2506 "Tamanyo" => 223380 ] ] "descripcion" => array:1 [ "es" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Imágenes sagitales del componente TC de los estudios realizados. La traducción lítica de las lesiones por M1 óseas, en especial L1, se evidencia en el control tras 10 meses del diagnóstico (D) con tendencia a la esclerosis en el de los 16 meses (F) y cambios variables posteriores.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "J.R. Garcia, A. Castañeda, A. Morales La Madrid, P. Bassa, M. Soler, E. Riera" "autores" => array:6 [ 0 => array:2 [ "nombre" => "J.R." "apellidos" => "Garcia" ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Castañeda" ] 2 => array:2 [ "nombre" => "A." "apellidos" => "Morales La Madrid" ] 3 => array:2 [ "nombre" => "P." "apellidos" => "Bassa" ] 4 => array:2 [ "nombre" => "M." "apellidos" => "Soler" ] 5 => array:2 [ "nombre" => "E." "apellidos" => "Riera" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S2253808917301258" "doi" => "10.1016/j.remnie.2017.10.010" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2253808917301258?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2253654X17301336?idApp=UINPBA00004N" "url" => "/2253654X/0000003700000006/v3_201812190642/S2253654X17301336/v3_201812190642/es/main.assets" ] ] "itemSiguiente" => array:18 [ "pii" => "S225380891830017X" "issn" => "22538089" "doi" => "10.1016/j.remnie.2018.03.008" "estado" => "S300" "fechaPublicacion" => "2018-11-01" "aid" => "981" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Rev Esp Med Nucl Imagen Mol. 2018;37:390-1" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 9 "formatos" => array:2 [ "HTML" => 2 "PDF" => 7 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Interesting images</span>" "titulo" => "Unexpected breast metastasis from cutaneous melanoma on <span class="elsevierStyleSup">18</span>F-FDG PET/CT" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "390" "paginaFinal" => "391" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Inesperada metástasis mamaria de melanoma cutáneo en PET/TC con <span class="elsevierStyleSup">18</span>F-FDG" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1690 "Ancho" => 2000 "Tamanyo" => 337393 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Unexpected breast metastasis from melanoma in the right breast detected with <span class="elsevierStyleSup">18</span>F-FDG PET/CT. Coronal (A) and axial (B) <span class="elsevierStyleSup">18</span>F-FDG PET/CT fusion images and axial CT images (C) show a well-defined hypermetabolic nodular lesion in the upper outer quadrant. Ultrasound-guided fine needle aspiration of the breast lesion yielded malignant cytology. The patient underwent a lumpectomy and histopathology confirmed metastatic melanoma.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "N. Martínez-Amador, I. Martínez-Rodríguez, A. García-Castaño, J. Jiménez-Bonilla, R. Quirce, I. Banzo" "autores" => array:6 [ 0 => array:2 [ "nombre" => "N." "apellidos" => "Martínez-Amador" ] 1 => array:2 [ "nombre" => "I." "apellidos" => "Martínez-Rodríguez" ] 2 => array:2 [ "nombre" => "A." "apellidos" => "García-Castaño" ] 3 => array:2 [ "nombre" => "J." "apellidos" => "Jiménez-Bonilla" ] 4 => array:2 [ "nombre" => "R." "apellidos" => "Quirce" ] 5 => array:2 [ "nombre" => "I." "apellidos" => "Banzo" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S2253654X18300131" "doi" => "10.1016/j.remn.2018.03.001" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2253654X18300131?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S225380891830017X?idApp=UINPBA00004N" "url" => "/22538089/0000003700000006/v3_201812190625/S225380891830017X/v3_201812190625/en/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S2253808917302100" "issn" => "22538089" "doi" => "10.1016/j.remnie.2017.12.006" "estado" => "S300" "fechaPublicacion" => "2018-11-01" "aid" => "960" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Rev Esp Med Nucl Imagen Mol. 2018;37:384-6" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 8 "formatos" => array:2 [ "HTML" => 6 "PDF" => 2 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Interesting image</span>" "titulo" => "Ethmoidal and extranodal Burkitt lymphoma in a child with bilateral kidney Burkitt lymphoma lesions incidentally detected by <span class="elsevierStyleSup">18</span>F-FDG PET/CT" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "384" "paginaFinal" => "386" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Linfoma de Burkitt etmoidal y extranodal en un niño con lesiones renales bilaterales de linfoma de Burkitt detectadas por <span class="elsevierStyleSup">18</span>F-FDG PET/TC" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 2841 "Ancho" => 2083 "Tamanyo" => 299044 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Maximum intensity projection (MIP) showing increased FDG uptake suggestive of malignant lesions in the ethmoidal sinus, bilateral cervical lymphadenopathies, several bone lesions and cortical lesions in both kidneys (A). Axial non-contrast enhanced CT with no pathological findings (B), axial PET/CT fused images (C) and axial PET (D) before treatment showing anomalous FDG distribution within the renal cortex, with focal increased uptake in the cortex of the right kidney (in this axial slice) corresponding to lesions visible on MRI (F); concordance between the PET and MR lesions were confirmed in PET/MR fusion images (E).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Mattia Bonacina, Mattia Bertoli, Domenico Albano, Francesco Bertagna, Francesco Laffranchi, Raffaele Giubbini" "autores" => array:6 [ 0 => array:2 [ "nombre" => "Mattia" "apellidos" => "Bonacina" ] 1 => array:2 [ "nombre" => "Mattia" "apellidos" => "Bertoli" ] 2 => array:2 [ "nombre" => "Domenico" "apellidos" => "Albano" ] 3 => array:2 [ "nombre" => "Francesco" "apellidos" => "Bertagna" ] 4 => array:2 [ "nombre" => "Francesco" "apellidos" => "Laffranchi" ] 5 => array:2 [ "nombre" => "Raffaele" "apellidos" => "Giubbini" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S2253654X18300751" "doi" => "10.1016/j.remn.2018.04.002" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2253654X18300751?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2253808917302100?idApp=UINPBA00004N" "url" => "/22538089/0000003700000006/v3_201812190625/S2253808917302100/v3_201812190625/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Interesting images</span>" "titulo" => "Staging and follow-up of a Ewing sarcoma patient using <span class="elsevierStyleSup">18</span>F-FDG PET/CT" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "387" "paginaFinal" => "389" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "J.R. Garcia, A. Castañeda, A. Morales, P. Bassa, M. Soler, E. Riera" "autores" => array:6 [ 0 => array:4 [ "nombre" => "J.R." "apellidos" => "Garcia" "email" => array:1 [ 0 => "Jrgarcia@cetir.es" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Castañeda" ] 2 => array:2 [ "nombre" => "A." "apellidos" => "Morales" ] 3 => array:2 [ "nombre" => "P." "apellidos" => "Bassa" ] 4 => array:2 [ "nombre" => "M." "apellidos" => "Soler" ] 5 => array:2 [ "nombre" => "E." "apellidos" => "Riera" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Unidad Pet Cetir-Eresa, Servicio Oncología, Hospital Sant Joan de Deu, Esplugues de Llobregat, Barcelona, Spain" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Estadificación y seguimiento terapéutico en un paciente con sarcoma de Ewing mediante PET/TC con <span class="elsevierStyleSup">18</span>F-FDG" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1868 "Ancho" => 2498 "Tamanyo" => 219674 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Sagittal images of the CT component of the <span class="elsevierStyleSup">18</span>F-FDG PET/CT studies performed. Lytic involvement in bone, especially in L1, was shown in follow-up study 10 months after diagnosis (D), with transition to partial bone sclerosis at the 16-months study (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>F), and with variable outcome afterwards.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A case of a 10-year-old male patient with intermittent right low back pain, low-grade fever and asthenia for 2 months and diagnosed of Ewing sarcoma in right pelvis is presented. Patient was referred for an <span class="elsevierStyleSup">18</span>F-FDG PET/CT for initial staging of the disease, which confirmed a primary high metabolic activity in right iliac bone, as well as multiple bone metastases metabolically active with no significant morphological alteration seen on the CT (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A). Given the extended disease, treatment was implemented according to the GEIS-21 (Spanish Group of Sarcoma's Research) course for high-risk disease (two cycles of gemcitabine/docetaxel: GD).</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">An <span class="elsevierStyleSup">18</span>F-FDG PET/CT performed after induction chemotherapy was completed (three cycles), showed metabolic response in primary tumor and in bone metastases (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>B). Surgery of primary bone tumor was rejected due to the great morbidity of the procedure and the extensive bone involvement at diagnosis, and patient was subsequently submitted to two more chemotherapy cycles corresponding to induction chemotherapy, as well as consolidation radiation therapy in primary lesion (55.8<span class="elsevierStyleHsp" style=""></span>Gy), with subsequent maintenance chemotherapy (GD). Follow-up PET/CT performed after three cycles showed persistent local and distant metabolic response to therapy (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>C).</p><p id="par0015" class="elsevierStylePara elsevierViewall">Follow-up <span class="elsevierStyleSup">18</span>F-FDG PET/CT performed after six maintenance cycles showed multiple bone disease recurrence (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>D), and therefore salvage therapy with two cycles of cyclophosphamide, topotecan and vincristine (CTV) was implemented, and subsequently complete metabolic response was achieved on <span class="elsevierStyleSup">18</span>F-FDG PET/CT (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>E). After the sixth CTV cycle, <span class="elsevierStyleSup">18</span>F-FDG PET/CT revealed disease recurrence (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>F), and patient was therefore included in a clinical trial (abraxane). Two months later, <span class="elsevierStyleSup">18</span>F-FDG PET/CT revealed again complete metabolic response (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>G).</p><p id="par0020" class="elsevierStylePara elsevierViewall">Two months later, patient was admitted to hospital with impaired level of consciousness due to brain involvement, and bone marrow metastatic progression was seen on <span class="elsevierStyleSup">18</span>F-FDG PET/CT (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>H). Palliative radiation therapy was implemented and patient died two months later.</p><p id="par0025" class="elsevierStylePara elsevierViewall">Ewing sarcoma accounts for the 3% of pediatric malignancies, and it is more prevalent in males than in females, especially over the second decade of life. It has been reported that 20–25% of patients present with distant metastatic disease at diagnosis, to bone marrow and lungs, and skeleton is the most frequently involved site, accounting for 50% of patients with metastases.<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">1</span></a><span class="elsevierStyleSup">18</span>F-FDG PET/CT has shown a superior sensitivity as compared to bone scintigraphy for detection of bone marrow involvement and bone disruption, which are a disease feature, as well as to assess lung involvement all with one-step imaging modality.</p><p id="par0030" class="elsevierStylePara elsevierViewall">Imaging techniques are widely known to have limited usefulness for the assessment of treatment outcome in bone metatastases. Bone scintigraphy may reveal persistent osteogenic activity for a long time, and the “flare” phenomenon may prevent image interpretation. A lytic lesion that turns into a blastic one is the only way to consider treatment response on CT.<a class="elsevierStyleCrossRefs" href="#bib0025"><span class="elsevierStyleSup">2,3</span></a> Our case highlights the late detection of bone involvement on the CT component (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>D), as well as how morphological response to therapy may be difficult to ascertain, due to variable changes in disease outcome, even when only one metastatic lesion is selected (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>).</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0035" class="elsevierStylePara elsevierViewall">The availability of different treatment schemes make sequential studies needed in order to allow clinical follow-up of these patients and to better ascertain when therapeutic changes are necessary to implement the most adequate treatment as well as to minimize their side effects. Therefore clinical surveillance at 3 and 6 months after treatment implementation is advisable to better determine the need for imaging follow-up.<a class="elsevierStyleCrossRefs" href="#bib0025"><span class="elsevierStyleSup">2,3</span></a></p><p id="par0040" class="elsevierStylePara elsevierViewall">Our case illustrates the usefulness of sequential <span class="elsevierStyleSup">18</span>F-FDG PET/CT studies in disease outcome of patients with Ewing sarcoma to allow for the implementation of the adequate therapeutic choices and timing.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Garcia JR, Castañeda A, Morales A, Bassa P, Soler M, Riera E. Estadificación y seguimiento terapéutico en un paciente con sarcoma de Ewing mediante PET/TC con <span class="elsevierStyleSup">18</span>F-FDG. Rev Esp Med Nucl Imagen Mol. 2018;37:387–389.</p>" ] ] "multimedia" => array:2 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1872 "Ancho" => 2500 "Tamanyo" => 313836 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">(A) Initial staging <span class="elsevierStyleSup">18</span>F-FDG PET/CT study which confirmed a lytic lesion metabolically active, with aggressive permeative pattern and periosteal involvement in right iliac bone, as well as multiple bone metastases also metabolically active with no significant morphological alteration on the CT. (B) Follow-up study after three cycles of chemotherapy, which showed metabolic response in primary tumor and bone metastases. (C) Follow-up study after induction chemotherapy, consolidation radiation therapy in primary lesion, and two cycles of maintenance chemotherapy, which showed persistent metabolic response at local and distant levels. (D) Follow-up study after six maintenance cycles which showed multiple bone recurrence of the disease, with lytic component on CT in several sites. (E) Follow-up study after two cycles of salvage therapy, which showed complete metabolic response of multiple bone involvement. (F) Follow-up study after six cycles of salvage therapy, which showed again metabolic recurrence. (G) Follow-up study two months after patient entered clinical trial, which showed complete metabolic response. (H) Follow-up study four months after patient entered clinical trial, which showed bone marrow metastatic progression.</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1868 "Ancho" => 2498 "Tamanyo" => 219674 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Sagittal images of the CT component of the <span class="elsevierStyleSup">18</span>F-FDG PET/CT studies performed. Lytic involvement in bone, especially in L1, was shown in follow-up study 10 months after diagnosis (D), with transition to partial bone sclerosis at the 16-months study (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>F), and with variable outcome afterwards.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:3 [ 0 => array:3 [ "identificador" => "bib0020" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pediatric bone sarcoma: diagnostic performance of <span class="elsevierStyleSup">18</span>F-FDG PET/CT versus conventional imaging for initial staging and follow-up" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "N. Quartuccio" 1 => "J. Fox" 2 => "D. Kuk" 3 => "L.H. Wexler" 4 => "S. Baldari" 5 => "A. Cistaro" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.2214/AJR.14.12932" "Revista" => array:6 [ "tituloSerie" => "AJR Am J Roentgenol" "fecha" => "2015" "volumen" => "204" "paginaInicial" => "153" "paginaFinal" => "160" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25539251" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0025" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The role of <span class="elsevierStyleSup">18</span>F-FDG PET/CT in patients treated with neoadjuvant chemotherapy for localized bone sarcomas" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "E. Palmerini" 1 => "M. Colangeli" 2 => "C. Nanni" 3 => "S. Fanti" 4 => "E. Marchesi" 5 => "A. Paioli" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1007/s00259-016-3509-z" "Revista" => array:6 [ "tituloSerie" => "Eur J Nucl Med Mol Imaging" "fecha" => "2017" "volumen" => "44" "paginaInicial" => "215" "paginaFinal" => "223" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27645694" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0030" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Response to chemotherapy estimates by FDG PET is an important prognostic factor in patients with Ewing sarcoma" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A. Raciborska" 1 => "K. Bilska" 2 => "K. Drabko" 3 => "E. Michalak" 4 => "R. Chaber" 5 => "M. 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The Revista Española de Medicina Nuclear e Imagen Molecular (Spanish Journal of Nuclear Medicine and Molecular Imaging), was founded in 1982, and is the official journal of the Spanish Society of Nuclear Medicine and Molecular Imaging, which has more than 700 members. The Journal, which publishes 6 regular issues per year, has the promotion of research and continuing education in all fields of Nuclear Medicine as its main aim. For this, its principal sections are Originals, Clinical Notes, Images of Interest, and Special Collaboration articles. The works may be submitted in Spanish or English and are subjected to a peer review process. In 2009, it became the leading Spanish journal in the field of Medical Imaging on having an Impact Factor , awarded by the Journal Citation Reports.
Science Citation Index Expander, Medline, IME, Bibliomed, EMBASE/Excerpta Medica, Healthstar, Cancerlit, Toxine, Inside Conferences, Scopus
See moreThe Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years.
© Clarivate Analytics, Journal Citation Reports 2022
SRJ is a prestige metric based on the idea that not all citations are the same. SJR uses a similar algorithm as the Google page rank; it provides a quantitative and qualitative measure of the journal's impact.
See moreSNIP measures contextual citation impact by wighting citations based on the total number of citations in a subject field.
See moreRevista Española de Medicina Nuclear e Imagen Molecular (English Edition)
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