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Hallazgos en la PET/TC con 18F-FDG" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 684 "Ancho" => 1200 "Tamanyo" => 223915 ] ] "descripcion" => array:1 [ "en" => "Hematoxylin and eosin staining (A) showed a tumor composed of myofibroblastic spindle cells accompanied by an inflammatory infiltrate,<a class="elsevierStyleCrossRefs" href="#bib0005">1,2</a> and a low mitotic activity (less than 1/10 HPF). On immunohistochemical analysis (B) the tumor cells were positive for desmin, smooth muscle actin, and anaplastic lymphoma kinase (ALK). The alteration of the ALK gene (CD246) have generally been reported to have no effect on prognosis, local recurrence, distant metastasis and overall survival, although some studies have detected a tendency to a better prognosis.<a class="elsevierStyleCrossRef" href="#bib0015">3</a>" ] ] ] "textoCompleto" => "A 34-year-old male patient was found to have a left abdominal mass after incidentally detecting a hypochromic, microcytic anemia, alteration of blood coagulation and hypoalbuminemia. He also referred weight loss and occasional diarrhea. PET/CT showed a large, solid, well-delimitated lobulated mass in the left hypochondrium/lateral region (largest diameter was 18.1cm), located in the anterior pararenal space. It displaced the fourth part of the duodenum and the pancreas, it was in close relation to the descending colon and presented an intense, heterogeneous 18F-FDG uptake with a SUVmax of 9.74, imaging findings that suggested malignancy (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>).<elsevierMultimedia ident="fig0005"></elsevierMultimedia>The patient underwent partial colectomy, being inflammatory myofibroblastic tumor (IMT) the final pathologic diagnosis (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>).<elsevierMultimedia ident="fig0010"></elsevierMultimedia>IMT is a rare neoplasm of mesenchymal origin<a class="elsevierStyleCrossRef" href="#bib0015">3</a> and unknown etiology. Inflammation following minor trauma or surgery, immune-autoimmune conditions and previous infections have been proposed as potential causes.<a class="elsevierStyleCrossRefs" href="#bib0005">1,3</a>Clinical symptoms are unspecific, being often incidentally detected on imaging studies or during diagnostic evaluation for unexplained fever, weight loss or anemia.<a class="elsevierStyleCrossRef" href="#bib0015">3</a> Many of its features can be related to the production of inflammatory mediators such as cytokines and particularly interleukin-1.<a class="elsevierStyleCrossRefs" href="#bib0005">1,3</a>18F-FDG uptake will depend on the tumor cellularity, the biological behavior of its cells (nuclear atypia and proliferative index), the composition and proportion of inflammatory cells, and the extent of activation of those cells at the time of examination.IMTs have traditionally been classified as benign lesions,<a class="elsevierStyleCrossRef" href="#bib0010">2</a> even with reports of spontaneous regressions,<a class="elsevierStyleCrossRef" href="#bib0015">3</a> but they can be locally aggressive and present local recurrences, which are more common during the first year (though described up to 9 years after surgery). It has also been reported rare cases of distant metastases<a class="elsevierStyleCrossRef" href="#bib0015">3</a> and even progression to a true malignant tumor,<a class="elsevierStyleCrossRefs" href="#bib0005">1,3</a> so it is recommended to consider them as neoplasms with intermediate or low-grade malignant potential,<a class="elsevierStyleCrossRef" href="#bib0010">2</a> being complete resection the treatment of choice.<a class="elsevierStyleCrossRef" href="#bib0010">2</a> Anti-inflammatory therapy may be useful before surgery to down-size the tumor or in patients with recurrent or non-resectable tumors.18F-FDG PET/CT can be performed to evaluate the tumor and to search for other potential malignant lesions, as well as for treatment evaluation and follow-up,<a class="elsevierStyleCrossRef" href="#bib0010">2</a> which is crucial for early detection of tumor recurrences." "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "Please cite this article as: Díaz Silván A, Allende Riera A, Cabello García D, Vilahomat Hernández O, Martínez Gimeno E. Tumor miofibroblástico inflamatorio. Hallazgos en 18F-FDG PET/CT. Rev Esp Med Nucl Imagen Mol. 2019;38:190–191." ] ] "multimedia" => array:2 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1048 "Ancho" => 1700 "Tamanyo" => 142771 ] ] "descripcion" => array:1 [ "en" => "Axial 18F-FDG PET image (A) and fused axial, coronal and sagittal PET/CT images (B, C and D, respectively), without contrast administration, demonstrated an irregular radiotracer distribution in the abdominal mass, identifying two main hypometabolic areas located in its right upper and its lower aspects (arrows)." ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 684 "Ancho" => 1200 "Tamanyo" => 223915 ] ] "descripcion" => array:1 [ "en" => "Hematoxylin and eosin staining (A) showed a tumor composed of myofibroblastic spindle cells accompanied by an inflammatory infiltrate,<a class="elsevierStyleCrossRefs" href="#bib0005">1,2</a> and a low mitotic activity (less than 1/10 HPF). On immunohistochemical analysis (B) the tumor cells were positive for desmin, smooth muscle actin, and anaplastic lymphoma kinase (ALK). The alteration of the ALK gene (CD246) have generally been reported to have no effect on prognosis, local recurrence, distant metastasis and overall survival, although some studies have detected a tendency to a better prognosis.<a class="elsevierStyleCrossRef" href="#bib0015">3</a>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:3 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Inflammatory pseudotumor" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "L.D. Narla" 1 => "B. Newman" 2 => "S.S. Spottswood" 3 => "S. Narla" 4 => "R. Kolli" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Radiographics" "fecha" => "2003" "volumen" => "23" "paginaInicial" => "719" "paginaFinal" => "729" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Inflammatory myofibroblastic tumor: FDG PET/CT findings with pathologic correlation" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A. Dong" 1 => "Y. Wang" 2 => "H. Dong" 3 => "J. Gong" 4 => "C. Cheng" 5 => "C. Zuo" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Clin Nucl Med" "fecha" => "2014" "volumen" => "39" "paginaInicial" => "113" "paginaFinal" => "121" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Inflammatory pseudotumor: the great mimicker" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "M. Patnana" 1 => "A.B. Sevrukov" 2 => "K.M. Elsayes" 3 => "C. Viswanathan" 4 => "M. Lubner" 5 => "C.O. Menias" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "AJR Am J Roentgenol" "fecha" => "2012" "volumen" => "198" "paginaInicial" => "W217" "paginaFinal" => "W227" ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/22538089/0000003800000003/v1_201905020850/S225380891830051X/v1_201905020850/en/main.assets" "Apartado" => array:4 [ "identificador" => "47121" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Interesting image" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/22538089/0000003800000003/v1_201905020850/S225380891830051X/v1_201905020850/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S225380891830051X?idApp=UINPBA00004N"]

ISSN: 2253-8089

The Revista Española de Medicina Nuclear e Imagen Molecular (Spanish Journal of Nuclear Medicine and Molecular Imaging), was founded in 1982, and is the official journal of the Spanish Society of Nuclear Medicine and Molecular Imaging, which has more than 700 members. The Journal, which publishes 6 regular issues per year, has the promotion of research and continuing education in all fields of Nuclear Medicine as its main aim. For this, its principal sections are Originals, Clinical Notes, Images of Interest, and Special Collaboration articles. The works may be submitted in Spanish or English and are subjected to a peer review process. In 2009, it became the leading Spanish journal in the field of Medical Imaging on having an Impact Factor , awarded by the Journal Citation Reports.

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Impact factor

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Impact factor 2023

1.6

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Citescore 2023

1.1

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SJR 2023

0.208

SNIP

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SNIP 2023

0.273

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