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"apellidos" => "Guerrero Cancio" "email" => array:1 [ 0 => "mayka@infomed.sld.cu" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor0005" ] ] ] 2 => array:2 [ "nombre" => "M.D." "apellidos" => "Cordero Jiménez" ] 3 => array:2 [ "nombre" => "I.K." "apellidos" => "Álvarez Velázquez" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Departamento de Medicina Nuclear y Oncología, Centro de Investigaciones Médico Quirúrgicas, La Habana, Cuba" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Importancia de la gammagrafía de perfusión pulmonar en el trasplante de pulmón único" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 3049 "Ancho" => 2924 "Tamanyo" => 423609 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Pre- and post-transplant images. Patient 1.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">Lung perfusion scintigraphy (LPS) with <span class="elsevierStyleSup">99m</span>Tc-MAA is one of the studies indicated in patients undergoing lung transplantation<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1,2</span></a> since this study evaluates and quantifies relative pulmonary function thereby facilitating the selection of the organ to be transplanted. We present two patients with emphysema who underwent single lung transplantation, which is one of the treatment alternatives for this type of non-infectious disease.<a class="elsevierStyleCrossRefs" href="#bib0015"><span class="elsevierStyleSup">3,4</span></a> The patients underwent pretransplant perfusion scintigraphy with the aim of qualitatively and quantitatively evaluating relative pulmonary perfusion and decide the lung to be selected for surgery. Several months after surgery post-transplant LPS was requested for both patients by the attending pneumologists with the aim of evaluating the pulmonary perfusion of the transplanted organ.</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Case presentation</span><p id="par0010" class="elsevierStylePara elsevierViewall">Pretransplant LPS was performed with the administration of 111<span class="elsevierStyleHsp" style=""></span>MBq (3<span class="elsevierStyleHsp" style=""></span>mCi) of <span class="elsevierStyleSup">99m</span>Tc-MAA, which is the appropriate quantity to obtain high quality diagnostic images and minimize the exposure of adult lung transplant patients to ionizing radiation.<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a> Five hundred thousand particles were injected. The anterior and posterior static images (matrix 128<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>128, 1,000,000<span class="elsevierStyleHsp" style=""></span>counts per images) were immediately acquired after intravenous administration of the radiotacer with the patient in a supine position<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> in a double detector DST-Xli gamma camera.</p><p id="par0015" class="elsevierStylePara elsevierViewall">The first case was a 44-year-old woman showing a relation of relative function of 49% in the left lung and 51% in the right lung on pretransplant LPS, detecting diminished perfusion in the left lung which was the organ to undergo transplantation. Four months after surgery a new LPS was performed obtaining a relation of relative function of 70% for the transplanted organ and 30% for the right lung (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>).</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">The second case involved a 52-year-old man in whom LPS demonstrated a relation of relative function of 23% for the left lung and 77% for the right lung, which, together with the qualitative analysis of the images, concluded that the left lung should be transplanted. One year after surgery the LPS was repeated, obtaining a relation of relative function of 51% for the transplanted organ and 49% for the right lung. In this case excellent response to the lung graft was also observed (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>).</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Discussion</span><p id="par0025" class="elsevierStylePara elsevierViewall">Single lung transplantation is considered a therapeutic option in the case of non-infectious diseases. LPS with <span class="elsevierStyleSup">99m</span>Tc-MAA plays an important role in the quantitative and qualitative evaluation of relative perfusion function in both the selection of the organ to be transplanted and in the postoperative follow-up of the patient. Analysis of the results of the two patients studied in our hospital indicates that the preoperative scintigraphy in the first case obtained a homogeneous relative function for both lungs (49–51%), but the visual analysis concluded that the absolute function of the right lung, albeit better than the left, was very diminished. This was confirmed in the post-transplant study on observing that the relative function of the transplanted lung increased to 70% while that of the native organ fell to 30%, taking into account that the graft had better perfusion. In the second case, the right lung had a relative function of 77% in the preoperative study, which diminished to 49% after the transplant. This is because the right lung had better absolute function than that of the first case, being confirmed in the visual analysis of the image. In the post-transplant study, the function of the right lung was reduced because it compared regionally with that of the graft, achieving a relative perfusion of 51–49%. These results indicate that in both cases the lung function of the transplanted organ improved. Previous studies by Zophel et al.<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> demonstrated that LPS with <span class="elsevierStyleSup">99m</span>Tc-MAA was the method of choice in the quantification of lung perfusion in the preoperative context. Tsagkaropoulos et al.<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a> demonstrated that although the choice of the organ (left or right) in single lung transplants does not influence patient survival, the selection of the lung to be transplanted is always based on the results of a quantitative perfusion study. On the other hand, LPS with <span class="elsevierStyleSup">99m</span>Tc-MAA is a follow-up method which allows qualitative and quantitative evaluation of the quality of the lung transplant over time.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:8 [ 0 => array:2 [ "identificador" => "xres120478" "titulo" => "Abstract" ] 1 => array:2 [ "identificador" => "xpalclavsec107758" "titulo" => "Keywords" ] 2 => array:2 [ "identificador" => "xres120479" "titulo" => "Resumen" ] 3 => array:2 [ "identificador" => "xpalclavsec107759" "titulo" => "Palabras clave" ] 4 => array:2 [ "identificador" => "sec0005" "titulo" => "Introduction" ] 5 => array:2 [ "identificador" => "sec0010" "titulo" => "Case presentation" ] 6 => array:2 [ "identificador" => "sec0015" "titulo" => "Discussion" ] 7 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2011-04-29" "fechaAceptado" => "2011-07-05" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec107758" "palabras" => array:3 [ 0 => "Lung perfusion scintigraphy" 1 => "Albumin aggregated" 2 => "Lung transplantation" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec107759" "palabras" => array:3 [ 0 => "Gammagrafía de perfusión pulmonar" 1 => "Macroagregados de albumina" 2 => "Trasplante de pulmón" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Lung perfusion scintigraphy (LPS) with <span class="elsevierStyleSup">99m</span>Tc-MAA gives valuable information about patients who will undergo a single lung transplantation. This technique makes it possible to evaluate and quantify the relative function of both lungs to select the organ to be transplanted. Once the surgery has been performed, the LPS represents a diagnostic method to study the status of the transplanted organ. Two patients who underwent single lung transplantation were studied in our hospital. In both cases, a pre-operative LPS was performed before surgery for selection of the organ to be transplanted and the scintigraphy study was performed a few months after transplantation to establish the perfusion function of the transplanted lung.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">La gammagrafía de perfusión pulmonar con <span class="elsevierStyleSup">99m</span>Tc-MAA ofrece una valiosa información de los pacien-tes que van a someterse a trasplante de pulmón único. El empleo de esta técnica nos permite evaluar y cuantificar la función relativa de ambos pulmones para seleccionar el órgano a trasplantar. Una vez que se ha realizado la cirugía, la gammagrafía de perfusión pulmonar representa un método diagnóstico para evaluar la evolución del órgano trasplantado. Dos pacientes que fueron sometidos a este procedimiento quirúrgico fueron estudiados en nuestro hospital. En ambos se realizó gammagrafía de perfusión pulmo-nar preoperatoria para la selección del órgano a trasplantar, y meses después de la cirugía se realizó el estudio gammagráfico para la evaluación de la función de perfusión del órgano trasplantado.</p>" ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara">Please cite this article as: Rodríguez Mesa NV, et al. Importancia de la gammagrafía de perfusión pulmonar en el trasplante de pulmón único. Rev Esp Med Nucl. 2012;<span class="elsevierStyleBold">31(6)</span>:332–4.</p>" ] ] "multimedia" => array:2 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 3049 "Ancho" => 2924 "Tamanyo" => 423609 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Pre- and post-transplant images. Patient 1.</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 3069 "Ancho" => 2931 "Tamanyo" => 411150 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Pre- and post-transplant images. Patient 2.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:7 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Trasplante pulmonar: Criterios de selección y evaluación de candidatos" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "F. Santos Luna" 1 => "R. Lama Martinez" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "NEUMOSUR" "fecha" => "2000" "volumen" => "12" "paginaInicial" => "120" "paginaFinal" => "130" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ventilation/perfusion lung scintigraphy: what is still needed? 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Year/Month | Html | Total | |
---|---|---|---|
2019 January | 1 | 0 | 1 |
2018 February | 9 | 0 | 9 |
2018 January | 2 | 2 | 4 |
2017 December | 9 | 0 | 9 |
2017 November | 3 | 2 | 5 |
2017 October | 7 | 3 | 10 |
2017 September | 12 | 4 | 16 |
2017 August | 8 | 6 | 14 |
2017 July | 8 | 1 | 9 |
2017 June | 8 | 13 | 21 |
2017 May | 21 | 3 | 24 |
2017 April | 11 | 10 | 21 |
2017 March | 9 | 20 | 29 |
2017 February | 6 | 7 | 13 |
2017 January | 8 | 0 | 8 |
2016 December | 9 | 3 | 12 |
2016 November | 8 | 6 | 14 |
2016 October | 12 | 10 | 22 |
2016 September | 13 | 4 | 17 |
2016 August | 6 | 4 | 10 |
2016 July | 8 | 1 | 9 |
2016 June | 14 | 5 | 19 |
2016 May | 16 | 9 | 25 |
2016 April | 6 | 1 | 7 |
2016 March | 6 | 8 | 14 |
2016 February | 15 | 5 | 20 |
2016 January | 7 | 9 | 16 |
2015 December | 12 | 5 | 17 |
2015 November | 15 | 11 | 26 |
2015 October | 18 | 6 | 24 |
2015 September | 17 | 9 | 26 |
2015 August | 6 | 1 | 7 |
2015 July | 4 | 2 | 6 |
2015 June | 7 | 3 | 10 |
2015 May | 15 | 2 | 17 |
2015 April | 17 | 4 | 21 |
2015 March | 22 | 6 | 28 |
2015 February | 14 | 0 | 14 |
2015 January | 18 | 5 | 23 |
2014 December | 28 | 6 | 34 |
2014 November | 12 | 1 | 13 |
2014 October | 32 | 3 | 35 |
2014 September | 15 | 7 | 22 |
2014 August | 19 | 4 | 23 |
2014 July | 22 | 2 | 24 |
2014 June | 15 | 3 | 18 |
2014 May | 8 | 1 | 9 |
2014 April | 14 | 2 | 16 |
2014 March | 7 | 0 | 7 |
2014 February | 17 | 2 | 19 |
2014 January | 10 | 1 | 11 |
2013 December | 14 | 2 | 16 |
2013 November | 14 | 1 | 15 |
2013 July | 1 | 0 | 1 |
2013 June | 1 | 0 | 1 |
2013 May | 2 | 0 | 2 |