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The <span class="elsevierStyleSup">11</span>C-methionine PET showed cortico-subcortical lesion on the right parieto-temporal lobe without abnormal activity of the tracer, features suggestive of benign lesion. The stereotactic biopsy confirmed the existence of a DNET.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "J.R. García, M. Baquero, E. Llinares, M. Soler, M. Moragas, E. Riera" "autores" => array:6 [ 0 => array:2 [ "nombre" => "J.R." "apellidos" => "García" ] 1 => array:2 [ "nombre" => "M." "apellidos" => "Baquero" ] 2 => array:2 [ "nombre" => "E." "apellidos" => "Llinares" ] 3 => array:2 [ "nombre" => "M." "apellidos" => "Soler" ] 4 => array:2 [ "nombre" => "M." "apellidos" => "Moragas" ] 5 => array:2 [ "nombre" => "E." "apellidos" => "Riera" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S2253654X15000128" "doi" => "10.1016/j.remn.2015.02.005" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2253654X15000128?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2253808915000762?idApp=UINPBA00004N" "url" => "/22538089/0000003400000005/v1_201508130058/S2253808915000762/v1_201508130058/en/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S2253808915000853" "issn" => "22538089" "doi" => "10.1016/j.remnie.2015.07.011" "estado" => "S300" "fechaPublicacion" => "2015-09-01" "aid" => "671" "copyright" => "Elsevier España, S.L.U. and SEMNIM" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Rev Esp Med Nucl Imagen Mol. 2015;34:327-8" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 98 "formatos" => array:2 [ "HTML" => 12 "PDF" => 86 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Interesting images</span>" "titulo" => "An 18-year delay in the clinical presentation of bronchial carcinoid" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "327" "paginaFinal" => "328" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Retraso de 18 años en la presentación clínica de carcinoide bronquial" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 2334 "Ancho" => 1668 "Tamanyo" => 614710 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">(A) CT scan performed in 1996: the image evidences a round-shaped solid nodule (measuring 21<span class="elsevierStyleHsp" style=""></span>mm in the major axis) localized near to the apical bronchus of the right lower lobe. The clinical diagnosis was consistent with intrapulmonary lymph-node associated to tuberculosis. (B) CT scan performed 18 years after: CT slice demonstrates the enlargement of the lung nodule (26<span class="elsevierStyleHsp" style=""></span>mm in the major axis). (C) Whole body PET/CT performed 1<span class="elsevierStyleHsp" style=""></span>h after the administration of 296<span class="elsevierStyleHsp" style=""></span>MBq of <span class="elsevierStyleSup">18</span>FDG (axial, coronal and sagittal slices): the images evidenced an increased uptake of a round-shaped solid nodule of the right lower lobe (SUV max 4.7). No sign of mediastinal or extra-thoracic disease was disclosed.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Giovanni Leuzzi, Daniele Forcella, Enrico Melis, Paolo Visca, Francesco Facciolo" "autores" => array:5 [ 0 => array:2 [ "nombre" => "Giovanni" "apellidos" => "Leuzzi" ] 1 => array:2 [ "nombre" => "Daniele" "apellidos" => "Forcella" ] 2 => array:2 [ "nombre" => "Enrico" "apellidos" => "Melis" ] 3 => array:2 [ "nombre" => "Paolo" "apellidos" => "Visca" ] 4 => array:2 [ "nombre" => "Francesco" "apellidos" => "Facciolo" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2253808915000853?idApp=UINPBA00004N" "url" => "/22538089/0000003400000005/v1_201508130058/S2253808915000853/v1_201508130058/en/main.assets" ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Interesting image</span>" "titulo" => "<span class="elsevierStyleSup">99m</span>Tc-HDP SPECT/MRI in isolated xanthoma of the temporal bone" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "329" "paginaFinal" => "330" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "J.A. Lojo-Ramírez, F.J. García-Gómez, A. Kaen, F. Roldán, D. Marcilla-Plaza, I. Acevedo-Báñez" "autores" => array:6 [ 0 => array:4 [ "nombre" => "J.A." "apellidos" => "Lojo-Ramírez" "email" => array:1 [ 0 => "jalojoram@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "F.J." "apellidos" => "García-Gómez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 2 => array:3 [ "nombre" => "A." "apellidos" => "Kaen" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 3 => array:3 [ "nombre" => "F." "apellidos" => "Roldán" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] ] 4 => array:3 [ "nombre" => "D." "apellidos" => "Marcilla-Plaza" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">d</span>" "identificador" => "aff0020" ] ] ] 5 => array:3 [ "nombre" => "I." "apellidos" => "Acevedo-Báñez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:4 [ 0 => array:3 [ "entidad" => "Department of Nuclear Medicine, Universitary Hospital Virgen del Rocío, Seville, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Department of Neurosurgery, Universitary Hospital Virgen del Rocío, Seville, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Department of Radiology, Universitary Hospital Virgen del Rocío, Seville, Spain" "etiqueta" => "c" "identificador" => "aff0015" ] 3 => array:3 [ "entidad" => "Department of Pathology, Universitary Hospital Virgen del Rocío, Seville, Spain" "etiqueta" => "d" "identificador" => "aff0020" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "<span class="elsevierStyleSup">99m</span>Tc-HDP SPECT/RM en xantoma único del hueso temporal" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1491 "Ancho" => 3253 "Tamanyo" => 331021 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">(a) Whole body bone scintigraphy revealing an hypermetabolic focus in the right temporal region. (b, c) Planar lateral view and SPECT images of the skull revealed central photopenic area surrounded by rim of increased uptake. (d) Axial FLAIR-sequence MRI, images suggestive of an intradiploic epidermoid cyst of the temporal bone. (e) SPECT/MRI hybrid images.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 41-year-old male patient with a long history of migraine, was referred to our department for nonspecific groin pain. Bone scintigraphy revealed an incidental hypermetabolic focus located at right temporal bone (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>a and b). A fused <span class="elsevierStyleSup">99m</span>Tc-HDP SPECT/MRI was performed in order to improve the nature. SPECT images showed a well-defined increased uptake of radiotracer with annular shape and an osteoblastic rim uptake surrounding the lesion (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>c), in correlation with an intradiploic epidermoid cyst of the temporal bone observed in axial FLAIR-sequence MRI (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>d and e). Foamy macrophages with related spaces of preexisting cholesterol crystals and extensive foci of hemorrhage were observed in hystopathology (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>).</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">Intraosseous xanthoma is an extremely rare benign bone tumor<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">1</span></a> characterized as a lytic lesion, often with cortical expansion or disruption. To our knowledge, only 16 cases of temporal isolated xanthoma have been reported<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">2</span></a> but none of nuclear medicine imaging have been published up to date. Although they are benign in nature, intracranial xanthomas frequently progress and may cause cranial nerve deficits. They generally originate from hyperlipidemic and hypercholesterolemic diseases. In our case, hyperlipidemia was absent. From a clinical neurosurgical standpoint, xanthoma of bone is best regarded as a benign tumor of histiocytic origin stemming from bone marrow.</p><p id="par0015" class="elsevierStylePara elsevierViewall">Bone scintigraphy and SPECT images could be useful for mapping out the skeletal system. Because of its aggressive imaging appearance other primary bone tumors, metastatic involvement or xanthomatous diseases (Histiocytoma, Erdheim-Chester or Rosai-Dorfman diseases) need to be ruled out.<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">3</span></a> Total removal of the tumor was curative. After surgery, patient is clinically asymptomatic after 15 months follow-up.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "multimedia" => array:2 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1491 "Ancho" => 3253 "Tamanyo" => 331021 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">(a) Whole body bone scintigraphy revealing an hypermetabolic focus in the right temporal region. (b, c) Planar lateral view and SPECT images of the skull revealed central photopenic area surrounded by rim of increased uptake. (d) Axial FLAIR-sequence MRI, images suggestive of an intradiploic epidermoid cyst of the temporal bone. (e) SPECT/MRI hybrid images.</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 2455 "Ancho" => 1625 "Tamanyo" => 792451 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Histological sections (hematoxiline and eosine staining, magnification 10× in top panel, 40× in bottom panel) showing pale-staining foamy cells with extensive foci of hemorrhage that leads to establish the diagnosis.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:3 [ 0 => array:3 [ "identificador" => "bib0020" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Xanthoma of bone" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "F. Bertoni" 1 => "K.K. Unni" 2 => "R.A. McLeod" 3 => "F.H. Sim" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Clin Pathol" "fecha" => "1988" "volumen" => "90" "paginaInicial" => "377" "paginaFinal" => "384" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3140652" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0025" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bilateral temporal bone xanthoma. Case report" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "K.A. Muthusamy" 1 => "K. Azmi" 2 => "P. Narayanan" 3 => "R. Rajagopalan" 4 => "N.A. Rahman" 5 => "V. Waran" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.3171/JNS/2008/108/2/0361" "Revista" => array:6 [ "tituloSerie" => "J Neurosurg" "fecha" => "2008" "volumen" => "108" "paginaInicial" => "361" "paginaFinal" => "364" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18240935" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0030" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Xanthoma of bone: a report of three cases and review of the literature" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "K.J. Alden" 1 => "E.F. McCarthy" 2 => "K.L. Weber" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Iowa Orthop J" "fecha" => "2008" "volumen" => "28" "paginaInicial" => "58" "paginaFinal" => "64" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19223950" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S001502820700831X" "estado" => "S300" "issn" => "00150282" ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/22538089/0000003400000005/v1_201508130058/S2253808915000865/v1_201508130058/en/main.assets" "Apartado" => array:4 [ "identificador" => "7927" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Interesting images" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/22538089/0000003400000005/v1_201508130058/S2253808915000865/v1_201508130058/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2253808915000865?idApp=UINPBA00004N" ]
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