Special collaboration
XXXV SEMNIM Congress. Highlights
XXXV Congreso de la SEMNIM. Conferencia Resumen
A. Serena Puig
Servicio de Medicina Nuclear, Hospital do Meixoeiro (EOXI-VIGO), Vigo, Pontevedra, Spain
Read
94
Timeswas read the article
30
Total PDF
64
Total HTML
Share statistics
array:23 [ "pii" => "S2253808915000944" "issn" => "22538089" "doi" => "10.1016/j.remnie.2015.09.003" "estado" => "S300" "fechaPublicacion" => "2015-11-01" "aid" => "721" "copyright" => "Elsevier España, S.L.U. and SEMNIM" "copyrightAnyo" => "2015" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Rev Esp Med Nucl Imagen Mol. 2015;34:400-11" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 88 "formatos" => array:2 [ "HTML" => 60 "PDF" => 28 ] ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S2253654X1500092X" "issn" => "2253654X" "doi" => "10.1016/j.remn.2015.07.006" "estado" => "S300" "fechaPublicacion" => "2015-11-01" "aid" => "721" "copyright" => "Elsevier España, S.L.U. and SEMNIM" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Rev Esp Med Nucl Imagen Mol. 2015;34:400-11" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1142 "formatos" => array:3 [ "EPUB" => 9 "HTML" => 864 "PDF" => 269 ] ] "es" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Colaboración especial</span>" "titulo" => "XXXV Congreso de la SEMNIM. Conferencia Resumen" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "400" "paginaFinal" => "411" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "<span class="elsevierStyleSmallCaps">XXXV</span> Congress of the SEMNIM. Highlights" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0035" "etiqueta" => "Figura 7" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr7.jpeg" "Alto" => 2351 "Ancho" => 3251 "Tamanyo" => 633393 ] ] "descripcion" => array:1 [ "es" => "<p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">PET-FDG y amiloide (florbetapir) en afasia progresiva primaria logopénica. El número de casos amiloide-positivo es alto, lo que confirma su relación con la enfermedad de Alzheimer. Estos sujetos amiloide positivos presentan un fenotipo metabólico (FDG) temporoparietal. El grupo amiloide negativo presenta un hipometabolismo más extenso, que se extiende a la región temporal anterior y frontal basal y podría corresponder a una degeneración frontotemporal (de Cabrera et al.; H Clínico San Carlos).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "A. Serena Puig" "autores" => array:1 [ 0 => array:2 [ "nombre" => "A." "apellidos" => "Serena Puig" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S2253808915000944" "doi" => "10.1016/j.remnie.2015.09.003" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2253808915000944?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2253654X1500092X?idApp=UINPBA00004N" "url" => "/2253654X/0000003400000006/v1_201510300043/S2253654X1500092X/v1_201510300043/es/main.assets" ] ] "itemAnterior" => array:19 [ "pii" => "S2253808915000932" "issn" => "22538089" "doi" => "10.1016/j.remnie.2015.09.002" "estado" => "S300" "fechaPublicacion" => "2015-11-01" "aid" => "695" "copyright" => "Elsevier España, S.L.U. and SEMNIM" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Rev Esp Med Nucl Imagen Mol. 2015;34:398-9" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 42 "formatos" => array:2 [ "HTML" => 25 "PDF" => 17 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Interesting image</span>" "titulo" => "Diagnosis of recurrent glioma and antiangiogenic treatment response by <span class="elsevierStyleSup">11</span>C-Methionine PET" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "398" "paginaFinal" => "399" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Diagnóstico de recurrencia de un glioma y respuesta al tratamiento antiangiogénico mediante PET con <span class="elsevierStyleSup">11</span>C-metionina" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 2375 "Ancho" => 3250 "Tamanyo" => 518779 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">(A) Imaging study after Stupp treatment: T1-weighted and Flair sequences MR imaging. PET/MR imaging fusion by means of software (SPM8). PET imaging with <span class="elsevierStyleSup">11</span>C-Methionine. MR shows a rounded lesion located at the genu of corpus callosum measuring 22<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>18, with adjacent bilateral frontal angiogenic edema, consistent with local recurrence. PET with <span class="elsevierStyleSup">11</span>C-Methionine shows hypermetabolic lesion (SUV target/background ratio is 5.6/1.6), thus confirming tumor recurrence. Quantification was achieved through relationship between uptake avidity of the lesion (SUV maximum) and background of gray substance of the healthy contralateral lobe (SUV mean). (B) Imaging study after Bevacizumab treatment: T1-weighted and Flair sequences MR imaging. PET/MR imaging fusion by means of software (SPM8). PET imaging with <span class="elsevierStyleSup">11</span>C-Methionine. MR shows an increase of size at the lesion located at the genu of corpus callosum (27<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>24), with similar perilesional edema spread. The PET study with <span class="elsevierStyleSup">11</span>C-Methionine shows normalization of previous metabolic activity in lesion, thus confirming response to antiangiogenic treatment, and therapy was carried on with no further suspicious signs of recurrence in our patient.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "J.R. García, M. Baquero, P. Bassa, M. Soler, M. Moragas, E. Riera" "autores" => array:6 [ 0 => array:2 [ "nombre" => "J.R." "apellidos" => "García" ] 1 => array:2 [ "nombre" => "M." "apellidos" => "Baquero" ] 2 => array:2 [ "nombre" => "P." "apellidos" => "Bassa" ] 3 => array:2 [ "nombre" => "M." "apellidos" => "Soler" ] 4 => array:2 [ "nombre" => "M." "apellidos" => "Moragas" ] 5 => array:2 [ "nombre" => "E." "apellidos" => "Riera" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S2253654X15000530" "doi" => "10.1016/j.remn.2015.04.001" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2253654X15000530?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2253808915000932?idApp=UINPBA00004N" "url" => "/22538089/0000003400000006/v1_201510310036/S2253808915000932/v1_201510310036/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Special collaboration</span>" "titulo" => "XXXV SEMNIM Congress. Highlights" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "400" "paginaFinal" => "411" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "A. Serena Puig" "autores" => array:1 [ 0 => array:3 [ "nombre" => "A." "apellidos" => "Serena Puig" "email" => array:2 [ 0 => "andres.serena.puig@sergas.es" 1 => "aserena58@hotmail.com" ] ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Servicio de Medicina Nuclear, Hospital do Meixoeiro (EOXI-VIGO), Vigo, Pontevedra, Spain" "identificador" => "aff0005" ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "XXXV Congreso de la SEMNIM. Conferencia Resumen" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0035" "etiqueta" => "Fig. 7" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr7.jpeg" "Alto" => 2346 "Ancho" => 3252 "Tamanyo" => 620104 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">FDG-PET and amyloid (florbetapir) in progressive primary logopenic aphasia. The number of amyloid-positive cases was high, thereby confirming its relationship with Alzheimer disease. These amyloid-positive subjects present a temporoparietal metabolic phenotype (FDG). The amyloid-negative group showed more extensive hypometabolism extending to the anterior temporal and frontal basal region and may correspond to frontotemporal degeneration (by Cabrera et al.; H. Clínico San Carlos).</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">The 35th Spanish Society of Nuclear Medicine and Molecular Imaging (SEMNIM) Congress was held in Burgos on June 17–19. Drs. Juan José Duque, the President of the local Organizing Committee and Enrique Prats, the President of the Executive Committee of the SEMNIM must first be congratulated for the success of this event and its social repercussion, and Dr. Angel Soriano, the President of the Scientific Committee, and all the participants should be praised for the high level of all the presentations which are undoubtedly a true reflection of the status of our specialty. On behalf of the SEMNIM, I would also like to thank the city of Burgos for its hospitality to the congress attendees. Likewise, I am grateful for being given the opportunity to make the congress highlights, which I hope will not be disappointing.</p><p id="par0010" class="elsevierStylePara elsevierViewall">It has not been the first time that our congress has been held in Burgos. Indeed the 20th congress took place here 17 years ago. Many changes have occurred in nuclear medicine (NM) and the city since then, although the essence has been preserved, albeit renewed, along with its history and art, gastronomy and the ethos of its people. This time the congress venue was the Forum Evolución. This magnificent installation hosts both artistic and scientific events such as the present involving the study and diffusion of human prehistory.</p><p id="par0015" class="elsevierStylePara elsevierViewall">The speakers and presentations took place on 2 dense days which were preceded by the pre-congress courses of the SEMNIM working groups. Six plenary and one institutional session were held in addition to the presentations. In relation to statistics, a total of 324 abstracts were received, 269 of which corresponded to nuclear physicians. Twenty-eight abstracts were excluded; 161 oral presentations were given in 18 sessions, and 135 were presented as posters in three triple sessions simultaneous to the lectures of nuclear physicians and one involving DUE/technicians. The number of presentations in the present congress was somewhat lower than that of the previous meeting but was similar to the congress held in Murcia in 2013, albeit including a larger proportion of oral presentations. For the first time the proportion of oral communications on PET versus conventional imaging was larger than that of classical NM, which is very representative of the transformation of our activity. With regard to the distribution by subject matter, among physicians, PET oncology was of note, followed by radioguided surgery. The increasingly limited presence of some classical sections of conventional NM with scarce novelties is worthy of mention, and all the oral presentations on infection-inflammation involved PET-FDG. Similar to previous congresses, the geographical origin of the attendants was largely Madrid, Andalucia and Catalunya, in that order, while nurse/technicians were more frequently from the autonomous community of Andalucia.</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Plenary sessions</span><p id="par0020" class="elsevierStylePara elsevierViewall">The first plenary session was held in the morning of Thursday the 18th and was on “The practice of nuclear cardiology”. Dr. Mut emphasized the need to verify the quality of all the stages of multidisciplinary practice in order to prepare a relevant, reliable final report. He insisted on the concept of “quality awareness” and the need for communication between the nuclear and the referring physician. Dr. Jimenez Hefferman reviewed all the aspects of equipment, personnel, SPECT/CT performance, supply, protocolization, appropriate indications and the methods of dose reduction for the development of a unit. Dr. Aguadé thoroughly reviewed the patterns of interpretation of the different aspects evaluated by nuclear cardiology: perfusion, innervation, metabolism, protocols, criteria of visual assessment, definition of risk threshold and the significance of patterns of discordance. He stressed the differences in the criteria of evaluation among perfusion studies performed for diagnostic (maximum specificity) and prognostic purposes in which sensitivity is more important. Lastly, Dr. Sanchez described the niches of perfusion studies in health care and the potential of the latest techniques available, such as resynchronization therapies and evaluation of microvascular involvement including examples of the “cuff test” and “cold test” for the detection of endothelial dysfunction.</p><p id="par0025" class="elsevierStylePara elsevierViewall">In the second morning session the “Role of PET-CT in unknown primary tumors and in paraneoplastic syndromes” was discussed. Dr. Grau described the definition and pathogenesis of paraneoplastic neurological syndromes (PNS) and the role of onconeural antibodies. He clarified the differences between definitive and possible PNS and indicated the role of cerebral PET in cerebellous degeneration and limbic encephalitis and that of whole body PET in the search for the primary tumor within the diagnostic algorithm. Dr. César Rodriguez described the challenge which tumors of unknown origin represent for medical oncologists and the diagnostic and therapeutic approaches in the genomic era. He also reported the role of immunohistochemistry in the diagnostic algorithm as well as that of molecular typing in the future, the relevance of PET-CT in cervical metastases of squamous carcinoma or in subjects with renal insufficiency or iodine allergy and their role in the follow-up of these patients, diagnostic strategies and the identification of treatment based on subtypes. Along this line, Dr. Crespo de la Jara described the important role of NM in the diagnosis of endocrinological paraneoplastic syndromes and the tracers currently available (somatostatin receptors SPECT/PET FDOPA, etc.) as well as the need for new radiotracers (RT) and the change from imaging to a theranostic approach.</p><p id="par0030" class="elsevierStylePara elsevierViewall">In the last plenary session on this day there was a debate on “Tracers of tumor hypoxia and PET”. Dr. Mulero from the National Center of Oncological Investigations (CNIO) stated that PET imaging should go beyond a role which is limited to detection and oncological diagnosis to one of biological characterization of tumors. She discussed the important role of “tumoral microenvironment” and the relevance of hypoxia imaging in the monitoring of new individualized oncological therapies. Likewise, Dr. Caballero explained the role of hypoxia in tumor aggressiveness and radioresistance as well as the strategies and techniques against the hypoxia [fractionation, intensity modulated radiotherapy (IMRT)] and the promising role of the different PET RT for noninvasive detection of hypoxia and tumor characterization, facilitating the “dose painting” strategy. Both speakers agreed on directing imaging towards “theranostic” in the search for personalized therapy. Dr. Chiti gave an in depth description of the main PET RT currently available (<span class="elsevierStyleSup">18</span>F-MISO; <span class="elsevierStyleSup">18</span>F-AZA, <span class="elsevierStyleSup">64</span>Cu-ATSM), in addition to other magnetic resonance (MR) techniques and their characteristics and limitations. He listed their differences and noted that “the best remains to be identified”. In the context of the detection of hypoxia he emphasized that some biological aspects must still be clarified, mainly related to reproducibility, due to its changing nature. He considered that PET imaging of hypoxia is promising, albeit with an as yet undefined utility.</p><p id="par0035" class="elsevierStylePara elsevierViewall">The plenary session at the beginning of the second day of the congress dealt with “The new oncological treatments. Cytostatic therapy in solid tumors”. In this session Dr. Puente described the view of medical oncologists, discussing how the evolution of antineoplastic treatments from nonselective to molecular cytotoxic agents has led to a change from homogeneous to individualized therapies based on the study of molecular mutations. This advance, however, carries difficulties in the evaluation of response to these agents. Dr. Gerbaudo explained that the criteria for the evaluation of response to cytotoxic treatments are clear: change in volume and uptake. In cytostatic therapies, the ineffectiveness of the morphological criteria (RECIST, etc.) produces certain questions as to what percentage of change in the SUV, from basal PET to the intermediate and interim stage, is significant and an indicator of effectiveness. Not only the magnitude which is probably different in different tumors, but also the speed of the change is important, and thus, several areas and aspects remain unclear and must be solved. From what we have learned to date, it can be said that a 20–25% reduction in the SUV during the interim evaluation study (after the 2nd cycle) indicates good response and the greater and earlier the reduction the better the response.</p><p id="par0040" class="elsevierStylePara elsevierViewall">In the session on “Radiolocalization of lesions and the sentinel lymph node in oral cancer surgery”, Dr. Rioja summarized her experience in the radiolocalization of lesions with radioactive seeds of which she is an expert. She described the advantages in the reliability of this technique, the selection of the access route, better focused on the lesion and lower resected volume, among others. In relation to oral cancer, Dr. Martí-Pagés made an in depth description of the resection and reconstruction techniques and the highly developed role of lymph node dissection from radical to functional. In his opinion, selective sentinel lymph node biopsy (SSLNB) is the technique of choice for lymph node staging in early onset of oral cancer. He reviewed the methodology of the isotopic method indicating the importance of lymphoscintigraphic imaging of tumor drainage for surgeons (and patient survival) as a guide to locate the sentinel lymph node (SLN) in these complex areas with variable drainage routes. In his presentation, Dr. Valdés-Olmos stressed the role of nuclear techniques in this context, with a masterful description of the protocols of exploration for the SLN in head and neck cancer, the contribution of SPECT-CT in 3D imaging and the complementary role of lymphoscintigraphy and fusion CT to design a roadmap for the surgeon. He discussed the hybrid tracer technique (radioactive-fluorescent) and its importance in the detection of lymph nodes close to the tumor. He finished his presentation with a description of the new technologies such as those of hybrid mixed/virtual augmented reality environment and their great potential.</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Presentations</span><p id="par0045" class="elsevierStylePara elsevierViewall">Now I will discuss the presentations of greatest interest by subject, the selection of which was based on the qualification criteria of the Scientific Committee. The number of these presentations was conditioned by the size of the conference and thus, others of similar relevance would also deserve to be mentioned.</p><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">FDG-PET: lymphoma, breast, lung</span><p id="par0050" class="elsevierStylePara elsevierViewall">The first is on FDG-PET in the most prevalent tumors (lymphoma, breast, lung). In Hodgkin's lymphoma the Department of Nuclear Medicine of the Son Espases University Hospital retrospectively analyzed the performance of the new criteria of interpretation of the 2014 Consensus of Lugano versus the previous criteria of the Consensus of the Harmonization Project in the final evaluation of response to induction therapy (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>). After a mean follow-up of 22 months and with a survival rate of 100% and 81% of patients being disease-free, reinterpretation of initial response according to the new Lugano criteria showed a significant increase in the specificity and the positive predictive value. This could save the need for confirmatory biopsies, follow-up tests or overtreatment. In a staging study of follicular lymphoma Dr. Jimenez Londoño et al. of the University Hospital of Ciudad Real analyzed the relationship between the clinical variables (histological grade, FLIPI risk and tumor load) and the metabolic variables expressed by a “PET score” combining different items (SUVmax, size and number of lesions, bone marrow and extra lymph node involvement). The FLIPI risk and tumor load showed a significant relationship with the SUVmax and the PET score. The tumoral grade was not related to the metabolic variables. This group concluded that initial FDG-PET is an indicator of biological aggressiveness and prognosis in follicular lymphoma. From the same center, Dr. Garcia Vicente et al. presented the results of a multicenter study including 144 women with locally advanced breast cancer undergoing neoadjuvant chemotherapy (CHT) (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>). PET was performed in two phases assessing the SUVmax of the tumor and the retention index correlated with the grade of response and the molecular subtype. They found significantly higher initial SUV values in responder patients and particularly in the subgroups of patients with a high-risk phenotype (HER2+ and triple negative). In lung cancer, the team from the Clínica Universidad de Navarra evaluated the relationship between FDG uptake and the expression of the different molecular profiles in nonsmall cell lung cancer. In a group of 127 patients they found a significantly higher SUVmax in subjects with ALK rearrangement or a mutation of the KRAS than in EGFR-positive patients or those without any genetic alteration, suggesting a more aggressive behavior in these two subgroups. Nonetheless, the overlapping of values did not allow the prediction of a molecular profile based on the SUVmax.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">FDG-PET: other tumors</span><p id="par0055" class="elsevierStylePara elsevierViewall">In other tumors evaluated with FDG-PET the study by Dr. Ortega and her group in the Hospital Clínico San Carlos de Madrid found a relationship between the Breslow index and the FDG PET-CT results in the initial staging of cutaneous melanoma. They observed significantly higher mean values of the Breslow index in the group with positive PET results. With a ROC curve they proposed an optimal cut off of 5<span class="elsevierStyleHsp" style=""></span>mm, providing high discrimination. Patients with a Breslow score greater than or equal to 5<span class="elsevierStyleHsp" style=""></span>mm also showed a shorter survival on follow-up. A retrospective study including 241 patients carried out at the Department of Nuclear Medicine of the Hospital Virgen de las Nieves in Granada analyzed the utility of FDG-PET in M staging in rectal cancer. These authors found metastatic disease in 20% of the cases which was not suspected in two-thirds of these patients and, additionally, secondary tumors were found in 6% of the patients. The diagnostic accuracy was close to 97% thereby supporting the utility of FDG in M staging and its value in the optimization of therapy. In turn, investigators from the Hospital Vall d’Hebron compared the results of FDG-PET and technetium octreotide in patients with neuroendocrine tumors and found a greater overall sensitivity and a higher number of primary localizations with FDG-PET. Despite a greater number of G1 positive patients with <span class="elsevierStyleSup">99m</span>Tc-tektrotyd, and G2, G3 with FDG, combined study allows the characterization of a high proportion of mixed or unexpected patterns which could modify and condition individualized therapy.</p><p id="par0060" class="elsevierStylePara elsevierViewall">Of note were two presentations which underline the interest of FDG-PET in IMRT planning. In a study by the Hospital 12 de Octubre involving head and neck tumors (<a class="elsevierStyleCrossRef" href="#fig0015">Fig. 3</a>), FDG-PET was found to modify tumor extension in 27% of the patients and lymph node staging in 42%, with the consequent changes in the respective GTV. Likewise, intention to treat was modified to palliative therapy in 6% of the patients due to the detection of metastasis. On the other hand, a group from the Hospital Vall d’Hebron compared the volumes to be irradiated calculated by “slow CT scan” and “PET-CT 4D gating” in 26 patients with bronchogenic carcinoma who were candidates for radical IMRT. Although no differences were observed in the mean volumes calculated with both techniques, they did find a high percentage of important differences greater than 5<span class="elsevierStyleHsp" style=""></span>ml at an individual level. In 40% of the cases the differences in the co-registry of volumes was greater than cm at some axes.</p><elsevierMultimedia ident="fig0015"></elsevierMultimedia></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">PET: other radiotracers</span><p id="par0065" class="elsevierStylePara elsevierViewall">In a study on PET with RT other than FDG in urological and brain neoplasms Dr. Lorenzo-Bosquet et al. analyzed the relationship between the uptake of <span class="elsevierStyleSup">11</span>C-methionine and the pathological grade and survival in primary and metastatic brain tumors. Using the tumor/cortex index they found significant differences between high- and low-grade primary tumors but not between high grade tumors and metastasis, on one hand, and low-grade tumors and metastasis, on the other hand. The grade of uptake was correlated with Ki67 proliferation. A cut off of 1.9 defined two groups with different survival. Among the factors analyzed, age and the grade were predictors of overall survival. The groups from the IDI-Bellvitge and CETIR-ERESA in Esplugues presented a study on the sequential use of FDG-PET and PET-methionine in the differential diagnosis of recurrence versus radionecrosis in primary and metastatic brain tumors treated with IMRT. Dual-time FDG-PET was used in the evaluation (from 1 and 3<span class="elsevierStyleHsp" style=""></span>h post-injection) performing PET-methionine in negative or undetermined cases. They reported a high yield with dual-time FDG-PET which was attributed to assessment using PET-MR co-registry. PET-methionine detected two negative cases in the FDG which was a false negative in one confirmed case. These authors suggested that sequential use is cost-effective and accurate.</p><p id="par0070" class="elsevierStylePara elsevierViewall">The group from the Hospital General Universitario de Valencia presented their results in the detection of disease using <span class="elsevierStyleSup">18</span>F-fluorocholine in patients with biochemical relapse of prostate adenocarcinoma. They studied 63 patients with a global detection rate of 85% (8% of the prostate, 21% pelvic lymph nodes and 57% distant metastasis). Two second-time tumors were detected. The rate of positive results was related to the PSA level, but an 81% of sensitivity was achieved even in patients with PSA levels lower than 2 (median 0.9). In this same field, the PET-IDI Unit of Bellvitge described an interesting study on the rate of detection and the type of recurrence related to the initial parameters of risk. They studied 75 cases referred for biochemical relapse and obtained a global detection rate of 79%. According to a classification of exclusively prostate, locoregional or distant metastasis, a greater proportion of <span class="elsevierStyleItalic">T</span><span class="elsevierStyleHsp" style=""></span>≥<span class="elsevierStyleHsp" style=""></span>3 was observed in patients with metastasis, a Gleason score >8 or with high-risk based on the Amico classification. Seventy-five percent of PET negative patients presented an initial PSA level less than 10. They concluded that the detection of relapse with fluorocholine and the type of relapse are correlated with the initial parameters of risk. Dr. García Garzón of the CETIR-ERESA group reported the results obtained with PET <span class="elsevierStyleSup">11</span>C-choline in patients with prostate cancer with biochemical relapse (<a class="elsevierStyleCrossRef" href="#fig0020">Fig. 4</a>). The use of PET-choline in the evaluation detected 50% more negative subcentimetric lymph nodes of CT, allowing IMRT planning. In the assessment of therapeutic efficacy at one year, PET-choline allowed the classification of response with prognostic significance: 80% of partial responders presented a new relapse during follow-up compared to only 40% of later relapse in subjects with complete response. This study received the award for the best oral communication.</p><elsevierMultimedia ident="fig0020"></elsevierMultimedia></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Radioguided surgery: breast</span><p id="par0075" class="elsevierStylePara elsevierViewall">With regard to the presentations on radioguided surgery and starting with that on SSLNB in breast cancer, the team of the Hospital Universitari Joan XXIII de Tarragona described their results with the SSLNB technique in patients with N1N2 axillary involvement and complete axillary response by ultrasonography or MR following neoadjuvant CHT. They obtained a detection rate of 90.3% with an elevated rate of axillary involvement in the lymph node dissection of undetected cases. The global efficacy of the technique was 93.7% with only 6.2% of false negative results. They concluded that with the methodology applied the technique is feasible and the yield is in accordance with the established standards. With respect to the extension of indications Dr. Díaz-Exposito et al. from the Hospital Clínico de Valencia confirmed the feasibility of this technique in patients with breast cancer and a history of previous plastic breast surgery (prosthesis or breast reduction) or tumorectomy (<a class="elsevierStyleCrossRef" href="#fig0025">Fig. 5</a>). They obtained a global detection rate of 90.4%, which is somewhat lower than optimal, especially in patients submitted to tumorectomy but without an increase in the proportion of extra-axillary drainage. In three quarters of the cases the administration of colloid was periareolar.</p><elsevierMultimedia ident="fig0025"></elsevierMultimedia><p id="par0080" class="elsevierStylePara elsevierViewall">The tumoral characteristics related to margin involvement in the first surgical specimen obtained with the sentinel node and occult lesion localization (SNOLL) technique was studied by the group from Ciudad Real in 132 patients. The labeled tumor was identified in all the cases. Of all the characteristics evaluated only the presence of an intraductal component was associated with a greater probability of involvement of the initial margins. Infiltration of the initial margin was also associated with the presence of micrometastasis in the SLN. The team from the Hospital Dr. Peset in Valencia compared the efficacy of the portable gamma camera versus mammography in the verification of sufficient margins in the surgical piece obtained by radioguided occult lesion localization (ROLL). Although the differences were not statistically significant, the portable gamma camera avoided a greater number of reinterventions. The authors recommended the combined use of the two techniques. Two teams, one from the Hospital Clinic de Barcelona and the other from Meixoeiro de Vigo evaluated the efficacy of the SLN detection using ferromagnetic particles in breast cancer. The global detection rate was slightly superior with the conventional technique, although the Sentimag™ detected a slightly higher number of lymph nodes. The impossibility to perform previous imaging and planning makes it difficult to extend the use of this technique to other tumors with complex lymphatic drainage.</p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Radioguided surgery: other tumors</span><p id="par0085" class="elsevierStylePara elsevierViewall">With respect to radioguided surgery in other tumors the results of the questionnaire by the Radioguided Surgery Group of the Society on the application of SLN in melanoma were presented. Forty-two centers responded. Radioguided surgery was generally accepted as a highly accurate method of lymph node staging in melanoma. Standardization of the basic technique is high with differences being linked to the equipment used (availability of portable gamma camera); SPECT-CT is mainly used but only in selected cases.</p><p id="par0090" class="elsevierStylePara elsevierViewall">Although SSLNB is mainly used in breast cancer and, to a lesser degree, in melanoma, its use is increasing in different urological and gynecological diseases as shown in the presentations. Thus, the group of the Hospital La Fe of Valencia validated the SSLNB technique in intermediate-high/high prostate adenocarcinoma in a group of 23 patients (<a class="elsevierStyleCrossRef" href="#fig0030">Fig. 6</a>). The technique includes radioguided intraprostatic injection, verification by portable gamma camera, SPECT-CT at 2<span class="elsevierStyleHsp" style=""></span>h and resection control with an intraoperative gamma camera. Migration was observed in all the cases with infiltration of the SLN in 23% and a negative predictive value (NPV) of 100% compared to the results of lymph node dissection. The high proportion of para-aortic and presacral migrations detected by scintigraphy was of note and may determine extended lymph node dissections.</p><elsevierMultimedia ident="fig0030"></elsevierMultimedia></span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Neurosciencies</span><p id="par0095" class="elsevierStylePara elsevierViewall">In the chapter on neurosciences, a group of investigators from the Universidad de Málaga studied brain metabolism using PET-FDG in persons with chronic post-ictal aphasia and the modifications related to therapy with donepezil, also applying structural and functional MR. They concluded that donepezil increases the efficiency of the neural network involved in visual attention and nomination, and that imaging with FDG allows early detection of potential responders to this therapy. Drs. Cabrera and Matías-Guiu et al. from the Hospital Clínico San Carlos of Madrid, presented the results of the combined study with FDG and florbetapir, favoring the presence of two subtypes in progressive primary logopenic aphasia (<a class="elsevierStyleCrossRef" href="#fig0035">Fig. 7</a>). The frequency of amyloid-positive patients observed (69%) confirms the frequent association of this entity with Alzheimer disease; this subtype presents left temporal-parietal hypometabolism. A second, amyloid-negative group, presented more extensive hypometabolism which also extended to the anterior temporal and basal frontal regions and may correspond to frontotemporal degeneration. These findings underline the interest of amyloid imaging in logopenic aphasia. The team of the Clínica Universidad of Navarra evaluated the reproducibility of amyloid image reading in different equipment (<a class="elsevierStyleCrossRef" href="#fig0040">Fig. 8</a>). They performed a qualitative and quantitative comparison of the findings in 2 PET-CT equipments; one conventional and the other being last generation PET-CT with PSF and TOF using phantoms and a clinical group. They found good concordance between equipment in the visual analysis (kappa 0.83), although the last generation equipment reduced the number of doubtful cases. The SUVR was systematically greater in the conventional equipment. The white matter/cerebellous ratios were lower with the post-injection time. These findings are important for the standardization of studies.</p><elsevierMultimedia ident="fig0035"></elsevierMultimedia><elsevierMultimedia ident="fig0040"></elsevierMultimedia></span><span id="sec0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Cardiovascular</span><p id="par0100" class="elsevierStylePara elsevierViewall">Among the presentations on the subject of cardiovascular disease that by the group from the Hospital Universitario de Salamanca was of note. They studied the relationship between ventricular dyssynchrony during effort assessed by an increase in the histogram bandwidth or an increase in the deviation of the phase histogram on the gated-SPECT using QGS software. This group prospectively analyzed 333 patients without a recent infarction/angina, conduction disorder, valvular surgery or nonischemic dilatation. Of the patients presenting ischemia without a previous by-pass, 57% and 37% presented an increase in histogram bandwidth or a rise in the deviation of the histogram in relation to the severity of the ischemia. Dyssynchrony in patients with ischemia is more frequent than a fall in the ejection fraction or transitory dilatation of the left ventricle. These findings were also observed in patients with a previous by-pass and thus, these authors concluded that ventricular dyssynchrony estimated by gated myocardial perfusion SPECT is correlated with the presence of ischemia in heart disease patients and is also useful in subjects with previous by-pass surgery. The investigators of the Department of Nuclear Medicine of the Hospital Virgen del Rocío of Sevilla studied the prognostic value of perfusion studies in diabetic patients without significant lesions on coronary angiography. They performed a 3-year retrospective cohort study with the same follow-up period. Thirty-seven patients with these criteria were selected and the rate of events was compared with a control group of 29 nondiabetic patients with scintigraphic ischemia and normal coronary angiography. The rate of events in diabetic patients with scintigraphic ischemia (44.8%) was found to be higher than that of the nondiabetic ischemic group (24%). No events were reported in diabetic subjects with a normal scintigraphy. Similar to other authors they concluded that the detection of microvascular involvement by SPECT has an elevated prognostic value for cardiac events in diabetic patients without coronary obstruction.</p></span><span id="sec0050" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Therapy</span><p id="par0105" class="elsevierStylePara elsevierViewall">The Department of Nuclear Medicine of the Hospital Puerta de Hierro described their experience with metabolic therapy with <span class="elsevierStyleSup">177</span>Lutetium-DOTATATE in progressive metastatic neuroendocrine tumors refractory to other therapies (<a class="elsevierStyleCrossRef" href="#fig0045">Fig. 9</a>). To date, they have treated six patients who have received 1–4 cycles of 7.4<span class="elsevierStyleHsp" style=""></span>GBq (200<span class="elsevierStyleHsp" style=""></span>mCi) with an interval of 6–8 weeks. The radiotracer was administered 30<span class="elsevierStyleHsp" style=""></span>min after the start of an infusion of amino acid for renal protection. In all the patients the lesions remained stable with improvement in the general status and without immediate toxicity. The treatment is simple to administer and requires individual authorization from the Spanish Medicines Agency. The group from the Hospital Reina Sofía of Córdoba presented their experience with the combined use of <span class="elsevierStyleSup">90</span>Ytrium–Zevalin and CHT, the Z-BEAM scheme compared to CHT BEAM alone, for bone marrow autotransplantation conditioning in patients with B-cell nonHodgkin's lymphoma. They retrospectively evaluated 54 patients in two groups, one of which received the maximum dose of zevalin 7 days before the initiation of CHT. The demographic and tumoral characteristics (IPI, FLIPI and grade) were similar in both groups, but the percentage of patients in complete initial remission was lower in the Z-BEAM group. No differences were observed in myelotoxicity or transplant-related toxicity. The overall survival and the progression-free interval were related to the clinical status at transplantation. It was concluded that the patients at greatest risk who did not achieve previous complete remission might benefit from the Z-BEAM scheme for conditioning.</p><elsevierMultimedia ident="fig0045"></elsevierMultimedia><p id="par0110" class="elsevierStylePara elsevierViewall">In a classical indication for metabolic IMRT the team from H. Ramón y Cajal summarized their results in an infrequent and more complex group of patients less than 18 years of age with differentiated thyroid carcinoma. Over 33 years they recruited 36 cases out of a total of 1500 and concluded that the same rigorous protocol as that used in adults should be applied in children. With the spacing of treatment no severe adverse effects are observed, even at high cumulative doses. Patients should be followed throughout their lifetime due to the possibility of late relapse. The Nuclear Medicine Service of the Hospital Clínico of Zaragoza also described the utility of the reevaluation of risk criteria treatment of differentiated thyroid carcinoma based on initial response to treatment using the modified Tuttle criteria. They retrospectively analyzed 147 patients whose response to surgery and ablation was classified as excellent, acceptable or incomplete. Up to 56% of the subjects with initial high/intermediate risk according to the ATA criteria were restaged with excellent response. All of the patients with excellent response presented complete remission at the end of follow-up.</p></span><span id="sec0055" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0055">Infection and inflammation</span><p id="par0115" class="elsevierStylePara elsevierViewall">As mentioned beforehand all of the oral communications on infection-inflammation were on FDG-PET. Dr. Jimenez-Ballvé et al. of the Hospital Clínico San Carlos de Madrid studied the effectiveness of PET-FDG in the diagnosis of infectious valvular endocarditis. They analyzed 63 foci in 46 patients with suspicion of definitive or possible infectious endocarditis. The sensitivity, specificity and overall accuracy were 77%, 74% and 76%, respectively. In the study of valvular prostheses, the sensitivity and NPV were 100% with an accuracy of 86%. To the contrary, in endocarditis of the native valve the sensitivity and NPV were nearly 50%, with an accuracy of only 63%. They concluded that FDG-PET is useful in the diagnosis of infectious endocarditis of prosthesis but has less accuracy in native valve infection. Along a similar line, the team from the Hospital of the Vall d’Hebron led by Dr. Aguadé studied the added value of FDG-PET/CT angiography over the clinical criteria in the diagnosis of infectious endocarditis and the differences in yield between the evaluation of prosthetic valves and intracardiac devices (<a class="elsevierStyleCrossRef" href="#fig0050">Fig. 10</a>). They carried out a cohort study including 92 patients and obtained a sensitivity of 51% for the Duke clinical criteria, 87% with the FDG/CT angiography study and 90% with combined assessment. The correlation of FDG/CT angiography versus ultrasonography was low-moderate. Semiquantitative evaluation allowed the definition of cut off points of the SUVmax and SUVmax/background ratio which maximized the sensitivity or the specificity of the evaluation of the valves but not of the devices which presented scarce background contrast.</p><elsevierMultimedia ident="fig0050"></elsevierMultimedia><p id="par0120" class="elsevierStylePara elsevierViewall">The Department of Nuclear Medicine of the Hospital Marqués of Valdecilla in Santander described their results of the evaluation of aortitis in patients with rheumatic polymyalgia. The study included 40 consecutive patients with rheumatic polymyalgia and suspicion of associated aortitis assessed by FDG-PET semiquantification performed at 180<span class="elsevierStyleHsp" style=""></span>min post-injection. The lesion/background index (expressed as SUVmax vessel wall/SUVmax vascular pool) was significantly greater in patients with aortitis (1.63) compared to those without (1.22). Analysis of the ROC curves showed a maximum sensitivity for a value of 1.34 of the index with an area under the curve of 0.997.</p></span><span id="sec0060" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0060">Osteoarticular, endocrinology and others</span><p id="par0125" class="elsevierStylePara elsevierViewall">To complete the report of the most noteworthy presentations of the physicians, among those corresponding to the classical sections of conventional NM and related to the subject of the osteoarticular system, the award for the best poster was given to Dr. Camarero et al from the Complejo Hospitalario of Navarra. This group evaluated the added value of SPECT-CT in the study of disease of the foot. After evaluating 54 patients they concluded that three-phase multiplanar scintigraphy is sufficient in the disease of the forefoot, plantar fascitis and Achilles tendon enthesopathy. Emission tomography provides an appropriate anatomical localization of known lesions and may, sometimes, detect different unexpected pathologies. Lastly, SPECT-CT accurately identifies affected bones or joints, being of greatest interest in the study of the tarsus and post-surgical assessment (<a class="elsevierStyleCrossRef" href="#fig0055">Fig. 11</a>).</p><elsevierMultimedia ident="fig0055"></elsevierMultimedia><p id="par0130" class="elsevierStylePara elsevierViewall">Among the studies on endocrinology the team from the Department of Nuclear Medicine of the Hospital Santa Lucia of Cartagena compared intraoperative PTH determination with verification of correct minimally invasive excision of parathyroid adenoma in the operating room with a portable gamma camera. Both methods were found to be equally effective, and thus, radioguided surgery could rule out biochemical determination thereby shortening surgical time. Within the field of gastroenterology, the Servicio CETIR-ERESA of Terrasa has revitalized the use of the value of <span class="elsevierStyleSup">75</span>SeHCAT in the evaluation of patients with chronic watery diarrhea. Patients with cholecystectomy (68%) showed a higher percentage of malabsorption of biliary acids independently of the post-surgical period than those not undergoing surgery. The response to initially high cholestyramine was maintained in the long-term in 50% of the patients. Lastly, Dr. Roca Engronat from the University Hospital of Bellvitge presented new reference values for the estimation of ERPF with two-sample plasma clearance of <span class="elsevierStyleSup">99m</span>Tc-MAG3 in a group of 53 potential kidney donors. A reduction in FEPR was found with age, being significant after 50, and they provided a regression equation for the estimation of the ERPF reference range using an adequate age interval.</p><p id="par0135" class="elsevierStylePara elsevierViewall">In the section on radiotracers, the “Study of in vivo biodistribution of polymeric protein nanoparticles (PPNP) radiolabeled with <span class="elsevierStyleSup">99m</span>Tc in a orthotopic nude mice hepatocarcinoma model” presented by Dr. Ramos et al. from the Clínica Universidad of Navarra obtained the maximum qualification from the Scientific Committee. In the presentation of the nurse/technicians the evaluators considered the most interesting study to be that on the “Validation of leukocyte labeling with a new exametazime kit” carried out by Rocamora Lozano et al. from the Hospital Santa Lucía of Cartagena.</p><p id="par0140" class="elsevierStylePara elsevierViewall">I would like to finish with some thoughts on the evolution of our specialty in recent years and there is no better place to do that but in this congress. As mentioned previously, the National Congress of our society was held in this city 17 years ago. On looking over the book of abstracts and press cuttings of the congress we can see the in depth transformation our specialty has undergone over this period. At that time a “revolutionary diagnostic method” was presented to society that of positron emission tomography, a technique involving three devices installed at a state level. There were only 11 preliminary clinical presentations on PET, and these were obviously exclusively with <span class="elsevierStyleSup">18</span>F-FDG. The possibilities of registry and fusion imaging and their distant delivery and “remote diagnosis” were also discussed. The main subjects covered were thallium/tetrofosmin in oncology, breast scintigraphy with thallium, immunoscintigraphy, labeled leucocytes, RIA… only a few presentations (2) spoke about SLN in melanoma. The contrast with the present state of NM discussed above is clear: the qualitative and quantitative leap is astronomical. In addition to the classical techniques today we have strong, widespread and consolidated multimodal studies (PET-CT), with access to different RT. We have radioguided surgery to localize lesions and SLN in very different places of the body and, in addition, our scientific production has multiplied and generalized in origin. There will also be “aspects to be solved”, challenges to confront and beat in the present and the future. This will all be seen and revealed in future congresses. With that in mind, our next meeting will be placed in Barcelona in 2016!</p></span></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:2 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Plenary sessions" ] 1 => array:3 [ "identificador" => "sec0010" "titulo" => "Presentations" "secciones" => array:10 [ 0 => array:2 [ "identificador" => "sec0015" "titulo" => "FDG-PET: lymphoma, breast, lung" ] 1 => array:2 [ "identificador" => "sec0020" "titulo" => "FDG-PET: other tumors" ] 2 => array:2 [ "identificador" => "sec0025" "titulo" => "PET: other radiotracers" ] 3 => array:2 [ "identificador" => "sec0030" "titulo" => "Radioguided surgery: breast" ] 4 => array:2 [ "identificador" => "sec0035" "titulo" => "Radioguided surgery: other tumors" ] 5 => array:2 [ "identificador" => "sec0040" "titulo" => "Neurosciencies" ] 6 => array:2 [ "identificador" => "sec0045" "titulo" => "Cardiovascular" ] 7 => array:2 [ "identificador" => "sec0050" "titulo" => "Therapy" ] 8 => array:2 [ "identificador" => "sec0055" "titulo" => "Infection and inflammation" ] 9 => array:2 [ "identificador" => "sec0060" "titulo" => "Osteoarticular, endocrinology and others" ] ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Serena Puig A. XXXV Congreso de la SEMNIM. Conferencia Resumen. Rev Esp Med Nucl Imagen Mol. 2015. <span class="elsevierStyleInterRef" id="intr0005" href="doi:10.1016/j.remn.2015.07.006">http://dx.doi.org/10.1016/j.remn.2015.07.006</span></p>" ] ] "multimedia" => array:11 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 2438 "Ancho" => 3251 "Tamanyo" => 883096 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Hodgkin's lymphoma. The evaluation of response to inductive treatment with the new Lugano criteria (2014) significantly raises the positive predictive value and the specificity of FDG-PET compared to the Consensus Criteria of the Harmonization Project of 2007. The classification of response with these criteria better discriminates the progression-free interval (by Daumal et al.; Son Espases University Hospital).</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 2333 "Ancho" => 3260 "Tamanyo" => 682655 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Breast cancer. FDG-PET in the prediction of response to neoadjuvant chemotherapy. Higher initial SUV values were found in the group of responders, particularly in those with the high-risk phenotye (HER2+ and triple negative) (by García Vicente et al.; Ciudad Real University Hospital).</p>" ] ] 2 => array:7 [ "identificador" => "fig0015" "etiqueta" => "Fig. 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 2416 "Ancho" => 3251 "Tamanyo" => 1008446 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">FDG-PET in radiotherapy planning of head and neck tumors. PET modifies the tumor-GTV in 27% and lymph node-GTV in 42%. Metastasis was detected in 6%, modifying the intention-to-treat to palliative therapy (by Pedraza et al.; 12 de Octubre University Hospital).</p>" ] ] 3 => array:7 [ "identificador" => "fig0020" "etiqueta" => "Fig. 4" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr4.jpeg" "Alto" => 2438 "Ancho" => 3241 "Tamanyo" => 634117 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleSup">11</span>C-Choline PET in the selection and planning of salvage radiotherapy in prostate cancer. Negative lymph nodes were detected in 50% on CT (subcentimetric), being the only N involvement in half. The type of response to radiotherapy (partial or complete) determines the probability and mean of relapse (by García et al.; CETIR-ERESA Esplugues).</p>" ] ] 4 => array:7 [ "identificador" => "fig0025" "etiqueta" => "Fig. 5" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr5.jpeg" "Alto" => 2251 "Ancho" => 3001 "Tamanyo" => 700418 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Selective sentinel lymph node biopsy in breast cancer in patients with a history of previous breast surgery. The global detection rate is satisfactory (90.4%), with no increase in extra-axillary drainage, albeit being lower than desired in patients with a history of tumorectomy (by Díaz-Expósito et al.; H. Clínico U of Valencia).</p>" ] ] 5 => array:7 [ "identificador" => "fig0030" "etiqueta" => "Fig. 6" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr6.jpeg" "Alto" => 1835 "Ancho" => 2490 "Tamanyo" => 476295 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">SSLNB in intermediate/high risk prostate cancer. The technique was validated in the University Hospital La Fe obtaining a NPV of 100%. The significant number of atypical drainages conditioning extended lymph node dissection in the case of a positive SLN was of note.</p>" ] ] 6 => array:7 [ "identificador" => "fig0035" "etiqueta" => "Fig. 7" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr7.jpeg" "Alto" => 2346 "Ancho" => 3252 "Tamanyo" => 620104 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">FDG-PET and amyloid (florbetapir) in progressive primary logopenic aphasia. The number of amyloid-positive cases was high, thereby confirming its relationship with Alzheimer disease. These amyloid-positive subjects present a temporoparietal metabolic phenotype (FDG). The amyloid-negative group showed more extensive hypometabolism extending to the anterior temporal and frontal basal region and may correspond to frontotemporal degeneration (by Cabrera et al.; H. Clínico San Carlos).</p>" ] ] 7 => array:7 [ "identificador" => "fig0040" "etiqueta" => "Fig. 8" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr8.jpeg" "Alto" => 2300 "Ancho" => 3251 "Tamanyo" => 688416 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Evaluation of the accumulation of amyloid in the brain by different equipments. Good concordance is seen in the visual analysis (kappa 0.83), although the new generation scanner reduces the number of doubtful cases. The SUVR is systematically greater in the conventional equipment. The white matter/brain ratios fall with the post-injection time (by Sancho et al.; Clínica Universidad de Navarra).</p>" ] ] 8 => array:7 [ "identificador" => "fig0045" "etiqueta" => "Fig. 9" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr9.jpeg" "Alto" => 2511 "Ancho" => 3251 "Tamanyo" => 728604 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Treatment with <span class="elsevierStyleSup">177</span>Lu-DOTA TATE in metastatic neuroendocrine tumors is simple, acceptable and safe, stabilizing the disease and improving the quality of life (by Plaza de las Heras et al. Puerta de Hierro University Hospital).</p>" ] ] 9 => array:7 [ "identificador" => "fig0050" "etiqueta" => "Fig. 10" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr10.jpeg" "Alto" => 2438 "Ancho" => 3252 "Tamanyo" => 867944 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">PET-FDG/CT angiography provides added diagnostic value to the Duke clinical criteria in infectious endocarditis in both prosthetic valves and intracardial devices. The semiquantitative criteria (SUV) are only valid for the valves (by Aguadé et al.; Vall d’Hebron University Hospital).</p>" ] ] 10 => array:7 [ "identificador" => "fig0055" "etiqueta" => "Fig. 11" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr11.jpeg" "Alto" => 2438 "Ancho" => 3251 "Tamanyo" => 506271 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Added value of SPECT-CT in foot disease. This technique accurately identifies the bones and joints affected, being of greatest interest in the study of the tarsus and post-surgical assessment (by Camarero et al.; Complejo Hospitalario of Navarra).</p>" ] ] ] ] "idiomaDefecto" => "en" "url" => "/22538089/0000003400000006/v1_201510310036/S2253808915000944/v1_201510310036/en/main.assets" "Apartado" => array:4 [ "identificador" => "7982" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Special collaboration" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/22538089/0000003400000006/v1_201510310036/S2253808915000944/v1_201510310036/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2253808915000944?idApp=UINPBA00004N" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 April | 2 | 1 | 3 |
| 2023 June | 2 | 1 | 3 |
| 2019 February | 30 | 0 | 30 |
| 2018 June | 0 | 1 | 1 |
| 2018 May | 0 | 3 | 3 |
| 2018 April | 0 | 7 | 7 |
| 2018 February | 6 | 2 | 8 |
| 2018 January | 2 | 0 | 2 |
| 2017 December | 12 | 0 | 12 |
| 2017 November | 7 | 1 | 8 |
| 2017 February | 0 | 1 | 1 |
| 2016 December | 0 | 1 | 1 |
| 2016 November | 0 | 1 | 1 |
| 2016 October | 0 | 2 | 2 |
| 2016 September | 0 | 2 | 2 |
| 2016 July | 0 | 1 | 1 |
| 2016 May | 0 | 1 | 1 |
| 2016 February | 2 | 2 | 4 |
| 2015 December | 1 | 0 | 1 |
| 2015 November | 0 | 3 | 3 |
Show all
