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Inicio Revista Española de Medicina Nuclear e Imagen Molecular (English Edition) Primary epithelioid trophoblastic tumor with a synchronous breast carcinoma dete...
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Vol. 30. Issue 6.
Pages 368-371 (November 2011)
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Vol. 30. Issue 6.
Pages 368-371 (November 2011)
Primary epithelioid trophoblastic tumor with a synchronous breast carcinoma detected only with FDG-PET/CT Scan
Tumor primario trofoblástico epitelioide y carcinoma sincrónico de mama detectado sólo con FDG-PET/CT
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T.. Karaa,
Corresponding author
taylankara@gmail.com

Corresponding author. taylankara@gmail.com
, P.. Ozcan Karab, F.. Babac, C.. Celikd, G.. Kara Gedikb
a Department of Radiology, Beyhekim Hospital, Selcuklu, Konya, Turkey
b Department of Nuclear Medicine, Selcuklu Medical Faculty, Selcuklu, Konya, Turkey
c Department of Pathology, Selcuklu Medical Faculty, Selcuklu, Konya, Turkey
d Department of Obstetrics and Gynecology, Selcuklu Medical Faculty, Selcuklu, Konya, Turkey
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Epithelioid trophoblastic tumor is a recently described, rare and distinctive type of gestational trophoblastic tumor. We report the case of a 31-year old patient who had a full-term pregnancy 18 months before presentation. She had a right axillary lymph node metastasis and was referred for FDG-PET/CT scan for evaluation of distant metastasis and to detect primary malignancy. The axillary lymph node biopsy revealed metastatic breast carcinoma. FDG-PET/CT revealed increased uptake of right axillary lymph node, soft tissue density lesion with a diameter of 24 mm on left cervical region with increased FDG uptake, increased uptake on cervical region and left inguinal lymph node with increased uptake. Pelvic MRI imaging and ultrasonography were negative for malignancy in cervical region. Biopsy of the lesion was consistent with epithelioid trophoblastic tumor in cervical region. Gestational trophoblastic tumor was not suspected because she had no signs such as abnormal vaginal bleeding. FDG-PET/CT demonstrated the primary lesion in cervical region. We report a rare case of primary epithelioid trophoblastic tumor detected only with FDG-PET/CT scan which synchronized with breast carcinoma.

Keywords:
Epithelioid trophoblastic tumor
FDG-PET/CT
Axillary lymph node
Breast carcinoma

El tumor trofoblástico epitelioide es un raro tumor gestacional recientemente descrito. Una paciente de 31 años, que tuvo un embarazo a término hace 18 meses, presentó una adenopatía axilar derecha. Se realizó una gammagrafía PET/TAC con FDG (FDG PET/TAC) para evaluar metástasis a distancia y para detectar el tumor primario. La biopsia de la adenopatía axilar demostró metástasis por carcinoma de mama. La FDG PET/TAC identificó aumento de captación en la adenopatía axilar derecha, una lesión de densidad de partes blandas con diámetro de 24 mm en la región cervical izquierda con captación de FDG aumentada, captación cervical aumentada y en una adenopatía inguinal izquierda. La RNM y la ecografía pélvicas fueron negativas para malignidad. La biopsia de la lesión en cérvix se informó de tumor trofoblástico epitelioide. Clínicamente, el tumor no se sospechó por la ausencia de signos como el sangrado vaginal anómalo. La FDG PET/TAC descubrió la lesión primaria en el cérvix. En este caso clínico, presentamos un raro tumor trofoblástico epitelioide detectado por FDG PET/TAC sincrónico con un cáncer de mama.

Palabras clave:
Tumor trofoblástico epitelioide
FDG PET/TAC
Adenopatía axilar
Cáncer de mama

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