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Vol. 52. Issue 4.
Pages 246-249 (October - December 2019)
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Vol. 52. Issue 4.
Pages 246-249 (October - December 2019)
Brief report
Reactive lymphoid hyperplasia of the liver. A case report
Hiperplasia linfoide reactiva hepática. Reporte de un caso
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64
María Luisa Suárez-Solísa,
Corresponding author
mariasuarezsolis@gmail.com

Corresponding author.
, Sofía de la Sernab, José Manuel Espejo Domínguezc, Luis Ortega Medinaa
a Department of Surgical Pathology, Clínico San Carlos Hospital, 28040 Madrid, Spain
b Department of General Surgery, Clínico San Carlos Hospital, 28040 Madrid, Spain
c Department of Radiology, Clínico San Carlos Hospital, 28040 Madrid, Spain
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Abstract

Reactive lymphoid hyperplasia of the liver is an unusual benign lesion of unknown pathogenesis. The largest reported series to date includes only 7 cases.

Reactive lymphoid hyperplasia can be radiologically confused with malignant tumors such as hepatocellular carcinoma or metastases. Histological differential diagnosis should be chiefly made with lymphomas, Castleman disease and primary biliary cirrhosis.

We report the clinicopathological findings in a 54-year-old woman with an incidental hepatic lesion when she consulted for hematuria. After histological, immunohistochemical and molecular studies, the diagnosis of reactive lymphoid hyperplasia was made.

Keywords:
Reactive lymphoid hyperplasia
Hepatic pseudolymphoma
Nodular lymphoid hyperplasia
Liver lymphoid lesion
Abbreviations:
RLH
TC
US
MRI
HV-CD
HHV-8
EBV-LMP
PCR
PBC
Resumen

La hiperplasia linfoide reactiva hepática es una lesión benigna poco frecuente, de etiopatogenia desconocida. La serie más grande reportada hasta la fecha incluye únicamente 7 casos.

La hiperplasia linfoide reactiva puede confundirse radiológicamente con tumores malignos como el carcinoma hepatocelular o con metástasis. El diagnóstico diferencial desde un punto de vista histológico debe realizarse principalmente con linfomas, la enfermedad de Castleman y la cirrosis biliar primaria.

En este artículo presentamos los hallazgos clínico-patológicos en una mujer de 54 años con una lesión hepática hallada de forma incidental cuando la paciente consultó por hematuria. Tras el estudio histológico, inmunohistoquímico y molecular de la lesión, se diagnosticó de hiperplasia linfoide reactiva.

Palabras clave:
Hiperplasia linfoide reactiva
Seudolinfoma hepático
Hiperplasia nodular linfoide
Lesión linfoide hepática

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