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Obituary
Donald WR Mackenzie (1929–2017)
Roderick Hay
Kings College London, UK
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall"><elsevierMultimedia ident="fig0005"></elsevierMultimedia></p><p id="par0010" class="elsevierStylePara elsevierViewall">Donald Mackenzie was a distinguished medical mycologist whose long career spanned work in Northern Ireland&#44; New York and London&#46; He was born in Edinburgh and his warmth for his home land remained undiminished throughout his life&#46; A keen athlete&#44; he represented Scotland in the javelin in his early 20s but as his career advanced&#44; he developed a keen interest in golf&#44; becoming after retirement a staunch member of the Woburn golf club&#44; where his humour and companionship made him many friends&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">Entering the relatively unexplored word of medical mycology as a young postgraduate was a bold decision&#46; At that time&#44; in the late 1950s&#44; when Donald graduated from Edinburgh University with a PhD on Studies on the biology of pathogenic fungi&#44; mycology was regarded as a remote&#44; arcane branch of medical microbiology&#46; Nonetheless&#44; it was a science where he excelled&#46; His first academic job as a lecturer in medical microbiology in Queens University Belfast in 1959 led him to investigate a large outbreak of scalp ringworm&#46; He developed from the earliest stages a clear understanding that his work on pathogenic fungi was there to benefit patients&#44; and in the course of his investigations&#44; he developed the brush technique for sampling scalp infections and first pointed out the problems associated with eliminating <span class="elsevierStyleItalic">Trichophyton tonsurans</span> from endemic foci of infection&#46; His work was broader than this&#44; encompassing all the mycoses seen in Belfast&#44; information which he reported regularly in the scientific literature&#46; From Belfast&#44; Donald went to Cornell University&#44; New York&#44; USA&#44; in 1967&#44; where he extended his interest in medical mycology to a much wider range of deep fungal infections&#46; Here&#44; he developed a particular interest in the morphogenesis of <span class="elsevierStyleItalic">Candida</span> species during infection&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">He returned to the UK in 1972 when he was appointed Director of the Mycology Reference Laboratory &#40;MRL&#41; of the Public Health Laboratory Service &#40;PHLS&#41; located at the London School of Hygiene and Tropical Medicine &#40;LSHTM&#41;&#46; Here&#44; he combined his scientific interest in investigating and assessing new diagnostic methods&#44; from counterimmunoelectrophoresis and antigen detection to early molecular studies of dermatophyte taxonomy&#46; He developed a wide clinical diagnostic partnership with microbiology laboratories both in the UK and elsewhere&#46; He had a stream of overseas visitors from Nigeria&#44; Venezuela&#44; France&#44; Iran&#44; Spain&#44; New Zealand&#44; the USA and Sudan &#8211; to mention but a few &#8211; who spent time in the MRL and were welcomed into his small but highly active diagnostic laboratory&#46; He developed the first mycological collaboration with the World Health Organisation on zoonotic ringworm&#46; He took an almost impish delight in slightly off-centre ideas &#8211; fungal viruses and erythrocyte binding of fungal antigens brought a little gleam to his eye&#46; He taught students on the Diploma of Bacteriology and MSc in Medical Microbiology courses in LSHTM and lectured widely in the UK and Europe&#46; His contributions to the Revista Iberoamericana de Micolog&#237;a and the Asociaci&#243;n Espa&#241;ola de Micolog&#237;a were deeply appreciated as well as his long association with Spanish mycologists and many colleagues in Latin America&#44; many of whom spent time in his laboratory&#46; Towards the end of his career&#44; there were major changes in the organisation of the PHLS and his laboratory moved to Colindale in North London where he continued his work&#46; He made no secret of his belief that the move had distanced him from clinical colleagues and students&#44; both of whom he considered essential for fostering and maintaining scientific and diagnostic progress&#46; He was appointed Visiting Professor at LSHTM in 1978&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">To restrict any description of Donald&#39;s life to his scientific work would be to pour a half measure&#46; He was tremendous company&#46; His repertoire of stories&#44; tall and otherwise&#44; as well as jokes seemed limitless&#46; All were delivered with a deadpan expression followed in a few minutes by a gentle smile&#46; He was a key member of a large and growing group of international mycologists&#44; becoming the General Secretary &#40;1982&#8211;1987&#41; and then President &#40;1988&#8211;1991&#41; of the International Society of Human and Animal Mycology&#46; Medical Mycology was small enough&#44; yet with the impact of HIV&#47;AIDS and organ transplantation raising the profile of fungal disease&#44; also important enough for this lively international collaboration to play an important role in the changing face of acute medicine&#46; He was also President of the British Society for Medical Mycology &#40;1991&#8211;1994&#41;&#44; having been one of its leading lights for many years&#44; participating in the early initiative by the Medical Research Council to strengthen Medical Mycology in the UK&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">Donald leaves a widow&#44; Joyce&#44; who has been a steadfast and sure support throughout his life but even more so in his later years when declining health from Parkinson&#39;s disease restricted his activity&#59; although in characteristic form&#44; he made light of this encumbrance&#46; He has three children&#58; Peter&#44; Fiona and Jeremy and 9 grandchildren&#46; He will be greatly missed by his family and his many scientific friends and colleagues&#46; We remember him as an ingenious&#44; hospitable and warm man who made wherever he worked an exciting and challenging place to be&#46;</p></span>"
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Article information
ISSN: 11301406
Original language: English
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