Article information
Abstract
It has been demonstrated that persons with Down syndrome (DS) develop neuropathological characteristics of Alzheimer's disease (AD) after the age of 40. Surprisingly, not all these patients will show clinical symptoms of dementia. This article is a review of the criteria currently used for diagnosis and includes a description of how dementia symptoms manifest in individuals with DS.
Keywords:
Alzheimer's disease
Dementia
Down syndrome
Aging
Neuropsychology
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