Letter to the Editor
The comprehensive treatment of delusional disorder
El tratamiento integral del trastorno delirante
Read
6169
Timeswas read the article
1021
Total PDF
5148
Total HTML
Share statistics
array:23 [ "pii" => "S2173505017300602" "issn" => "21735050" "doi" => "10.1016/j.rpsmen.2017.10.007" "estado" => "S300" "fechaPublicacion" => "2017-10-01" "aid" => "363" "copyright" => "SEP y SEPB" "copyrightAnyo" => "2017" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "cor" "cita" => "Rev Psiquiatr Salud Ment. 2017;10:221-3" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1664 "formatos" => array:3 [ "EPUB" => 2 "HTML" => 1369 "PDF" => 293 ] ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S1888989117300484" "issn" => "18889891" "doi" => "10.1016/j.rpsm.2017.03.003" "estado" => "S300" "fechaPublicacion" => "2017-10-01" "aid" => "363" "copyright" => "SEP y SEPB" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "cor" "cita" => "Rev Psiquiatr Salud Ment. 2017;10:221-3" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 8104 "formatos" => array:2 [ "HTML" => 7179 "PDF" => 925 ] ] "es" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Carta al Director</span>" "titulo" => "El tratamiento integral del trastorno delirante" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "221" "paginaFinal" => "223" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "The comprehensive treatment of delusional disorder" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "José E. Muñoz-Negro, Jorge A. Cervilla" "autores" => array:2 [ 0 => array:2 [ "nombre" => "José E." "apellidos" => "Muñoz-Negro" ] 1 => array:2 [ "nombre" => "Jorge A." "apellidos" => "Cervilla" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S2173505017300602" "doi" => "10.1016/j.rpsmen.2017.10.007" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173505017300602?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1888989117300484?idApp=UINPBA00004N" "url" => "/18889891/0000001000000004/v1_201710220524/S1888989117300484/v1_201710220524/es/main.assets" ] ] "itemAnterior" => array:19 [ "pii" => "S2173505017300559" "issn" => "21735050" "doi" => "10.1016/j.rpsmen.2017.10.002" "estado" => "S300" "fechaPublicacion" => "2017-10-01" "aid" => "370" "copyright" => "SEP y SEPB" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "cor" "cita" => "Rev Psiquiatr Salud Ment. 2017;10:221" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 354 "formatos" => array:2 [ "HTML" => 245 "PDF" => 109 ] ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "Construct validity or validity based on the construct?: Comments to Soler et al." "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "221" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "¿Validez de constructo o validez basada en el constructo?: comentarios a Soler et al." ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "José Luis Ventura-León" "autores" => array:1 [ 0 => array:2 [ "nombre" => "José Luis" "apellidos" => "Ventura-León" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S1888989117300745" "doi" => "10.1016/j.rpsm.2017.05.003" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1888989117300745?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173505017300559?idApp=UINPBA00004N" "url" => "/21735050/0000001000000004/v1_201711201721/S2173505017300559/v1_201711201721/en/main.assets" ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "The comprehensive treatment of delusional disorder" "tieneTextoCompleto" => true "saludo" => "Dear Editor," "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "221" "paginaFinal" => "223" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "José E. Muñoz-Negro, Jorge A. Cervilla" "autores" => array:2 [ 0 => array:4 [ "nombre" => "José E." "apellidos" => "Muñoz-Negro" "email" => array:1 [ 0 => "jemunoznegro@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "Jorge A." "apellidos" => "Cervilla" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "UGC de Salud Mental, Complejo Hospitalario Universitario de Granada, Servicio Andaluz de Salud, Granada, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Departamento de Psiquiatría, Facultad de Medicina, Universidad de Granada, Granada, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "El tratamiento integral del trastorno delirante" ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">The ethical principles which govern medical practice, in this case psychiatry, underline the need for patients to be treated as comprehensively as possible, as is demanded by the principles of care, dignity, integrity and justice.<a class="elsevierStyleCrossRef" href="#bib0105"><span class="elsevierStyleSup">1</span></a> In spite of the fact that the prevalence of delusional disorder (DD) stands at 0.18% of the population<a class="elsevierStyleCrossRef" href="#bib0110"><span class="elsevierStyleSup">2</span></a> there are no clinical practice guides (CPG) for DD which guide its treatment, so that the information from the schizophrenia CPG is used instead. This may be due to the fact that its place in psychiatric hospital care has not been clearly defined to date, as it has varied between being considered a schizophrenia subtype,<a class="elsevierStyleCrossRef" href="#bib0115"><span class="elsevierStyleSup">3</span></a> an affective disorder<a class="elsevierStyleCrossRef" href="#bib0120"><span class="elsevierStyleSup">4</span></a> or a separate entity.<a class="elsevierStyleCrossRef" href="#bib0125"><span class="elsevierStyleSup">5</span></a> It is now defined in the CIE-10<a class="elsevierStyleCrossRef" href="#bib0130"><span class="elsevierStyleSup">6</span></a> as a psychosis involving persistent delirious ideas, although functioning is relatively well conserved, while there may also be a few other psychotic symptoms such as negative symptoms and minor hallucinations. Nevertheless, recent studies not only contribute to establishing this disorder as a differentiated entity,<a class="elsevierStyleCrossRefs" href="#bib0135"><span class="elsevierStyleSup">7–11</span></a> as they also rule out the possibility that it is a monosymptomatic disorder<a class="elsevierStyleCrossRef" href="#bib0160"><span class="elsevierStyleSup">12</span></a> and emphasise the existence of different dimensions of the same, as well as its high comorbidity. Although the delirious symptom is not specific to DD, which therefore justifies its inclusion within the psychotic spectrum,<a class="elsevierStyleCrossRef" href="#bib0165"><span class="elsevierStyleSup">13</span></a> it has been shown to have certain specific qualities and characteristics which differentiate it from schizophrenia. Thus while DD would display fewer delirious ideas than is the case in schizophrenia, they would be more intense. There would also be certain qualitative differences respecting schizophrenia. The predominance of somatic or jealous delirious ideas would be intrinsic to DD in comparison with those profiles which predominantly display religious delirious ideas that would be characteristic of schizophrenia.<a class="elsevierStyleCrossRef" href="#bib0135"><span class="elsevierStyleSup">7</span></a> The other dimensions of DD underline not only the role of delirious ideas but also the relevant importance of affective symptoms, especially depression,<a class="elsevierStyleCrossRefs" href="#bib0140"><span class="elsevierStyleSup">8,9,13</span></a> cognitive symptoms<a class="elsevierStyleCrossRefs" href="#bib0145"><span class="elsevierStyleSup">9,13,14</span></a> or the risk of suicide as a comorbidity.<a class="elsevierStyleCrossRef" href="#bib0175"><span class="elsevierStyleSup">15</span></a> Likewise, poorer awareness of the disease has also been detected, or even a worse response to antipsychotic drugs than is the case in schizophrenia.<a class="elsevierStyleCrossRef" href="#bib0135"><span class="elsevierStyleSup">7</span></a> All of these factors mean that this disorder has its own peculiarities and profile which make it necessary treat it more widely than the delirious symptom alone or merely to extrapolate from data on schizophrenia treatments.</p><p id="par0010" class="elsevierStylePara elsevierViewall">Pharmacological treatment is currently considered to be standard for the treatment of DD, and antipsychotic drugs are the cornerstone of this. A recent systemic review of descriptive studies which cover 385 DD patient cases treated using drugs<a class="elsevierStyleCrossRef" href="#bib0180"><span class="elsevierStyleSup">16</span></a> has shown these to be effective, as there is a ≥50% improvement over the basal situation in 33.6% of cases, while first generation antipsychotics (FGA) are superior to second generation ones (SGA) (FGA 39% vs SGA 28%; <span class="elsevierStyleItalic">χ</span><span class="elsevierStyleSup">2</span><span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>5.2595; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>≤<span class="elsevierStyleHsp" style=""></span>.02; RR: 1.40; IC 95%: 1.04–1.88), while no specific individual antipsychotic is superior any other. More data are required on the latest antipsychotic drugs, given that the majority of the data on SGA refer to Risperidone or Olanzapine, while it would be of interest to determine the role of antipsychotic drugs which have an outstanding mood regulating function, as is the case for Quetiapine, or good tolerability such as Aripiprazol. Antidepressive drugs too may play a promising role in treatment, given the importance of the above-mentioned depressive dimension and other symptoms such as anxiety or irritability, as well as the good overall response to them which has been found. This is better than the response to antipsychotic drugs (response ≥50% in 50% of cases), although the sample size was small. They may be especially useful in the somatic subtype.<a class="elsevierStyleCrossRef" href="#bib0180"><span class="elsevierStyleSup">16</span></a> Patient lack of awareness of the disease and possible lack of adherence also suggest a role for prolonged liberation parenteral drugs as well as the possible role of psychoeducation and psychological therapies aimed at improving the capacity for introspection, awareness of the disease and adherence. Cognitive-behavioural therapy has also been shown to have a moderate effect in improving secondary variables such as the social self-esteem of these patients.<a class="elsevierStyleCrossRef" href="#bib0185"><span class="elsevierStyleSup">17</span></a> It would also be necessary to study the potential of treatments of this type or other psychological treatments such as metacognitive training on the cognitive traits underlying the delirious ideas which characterise DD, or cognitive repair<a class="elsevierStyleCrossRef" href="#bib0190"><span class="elsevierStyleSup">18</span></a> of the cognitive symptoms existing in the disorder. To conclude, we emphasise that given that the intrinsic profile of the disorder is becoming increasingly consolidated, studies and especially clinical trials or large-scale naturalistic studies are necessary to study the treatment of DD as a differentiated entity rather than a schizophrenia sub-group under the heading of “other psychoses”.</p><p id="par0015" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleItalic">Transparency declaration</span>: the main author, José Eduardo Muñoz Negro, declares this manuscript to be an honest, accurate and transparent description of the study presented, that no important aspect of the study or studies described has been omitted, and that differences respecting the study initially planned have been explained (and if they are relevant, registered).<a class="elsevierStyleCrossRefs" href="#bib0195"><span class="elsevierStyleSup">19,20</span></a></p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Muñoz-Negro JE, Cervilla JA. El tratamiento integral del trastorno delirante. Rev Psiquiatr Salud Ment (Barc). 2017;10:221–223.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:20 [ 0 => array:3 [ "identificador" => "bib0105" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Tendencias y necesidad clínica de los principios éticos" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "F. Lolas-Stepke" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Rev Psiquiatr Salud Ment (Barc)" "fecha" => "2015" "volumen" => "8" "paginaInicial" => "1" "paginaFinal" => "2" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0110" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lifetime prevalence of psychotic and bipolar I disorders in a general population" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J. Perala" 1 => "J. Suvisaari" 2 => "S.I. Saarni" 3 => "K. Kuoppasalmi" 4 => "E. Isometsa" 5 => "S. Pirkola" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1001/archpsyc.64.1.19" "Revista" => array:6 [ "tituloSerie" => "Arch Gen Psychiatry" "fecha" => "2007" "volumen" => "64" "paginaInicial" => "19" "paginaFinal" => "28" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17199051" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0115" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Dementia praecox oder Gruppe der Schizophrenien" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "E. Bleuler" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:2 [ "titulo" => "Handbuch der Psychiatrie" "serieFecha" => "1911" ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0120" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A textbook of psychiatry for students and practitioners" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "D. Henderson" 1 => "R. Gillespie" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:3 [ "fecha" => "1994" "editorial" => "Oxford University Press" "editorialLocalizacion" => "London" ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0125" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lehrbuch der Psychiatrie" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "E. Kraepelin" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:4 [ "edicion" => "8th ed." "fecha" => "1909–1913" "editorial" => "Barth" "editorialLocalizacion" => "Leipzig" ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0130" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "ICD-10 classification of mental and behavioural disorders. Diagnostic criteria for research 1993" "autores" => array:1 [ 0 => array:2 [ "colaboracion" => "WHO" "etal" => false ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:3 [ "fecha" => "1993" "editorial" => "WHO" "editorialLocalizacion" => "Geneva, Switzerland" ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0135" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Delusional disorder and schizophrenia: a comparative study across multiple domains" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "V. Peralta" 1 => "M.J. Cuesta" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1017/S0033291716001501" "Revista" => array:6 [ "tituloSerie" => "Psychol Med" "fecha" => "2016" "volumen" => "46" "paginaInicial" => "2829" "paginaFinal" => "2839" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27468631" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0140" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Factor analysis of delusional disorder symptomatology" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "A. Serretti" 1 => "E. Lattuada" 2 => "C. Cusin" 3 => "E. Smeraldi" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Compr Psychiatry" "fecha" => "1999" "volumen" => "40" "paginaInicial" => "143" "paginaFinal" => "147" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10080261" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0145" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Empirical redefinition of delusional disorder and its phenomenology: the DELIREMP study" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "E. De Portugal" 1 => "N. González" 2 => "V. del Amo" 3 => "J.M. Haro" 4 => "C.M. Díaz-Caneja" 5 => "J. de Dios Luna del Castillo" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.comppsych.2012.08.002" "Revista" => array:6 [ "tituloSerie" => "Compr Psychiatry" "fecha" => "2013" "volumen" => "54" "paginaInicial" => "243" "paginaFinal" => "255" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23021895" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib0150" "etiqueta" => "10" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Delusional disorders – are they simply paranoid schizophrenia?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "A. Marneros" 1 => "F. Pillmann" 2 => "T. Wustmann" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1093/schbul/sbq125" "Revista" => array:6 [ "tituloSerie" => "Schizophr Bull" "fecha" => "2012" "volumen" => "38" "paginaInicial" => "561" "paginaFinal" => "568" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21078814" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib0155" "etiqueta" => "11" "referencia" => array:1 [ 0 => array:3 [ "comentario" => "[in press]" "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A psychopathological comparison between delusional disorder and schizophrenia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "J.E. Muñoz-Negro" 1 => "I. Ibanez-Casas" 2 => "E. de Portugal" 3 => "V. Lozano-Gutiérrez" 4 => "R. Martínez-Leal" 5 => "J.A. Cervilla" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:2 [ "tituloSerie" => "Can J Psychiatry" "fecha" => "2017" ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib0160" "etiqueta" => "12" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Negative symptoms across psychotic spectrum disorders" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J.E. Muñoz-Negro" 1 => "V. Lozano" 2 => "I. Ibanez-Casas" 3 => "B.G. de la Cruz" 4 => "A. Soler" 5 => "J.A. Alcalá" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Eur J Psychiatry" "fecha" => "2017" "volumen" => "31" "paginaInicial" => "37" "paginaFinal" => "41" ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib0165" "etiqueta" => "13" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A dimensional comparison between delusional disorder, schizophrenia and schizoaffective disorder" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J.E. Muñoz-Negro" 1 => "I. Ibanez-Casas" 2 => "E. de Portugal" 3 => "S. Ochoa" 4 => "M. Dolz" 5 => "J.M. Haro" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.schres.2015.10.039" "Revista" => array:6 [ "tituloSerie" => "Schizophr Res" "fecha" => "2015" "volumen" => "169" "paginaInicial" => "248" "paginaFinal" => "254" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26585220" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib0170" "etiqueta" => "14" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Deficits in executive and memory processes in delusional disorder: a case–control study" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "I. Ibanez-Casas" 1 => "E. de Portugal" 2 => "N. Gonzalez" 3 => "K.A. McKenney" 4 => "J.M. Haro" 5 => "J. Usall" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1371/journal.pone.0067341" "Revista" => array:6 [ "tituloSerie" => "PLOS ONE" "fecha" => "2013" "volumen" => "8" "paginaInicial" => "e67341" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23844005" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0883944114004821" "estado" => "S300" "issn" => "08839441" ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib0175" "etiqueta" => "15" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Suicidal ideation and suicidal behaviour in delusional disorder: a clinical overview" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "A. González-Rodríguez" 1 => "O. Molina-Andreu" 2 => "V. Navarro Odriozola" 3 => "C. Gastó Ferrer" 4 => "R. Penadés" 5 => "R. Catalán" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1155/2014/834901" "Revista" => array:5 [ "tituloSerie" => "Psychiatry J" "fecha" => "2014" "volumen" => "2014" "paginaInicial" => "834901" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24829903" "web" => "Medline" ] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib0180" "etiqueta" => "16" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A systematic review on the pharmacological treatment of delusional disorder" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "J.E. Muñoz-Negro" 1 => "J.A. Cervilla" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/JCP.0000000000000595" "Revista" => array:6 [ "tituloSerie" => "J Clin Psychopharmacol" "fecha" => "2016" "volumen" => "36" "paginaInicial" => "684" "paginaFinal" => "690" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27811554" "web" => "Medline" ] ] ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib0185" "etiqueta" => "17" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Treatments for delusional disorder" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "M. Skelton" 1 => "W.A. Khokhar" 2 => "S.P. Thacker" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1093/schbul/sbv080" "Revista" => array:6 [ "tituloSerie" => "Schizophr Bull" "fecha" => "2015" "volumen" => "41" "paginaInicial" => "1010" "paginaFinal" => "1012" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26209547" "web" => "Medline" ] ] ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib0190" "etiqueta" => "18" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Therapeutic approach to delusional disorder based on psychopathological complexity: proposal for a decision model" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "A. González-Rodríguez" 1 => "O. Molina-Andreu" 2 => "R. Penadés" 3 => "M. Bernardo" 4 => "R. Catalán" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/JCP.0000000000000289" "Revista" => array:6 [ "tituloSerie" => "J Clin Psychopharmacol" "fecha" => "2015" "volumen" => "35" "paginaInicial" => "201" "paginaFinal" => "202" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25679132" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib0195" "etiqueta" => "19" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Improving transparency of scientific reporting to increase value and reduce waste in mental health research" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "F. Catalá-López" 1 => "D. Moher" 2 => "R. Tabarés-Seisdedos" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Rev Psiquiatr Salud Ment (Barc)" "fecha" => "2016" "volumen" => "9" "paginaInicial" => "1" "paginaFinal" => "3" ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib0200" "etiqueta" => "20" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Declaración de transparencia: un paso hacia la presentación completa de artículos de investigación" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "F. Catalá-López" 1 => "B. Hutton" 2 => "M.J. Page" 3 => "E. Vieta" 4 => "R. Tabarés-Seisdedos" 5 => "D. Moher" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Rev Psiquiatr Salud Ment (Barc)" "fecha" => "2016" "volumen" => "9" "paginaInicial" => "63" "paginaFinal" => "64" ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/21735050/0000001000000004/v1_201711201721/S2173505017300602/v1_201711201721/en/main.assets" "Apartado" => array:4 [ "identificador" => "7636" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Letters to the Editor" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/21735050/0000001000000004/v1_201711201721/S2173505017300602/v1_201711201721/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173505017300602?idApp=UINPBA00004N" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 October | 14 | 1 | 15 |
| 2024 September | 36 | 4 | 40 |
| 2024 August | 29 | 2 | 31 |
| 2024 July | 38 | 2 | 40 |
| 2024 June | 19 | 2 | 21 |
| 2024 May | 12 | 4 | 16 |
| 2024 April | 28 | 5 | 33 |
| 2024 March | 22 | 6 | 28 |
| 2024 February | 20 | 7 | 27 |
| 2024 January | 32 | 11 | 43 |
| 2023 December | 16 | 4 | 20 |
| 2023 November | 22 | 7 | 29 |
| 2023 October | 31 | 4 | 35 |
| 2023 September | 21 | 6 | 27 |
| 2023 August | 21 | 0 | 21 |
| 2023 July | 9 | 4 | 13 |
| 2023 June | 30 | 3 | 33 |
| 2023 May | 38 | 6 | 44 |
| 2023 April | 44 | 5 | 49 |
| 2023 March | 40 | 9 | 49 |
| 2023 February | 29 | 2 | 31 |
| 2023 January | 19 | 3 | 22 |
| 2022 December | 26 | 4 | 30 |
| 2022 November | 23 | 12 | 35 |
| 2022 October | 37 | 13 | 50 |
| 2022 September | 37 | 6 | 43 |
| 2022 August | 31 | 6 | 37 |
| 2022 July | 35 | 15 | 50 |
| 2022 June | 29 | 9 | 38 |
| 2022 May | 22 | 10 | 32 |
| 2022 April | 33 | 7 | 40 |
| 2022 March | 45 | 6 | 51 |
| 2022 February | 41 | 15 | 56 |
| 2022 January | 76 | 15 | 91 |
| 2021 December | 76 | 20 | 96 |
| 2021 November | 78 | 27 | 105 |
| 2021 October | 104 | 41 | 145 |
| 2021 September | 66 | 21 | 87 |
| 2021 August | 115 | 8 | 123 |
| 2021 July | 87 | 22 | 109 |
| 2021 June | 59 | 29 | 88 |
| 2021 May | 668 | 20 | 688 |
| 2021 April | 326 | 52 | 378 |
| 2021 March | 158 | 24 | 182 |
| 2021 February | 143 | 28 | 171 |
| 2021 January | 93 | 27 | 120 |
| 2020 December | 84 | 17 | 101 |
| 2020 November | 119 | 18 | 137 |
| 2020 October | 68 | 13 | 81 |
| 2020 September | 65 | 16 | 81 |
| 2020 August | 76 | 16 | 92 |
| 2020 July | 96 | 19 | 115 |
| 2020 June | 42 | 33 | 75 |
| 2020 May | 72 | 27 | 99 |
| 2020 April | 99 | 18 | 117 |
| 2020 March | 54 | 12 | 66 |
| 2020 February | 74 | 23 | 97 |
| 2020 January | 75 | 11 | 86 |
| 2019 December | 66 | 19 | 85 |
| 2019 November | 326 | 8 | 334 |
| 2019 October | 38 | 20 | 58 |
| 2019 September | 55 | 17 | 72 |
| 2019 August | 222 | 19 | 241 |
| 2019 July | 77 | 20 | 97 |
| 2019 June | 61 | 19 | 80 |
| 2019 May | 126 | 37 | 163 |
| 2019 April | 42 | 13 | 55 |
| 2019 March | 31 | 8 | 39 |
| 2019 February | 19 | 9 | 28 |
| 2019 January | 38 | 22 | 60 |
| 2018 December | 25 | 7 | 32 |
| 2018 November | 37 | 10 | 47 |
| 2018 October | 18 | 9 | 27 |
| 2018 September | 10 | 12 | 22 |
| 2018 August | 8 | 3 | 11 |
| 2018 July | 10 | 5 | 15 |
| 2018 June | 17 | 3 | 20 |
| 2018 May | 13 | 1 | 14 |
| 2018 April | 6 | 3 | 9 |
| 2018 March | 1 | 0 | 1 |
Show all