Article information
Resumen
Este artículo revisa la asociación entre el antecedente de una fractura de Colles y la existencia de osteoporosis en mujeres, tanto en la zona de la fractura como en las otras localizaciones clinicamente relevantes. Del examen de la bibliografía se desprende que tanto desde el punto de vista fisiopatológico como epidemiológico existe una clara relación. Así, las pacientes con fractura de Colles presentan no sólo una menor masa ósea que los controles en todas las zonas estudiadas, sino también una mayor frecuencia de otras fracturas osteoporóticas, ya sean vertebrales o periféricas incluyendo las femorales. Esta asociación, también evidenciada en estudios genéticos y de agregación familiar, es más evidente en las pacientes posmenopáusicas jóvenes. Es decir, las mujeres menores de 65 años que hayan presentado una fractura de Colles merecen especial atención por ser, dicha fractura, el aviso de una osteoporosis generalizada subyacente.
Palabras clave:
Fractura de Colles
Osteoporosis
Mujeres
Densidad mineral ósea
Abstract
In this paper the association between Colles’ fracture and generalized osteoporosis in women is revisited. It seems clear from the literature review that an epidemiological and physiopathological relationship exist among these entities. Women who had suffered a Colles’ fracture not only show a diminished bone mineral density when compared to controls at all relevant osteoporotic areas, they also have more frequently vertebral and hip fractures. Genetic studies and family pedigree surveys have confirmed this association. It is noteworthy that younger postmenopausal women, usually younger than 65 years of age, show the stronger relationship. Thus, all postmenopausal women with an history of Colles’ fracture, and specifically those under 65 years, should be evulated in order to rule out an underlying osteoporosis.
Key words:
Colle's fracture
Osteoporosis women
Bone mineral density
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