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array:18 [ "pii" => "13143413" "issn" => "02104806" "estado" => "S300" "fechaPublicacion" => "2008-09-01" "documento" => "article" "subdocumento" => "fla" "cita" => "Actas Urol Esp. 2008;32:811-20" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1029 "formatos" => array:3 [ "EPUB" => 7 "HTML" => 787 "PDF" => 235 ] ] "itemSiguiente" => array:14 [ "pii" => "13143412" "issn" => "02104806" "estado" => "S300" "fechaPublicacion" => "2008-09-01" "documento" => "article" "subdocumento" => "fla" "cita" => "Actas Urol Esp. 2008;32:821-6" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 952 "formatos" => array:3 [ "EPUB" => 7 "HTML" => 696 "PDF" => 249 ] ] "es" => array:9 [ "idiomaDefecto" => true "titulo" => "Valoración de la eficacia de la malla de polipropileno en la reparación delprolapso urogenital en 106 pacientes" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "821" "paginaFinal" => "826" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "I Zapardiel Gutiérrez, J De la Fuente Valero, S Iniesta Pérez, J Botija Botija, T Pérez Medina, JM. Bajo Arenas" "autores" => array:6 [ 0 => array:2 [ "Iniciales" => "I" "apellidos" => "Zapardiel Gutiérrez" ] 1 => array:2 [ "Iniciales" => "J" "apellidos" => "De la Fuente Valero" ] 2 => array:2 [ "Iniciales" => "S" "apellidos" => "Iniesta Pérez" ] 3 => array:2 [ "Iniciales" => "J" "apellidos" => "Botija Botija" ] 4 => array:2 [ "Iniciales" => "T" "apellidos" => "Pérez Medina" ] 5 => array:2 [ "Iniciales" => "JM." "apellidos" => "Bajo Arenas" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/13143412?idApp=UINPBA00004N" "url" => "/02104806/0000003200000008/v0_201607111123/13143412/v0_201607111126/es/main.assets" ] "itemAnterior" => array:14 [ "pii" => "13143414" "issn" => "02104806" "estado" => "S300" "fechaPublicacion" => "2008-09-01" "documento" => "article" "subdocumento" => "fla" "cita" => "Actas Urol Esp. 2008;32:806-10" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1079 "formatos" => array:3 [ "EPUB" => 7 "HTML" => 827 "PDF" => 245 ] ] "es" => array:9 [ "idiomaDefecto" => true "titulo" => "Carcinoma urotelial plasmocitoide de vejiga urinaria.Estudio de 7 casos" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "806" "paginaFinal" => "810" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "A Gaafar, M Garmendia, E de Miguel, V Velasco, A Ugalde, FJ Bilbao, G de Petris, JI. López" "autores" => array:8 [ 0 => array:2 [ "Iniciales" => "A" "apellidos" => "Gaafar" ] 1 => array:2 [ "Iniciales" => "M" "apellidos" => "Garmendia" ] 2 => array:2 [ "Iniciales" => "E" "apellidos" => "de Miguel" ] 3 => array:2 [ "Iniciales" => "V" "apellidos" => "Velasco" ] 4 => array:2 [ "Iniciales" => "A" "apellidos" => "Ugalde" ] 5 => array:2 [ "Iniciales" => "FJ" "apellidos" => "Bilbao" ] 6 => array:2 [ "Iniciales" => "G" "apellidos" => "de Petris" ] 7 => array:2 [ "Iniciales" => "JI." "apellidos" => "López" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/13143414?idApp=UINPBA00004N" "url" => "/02104806/0000003200000008/v0_201607111123/13143414/v0_201607111125/es/main.assets" ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Efecto terapéutico de Mitomicina C en el postoperatorio inmediato depacientes con tumores vesicales no músculo invasores de bajo riesgo" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "811" "paginaFinal" => "820" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "A Jalón Monzón, JM Fernández Gómez, S Escaf Bramada, M Álvarez Múgica, J García Rodríguez, FJ. Regadera Sejas" "autores" => array:6 [ 0 => array:3 [ "Iniciales" => "A" "apellidos" => "Jalón Monzón" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "affa" ] ] ] 1 => array:3 [ "Iniciales" => "JM" "apellidos" => "Fernández Gómez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "affa" ] ] ] 2 => array:3 [ "Iniciales" => "S" "apellidos" => "Escaf Bramada" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "affa" ] ] ] 3 => array:3 [ "Iniciales" => "M" "apellidos" => "Álvarez Múgica" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "affa" ] ] ] 4 => array:3 [ "Iniciales" => "J" "apellidos" => "García Rodríguez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "affa" ] ] ] 5 => array:3 [ "Iniciales" => "FJ." "apellidos" => "Regadera Sejas" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "affa" ] ] ] ] "afiliaciones" => array:1 [ 0 => array:3 [ "entidad" => "Servicio de Urología. Hospital de Jove." "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "affa" ] ] ] ] "pdfFichero" => "292v32n08a13143413pdf001.pdf" "tienePdf" => true "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec689595" "palabras" => array:5 [ 0 => "No músculo-invasor" 1 => "Cáncer vesical" 2 => "Terapia intravesical" 3 => "Quimioterapia" 4 => "Mitomicina C" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec689596" "palabras" => array:5 [ 0 => "Non muscle-invasive" 1 => "Bladder cancer" 2 => "Intravesical therapy" 3 => "Chemotherapy" 4 => "Mitomycin C" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "Introducción: El cáncer vesical es una de las enfermedades con más alta prevalencia entre los distintos tipos de neoplasiadebido a su tendencia a la recidiva. El tratamiento en las etapas iniciales es la resección transuretral (RTU). Sinembargo, después de la RTU de un tumor vesical no músculo invasor, un porcentaje alto recidivarán en 1-2 años. Poresta razón, se ha propuesto la administración de quimioterapia o inmunoterapia adyuvante después de la RTU en unintento de disminuir la recidiva y prevenir la progresión. <br />Pacientes y métodos: Estudio prospectivo, controlado y randomizado. Se incluyeron 100 pacientes con tumores vesicalesno músculo-invasores de bajo riesgo. Todos los pacientes sometidos inicialmente a RTU y posteriormente randomizadospara recibir Mitomicina C (MMC) postoperatoria en dosis única. <br />Resultados: Todos los tumores eran menores de 3 cm. La media de seguimiento fue de 26,43 ± 7,65 meses. Se administróMMC en 49 pacientes, de los cuales el 67,3% no recidivó y el 32,7% lo hicieron como tumor vesical no invasor. Delos 51 pacientes que no recibieron MMC, el 51% no recidivaron, el 47% recidivaron como tumor no invasor y el 2% comotumor invasor. Se encontraron diferencias significativas en cuanto al tiempo libre de enfermedad según se empleara MMCpostoperatoria o nada. <br />Conclusiones: Cuando evaluamos a los pacientes con carcinoma vesical no músculo invasor de bajo riesgo, pertenecientesa un solo centro sanitario y con dosis alta de MMC en dosis única tras la RTU, evidenciamos un mayor tiempolibre de enfermedad estadísticamente significativa frente a los casos en los que no se utilizó ningún tratamiento." ] "en" => array:1 [ "resumen" => "Introductión: Bladder cancer is a disease with a high prevalence due to its recurrence rate. Transurethral resectionof the bladder (TURB) is the treatment in initial stages. Nevertheless, a high percentage of non-muscle-invasive tumorstreated will have a recurrence 1-2 years afterwards. Adjuvant quemotherapy or immunotherapy after TURB has beenadministered in order to decrease the rate of recurrence and to prevent progression. <br />Patients and methods: A prospectived, controlled and randomized study was performed. We included 100 patientswith non-muscle-invasive and bladder tumors the low grade. All patients had initially a TURB performed and were randomizedto either receive or not a single dose mitomycin C (MMC) in the immediate postoperatory. <br />Results: All low grade tumors was less than 3 cm. Mean follow-up was 26,43±7,65 months. MMC was administeredin 49 patients, of these, 67,3% had no recurrence and 32,7% had a non-muscle-invasive recurrence. Of the 51 patientsin the non mitomycin, 51% had no recurrence while 47% had a non-muscle-invasive recurrence, and 2% had a muscleinvasiveprogression. We found significantly differences in time to recurrence among the two groups. Summary: We found a greater time to recurrence in the group of single dose adjuvant MMC being this difference statisticallysignificantly when comparing with the other group. " ] ] ] "idiomaDefecto" => "es" "url" => "/02104806/0000003200000008/v0_201607111123/13143413/v0_201607111125/es/main.assets" "Apartado" => array:4 [ "identificador" => "55588" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Original" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/02104806/0000003200000008/v0_201607111123/13143413/v0_201607111125/es/292v32n08a13143413pdf001.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/13143413?idApp=UINPBA00004N" ]
