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array:23 [ "pii" => "S0210480608739561" "issn" => "02104806" "doi" => "10.1016/S0210-4806(08)73956-1" "estado" => "S300" "fechaPublicacion" => "2008-01-01" "aid" => "73956" "copyright" => "Asociación Española de Urología (AEU)" "copyrightAnyo" => "2008" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Actas Urol Esp. 2008;32:888-93" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1226 "formatos" => array:3 [ "EPUB" => 7 "HTML" => 687 "PDF" => 532 ] ] "itemSiguiente" => array:18 [ "pii" => "S0210480608739573" "issn" => "02104806" "doi" => "10.1016/S0210-4806(08)73957-3" "estado" => "S300" "fechaPublicacion" => "2008-01-01" "aid" => "73957" "copyright" => "Asociación Española de Urología (AEU)" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Actas Urol Esp. 2008;32:894-903" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1360 "formatos" => array:3 [ "EPUB" => 7 "HTML" => 787 "PDF" => 566 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Efecto terapéutico de Mitomicina C en el postoperatorio inmediato de pacientes con tumores vesicales no músculo invasores de riesgo intermedio" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "894" "paginaFinal" => "903" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Therapeutic Effect of Mitomycin C in the Immediate Postoperative Period in Patients with Intermediate-Risk Non-Muscle-Invasive Bladder Tumors." ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "A. 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"apellidos" => "Regadera Sejas" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210480608739573?idApp=UINPBA00004N" "url" => "/02104806/0000003200000009/v1_201304251914/S0210480608739573/v1_201304251914/es/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S021048060873955X" "issn" => "02104806" "doi" => "10.1016/S0210-4806(08)73955-X" "estado" => "S300" "fechaPublicacion" => "2008-01-01" "aid" => "73955" "copyright" => "Asociación Española de Urología (AEU)" "documento" => "article" "crossmark" => 0 "subdocumento" => "rev" "cita" => "Actas Urol Esp. 2008;32:879-87" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1452 "formatos" => array:3 [ "EPUB" => 4 "HTML" => 875 "PDF" => 573 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Linfadenectomía (ampliada vs estándar) y cáncer de próstata" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "879" "paginaFinal" => "887" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Pelvic Lymph Node Dissection (Extended vs Standard) and Prostate Cancer" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "A. Rincón Mayans, J.J. Zudaire Bergera, J. Rioja Zuazu, B. Zudaire Diaz-Tejeiro, J. Barba Abad, X. Brugarolas Rosselló, D. Rosell Costa, J.M. Berián Polo" "autores" => array:8 [ 0 => array:2 [ "nombre" => "A." "apellidos" => "Rincón Mayans" ] 1 => array:2 [ "nombre" => "J.J." "apellidos" => "Zudaire Bergera" ] 2 => array:2 [ "nombre" => "J." "apellidos" => "Rioja Zuazu" ] 3 => array:2 [ "nombre" => "B." "apellidos" => "Zudaire Diaz-Tejeiro" ] 4 => array:2 [ "nombre" => "J." "apellidos" => "Barba Abad" ] 5 => array:2 [ "nombre" => "X." "apellidos" => "Brugarolas Rosselló" ] 6 => array:2 [ "nombre" => "D." "apellidos" => "Rosell Costa" ] 7 => array:2 [ "nombre" => "J.M." "apellidos" => "Berián Polo" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S021048060873955X?idApp=UINPBA00004N" "url" => "/02104806/0000003200000009/v1_201304251914/S021048060873955X/v1_201304251914/es/main.assets" ] "es" => array:14 [ "idiomaDefecto" => true "titulo" => "Serie inicial de prostatectomía radical laparoscópica en un hospital general: revisión y comparativa de series nacionales e internacionales." "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "888" "paginaFinal" => "893" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "M. Crego Tapias, P. Puig Duran, B. Juaneda Castell, J. Segura Forcada, C. Vallejo Gil, L.L. Cortadellas Angel" "autores" => array:6 [ 0 => array:4 [ "nombre" => "M." "apellidos" => "Crego Tapias" "email" => array:1 [ 0 => "marccrego@gmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "P." "apellidos" => "Puig Duran" ] 2 => array:2 [ "nombre" => "B." "apellidos" => "Juaneda Castell" ] 3 => array:2 [ "nombre" => "J." "apellidos" => "Segura Forcada" ] 4 => array:2 [ "nombre" => "C." "apellidos" => "Vallejo Gil" ] 5 => array:2 [ "nombre" => "L.L." "apellidos" => "Cortadellas Angel" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Servicio de Urología. Hospital General de Granollers. Barcelona." ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "1" "correspondencia" => "Correpondencia autor: Dr. M. Crego Tapias Servicio de Urología. Hospital de Granollers Avda. Francesc Ribas, s/n - 08400 Granollers (Barcelona) Tel.: 938 425 000" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Initial Series Of Radical Prostatectomy In A General Hospital: Review And Comparative Of National And International Series" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2008-02-29" "fechaAceptado" => "2008-03-31" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec88717" "palabras" => array:3 [ 0 => "Cáncer próstata" 1 => "Prostatectomía radical" 2 => "Laparoscopia" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec88718" "palabras" => array:3 [ 0 => "Prostate cancer" 1 => "Radical prostatectomy" 2 => "Laparoscopy" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Serie inicial de prostatectomía radical laparoscópica en un hospital general: revisión y comparativa de series nacionales e internacionales.</p> <span class="elsevierStyleSectionTitle">Introducción y objetivos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">La prostatectomía radical laparoscópica es una técnica que ha demostrado unos resultados oncológicos y funcionales competitivos, por lo que se ha convertido en un procedimiento rutinario en muchos centros punteros. No obstante, la dificultad de aprendizaje y su coste inicial, pueden cuestionar su implantación como técnica rutinaria, en centros que no sean de referencia.</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Realizamos un estudio descriptivo de nuestra serie inicial analizando la técnica quirúrgica, resultados posquirúrgicos inmediatos, y oncológicos y funcionales a corto plazo, comparándolos con otras series en centros nacionales e internacionales.</p> <span class="elsevierStyleSectionTitle">Métodos</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">De febrero 2006 a agosto 2007 realizamos 69 procedimientos laparoscópicos en nuestro centro, de los cuales 34 fueron prostatectomías radicales. La edad media de la serie fue de 63 años (50-72), con un peso prostático medio por ecografía transrectal de 35 gr. (17-72), y una mediana de PSA de 6 ng/ml (4-35). Los estadios clínicos fueron: T1c 59%, T2a 12%, T2b 17%, T2c 12%; con Gleason: 2+2 en 3%, 3+3 en 35%, 3+4 en 15%, 4+3 en 44%, 4+5 en 3%.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">De los 34 casos iniciados por laparoscopia, se terminaron 30, con un tiempo quirúrgico medio de 261 minutos (150-380). Se convirtieron 4 casos a cirugía abierta, 1 por enfisema subcutáneo, 1 por prolongación del tiempo quirúrgico, 1 por sangrado, 1 por lesión rectal.</p><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Los estadios patológicos fueron: pT2a 3%, pT2b 18%, pT2c 41%, pT3a 32%, pT3b 6%. Con Gleason de: 3+3 en 26%, 3+4 en 14%, 4+3 en 47%, 4+4 en 9%, 4+5 en 3%. Obtuvimos un 29% de márgenes positivos (50% pT3a, 20% pT3b, 20% pT2b, 10% pT2c).</p><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">La continencia (0-1 compresas) al mes, fue del 62%, llegando al 84% a los 6 meses. La erección al mes, se conservó en un 50% de los pacientes, en los cuatro casos de disección intrafascial.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">la prostatectomía radical laparoscópica es una técnica de difícil aprendizaje, y exige un tiempo quirúrgico inicial superior a la cirugía abierta. No obstante, comprobamos que se trata de una técnica segura, con unos resultados oncológicos y funcionales competitivos, una recuperación temprana y un escaso sangrado, incluso en series iniciales. Por ello, también debería considerarse una opción para el tratamiento del cáncer de próstata en centros de segundo nivel.</p>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span class="elsevierStyleSectionTitle">Introduction and objectives</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">The radical prostatectomy is a technique that has shown competitive oncological and functional results, that is why it has become to be a routine procedure in many leading centers. Nevertheless, the difficulty of learning and its initial cost, could question its implantation as a routine technique in centers that are not a point of reference.</p><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">We have carried out a descriptive study of our initial series analyzing the surgical technique, post surgical immediate results, and oncological and functional short-term outcomes, comparing them with other series in national and international centers.</p> <span class="elsevierStyleSectionTitle">Methods</span><p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">From February, 2006 to August, 2007 we performed 69 laparoscopical procedures in our center, of which 34 were radical prostatectomies. The average age of the series were 63 years (50-72), with a prostate average weight by transrectal ultrasound of 35 gr. (17-72), and a median PSA of 6ng/ml (4-35). The clinical stages were: T1c 59%, T2a 12%, T2b 17%, T2c 12%; with Gleason combined of: 2+2 in 3%, 3+3 in 35%, 3+4 in 15%, 4+3 in 44%, 4+5 in 3%.</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">Out of the 34 cases initiated by laparoscopy, 30 were concluded laparoscopically, with a surgical average time of 261 minutes (150- 380). The pathological stages were: pT2a 3%, pT2b 18%, pT2c 41%, pT3a 32 %, pT3b 6%. With Gleason of: 3+3 in 26%, 3+4 in 14%, 4+3 in 47%, 4+4 in 9%, 4+5 in 3%. We obtained 29 % of positive margins (50% pT3a, 20% pT3b, 20% pT2b, 10% pT2c). Four cases were converted to open surgery, one due to subcutaneous emphysema, one to enlarged surgical time, one bleeding, and one rectal injury.</p><p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">The continence (0-1 pads) at the first month was 62%, reaching 84% at 6 months.</p><p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">The erection, remained in 50% of the patients at the first month, in the four cases of intrafascial dissection.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0075" class="elsevierStyleSimplePara elsevierViewall">Laparoscopic radical prostatectomy is a technique of difficult learning, and initially requires higher surgical time than open surgery.Nevertheless, we prove that it is a reliable technique with competitive oncological and functional results, earlyrecovery and little bleeding even in the initial series. Therefore, it should be considered an option for the treatment of prostate cancer also in not leading centers.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Referencias" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:24 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Laparoscopic nephrectomy: inicial case report" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "R.V. Clayman" 1 => "L.R. Kavousi" 2 => "N.J. Soper" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J. Urol" "fecha" => "1991" "volumen" => "146" "paginaInicial" => "278" "paginaFinal" => "282" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1830346" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2." 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