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García Tello, A. Berenguer Sánchez" "autores" => array:5 [ 0 => array:4 [ "nombre" => "L." "apellidos" => "Llanes González" "email" => array:1 [ 0 => "luis.llanes@yahoo.es" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "M." "apellidos" => "Luján Galán" ] 2 => array:2 [ "nombre" => "N." "apellidos" => "Rodríguez García" ] 3 => array:2 [ "nombre" => "A." "apellidos" => "García Tello" ] 4 => array:2 [ "nombre" => "A." "apellidos" => "Berenguer Sánchez" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Servicio de Urología. Hospital Universitario de Getafe. Madrid" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "1" "correspondencia" => "Correspondencia autor: Dr. L. Llanes González Sarasate, 27 - 28222 Majadahonda. Madrid" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Trends in the incidence of testicular germ cell cancer in a 300.000 inhabitants spanish population (1991-2005)" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2007-11-01" "fechaAceptado" => "2008-04-01" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec88675" "palabras" => array:3 [ 0 => "Neoplasias testiculares" 1 => "Incidencia" 2 => "Epidemiología" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec88676" "palabras" => array:3 [ 0 => "Testicular neoplasms" 1 => "Incidence rate" 2 => "Epidemiology" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Describir las características y tendencia temporal de los cánceres testiculares en un área sanitaria española</p> <span class="elsevierStyleSectionTitle">Material y métodos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Se realizó una búsqueda de todos los pacientes residentes en nuestra área sanitaria diagnosticados de cáncer testicular por primera vez. Se calcularon los datos de incidencia, cambio porcentual anual (APC) según tasa de incidencia ajustada a la población española, edad al diagnóstico y las frecuencias de los diferentes tipos histológicos tumorales</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">La incidencia del cáncer testicular pasó de 0,84/100.000 varones en 1991 a 1,91/100.000 varones en 2005, con un pico de 6,77/100.000 varones en 2003. El cambio porcentual anual (APC) ajustado a la población española se calculó en 2,39%. Por subtipos histológicos, para los seminomas: la tasa de incidencia pasó de 0,84 a 0,64/100.000 (1991-2005), con un pico de 5,41/100,000 en 2003 y un APC ajustado a la población española de 6,06. Para los no seminomas, la tasa de incidencia varió de 1,66 a 1,28/100.000 (1992-2005), con un pico de 3,65/100.000 en 2001 y un APC ajustado a la población española de 12,74. La edad al diagnóstico fue, para los seminomas: media 31,23, DE 8,56, mediana 30; y para los tumores no seminomatosos: media 23,68, DE 6,85, mediana 25. La comparación de las medias de ambas edades resultó estadísticamente significativa (p‹ 0,0001)</p> <span class="elsevierStyleSectionTitle">Discusión</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Existe un aumento de la incidencia del cáncer testicular de células germinales en nuestro medio, tal y como se ha demostrado en otros países</p>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">To describe the features and the time trends of the testicular cancer in a spanish population</p> <span class="elsevierStyleSectionTitle">Materials and methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Data on incident cases of testicular germ cell cancer diagnosed in our population were extracted from the Cancer Registry of our Department. We calculed annual incidence rates of testicular cancer, the Spanish population-adjusted annual percent change (APC), age of diagnosis and the different histologic types frequencies. Results: The overall incidence rate rose from 0.84 per 100,000 males to 1.91 per 100,000 males from 1991 till 2005, with a peak of 6.77 per 100,000 males in 2003. The Spanish population-adjusted APC was 2.39%. By histologic subgroup, for seminomas: the incidence rate varied from 0.84 per 100,000 males to 0.64 per 100,000 (1991-2005), with a peak of 5.41 per 100,000 in 2003 and the Spanish population-adjusted APC was 6.06. For nonseminomas, the incidence rate varied from 1.66 per 100,000 to 1.28 per 100,000 (1992-2005), with a peak of 3.65 per 100.000 in 2001 and the Spanish population-adjusted APC was 12.74. Mean ages were 31.23 years (median 30, SD 8.56) for seminomas, and 23.68 years (median 25, SD 6.85) for nonseminomas, with statistic significance (p‹ 0.0001)</p> <span class="elsevierStyleSectionTitle">Discussion</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">The increasing testicular cancer incidence observed for this population follows the time trends showed in other European countries</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Referencias" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:11 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Estimating average annual percent change for disease rates without assuming constant change" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "M.P. Fay" 1 => "R.C. Tiwari" 2 => "E.J. Feuer" 3 => "Z. 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Tendencia en la incidencia del cáncer testicular de células germinales en un área sanitaria española de 300.000 habitantes (1991-2005)
Trends in the incidence of testicular germ cell cancer in a 300.000 inhabitants spanish population (1991-2005)
L. Llanes González1
, M. Luján Galán, N. Rodríguez García, A. García Tello, A. Berenguer Sánchez
Autor para correspondencia
luis.llanes@yahoo.es
Correspondencia autor: Dr. L. Llanes González Sarasate, 27 - 28222 Majadahonda. Madrid
Correspondencia autor: Dr. L. Llanes González Sarasate, 27 - 28222 Majadahonda. Madrid
Servicio de Urología. Hospital Universitario de Getafe. Madrid