Carcinoma uretral con extensión locorregional importante. ¿cómo manejamos una patología infrecuente?
A. Segura huerta1, J. Molina saera, L. Palomar abad, L. Pellín ariño, A. Guerrero zotano, V. Calderero aragón
Servicio de Oncología Médica. Hospital La Fe. Valencia
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"apellidos" => "Segura huerta" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "J." "apellidos" => "Molina saera" ] 2 => array:2 [ "nombre" => "L." "apellidos" => "Palomar abad" ] 3 => array:2 [ "nombre" => "L." "apellidos" => "Pellín ariño" ] 4 => array:2 [ "nombre" => "A." "apellidos" => "Guerrero zotano" ] 5 => array:2 [ "nombre" => "V." "apellidos" => "Calderero aragón" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Servicio de Oncología Médica. Hospital La Fe. Valencia" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "1" "correspondencia" => "Dr. A. Segura Huerta Servicio de Oncología. Hospital Univ. La Fe Avda. de Campanar, 21 46009 Valencia" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2003-09-02" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec87047" "palabras" => array:4 [ 0 => "Adenocarcinoma uretral" 1 => "Neoplasias uretrales" 2 => "Tratamiento" 3 => "Quimioterapia" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec87048" "palabras" => array:4 [ 0 => "Urethral adenocarcinoma" 1 => "Urethral cancer" 2 => "Treatment" 3 => "Chemotherapy" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span class="elsevierStyleSectionTitle">Carcinoma uretral con extensión locorregional importante. ¿cómo manejamos una patología infrecuente?</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">El carcinoma primario de uretra es un tumor de escasa incidencia, ocupa menos del 0,1% de las neoplasias genitourinarias. La mayoría de tumores corresponden a carcinomas escamosos, siendo mucho menos frecuentes los adenocarcinomas.</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">El tratamiento curativo es la cirugía y las técnicas dependen de la localización del tumor. La cirugía conservadora será de elección siempre que ésta no comprometa la curación. Determinadas localizaciones o extensión de enfermedad pueden requerir cirugía mutilante. En aquellos casos en los que no es posible un tratamiento quirúrgico se emplean otras estrategias terapéuticas (radioterapia o quimioterapia), sin que se disponga de estudios con número suficiente de pacientes que permitan establecer la mejor actitud terapéutica.</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Presentamos el caso de una mujer de 35 años afecta de adenocarcinoma parauretral avanzado al diagnóstico. Ante la imposibilidad de recibir tratamiento quirúrgico fue tratada con quimioterapia más radioterapia. El tratamiento combinado produjo respuesta completa pero posteriormente apareció una recaída precoz que condicionó el exitus.</p>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span class="elsevierStyleSectionTitle">Advanced urethral carcinoma. which is the best management of a infrequent disease?</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Urethral cancer is an uncommon tumor (0.1% of all genitourinary neoplasms). Most of them are squamous carcinoma, adenocarcinomas are about 5% of all urethral cancer.</p><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Surgery is the only curative treatment. Surgical technics depend of tumoral location and extension. Conservative surgery is elective if survival is not compromised. Extensive surgery is needed in large lessions. Chemotherapy (CT) and radiotherapy (RT) must be used in patients in wich surgery is not possible. Due to the low incidence of this neoplasm is not well established the best therapeutic approach.</p><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">We present the case of a female (35 years old) with a diagnosis of urethral adenocarcinoma. The initial stage was IV due to non-regional lymph nodes metastases. Surgery was impossible and the patient received chemotherapy and radiotherapy. The patient achieved complete response with CT but a progression was observed in course of RT. The patient died due to sistemic progression.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Referencias" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:20 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Female urethral cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "V. 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| año/Mes | Html | Total | |
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| 2024 Septiembre | 0 | 6 | 6 |
| 2024 Agosto | 0 | 7 | 7 |
| 2024 Junio | 0 | 3 | 3 |
| 2024 Mayo | 0 | 1 | 1 |
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| 2024 Marzo | 0 | 15 | 15 |
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| 2023 Octubre | 0 | 25 | 25 |
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| 2023 Agosto | 0 | 9 | 9 |
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| 2023 Junio | 0 | 5 | 5 |
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| 2023 Marzo | 3 | 10 | 13 |
| 2023 Febrero | 0 | 5 | 5 |
| 2022 Diciembre | 0 | 3 | 3 |
| 2022 Noviembre | 0 | 12 | 12 |
| 2022 Octubre | 0 | 5 | 5 |
| 2022 Septiembre | 0 | 10 | 10 |
| 2022 Agosto | 0 | 8 | 8 |
| 2022 Julio | 0 | 9 | 9 |
| 2022 Junio | 0 | 2 | 2 |
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| 2022 Marzo | 0 | 4 | 4 |
| 2021 Diciembre | 0 | 4 | 4 |
| 2021 Noviembre | 0 | 4 | 4 |
| 2021 Octubre | 0 | 2 | 2 |
| 2021 Junio | 0 | 1 | 1 |
| 2021 Mayo | 0 | 5 | 5 |
| 2021 Abril | 0 | 6 | 6 |
| 2021 Febrero | 0 | 1 | 1 |
| 2021 Enero | 0 | 7 | 7 |
| 2020 Diciembre | 0 | 3 | 3 |
| 2020 Noviembre | 0 | 1 | 1 |
| 2020 Octubre | 0 | 2 | 2 |
| 2020 Septiembre | 0 | 4 | 4 |
| 2020 Agosto | 0 | 2 | 2 |
| 2020 Julio | 0 | 2 | 2 |
| 2020 Junio | 0 | 4 | 4 |
| 2020 Mayo | 0 | 8 | 8 |
| 2020 Abril | 0 | 7 | 7 |
| 2020 Marzo | 0 | 3 | 3 |
| 2020 Febrero | 0 | 3 | 3 |
| 2020 Enero | 0 | 5 | 5 |
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| 2019 Noviembre | 0 | 3 | 3 |
| 2019 Octubre | 0 | 1 | 1 |
| 2019 Septiembre | 0 | 5 | 5 |
| 2019 Agosto | 0 | 1 | 1 |
| 2019 Julio | 0 | 10 | 10 |
| 2019 Junio | 0 | 11 | 11 |
| 2019 Mayo | 0 | 41 | 41 |
| 2019 Abril | 0 | 6 | 6 |
| 2019 Febrero | 0 | 2 | 2 |
| 2018 Diciembre | 0 | 4 | 4 |
| 2018 Febrero | 1 | 1 | 2 |
| 2018 Enero | 0 | 1 | 1 |
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| 2017 Noviembre | 2 | 5 | 7 |
| 2017 Octubre | 5 | 2 | 7 |
| 2017 Septiembre | 2 | 3 | 5 |
| 2017 Agosto | 5 | 2 | 7 |
| 2017 Julio | 4 | 1 | 5 |
| 2017 Junio | 4 | 1 | 5 |
| 2017 Mayo | 16 | 3 | 19 |
| 2017 Abril | 15 | 1 | 16 |
| 2017 Marzo | 13 | 30 | 43 |
| 2017 Febrero | 13 | 2 | 15 |
| 2017 Enero | 8 | 0 | 8 |
| 2016 Diciembre | 18 | 3 | 21 |
| 2016 Noviembre | 24 | 3 | 27 |
| 2016 Octubre | 28 | 5 | 33 |
| 2016 Septiembre | 20 | 5 | 25 |
| 2016 Agosto | 14 | 0 | 14 |
| 2016 Julio | 12 | 4 | 16 |
| 2016 Junio | 13 | 5 | 18 |
| 2016 Mayo | 14 | 8 | 22 |
| 2016 Abril | 12 | 6 | 18 |
| 2016 Marzo | 11 | 8 | 19 |
| 2016 Febrero | 10 | 8 | 18 |
| 2016 Enero | 10 | 8 | 18 |
| 2015 Diciembre | 12 | 7 | 19 |
| 2015 Noviembre | 15 | 3 | 18 |
| 2015 Octubre | 14 | 4 | 18 |
| 2015 Septiembre | 16 | 2 | 18 |
| 2015 Agosto | 12 | 5 | 17 |
| 2015 Julio | 12 | 4 | 16 |
| 2015 Junio | 7 | 1 | 8 |
| 2015 Mayo | 7 | 0 | 7 |
| 2015 Abril | 6 | 10 | 16 |
| 2015 Marzo | 4 | 3 | 7 |
| 2015 Febrero | 3 | 4 | 7 |
| 2015 Enero | 4 | 1 | 5 |
| 2014 Diciembre | 9 | 4 | 13 |
| 2014 Noviembre | 6 | 4 | 10 |
| 2014 Octubre | 14 | 2 | 16 |
| 2014 Septiembre | 13 | 1 | 14 |
| 2014 Agosto | 5 | 2 | 7 |
| 2014 Julio | 7 | 2 | 9 |
| 2014 Junio | 9 | 1 | 10 |
| 2014 Mayo | 4 | 2 | 6 |
| 2014 Abril | 6 | 2 | 8 |
| 2014 Marzo | 1 | 2 | 3 |
| 2014 Febrero | 4 | 0 | 4 |
| 2014 Enero | 6 | 2 | 8 |
| 2013 Diciembre | 7 | 4 | 11 |
| 2013 Noviembre | 11 | 2 | 13 |
| 2013 Octubre | 7 | 2 | 9 |
| 2013 Septiembre | 5 | 2 | 7 |
| 2013 Agosto | 4 | 2 | 6 |
| 2013 Julio | 3 | 0 | 3 |
| 2004 Enero | 269 | 0 | 269 |
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