Autoaumento vesical por laparoscopia. Modelo experimental en conejos (oryctolagus cuniculus)
Laparoscopic vesical autoaugmentation: An animal model in rabbits (oryctolagus cuniculus)
R.E. Sánchez-salas
, K.J. Palmer-román*, H. Dávila barrios*, A. Sánchez-ismayel**, R. Miquilarena***
,1
Autor para correspondencia
raersas@hotmail.com
Correspondencia autor: Dr. R.E. Sánchez-Salas Servicio de Urología. Hospital Universitario de Caracas. Universidad Central de Venezuela. Caracas, Venezuela. Tel.: 00 58 212 2658482
Correspondencia autor: Dr. R.E. Sánchez-Salas Servicio de Urología. Hospital Universitario de Caracas. Universidad Central de Venezuela. Caracas, Venezuela. Tel.: 00 58 212 2658482
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Tel.: 00 58 212 2658482" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Laparoscopic vesical autoaugmentation: An animal model in rabbits (<span class="elsevierStyleItalic">oryctolagus cuniculus</span>)" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2007-04-01" "fechaAceptado" => "2007-06-01" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec88670" "palabras" => array:3 [ 0 => "Laparoscopia" 1 => "Autoaumento vesical" 2 => "Modelo experimental" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec88669" "palabras" => array:3 [ 0 => "Laparoscopy" 1 => "Bladder autoaugmentation" 2 => "Experimental model" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span class="elsevierStyleSectionTitle">Introducción</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">La vejiga pequeña y contraída representa un cuadro clínico de difícil terapéutica y no siempre efectiva. Se presenta la cirugía preservadora de urotelio como una opción que permite el aumento de la capacidad vesical. Nuestro objetivo fue evaluar la factibilidad del conejo (Oryctolagus cuniculus) como modelo experimental de enseñanza, entrenamiento y aplicación de técnica para el autoaumento vesical por laparoscopia</p> <span class="elsevierStyleSectionTitle">Material y métodos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Cinco conejos (Oryctolagus cuniculus), machos, New Zealand, fueron intervenidos laparoscópicamente por técnica transperitoneal de tres puertos, realizándose autoaumento vesical mediante detrusorectomía. Se realizó cistometría simple preoperatoria y postoperatoria inmediata, mediata y tardía, para verificar modificaciones de capacidad vesical</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">5 conejos machos fueron operados en un tiempo promedio de 68,8 minutos (rango 44-120). Se realize medición de la capacidad vesical preoperatoria con promedio de 25.8cc (7-52) disminuyendo la postoperatoria inmediata en un 33%. Se verificó aumento de capacidad vesical postoperatoria de 72% y 52% para el séptimo y decimoquinto día, respectivamente. Estos porcentajes fueron estadísticamente significativos con 95% de confianza. Se presentaron 2 lesiones vesicales como complicación transoperatoria y un absceso como complicación postoperatoria</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">El modelo animal en conejos para la técnica de autoaumento vesical por laparoscopia es un modelo factible para enseñanza, entrenamiento y aplicación</p>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span class="elsevierStyleSectionTitle">Introduction</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Small contracted bladder remains a challenge in clinical urological practice and treatment options are not always effective. Urothelium sparing surgical techniques represent a reasonable therapeutical option. We aimed to evaluate the feasibility of a rabbit model (Oryctolagus cuniculus) in the teaching and training setting for laparoscopic vesical autoaugmentation</p> <span class="elsevierStyleSectionTitle">Methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Transperitoneal laparoscopic bladder autoaugmentation was performed in five New Zealand male rabbits (Oryctolagus cuniculus). A three port technique was used for all cases. Circumferential detrusorectomy was performed with vascular pedicles sparing, subsequently submucosal detailed blunt dissection allowed the creation of a bladder diverticulum which was verified intraoperatively. Eye-ball cystometry was performed preoperatively and postoperatively to verify bladder capacity variations. Postoperatively cystometry was done immediately after the procedure and 7 and 15 days postoperatively. Statistical analysis was performed with T-student model. A p-value < 0.05 was considered of significance for the analysis. Surgical procedure and perioperative animal care was minutely precised according to the Guidelines of the Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Five New Zealand male rabbits (Oryctolagus cuniculus) were surgically treated as described. Median operative time was 68.8 minutes (range 44 -120). Median preoperatory bladder capacity for the series was 25.8 cc (7-52). Median postoperative bladder capacity was diminished in 33% immediately after the operation. Then, bladder capacity augmented 72% and 52% for 7<span class="elsevierStyleSup">th</span> and 15<span class="elsevierStyleSup">th</span> postoperative days, respectively. Percentage variation in bladder capacity is statistically significant. Two operative complications (mucosal tear) were reported. A postoperatory abscess was observed in one animal</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">The rabbit (Oryctolagus cuniculus) model for the laparoscopic bladder autoaugmentation is feasible for teaching, training and research. Bigger series and longer follow-up should be addressed</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Referencias" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:16 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Laparoscopic retropubic auto-augmentation of the bladder" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "E. McDougall" 1 => "R. Clayman" 2 => "R. Figenshau" 3 => "M. 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| año/Mes | Html | Total | |
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| 2024 Octubre | 0 | 9 | 9 |
| 2024 Septiembre | 0 | 19 | 19 |
| 2024 Agosto | 0 | 12 | 12 |
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| 2024 Marzo | 0 | 26 | 26 |
| 2024 Febrero | 0 | 4 | 4 |
| 2024 Enero | 0 | 6 | 6 |
| 2023 Diciembre | 0 | 8 | 8 |
| 2023 Noviembre | 0 | 23 | 23 |
| 2023 Octubre | 0 | 30 | 30 |
| 2023 Septiembre | 0 | 22 | 22 |
| 2023 Agosto | 0 | 2 | 2 |
| 2023 Julio | 0 | 25 | 25 |
| 2023 Junio | 0 | 7 | 7 |
| 2023 Mayo | 0 | 2 | 2 |
| 2023 Marzo | 1 | 3 | 4 |
| 2023 Febrero | 0 | 5 | 5 |
| 2023 Enero | 0 | 4 | 4 |
| 2022 Diciembre | 0 | 6 | 6 |
| 2022 Noviembre | 0 | 13 | 13 |
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| 2022 Septiembre | 0 | 8 | 8 |
| 2022 Agosto | 0 | 9 | 9 |
| 2022 Julio | 0 | 1 | 1 |
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| 2022 Marzo | 0 | 5 | 5 |
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| 2022 Enero | 0 | 4 | 4 |
| 2021 Diciembre | 0 | 1 | 1 |
| 2021 Noviembre | 0 | 2 | 2 |
| 2021 Octubre | 0 | 2 | 2 |
| 2021 Septiembre | 0 | 2 | 2 |
| 2021 Agosto | 0 | 5 | 5 |
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| 2021 Junio | 0 | 2 | 2 |
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| 2020 Agosto | 0 | 9 | 9 |
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| 2020 Mayo | 0 | 4 | 4 |
| 2020 Abril | 0 | 1 | 1 |
| 2020 Marzo | 0 | 6 | 6 |
| 2020 Febrero | 0 | 5 | 5 |
| 2020 Enero | 0 | 8 | 8 |
| 2019 Diciembre | 0 | 16 | 16 |
| 2019 Noviembre | 0 | 10 | 10 |
| 2019 Octubre | 0 | 5 | 5 |
| 2019 Septiembre | 0 | 10 | 10 |
| 2019 Agosto | 0 | 3 | 3 |
| 2019 Julio | 0 | 11 | 11 |
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| 2019 Mayo | 0 | 51 | 51 |
| 2019 Abril | 0 | 23 | 23 |
| 2019 Marzo | 0 | 11 | 11 |
| 2019 Febrero | 0 | 12 | 12 |
| 2019 Enero | 0 | 2 | 2 |
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| 2018 Octubre | 0 | 10 | 10 |
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| 2018 Enero | 6 | 3 | 9 |
| 2017 Noviembre | 5 | 5 | 10 |
| 2017 Octubre | 2 | 4 | 6 |
| 2017 Septiembre | 3 | 3 | 6 |
| 2017 Agosto | 5 | 0 | 5 |
| 2017 Julio | 2 | 7 | 9 |
| 2017 Junio | 15 | 6 | 21 |
| 2017 Mayo | 8 | 4 | 12 |
| 2017 Abril | 4 | 4 | 8 |
| 2017 Marzo | 8 | 31 | 39 |
| 2017 Febrero | 10 | 4 | 14 |
| 2017 Enero | 6 | 2 | 8 |
| 2016 Diciembre | 13 | 6 | 19 |
| 2016 Noviembre | 23 | 1 | 24 |
| 2016 Octubre | 43 | 8 | 51 |
| 2016 Septiembre | 22 | 3 | 25 |
| 2016 Agosto | 13 | 5 | 18 |
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| 2016 Junio | 13 | 8 | 21 |
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| 2016 Abril | 5 | 9 | 14 |
| 2016 Marzo | 8 | 7 | 15 |
| 2016 Febrero | 5 | 7 | 12 |
| 2016 Enero | 6 | 8 | 14 |
| 2015 Diciembre | 7 | 15 | 22 |
| 2015 Noviembre | 16 | 3 | 19 |
| 2015 Octubre | 20 | 9 | 29 |
| 2015 Septiembre | 12 | 1 | 13 |
| 2015 Agosto | 9 | 2 | 11 |
| 2015 Julio | 8 | 4 | 12 |
| 2015 Junio | 2 | 0 | 2 |
| 2015 Mayo | 15 | 1 | 16 |
| 2015 Abril | 11 | 6 | 17 |
| 2015 Marzo | 5 | 2 | 7 |
| 2015 Febrero | 4 | 0 | 4 |
| 2015 Enero | 7 | 1 | 8 |
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| 2014 Noviembre | 6 | 2 | 8 |
| 2014 Octubre | 24 | 1 | 25 |
| 2014 Septiembre | 14 | 0 | 14 |
| 2014 Agosto | 6 | 1 | 7 |
| 2014 Julio | 16 | 3 | 19 |
| 2014 Junio | 7 | 2 | 9 |
| 2014 Mayo | 5 | 2 | 7 |
| 2014 Abril | 6 | 3 | 9 |
| 2014 Marzo | 9 | 1 | 10 |
| 2014 Febrero | 5 | 3 | 8 |
| 2014 Enero | 6 | 1 | 7 |
| 2013 Diciembre | 9 | 3 | 12 |
| 2013 Noviembre | 7 | 6 | 13 |
| 2013 Octubre | 4 | 10 | 14 |
| 2013 Septiembre | 6 | 5 | 11 |
| 2013 Agosto | 3 | 14 | 17 |
| 2013 Julio | 3 | 2 | 5 |
| 2008 Junio | 236 | 0 | 236 |
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