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La integración de la cirugía y el tratamiento quimioterápico en el cáncer de vejiga infiltrante
Comprehensive surgical and chemotherapy treatment for invasive bladder cancer
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Duque Ruiz, John Watson, Eugenio Rocha, Eric Barret, Xavier Cathelineau, Francois Rozet, Marc Galiano, Guy Vallancien" "autores" => array:9 [ 0 => array:3 [ "nombre" => "Rafael" "apellidos" => "Sánchez-Salas" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 1 => array:3 [ "nombre" => "Gemma I." "apellidos" => "Duque Ruiz" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] 2 => array:3 [ "nombre" => "John" "apellidos" => "Watson" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 3 => array:3 [ "nombre" => "Eugenio" "apellidos" => "Rocha" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 4 => array:3 [ "nombre" => "Eric" "apellidos" => "Barret" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 5 => array:3 [ "nombre" => "Xavier" "apellidos" => "Cathelineau" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 6 => array:3 [ "nombre" => "Francois" "apellidos" => "Rozet" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 7 => array:3 [ "nombre" => "Marc" "apellidos" => "Galiano" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 8 => array:4 [ "nombre" => "Guy" "apellidos" => "Vallancien" "email" => array:1 [ 0 => "guy.vallancien@imm.fr" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor1" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Departamento de Urología, Institut Montsouris, Université Paris Descartes, París, Francia" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Servicio de Urología, Hospital Universitario 12 Octubre, Madrid, España" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "⁎" "correspondencia" => "Autor para correspondencia." ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Comprehensive surgical and chemotherapy treatment for invasive bladder cancer" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2009-06-26" "fechaAceptado" => "2009-09-14" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec89490" "palabras" => array:3 [ 0 => "Cáncer de vejiga infiltrante" 1 => "Quimioterapia perioperatoria" 2 => "Cistectomía radical" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec89489" "palabras" => array:3 [ 0 => "Invasive bladder cancer" 1 => "Perioperative chemotherapy" 2 => "Radical cystectomy" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span class="elsevierStyleSectionTitle">Introducción</span><p class="elsevierStyleSimplePara elsevierViewall">El tratamiento del cáncer vesical de células transicionales con invasión muscular sigue siendo difícil, debido a los múltiples patrones de comportamiento biológico que muestra esta enfermedad. Hay controversia en cuanto a la aplicación de tratamiento sistémico en el carcinoma vesical infiltrante y el momento ideal de la indicación de la quimioterapia perioperatoria. Se presenta una visión general de la terapia sistémica en cáncer vesical infiltrante.</p> <span class="elsevierStyleSectionTitle">Material y métodos</span><p class="elsevierStyleSimplePara elsevierViewall">Realizamos una búsqueda informática en PubMed limitando la información a los últimos 5 años y seleccionamos artículos en inglés y en español referentes a “chemotherapy in bladder cancer”. Se seleccionaron estudios aleatorizados, metaanálisis y ensayos clínicos.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Obtuvimos 241 artículos. Un total de 31 artículos fueron referentes a quimioterapia neoadyuvante y adyuvante en el carcinoma vesical infiltrante. Agrupamos los artículos en tres grupos según su referencia a neoadyuvancia, adyuvancia o neoadyuvancia y adyuvancia de forma conjunta. Dicha información se encuentra reflejada en las tablas anexas al manuscrito.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">El abordaje multidisciplinario en el tratamiento del carcinoma vesical infiltrante es indispensable para garantizar un adecuado control oncológico. La evaluación detallada y la selección adecuada del paciente son la herramienta fundamental para determinar el mejor momento para indicar la quimioterapia.</p>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span class="elsevierStyleSectionTitle">Introduction</span><p class="elsevierStyleSimplePara elsevierViewall">Treating patients with invasive transitional cell carcinoma of the bladder remains difficult due to the multiple biological behaviour patterns found in this disease. There is still controversy regarding the use of systemic treatment in invasive bladder carcinoma and the ideal moment for launching perioperative chemotherapy. We present an overview of current trends for systemic treatment of invasive bladder carcinoma.</p> <span class="elsevierStyleSectionTitle">Material and methods</span><p class="elsevierStyleSimplePara elsevierViewall">Using MEDLINE, we reviewed relevant English and Spanish language literature published during the last five years, with “chemotherapy in bladder cancer” as keywords. We selected randomized trials, meta-analyses and clinical trials.</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">We obtained a total of 241 articles. Thirty-one of them referred to neoadjuvant and adjuvant chemotherapy in invasive bladder cancer. We classified the articles in three different groups neoadjuvant, adjuvant and neoadjuvant plus chemotherapy. All of that information is displayed in the tables within the text.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">A multidisciplinary approach to the treatment of invasive bladder cancer is essential to guarantee adequate oncological control. A detailed evaluation and proper selection of each patient is fundamental in determining the best moment to start chemotherapy.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:24 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Defining optimal therapy for muscle invasive bladder cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "H.W. Herr" 1 => "Z. Dotan" 2 => "M. 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| año/Mes | Html | Total | |
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| 2024 Octubre | 0 | 3 | 3 |
| 2024 Septiembre | 0 | 1 | 1 |
| 2024 Agosto | 0 | 4 | 4 |
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| 2024 Enero | 0 | 15 | 15 |
| 2023 Diciembre | 0 | 17 | 17 |
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| 2023 Octubre | 0 | 45 | 45 |
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| 2023 Mayo | 0 | 7 | 7 |
| 2023 Abril | 0 | 5 | 5 |
| 2023 Marzo | 1 | 3 | 4 |
| 2023 Febrero | 0 | 9 | 9 |
| 2023 Enero | 0 | 9 | 9 |
| 2022 Diciembre | 0 | 6 | 6 |
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| 2022 Septiembre | 0 | 24 | 24 |
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| 2022 Febrero | 0 | 2 | 2 |
| 2022 Enero | 0 | 2 | 2 |
| 2021 Diciembre | 0 | 4 | 4 |
| 2021 Noviembre | 0 | 5 | 5 |
| 2021 Octubre | 0 | 7 | 7 |
| 2021 Septiembre | 0 | 1 | 1 |
| 2021 Agosto | 0 | 5 | 5 |
| 2021 Julio | 0 | 4 | 4 |
| 2021 Junio | 0 | 1 | 1 |
| 2021 Mayo | 0 | 4 | 4 |
| 2021 Abril | 0 | 2 | 2 |
| 2021 Marzo | 0 | 3 | 3 |
| 2021 Febrero | 0 | 4 | 4 |
| 2021 Enero | 0 | 3 | 3 |
| 2020 Diciembre | 0 | 6 | 6 |
| 2020 Noviembre | 0 | 4 | 4 |
| 2020 Octubre | 0 | 5 | 5 |
| 2020 Septiembre | 0 | 4 | 4 |
| 2020 Agosto | 0 | 11 | 11 |
| 2020 Julio | 0 | 4 | 4 |
| 2020 Junio | 0 | 7 | 7 |
| 2020 Mayo | 0 | 8 | 8 |
| 2020 Abril | 0 | 4 | 4 |
| 2020 Marzo | 0 | 9 | 9 |
| 2020 Febrero | 0 | 11 | 11 |
| 2020 Enero | 0 | 11 | 11 |
| 2019 Diciembre | 0 | 7 | 7 |
| 2019 Noviembre | 0 | 5 | 5 |
| 2019 Octubre | 0 | 12 | 12 |
| 2019 Septiembre | 0 | 6 | 6 |
| 2019 Agosto | 0 | 11 | 11 |
| 2019 Julio | 0 | 28 | 28 |
| 2019 Junio | 0 | 24 | 24 |
| 2019 Mayo | 0 | 54 | 54 |
| 2019 Abril | 0 | 25 | 25 |
| 2019 Marzo | 0 | 7 | 7 |
| 2019 Febrero | 0 | 11 | 11 |
| 2019 Enero | 0 | 1 | 1 |
| 2018 Diciembre | 0 | 10 | 10 |
| 2018 Noviembre | 0 | 9 | 9 |
| 2018 Octubre | 0 | 21 | 21 |
| 2018 Agosto | 0 | 2 | 2 |
| 2018 Julio | 0 | 2 | 2 |
| 2018 Febrero | 1 | 2 | 3 |
| 2017 Diciembre | 0 | 2 | 2 |
| 2017 Noviembre | 3 | 2 | 5 |
| 2017 Octubre | 2 | 5 | 7 |
| 2017 Septiembre | 2 | 4 | 6 |
| 2017 Agosto | 3 | 7 | 10 |
| 2017 Julio | 2 | 13 | 15 |
| 2017 Junio | 5 | 7 | 12 |
| 2017 Mayo | 10 | 6 | 16 |
| 2017 Abril | 11 | 20 | 31 |
| 2017 Marzo | 15 | 13 | 28 |
| 2017 Febrero | 5 | 3 | 8 |
| 2017 Enero | 2 | 0 | 2 |
| 2016 Diciembre | 4 | 12 | 16 |
| 2016 Noviembre | 16 | 11 | 27 |
| 2016 Octubre | 26 | 25 | 51 |
| 2016 Septiembre | 13 | 3 | 16 |
| 2016 Agosto | 10 | 10 | 20 |
| 2016 Julio | 14 | 7 | 21 |
| 2016 Junio | 32 | 26 | 58 |
| 2016 Mayo | 30 | 25 | 55 |
| 2016 Abril | 31 | 30 | 61 |
| 2016 Marzo | 29 | 16 | 45 |
| 2016 Febrero | 23 | 14 | 37 |
| 2016 Enero | 17 | 17 | 34 |
| 2015 Diciembre | 25 | 21 | 46 |
| 2015 Noviembre | 27 | 17 | 44 |
| 2015 Octubre | 32 | 18 | 50 |
| 2015 Septiembre | 26 | 11 | 37 |
| 2015 Agosto | 19 | 6 | 25 |
| 2015 Julio | 14 | 7 | 21 |
| 2015 Junio | 14 | 6 | 20 |
| 2015 Mayo | 19 | 11 | 30 |
| 2015 Abril | 25 | 18 | 43 |
| 2015 Marzo | 26 | 16 | 42 |
| 2015 Febrero | 28 | 17 | 45 |
| 2015 Enero | 29 | 7 | 36 |
| 2014 Diciembre | 36 | 14 | 50 |
| 2014 Noviembre | 23 | 6 | 29 |
| 2014 Octubre | 35 | 8 | 43 |
| 2014 Septiembre | 29 | 1 | 30 |
| 2014 Agosto | 26 | 2 | 28 |
| 2014 Julio | 28 | 2 | 30 |
| 2014 Junio | 31 | 2 | 33 |
| 2014 Mayo | 20 | 3 | 23 |
| 2014 Abril | 18 | 3 | 21 |
| 2014 Marzo | 20 | 2 | 22 |
| 2014 Febrero | 21 | 5 | 26 |
| 2014 Enero | 22 | 1 | 23 |
| 2013 Diciembre | 35 | 4 | 39 |
| 2013 Noviembre | 26 | 5 | 31 |
| 2013 Octubre | 20 | 10 | 30 |
| 2013 Septiembre | 15 | 7 | 22 |
| 2013 Agosto | 15 | 6 | 21 |
| 2013 Julio | 7 | 3 | 10 |
| 2009 Noviembre | 1687 | 0 | 1687 |
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