Carcinoma urotelial de vejiga tipo nested. una variante histológica poco frecuente
Nested variant of urothelial carcinoma. a rare histological variant
Joaquín Marti mestrea,1
, Daniel Cañis sáncheza, El Boutaibi abdelmounina, Mario E. Mendoza cárcamoa, Jorge Delagneau ribasa, Joaquín Jaén martínez*
Autor para correspondencia
jmmestre@terra.es
Correspondencia autor: Dr. Joaquín Martí Mestre Servicio de Urología. Hospital de Tortosa Verge de la Cinta Esplanetes, s/n - 43500 Tortosa (Tarragona). Tel.: 977 519 100
Correspondencia autor: Dr. Joaquín Martí Mestre Servicio de Urología. Hospital de Tortosa Verge de la Cinta Esplanetes, s/n - 43500 Tortosa (Tarragona). Tel.: 977 519 100
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Tarragona" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "1" "correspondencia" => "Correspondencia autor: Dr. Joaquín Martí Mestre Servicio de Urología. Hospital de Tortosa Verge de la Cinta Esplanetes, s/n - 43500 Tortosa (Tarragona). Tel.: 977 519 100" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Nested variant of urothelial carcinoma. a rare histological variant" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2007-04-01" "fechaAceptado" => "2007-06-01" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec88798" "palabras" => array:3 [ 0 => "Carcinoma de vejiga" 1 => "Carcinoma urotelial" 2 => "Nested carcinoma" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec88797" "palabras" => array:3 [ 0 => "Bladder carcinoma" 1 => "Urothelial carcinoma" 2 => "Nested variant" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">El carcinoma urotelial de vejiga tipo “nested” o en nidos es una variante histológica rara dentro de los tumores uroteliales de vejiga. Aunque las manifestaciones clínicas son semejantes a los demás tumores de vejiga, su apariencia macroscópica puede ser inexpresiva, con crecimiento submucoso difícil de detectar en la cistoscopia, lo que puede retrasar el diagnóstico. Microscópicamente se caracteriza por la distribución celular en forma de nidos y túbulos. Presentan un bajo grado de atipia citológico que simula un carcinoma urotelial de bajo grado, lo que contrasta con un patrón de crecimiento ampliamente infiltrativo que le confiere un mal pronóstico a pesar de tratamientos radicales.</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Presentamos el caso de un paciente afecto de un carcinoma urotelial de vejiga tipo nested sometido a cistoprostatectomia radical y tratamiento con quimioterapia adyuvante que se encuentra libre de enfermedad un año después del diagnóstico.</p>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">The nested variant of urothelial carcinoma is a rare histological tumor of urinary bladder. The clinical symptoms are similar to those of the classic urothelial carcinomas. Its macroscopic appearance can be very subtle due to its preference for a submucosal growth leading to a possible delay in diagnosis. Microscopically, it is characterized by nests and tubules formation. While the neoplastic cells exhibit low-grade histological features, the growth pattern is widely infiltrative conferring this neoplasia a bad prognosis even if a radical treatment is performed.</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">We present a case of a patient affected by a nested variant of urothelial carcinoma of urinary bladder to whom a radical cystoprostatectomy was performed and adjuvant chemotherapy was given. He is alive and free of disease one year after the diagnosis.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Referencias" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:11 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." 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| 2022 Junio | 0 | 4 | 4 |
| 2022 Mayo | 0 | 4 | 4 |
| 2022 Abril | 0 | 9 | 9 |
| 2022 Marzo | 0 | 5 | 5 |
| 2022 Febrero | 0 | 2 | 2 |
| 2022 Enero | 0 | 2 | 2 |
| 2021 Diciembre | 0 | 8 | 8 |
| 2021 Noviembre | 0 | 2 | 2 |
| 2021 Octubre | 0 | 2 | 2 |
| 2021 Agosto | 0 | 2 | 2 |
| 2021 Julio | 0 | 1 | 1 |
| 2021 Junio | 0 | 7 | 7 |
| 2021 Mayo | 0 | 7 | 7 |
| 2021 Abril | 0 | 1 | 1 |
| 2021 Marzo | 0 | 7 | 7 |
| 2021 Febrero | 0 | 2 | 2 |
| 2021 Enero | 0 | 1 | 1 |
| 2020 Diciembre | 0 | 1 | 1 |
| 2020 Noviembre | 0 | 1 | 1 |
| 2020 Octubre | 0 | 3 | 3 |
| 2020 Septiembre | 0 | 3 | 3 |
| 2020 Agosto | 0 | 10 | 10 |
| 2020 Julio | 0 | 7 | 7 |
| 2020 Junio | 0 | 2 | 2 |
| 2020 Mayo | 0 | 5 | 5 |
| 2020 Abril | 0 | 2 | 2 |
| 2020 Marzo | 0 | 16 | 16 |
| 2020 Febrero | 0 | 4 | 4 |
| 2020 Enero | 0 | 20 | 20 |
| 2019 Diciembre | 0 | 28 | 28 |
| 2019 Noviembre | 0 | 14 | 14 |
| 2019 Octubre | 0 | 15 | 15 |
| 2019 Septiembre | 0 | 19 | 19 |
| 2019 Agosto | 0 | 11 | 11 |
| 2019 Julio | 0 | 35 | 35 |
| 2019 Junio | 0 | 19 | 19 |
| 2019 Mayo | 0 | 64 | 64 |
| 2019 Abril | 0 | 43 | 43 |
| 2019 Marzo | 0 | 9 | 9 |
| 2019 Febrero | 0 | 22 | 22 |
| 2019 Enero | 0 | 7 | 7 |
| 2018 Diciembre | 0 | 20 | 20 |
| 2018 Noviembre | 0 | 15 | 15 |
| 2018 Octubre | 0 | 27 | 27 |
| 2018 Julio | 0 | 1 | 1 |
| 2018 Junio | 0 | 2 | 2 |
| 2018 Mayo | 0 | 1 | 1 |
| 2018 Marzo | 2 | 0 | 2 |
| 2018 Febrero | 8 | 1 | 9 |
| 2018 Enero | 4 | 2 | 6 |
| 2017 Diciembre | 7 | 5 | 12 |
| 2017 Noviembre | 7 | 12 | 19 |
| 2017 Octubre | 5 | 4 | 9 |
| 2017 Septiembre | 4 | 8 | 12 |
| 2017 Agosto | 5 | 8 | 13 |
| 2017 Julio | 7 | 4 | 11 |
| 2017 Junio | 11 | 21 | 32 |
| 2017 Mayo | 28 | 11 | 39 |
| 2017 Abril | 3 | 2 | 5 |
| 2017 Marzo | 6 | 16 | 22 |
| 2017 Febrero | 18 | 8 | 26 |
| 2017 Enero | 7 | 7 | 14 |
| 2016 Diciembre | 15 | 20 | 35 |
| 2016 Noviembre | 32 | 18 | 50 |
| 2016 Octubre | 33 | 16 | 49 |
| 2016 Septiembre | 26 | 10 | 36 |
| 2016 Agosto | 18 | 5 | 23 |
| 2016 Julio | 17 | 3 | 20 |
| 2016 Junio | 22 | 18 | 40 |
| 2016 Mayo | 26 | 27 | 53 |
| 2016 Abril | 16 | 20 | 36 |
| 2016 Marzo | 16 | 16 | 32 |
| 2016 Febrero | 17 | 15 | 32 |
| 2016 Enero | 14 | 27 | 41 |
| 2015 Diciembre | 16 | 11 | 27 |
| 2015 Noviembre | 22 | 7 | 29 |
| 2015 Octubre | 28 | 6 | 34 |
| 2015 Septiembre | 19 | 7 | 26 |
| 2015 Agosto | 15 | 8 | 23 |
| 2015 Julio | 17 | 3 | 20 |
| 2015 Junio | 9 | 3 | 12 |
| 2015 Mayo | 14 | 3 | 17 |
| 2015 Abril | 16 | 12 | 28 |
| 2015 Marzo | 5 | 4 | 9 |
| 2015 Febrero | 12 | 1 | 13 |
| 2015 Enero | 11 | 9 | 20 |
| 2014 Diciembre | 12 | 5 | 17 |
| 2014 Noviembre | 14 | 1 | 15 |
| 2014 Octubre | 28 | 5 | 33 |
| 2014 Septiembre | 17 | 3 | 20 |
| 2014 Agosto | 20 | 10 | 30 |
| 2014 Julio | 17 | 3 | 20 |
| 2014 Junio | 27 | 8 | 35 |
| 2014 Mayo | 18 | 3 | 21 |
| 2014 Abril | 15 | 4 | 19 |
| 2014 Marzo | 19 | 5 | 24 |
| 2014 Febrero | 16 | 5 | 21 |
| 2014 Enero | 14 | 3 | 17 |
| 2013 Diciembre | 19 | 3 | 22 |
| 2013 Noviembre | 14 | 7 | 21 |
| 2013 Octubre | 14 | 36 | 50 |
| 2013 Septiembre | 8 | 10 | 18 |
| 2013 Agosto | 8 | 8 | 16 |
| 2013 Julio | 9 | 0 | 9 |
| 2009 Enero | 372 | 0 | 372 |
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