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Riñones parejos en trasplante
Paired kidneys in transplant
C. Juan1
Autor para correspondencia
jcregue0@ono.com

Correspondencia autor: Dr. Juan C. Regueiro López Servicio de Urología Hospital Regional Universitario Reina Sofía Avda. Menéndez Pidal, 1 - 14004 Córdoba Tel.: 957 010 001
, Regueiro. López, Manuel. Leva Vallejo, Rafael. Prieto Castro, Francisco. Anglada Curado, Francisco. Vela Jiménez, Mª. José Requena Tapia
Servicio de Urología. Hospital Regional Universitario Reina Sofía.Córdoba, España
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivos</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Muchos factores afectan la supervivencia del injerto y paciente en el resultado de un trasplante renal&#46; Estos factores dependen tanto del receptor como del donante&#46; Realizamos un estudio intentando obviar factores que dependen del donante&#46; Revisamos los ri&#241;ones parejas provenientes de un mismo donante cad&#225;ver&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Analizamos los factores de riesgo en la evoluci&#243;n y seguimiento de 556 trasplantes renales que corresponden a 278 parejas de ri&#241;ones&#46; Describimos sus diferencias&#44; su significaci&#243;n&#44; la supervivencia de injerto y paciente&#44; su funcionalidad a 3 y 5 a&#241;os y los factores de riesgo implicados en su funci&#243;n&#46; Se estudian variables inmunol&#243;gicas y no inmunol&#243;gicas intentando explicar los resultados inferiores en los injertos que se implantan en segundo lugar&#46; Se reagrupan los ri&#241;ones parejos en aquellos que no mostraron funci&#243;n pareja inicial dentro de la misma pareja&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Los resultados arrojan un discreto empeoramiento en la supervivencia de injerto y paciente para el grupo de segundo implante&#44; cifras superiores de creatinina&#44; sin obtener significaci&#243;n estad&#237;stica&#46; El estudio por regresi&#243;n de Cox solo establece como factores de riesgo el rechazo precoz &#40;inferior a tres meses&#41; y la tasa de incompatibilidad DR&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Este modelo de ri&#241;ones parejos podr&#237;a acercarnos de forma m&#225;s adecuada al an&#225;lisis de los factores de riesgo en trasplante de donante cad&#225;ver&#44; si m&#225;s pacientes se analizan de la misma forma&#46; Los ri&#241;ones parejas provenientes del mismo donante no muestran igual funci&#243;n a pesar de compartir las mismas condiciones del donante y del manejo peroperatorio&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objectives</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Many factors affect the graft and patient survival on the renal transplant outcome&#46; These factors depend so much of the recipient and donor&#46; We accomplished a study trying to circumvent factors that depend on the donor&#46; We checked the paired kidneys originating of a same donor cadaver&#46;</p> <span class="elsevierStyleSectionTitle">Patients and method</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">We examined the risk factors in the evolution and follow-up in 278 couples of kidney transplant&#46; We describe their differences&#44; significance&#44; the graft and patient survival&#44; their functionality in 3 and 5 years and the risk factors implicated in their function&#46; We study immunogenic and no immunogenic variables&#44; trying to explain the inferior results in the grafts that are established secondly&#46; We regroup the paired kidneys in those that they did not show paired initial function within the same couple&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">The results yield a discreet deterioration in the graft and patient survival for second group establish&#44; superior creatinina concentration&#44; without obtaining statistical significance&#46; The Cox regression study establishes the early rejection &#40;inferior to three months&#41; and DR incompatibility values like risk factors&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">This model of paired kidneys would be able to get close to best-suited form for risk factors analysis in kidney transplant from cadaver donors&#44; if more patients examine themselves in the same way&#46; The paired kidneys originating from the same donor do not show the same function in spite of sharing the same conditions of the donor and perioperative management&#46;</p>"
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ISSN: 02104806
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