Cistitis eosinofílica: Revisión y reporte de dos casos
Eosinophilic cystitis: review and two cases report
Luis F. Ebel Sepulveda
, A. Foneron**, L. Troncoso*, R. Cañoles*, C. Carrasco**, A. Hornig*, G. Gil*, D. Corti*
,1
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luisebel@uach.cl
Correspondencia autor: Dr. Luis F. Ebel Sepulveda Servicio de Urología. Hospital Regional de Valdivia Departamento de Urología. Universidad de Chile
Correspondencia autor: Dr. Luis F. Ebel Sepulveda Servicio de Urología. Hospital Regional de Valdivia Departamento de Urología. Universidad de Chile
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Ebel Sepulveda, A. Foneron, L. Troncoso, R. Cañoles, C. Carrasco, A. Hornig, G. Gil, D. Corti" "autores" => array:8 [ 0 => array:4 [ "nombre" => "Luis F." "apellidos" => "Ebel Sepulveda" "email" => array:1 [ 0 => "luisebel@uach.cl" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "*" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "A." "apellidos" => "Foneron" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">**</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "L." "apellidos" => "Troncoso" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "*" "identificador" => "aff0005" ] ] ] 3 => array:3 [ "nombre" => "R." "apellidos" => "Cañoles" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "*" "identificador" => "aff0005" ] ] ] 4 => array:3 [ "nombre" => "C." "apellidos" => "Carrasco" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">**</span>" "identificador" => "aff0010" ] ] ] 5 => array:3 [ "nombre" => "A." "apellidos" => "Hornig" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "*" "identificador" => "aff0005" ] ] ] 6 => array:3 [ "nombre" => "G." "apellidos" => "Gil" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "*" "identificador" => "aff0005" ] ] ] 7 => array:3 [ "nombre" => "D." "apellidos" => "Corti" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "*" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Urología - Hospital Regional de Valdivia y Departamento de Urología - Universidad Austral de Chile" "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Anatomía Patológica - Hospital Regional de Valdivia. Universidad Austral de Chile Chile" "etiqueta" => "<span class="elsevierStyleSup">**</span>" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "1" "correspondencia" => "Correspondencia autor: Dr. Luis F. Ebel Sepulveda Servicio de Urología. Hospital Regional de Valdivia Departamento de Urología. Universidad de Chile" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Eosinophilic cystitis: review and two cases report" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2007-07-01" "fechaAceptado" => "2007-08-01" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec88930" "palabras" => array:4 [ 0 => "Cistitis" 1 => "Cistitis eosinofílica" 2 => "Eosinofilia" 3 => "Vejiga" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec88929" "palabras" => array:4 [ 0 => "Cystitis" 1 => "Eosinophilic cystitis" 2 => "Eosinophilia" 3 => "Bladder" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">La cistitis eosinofílica es una enfermedad de baja frecuencia, con menos de 200 casos reportados en el mundo. Se caracteriza por la inflamación de toda la pared vesical, predominantemente por eosinófilos, con fibrosis y áreas de necrosis muscular. Su origen parece ser inmunológico aunque los desencadenantes no se conocen bien. Se han descrito varios factores predisponentes como enfermedades alérgicas, trauma vesical, fármacos, infecciones, etc. Afecta a pacientes de todas las edades, preferentemente adultos. Se presenta con polaquiuria, hematuria y dolor suprapúbico. Otros de menor frecuencia son disuria, retención urinaria, nicturia y enuresis. El estudio de laboratorio (sedimento de orina, urocultivo, hemograma) y radiológico (ecotomografía, pielografía de eliminación, tomomografía computada y resonancia nuclear magnética) son inespecíficos. En la cistoscopía se observan lesiones que pueden simular otras enfermedades, por lo que el diagnóstico definitivo es histológico. El manejo puede ser expectante o con antihistamínicos, antiinflamatorios y corticoides. En los casos refractarios al tratamiento médico la cirugía puede ser una alternativa. Reportamos dos casos de pacientes hombres, adultos, con su cuadro de presentación, estudio y manejo.</p>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Eosinophilic cystitis is a low frequency disease, with less than 200 reported cases in the world. It is characterized by a bladder wall inflammation, mainly by eosinophils, with fibrosis and muscle necrosis areas. Its origin seems to be immunological, although the triggers are not well known. Several predispose factor have been described such as allergic diseases, bladder injuries, drugs, infections, etc. It affects patient of all ages, mainly adults. It presents with frecuency, haematuria and suprapubic pain. Other less frequent symptoms are disuria, urinary retention, nicturia, and enuresis. The laboratory study (urinalysis, urinalysis and haemogram) and radiology (ultrasound, intravenous pyelography, computed tomography and nuclear magnetic resonance) are non specific. The lesions observed in the cystoscopy could emulate other diseases, that why the proper diagnostic is the histological analysis. The management could be observation o antihistaminic, anti-inflammatory and corticoid treatment. In refractory cases, surgery is an alternative. In this work, two male adult cases are reported with their symptoms, studies and management.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Referencias" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:38 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." 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| 2020 Noviembre | 0 | 5 | 5 |
| 2020 Octubre | 0 | 5 | 5 |
| 2020 Septiembre | 0 | 8 | 8 |
| 2020 Agosto | 0 | 9 | 9 |
| 2020 Julio | 0 | 9 | 9 |
| 2020 Junio | 0 | 4 | 4 |
| 2020 Mayo | 0 | 7 | 7 |
| 2020 Abril | 0 | 4 | 4 |
| 2020 Marzo | 0 | 4 | 4 |
| 2020 Febrero | 0 | 3 | 3 |
| 2020 Enero | 0 | 11 | 11 |
| 2019 Diciembre | 0 | 28 | 28 |
| 2019 Noviembre | 0 | 12 | 12 |
| 2019 Octubre | 0 | 2 | 2 |
| 2019 Septiembre | 0 | 6 | 6 |
| 2019 Agosto | 0 | 10 | 10 |
| 2019 Julio | 0 | 10 | 10 |
| 2019 Junio | 0 | 17 | 17 |
| 2019 Mayo | 0 | 57 | 57 |
| 2019 Abril | 0 | 32 | 32 |
| 2019 Marzo | 0 | 10 | 10 |
| 2019 Febrero | 0 | 16 | 16 |
| 2019 Enero | 0 | 6 | 6 |
| 2018 Diciembre | 0 | 10 | 10 |
| 2018 Noviembre | 0 | 16 | 16 |
| 2018 Octubre | 0 | 23 | 23 |
| 2018 Septiembre | 0 | 2 | 2 |
| 2018 Agosto | 0 | 2 | 2 |
| 2018 Mayo | 0 | 1 | 1 |
| 2018 Febrero | 2 | 1 | 3 |
| 2018 Enero | 4 | 5 | 9 |
| 2017 Diciembre | 5 | 7 | 12 |
| 2017 Noviembre | 6 | 4 | 10 |
| 2017 Octubre | 4 | 5 | 9 |
| 2017 Septiembre | 4 | 11 | 15 |
| 2017 Agosto | 7 | 8 | 15 |
| 2017 Julio | 9 | 7 | 16 |
| 2017 Junio | 4 | 6 | 10 |
| 2017 Mayo | 4 | 7 | 11 |
| 2017 Abril | 4 | 2 | 6 |
| 2017 Marzo | 12 | 34 | 46 |
| 2017 Febrero | 5 | 3 | 8 |
| 2017 Enero | 7 | 1 | 8 |
| 2016 Diciembre | 15 | 4 | 19 |
| 2016 Noviembre | 21 | 7 | 28 |
| 2016 Octubre | 39 | 5 | 44 |
| 2016 Septiembre | 16 | 2 | 18 |
| 2016 Agosto | 13 | 1 | 14 |
| 2016 Julio | 9 | 8 | 17 |
| 2016 Junio | 7 | 13 | 20 |
| 2016 Mayo | 17 | 33 | 50 |
| 2016 Abril | 18 | 17 | 35 |
| 2016 Marzo | 16 | 20 | 36 |
| 2016 Febrero | 10 | 20 | 30 |
| 2016 Enero | 5 | 28 | 33 |
| 2015 Diciembre | 6 | 25 | 31 |
| 2015 Noviembre | 9 | 16 | 25 |
| 2015 Octubre | 14 | 20 | 34 |
| 2015 Septiembre | 7 | 10 | 17 |
| 2015 Agosto | 8 | 6 | 14 |
| 2015 Julio | 7 | 13 | 20 |
| 2015 Junio | 2 | 4 | 6 |
| 2015 Mayo | 8 | 6 | 14 |
| 2015 Abril | 8 | 17 | 25 |
| 2015 Marzo | 4 | 18 | 22 |
| 2015 Febrero | 2 | 4 | 6 |
| 2015 Enero | 10 | 6 | 16 |
| 2014 Diciembre | 20 | 6 | 26 |
| 2014 Noviembre | 13 | 2 | 15 |
| 2014 Octubre | 23 | 5 | 28 |
| 2014 Septiembre | 16 | 3 | 19 |
| 2014 Agosto | 16 | 2 | 18 |
| 2014 Julio | 12 | 2 | 14 |
| 2014 Junio | 14 | 4 | 18 |
| 2014 Mayo | 4 | 2 | 6 |
| 2014 Abril | 6 | 5 | 11 |
| 2014 Marzo | 9 | 1 | 10 |
| 2014 Febrero | 10 | 3 | 13 |
| 2014 Enero | 8 | 3 | 11 |
| 2013 Diciembre | 6 | 5 | 11 |
| 2013 Noviembre | 25 | 8 | 33 |
| 2013 Octubre | 22 | 7 | 29 |
| 2013 Septiembre | 11 | 6 | 17 |
| 2013 Agosto | 14 | 8 | 22 |
| 2013 Julio | 6 | 0 | 6 |
| 2009 Marzo | 605 | 0 | 605 |
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