Sarcomas paratesticulares en el paciente adulto. Manejo y evolución de la enfermedad
Adult paratesticular sarcomas. Management and evolution of the disease
C. Juan
, Astigueta Pérez*, Milagros Abad Licham**, Mariela Godoy Pow-Sang***, Víctor Destefano Urrutia***, Juvenal Sánchez Lihon**
,1
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jca_astigueta@hotmail.com
Correspondencia autor: Dr. Juan C. Astigueta Pérez Departamento de Cirugía Urológica. Instituto Regional de Enfermedades Neoplásicas - Norte Panamericana Norte km 558, Trujillo, Perú
Correspondencia autor: Dr. Juan C. Astigueta Pérez Departamento de Cirugía Urológica. Instituto Regional de Enfermedades Neoplásicas - Norte Panamericana Norte km 558, Trujillo, Perú
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Departamentos de" "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Patología.Instituto Nacional de Enfermedades Neoplásicas. Lima, Perú" "etiqueta" => "<span class="elsevierStyleSup">**</span>" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Urología Oncológica, Instituto Nacional de Enfermedades Neoplásicas. Lima, Perú" "etiqueta" => "<span class="elsevierStyleSup">***</span>" "identificador" => "aff0015" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "1" "correspondencia" => "Correspondencia autor: Dr. Juan C. Astigueta Pérez Departamento de Cirugía Urológica. Instituto Regional de Enfermedades Neoplásicas - Norte Panamericana Norte km 558, Trujillo, Perú" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Adult paratesticular sarcomas. Management and evolution of the disease" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2008-11-01" "fechaAceptado" => "2008-12-01" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec88996" "palabras" => array:3 [ 0 => "Sarcoma" 1 => "Paratesticular" 2 => "Adulto" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec88995" "palabras" => array:3 [ 0 => "Sarcoma" 1 => "Paratesticular" 2 => "Adult" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Identificar y analizar las características clínico-patológicas, terapéuticas y la evolución de la enfermedad en pacientes adultos con diagnostico de sarcoma paratesticular.</p> <span class="elsevierStyleSectionTitle">Material y Métodos</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Se revisaron retrospectivamente las historias clínicas de los pacientes con diagnóstico de sarcoma, de localización paratesticular del departamento de Urología del Instituto Nacional de Enfermedades Neoplásicas desde 1952 hasta el 2003. Se recopiló datos de filiación, antecedentes, sintomatología, métodos diagnósticos, estudios anatomopatologicos, tratamientos y estado de la enfermedad. Se analizó estadísticamente y evaluó comparativamente con la información obtenida en la revisión de la literatura.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Se encontraron dieciséis casos de sarcoma paratesticular en pacientes mayores de 16 años, 9 rabdomiosarcomas, 3 leiomiosarcomas, 3 liposarcomas y 1 sarcoma no clasificable. Hubo dos picos de presentación, uno entre 16 y 20 años y otro en mayores de 60 años. Seis tenían enfermedad metastásica al diagnóstico. La sobrevida en promedio fue de 32,18 meses con un rango entre 1 y 142 meses, sólo dos pacientes se encuentran vivos, un caso de rabdomiosarcoma sin evidencia de enfermedad y otro de leiomiosarcoma con recurrencia a nivel del canal inguinal (zona de cirugía).</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Los sarcomas paratesticulares son una neoplasia maligna rara de pobre pronóstico. El comportamiento biológico del tumor y la historia de enfermedad son variables de acuerdo al subtipo histológico, pero en general la evolución es tórpida con desenlace fatal.</p>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Identify and analyze the clinic pathologic characteristics, therapeutic, and the evolution of the disease in adult patients with a diagnosis of paratesticular sarcoma.</p> <span class="elsevierStyleSectionTitle">Material and Methods</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">We reviewed retrospectively the medical records of patients diagnosed with sarcoma paratesticular location of the department of urology at the National Institute of Neoplastic Diseases from 1952 to 2003. Data was collected affiliation, background, symptoms, diagnostic methods, pathological diagnosis, treatment and status of the disease. We analyzed statistically evaluated and compared with information obtained in the literature.</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Sixteen paratesticular sarcomas cases were found in patients greater than 16 years old; 9 rhabdomyosarcomas, 3 leiomyosarcomas, 3 liposarcomas, and 1 nonclassifiable sarcoma. There were two thresholds of presentation, one among 16 to 20 years and another one in greater than 60 years. Six had metastatic disease at diagnosis. The average survival was 32.18 months with a range among 1 and 142, only two patients are alive, a case of rhabdomyosarcoma without disease evidence and another one of leiomyosarcoma with inguinal recurrence.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Paratesticular sarcoma is a rare malignant neoplasia of poor prognostic. with variable history of disease in relation a histology subtype, but in general of bad evolution with fatal ending. The biological behavior of the tumor and history of the disease vary according to histological subtype, but in general the trend is poor with fatal outcome.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Referencias" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:26 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." 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| 2024 Noviembre | 0 | 3 | 3 |
| 2024 Octubre | 0 | 9 | 9 |
| 2024 Septiembre | 0 | 4 | 4 |
| 2024 Agosto | 0 | 2 | 2 |
| 2024 Julio | 0 | 5 | 5 |
| 2024 Junio | 0 | 12 | 12 |
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| 2024 Abril | 0 | 14 | 14 |
| 2024 Marzo | 0 | 39 | 39 |
| 2024 Febrero | 0 | 17 | 17 |
| 2024 Enero | 0 | 12 | 12 |
| 2023 Diciembre | 0 | 25 | 25 |
| 2023 Noviembre | 0 | 25 | 25 |
| 2023 Octubre | 0 | 34 | 34 |
| 2023 Septiembre | 0 | 19 | 19 |
| 2023 Agosto | 0 | 13 | 13 |
| 2023 Julio | 0 | 58 | 58 |
| 2023 Junio | 0 | 25 | 25 |
| 2023 Mayo | 0 | 23 | 23 |
| 2023 Abril | 0 | 7 | 7 |
| 2023 Marzo | 2 | 12 | 14 |
| 2023 Febrero | 0 | 12 | 12 |
| 2023 Enero | 0 | 11 | 11 |
| 2022 Diciembre | 0 | 16 | 16 |
| 2022 Noviembre | 0 | 6 | 6 |
| 2022 Octubre | 0 | 14 | 14 |
| 2022 Septiembre | 0 | 14 | 14 |
| 2022 Agosto | 0 | 15 | 15 |
| 2022 Julio | 0 | 17 | 17 |
| 2022 Junio | 0 | 10 | 10 |
| 2022 Mayo | 0 | 6 | 6 |
| 2022 Abril | 0 | 5 | 5 |
| 2022 Marzo | 0 | 9 | 9 |
| 2022 Febrero | 0 | 10 | 10 |
| 2022 Enero | 0 | 8 | 8 |
| 2021 Diciembre | 0 | 19 | 19 |
| 2021 Noviembre | 0 | 20 | 20 |
| 2021 Octubre | 0 | 11 | 11 |
| 2021 Septiembre | 0 | 16 | 16 |
| 2021 Agosto | 0 | 3 | 3 |
| 2021 Julio | 0 | 11 | 11 |
| 2021 Junio | 0 | 3 | 3 |
| 2021 Mayo | 0 | 30 | 30 |
| 2021 Abril | 0 | 65 | 65 |
| 2021 Marzo | 0 | 37 | 37 |
| 2021 Febrero | 0 | 23 | 23 |
| 2021 Enero | 0 | 14 | 14 |
| 2020 Diciembre | 0 | 23 | 23 |
| 2020 Noviembre | 0 | 17 | 17 |
| 2020 Octubre | 0 | 22 | 22 |
| 2020 Septiembre | 0 | 14 | 14 |
| 2020 Agosto | 0 | 17 | 17 |
| 2020 Julio | 0 | 13 | 13 |
| 2020 Junio | 0 | 12 | 12 |
| 2020 Mayo | 0 | 17 | 17 |
| 2020 Abril | 0 | 3 | 3 |
| 2020 Marzo | 0 | 6 | 6 |
| 2020 Febrero | 0 | 13 | 13 |
| 2020 Enero | 0 | 7 | 7 |
| 2019 Diciembre | 0 | 32 | 32 |
| 2019 Noviembre | 0 | 13 | 13 |
| 2019 Octubre | 0 | 22 | 22 |
| 2019 Septiembre | 0 | 13 | 13 |
| 2019 Agosto | 0 | 17 | 17 |
| 2019 Julio | 0 | 17 | 17 |
| 2019 Junio | 0 | 29 | 29 |
| 2019 Mayo | 0 | 102 | 102 |
| 2019 Abril | 0 | 49 | 49 |
| 2019 Marzo | 0 | 9 | 9 |
| 2019 Febrero | 0 | 14 | 14 |
| 2019 Enero | 0 | 10 | 10 |
| 2018 Diciembre | 0 | 15 | 15 |
| 2018 Noviembre | 0 | 21 | 21 |
| 2018 Octubre | 0 | 21 | 21 |
| 2018 Agosto | 0 | 4 | 4 |
| 2018 Julio | 0 | 4 | 4 |
| 2018 Marzo | 0 | 3 | 3 |
| 2018 Febrero | 0 | 12 | 12 |
| 2018 Enero | 1 | 16 | 17 |
| 2017 Diciembre | 0 | 9 | 9 |
| 2017 Noviembre | 5 | 17 | 22 |
| 2017 Octubre | 6 | 23 | 29 |
| 2017 Septiembre | 7 | 19 | 26 |
| 2017 Agosto | 5 | 19 | 24 |
| 2017 Julio | 11 | 20 | 31 |
| 2017 Junio | 11 | 22 | 33 |
| 2017 Mayo | 20 | 15 | 35 |
| 2017 Abril | 18 | 11 | 29 |
| 2017 Marzo | 15 | 56 | 71 |
| 2017 Febrero | 12 | 15 | 27 |
| 2017 Enero | 6 | 12 | 18 |
| 2016 Diciembre | 11 | 18 | 29 |
| 2016 Noviembre | 21 | 22 | 43 |
| 2016 Octubre | 29 | 31 | 60 |
| 2016 Septiembre | 12 | 34 | 46 |
| 2016 Agosto | 11 | 9 | 20 |
| 2016 Julio | 16 | 7 | 23 |
| 2016 Junio | 17 | 33 | 50 |
| 2016 Mayo | 23 | 53 | 76 |
| 2016 Abril | 11 | 30 | 41 |
| 2016 Marzo | 16 | 36 | 52 |
| 2016 Febrero | 12 | 19 | 31 |
| 2016 Enero | 16 | 23 | 39 |
| 2015 Diciembre | 19 | 22 | 41 |
| 2015 Noviembre | 8 | 16 | 24 |
| 2015 Octubre | 21 | 14 | 35 |
| 2015 Septiembre | 15 | 10 | 25 |
| 2015 Agosto | 10 | 8 | 18 |
| 2015 Julio | 6 | 13 | 19 |
| 2015 Junio | 1 | 10 | 11 |
| 2015 Mayo | 8 | 12 | 20 |
| 2015 Abril | 10 | 17 | 27 |
| 2015 Marzo | 7 | 20 | 27 |
| 2015 Febrero | 2 | 14 | 16 |
| 2015 Enero | 7 | 6 | 13 |
| 2014 Diciembre | 14 | 21 | 35 |
| 2014 Noviembre | 3 | 5 | 8 |
| 2014 Octubre | 13 | 5 | 18 |
| 2014 Septiembre | 17 | 5 | 22 |
| 2014 Agosto | 9 | 3 | 12 |
| 2014 Julio | 14 | 4 | 18 |
| 2014 Junio | 15 | 5 | 20 |
| 2014 Mayo | 7 | 3 | 10 |
| 2014 Abril | 6 | 4 | 10 |
| 2014 Marzo | 9 | 5 | 14 |
| 2014 Febrero | 6 | 2 | 8 |
| 2014 Enero | 4 | 4 | 8 |
| 2013 Diciembre | 9 | 2 | 11 |
| 2013 Noviembre | 14 | 2 | 16 |
| 2013 Octubre | 7 | 6 | 13 |
| 2013 Septiembre | 4 | 4 | 8 |
| 2013 Agosto | 3 | 9 | 12 |
| 2013 Julio | 3 | 3 | 6 |
| 2009 Mayo | 349 | 0 | 349 |
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