El índice de masa corporal y la dieta afectan el desarrollo del cáncer de próstata
Body mass index and diet affect prostate cancer development
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Mendoza, Argentina" "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Cátedra Clínica Urológica. Facultad de Ciencias Médicas. Universidad Nacional de Cuyo. Mendoza, Argentina" "etiqueta" => "<span class="elsevierStyleSup">**</span>" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "1" "correspondencia" => "Correspondencia autora: Prof. Constanza López Fontana Laboratorio de Enfermedades Metabólicas y Cáncer. Facultad de Farmacia y Bioquímica. Universidad Juan Agustín Maza. Acceso Este Lateral Sur 2245. (CP 5519) Guaymallén. Mendoza, Argentina. Tel. +54-261-4257535" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Body mass index and diet affect prostate cancer development" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2009-01-01" "fechaAceptado" => "2009-04-01" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec89079" "palabras" => array:8 [ 0 => "Cáncer de próstata" 1 => "Sobrepeso" 2 => "Índice de masa corporal" 3 => "Grasas saturadas" 4 => "Grasas monoinsaturadas" 5 => "Grasas poliinsaturadas" 6 => "Vitamina C" 7 => "Licopeno" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec89078" "palabras" => array:8 [ 0 => "Prostate cancer" 1 => "Overweight" 2 => "Body mass index" 3 => "Saturated fats" 4 => "Monounsaturated fats" 5 => "Polyunsaturated fats" 6 => "Vitamin C" 7 => "Lycopene" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span class="elsevierStyleSectionTitle">Introducción</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">El adenocarcinoma de próstata (CaP) es una de las causas más importantes de morbimortalidad en el mundo. La obesidad y los hábitos alimentarios inadecuados favorecerían el desarrollo del CaP. Objetivo: Analizar y comparar el índice de masa corporal (IMC) y la historia alimentaria, especialmente el consumo de grasas y antioxidantes, entre sujetos con CaP diagnosticado y sujetos libres de enfermedad.</p> <span class="elsevierStyleSectionTitle">Material y Métodos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">fueron seleccionados 40 hombres entre 50 y 80 años: 20 con cáncer de próstata diagnosticado y 20 libres de enfermedad como grupo control, a los cuales se les realizó tacto rectal, medición de antígeno prostático específico, ecografía transrectal y biopsia ecodirigida de próstata; y una entrevista nutricional que incluyó una historia dietética detallada y mediciones antropométricas. El análisis estadístico se realizó mediante Test de Student para muestras independientes (p&0,05).</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">El IMC en los sujetos con CaP fue superior que en los controles (29,8kg/m2 vs. 27,96kg/m2; p=0,13) aunque estadísticamente no significativo. Sin embargo, se observó una correlación directa entre el IMC y la agresividad del tumor (r=0,79; p<0.001). El consumo de grasas totales, saturadas, monoinsaturadas y poliinsaturadas fue significativamente mayor en los sujetos con CaP (p=0,001); mientras que la ingesta de ácidos grasos ?3, vitamina C y licopeno fue significativamente menor independientemente del Score de Gleason que presentasen (p<0,05).</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Un peso saludable y una alimentación baja en grasas totales, saturadas, monoinsaturadas y poliinsaturadas y rica en ácidos grasos ?3, vitamina C y licopeno se asocia a un menor riesgo de CaP.</p>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span class="elsevierStyleSectionTitle">Introduction</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Prostate cancer (CaP) is one of the most important causes of morbidity and mortality in the world. There is evidence that obesity and inadequate eating habits may promote CaP development.</p> <span class="elsevierStyleSectionTitle">Objective</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">To analyze and compare the body mass index (BMI) and the food intake, especially fats and antioxidants, among subjects with CaP and those free of disease as a control group.</p> <span class="elsevierStyleSectionTitle">Material and Methods</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">A sample of 40 men between 50 and 80 years old were selected for the study: 20 with CaP and 20 healthy men as control group. All volunteers underwent a digital rectal examination, prostate specific antigen level, ultrasound and transrectal prostate biopsy, and a nutritional interview where a dietary history and different anthropometric measurements were made. Statistical analysis was performed using the Student T test for independent samples (p <0.05).</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">BMI in the subjects with CaP was higher than in controls (29.8 kg/m2 vs. 27.96 kg/m2, p = 0.13) but not statistically significant. However, there was a direct correlation between BMI and tumor aggressiveness (r = 0.79, P <0.001). Total, saturated, monounsaturated and polyunsaturated fat intake was significantly higher in subjects with CaP; while ?3 fatty acids, vitamin C and lycopene intake was significantly lower than in controls (p <0.05).</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">A healthy weight and a diet low in total fat, saturated, monounsaturated and polyunsaturated fat and rich in ?3 fatty acids, vitamin C and lycopene is associated with a lower risk of CaP.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Referencias" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:29 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Obesity and prostate cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "S.J. Freedland" 1 => "W.J. 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| año/Mes | Html | Total | |
|---|---|---|---|
| 2024 Octubre | 0 | 12 | 12 |
| 2024 Septiembre | 0 | 7 | 7 |
| 2024 Agosto | 0 | 3 | 3 |
| 2024 Julio | 0 | 3 | 3 |
| 2024 Junio | 0 | 6 | 6 |
| 2024 Mayo | 0 | 6 | 6 |
| 2024 Abril | 0 | 10 | 10 |
| 2024 Marzo | 0 | 28 | 28 |
| 2024 Febrero | 0 | 8 | 8 |
| 2024 Enero | 0 | 18 | 18 |
| 2023 Diciembre | 0 | 13 | 13 |
| 2023 Noviembre | 0 | 15 | 15 |
| 2023 Octubre | 0 | 45 | 45 |
| 2023 Septiembre | 0 | 27 | 27 |
| 2023 Agosto | 0 | 9 | 9 |
| 2023 Julio | 0 | 88 | 88 |
| 2023 Junio | 0 | 13 | 13 |
| 2023 Mayo | 0 | 2 | 2 |
| 2023 Abril | 0 | 2 | 2 |
| 2023 Marzo | 0 | 1 | 1 |
| 2023 Febrero | 0 | 13 | 13 |
| 2023 Enero | 0 | 6 | 6 |
| 2022 Diciembre | 0 | 9 | 9 |
| 2022 Noviembre | 0 | 30 | 30 |
| 2022 Octubre | 0 | 7 | 7 |
| 2022 Septiembre | 0 | 18 | 18 |
| 2022 Agosto | 0 | 21 | 21 |
| 2022 Julio | 0 | 1 | 1 |
| 2022 Junio | 0 | 5 | 5 |
| 2022 Mayo | 0 | 4 | 4 |
| 2022 Abril | 0 | 12 | 12 |
| 2022 Marzo | 0 | 6 | 6 |
| 2022 Enero | 0 | 0 | 0 |
| 2021 Diciembre | 0 | 5 | 5 |
| 2021 Noviembre | 0 | 5 | 5 |
| 2021 Octubre | 0 | 3 | 3 |
| 2021 Septiembre | 0 | 0 | 0 |
| 2021 Agosto | 0 | 3 | 3 |
| 2021 Julio | 0 | 4 | 4 |
| 2021 Junio | 0 | 5 | 5 |
| 2021 Mayo | 0 | 5 | 5 |
| 2021 Abril | 0 | 2 | 2 |
| 2021 Marzo | 0 | 3 | 3 |
| 2021 Febrero | 0 | 5 | 5 |
| 2021 Enero | 0 | 8 | 8 |
| 2020 Diciembre | 0 | 8 | 8 |
| 2020 Noviembre | 0 | 3 | 3 |
| 2020 Octubre | 0 | 6 | 6 |
| 2020 Septiembre | 0 | 2 | 2 |
| 2020 Agosto | 0 | 5 | 5 |
| 2020 Julio | 0 | 4 | 4 |
| 2020 Mayo | 0 | 7 | 7 |
| 2020 Abril | 0 | 2 | 2 |
| 2020 Marzo | 0 | 13 | 13 |
| 2020 Febrero | 0 | 2 | 2 |
| 2020 Enero | 0 | 13 | 13 |
| 2019 Diciembre | 0 | 22 | 22 |
| 2019 Noviembre | 0 | 18 | 18 |
| 2019 Octubre | 0 | 3 | 3 |
| 2019 Septiembre | 0 | 11 | 11 |
| 2019 Agosto | 0 | 7 | 7 |
| 2019 Julio | 0 | 10 | 10 |
| 2019 Junio | 0 | 17 | 17 |
| 2019 Mayo | 0 | 46 | 46 |
| 2019 Abril | 0 | 55 | 55 |
| 2019 Marzo | 0 | 1 | 1 |
| 2019 Febrero | 0 | 12 | 12 |
| 2019 Enero | 0 | 12 | 12 |
| 2018 Diciembre | 0 | 9 | 9 |
| 2018 Noviembre | 0 | 9 | 9 |
| 2018 Octubre | 0 | 30 | 30 |
| 2018 Septiembre | 0 | 3 | 3 |
| 2018 Junio | 0 | 1 | 1 |
| 2018 Abril | 0 | 2 | 2 |
| 2018 Febrero | 2 | 5 | 7 |
| 2018 Enero | 1 | 9 | 10 |
| 2017 Diciembre | 2 | 6 | 8 |
| 2017 Noviembre | 6 | 8 | 14 |
| 2017 Octubre | 6 | 5 | 11 |
| 2017 Septiembre | 4 | 14 | 18 |
| 2017 Agosto | 5 | 3 | 8 |
| 2017 Julio | 10 | 14 | 24 |
| 2017 Junio | 10 | 14 | 24 |
| 2017 Mayo | 6 | 17 | 23 |
| 2017 Abril | 14 | 5 | 19 |
| 2017 Marzo | 13 | 18 | 31 |
| 2017 Febrero | 7 | 10 | 17 |
| 2017 Enero | 6 | 5 | 11 |
| 2016 Diciembre | 18 | 9 | 27 |
| 2016 Noviembre | 27 | 13 | 40 |
| 2016 Octubre | 24 | 8 | 32 |
| 2016 Septiembre | 12 | 15 | 27 |
| 2016 Agosto | 10 | 5 | 15 |
| 2016 Julio | 16 | 4 | 20 |
| 2016 Junio | 17 | 29 | 46 |
| 2016 Mayo | 17 | 44 | 61 |
| 2016 Abril | 16 | 32 | 48 |
| 2016 Marzo | 20 | 38 | 58 |
| 2016 Febrero | 18 | 33 | 51 |
| 2016 Enero | 13 | 35 | 48 |
| 2015 Diciembre | 17 | 25 | 42 |
| 2015 Noviembre | 4 | 17 | 21 |
| 2015 Octubre | 25 | 22 | 47 |
| 2015 Septiembre | 16 | 17 | 33 |
| 2015 Agosto | 12 | 10 | 22 |
| 2015 Julio | 12 | 8 | 20 |
| 2015 Junio | 7 | 5 | 12 |
| 2015 Mayo | 9 | 11 | 20 |
| 2015 Abril | 11 | 15 | 26 |
| 2015 Marzo | 12 | 12 | 24 |
| 2015 Febrero | 5 | 4 | 9 |
| 2015 Enero | 10 | 3 | 13 |
| 2014 Diciembre | 11 | 12 | 23 |
| 2014 Noviembre | 3 | 4 | 7 |
| 2014 Octubre | 16 | 3 | 19 |
| 2014 Septiembre | 12 | 0 | 12 |
| 2014 Agosto | 4 | 5 | 9 |
| 2014 Julio | 12 | 0 | 12 |
| 2014 Junio | 10 | 6 | 16 |
| 2014 Mayo | 8 | 2 | 10 |
| 2014 Abril | 6 | 4 | 10 |
| 2014 Marzo | 14 | 3 | 17 |
| 2014 Febrero | 10 | 3 | 13 |
| 2014 Enero | 5 | 2 | 7 |
| 2013 Diciembre | 6 | 2 | 8 |
| 2013 Noviembre | 12 | 3 | 15 |
| 2013 Octubre | 6 | 5 | 11 |
| 2013 Septiembre | 6 | 14 | 20 |
| 2013 Agosto | 4 | 8 | 12 |
| 2013 Julio | 1 | 3 | 4 |
| 2009 Junio | 317 | 0 | 317 |
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