Cistoprostatectomía radical robótica: análisis oncológico y funcional
Robotic radical cystoprostatectomy: oncological and functional analysis
Joan Palou Redorta1
, Josep María Gaya Sopena, Lluís Gausa Gascón, Francisco Sánchez-Martín, Antonio Rosales Bordes, Óscar Rodríguez Faba, Humberto Villavicencio Mavrich
Autor para correspondencia
jpalou@fundacio-puigvert.es
Correspondencia autor: Dr. Joan Palou Redorta Servicio de Urología. Fundació Puigvert Cartagena 340-350 - 08025 Barcelona Tel.: 934 169 700
Correspondencia autor: Dr. Joan Palou Redorta Servicio de Urología. Fundació Puigvert Cartagena 340-350 - 08025 Barcelona Tel.: 934 169 700
Unidad de Urología Oncológica, Servicio de Urología, Fundació Puigvert, Universidad Autónoma de Barcelona, Barcelona, España
Leído
2530
Vecesse ha leído el artículo
1414
Total PDF
1116
Total HTML
Compartir estadísticas
array:24 [ "pii" => "S0210480609742287" "issn" => "02104806" "doi" => "10.1016/S0210-4806(09)74228-7" "estado" => "S300" "fechaPublicacion" => "2009-01-01" "aid" => "74228" "copyright" => "Asociación Española de Urología (AEU)" "copyrightAnyo" => "2009" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Actas Urol Esp. 2009;33:759-66" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1950 "formatos" => array:3 [ "EPUB" => 7 "HTML" => 1116 "PDF" => 827 ] ] "itemSiguiente" => array:18 [ "pii" => "S0210480609742299" "issn" => "02104806" "doi" => "10.1016/S0210-4806(09)74229-9" "estado" => "S300" "fechaPublicacion" => "2009-01-01" "aid" => "74229" "copyright" => "Asociación Española de Urología (AEU)" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Actas Urol Esp. 2009;33:767-70" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 2094 "formatos" => array:3 [ "EPUB" => 6 "HTML" => 1242 "PDF" => 846 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Nefrectomía laparoscópica simple con asistencia de notes transvaginal y uso de instrumentos laparoscópicos estándar" "tienePdf" => array:2 [ 0 => "es" 1 => "en" ] "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "767" "paginaFinal" => "770" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Laparoscopic simple nephrectomy with transvaginal notes assistance and the use of standard laparoscopic instruments" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:2 [ "es" => true "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Octavio A. Castillo, Ivar Vidal-Mora, Rodrigo Campos, Alejandro Fonerón, Miguel Feria-Flores, Reinaldo Gómez, Francisco Sepúlveda" "autores" => array:7 [ 0 => array:2 [ "nombre" => "Octavio A." "apellidos" => "Castillo" ] 1 => array:2 [ "nombre" => "Ivar" "apellidos" => "Vidal-Mora" ] 2 => array:2 [ "nombre" => "Rodrigo" "apellidos" => "Campos" ] 3 => array:2 [ "nombre" => "Alejandro" "apellidos" => "Fonerón" ] 4 => array:2 [ "nombre" => "Miguel" "apellidos" => "Feria-Flores" ] 5 => array:2 [ "nombre" => "Reinaldo" "apellidos" => "Gómez" ] 6 => array:2 [ "nombre" => "Francisco" "apellidos" => "Sepúlveda" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210480609742299?idApp=UINPBA00004N" "url" => "/02104806/0000003300000007/v1_201304251940/S0210480609742299/v1_201304251940/es/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S0210480609742275" "issn" => "02104806" "doi" => "10.1016/S0210-4806(09)74227-5" "estado" => "S300" "fechaPublicacion" => "2009-01-01" "aid" => "74227" "copyright" => "Asociación Española de Urología (AEU)" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Actas Urol Esp. 2009;33:755-8" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1521 "formatos" => array:3 [ "EPUB" => 6 "HTML" => 738 "PDF" => 777 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Nefrectomía radical laparoscópica en piezas quirúrgicas de gran tamaño" "tienePdf" => array:2 [ 0 => "es" 1 => "en" ] "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "755" "paginaFinal" => "758" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Laparoscopic radial nephrectomy in big surgical specimens" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:2 [ "es" => true "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Sergio Alonso, Gregorio, S. Sánchez, C. Soler, A. Rando, M. Girón, J. Ángel Tabernero Gómez, A. Aguilera, Jesús Cisneros Ledo, Javier de la Peña Barthel" "autores" => array:10 [ 0 => array:2 [ "nombre" => "Sergio" "apellidos" => "Alonso" ] 1 => array:1 [ "apellidos" => "Gregorio" ] 2 => array:2 [ "nombre" => "S." "apellidos" => "Sánchez" ] 3 => array:2 [ "nombre" => "C." "apellidos" => "Soler" ] 4 => array:2 [ "nombre" => "A." "apellidos" => "Rando" ] 5 => array:2 [ "nombre" => "M." "apellidos" => "Girón" ] 6 => array:2 [ "nombre" => "J." "apellidos" => "Ángel Tabernero Gómez" ] 7 => array:2 [ "nombre" => "A." "apellidos" => "Aguilera" ] 8 => array:2 [ "nombre" => "Jesús" "apellidos" => "Cisneros Ledo" ] 9 => array:2 [ "nombre" => "Javier" "apellidos" => "de la Peña Barthel" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210480609742275?idApp=UINPBA00004N" "url" => "/02104806/0000003300000007/v1_201304251940/S0210480609742275/v1_201304251940/es/main.assets" ] "es" => array:14 [ "idiomaDefecto" => true "titulo" => "Cistoprostatectomía radical robótica: análisis oncológico y funcional" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "759" "paginaFinal" => "766" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Joan Palou Redorta, Josep María Gaya Sopena, Lluís Gausa Gascón, Francisco Sánchez-Martín, Antonio Rosales Bordes, Óscar Rodríguez Faba, Humberto Villavicencio Mavrich" "autores" => array:7 [ 0 => array:4 [ "nombre" => "Joan" "apellidos" => "Palou Redorta" "email" => array:1 [ 0 => "jpalou@fundacio-puigvert.es" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "Josep" "apellidos" => "María Gaya Sopena" ] 2 => array:2 [ "nombre" => "Lluís" "apellidos" => "Gausa Gascón" ] 3 => array:2 [ "nombre" => "Francisco" "apellidos" => "Sánchez-Martín" ] 4 => array:2 [ "nombre" => "Antonio" "apellidos" => "Rosales Bordes" ] 5 => array:2 [ "nombre" => "Óscar" "apellidos" => "Rodríguez Faba" ] 6 => array:2 [ "nombre" => "Humberto" "apellidos" => "Villavicencio Mavrich" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Unidad de Urología Oncológica, Servicio de Urología, Fundació Puigvert, Universidad Autónoma de Barcelona, Barcelona, España" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "1" "correspondencia" => "Correspondencia autor: Dr. Joan Palou Redorta Servicio de Urología. Fundació Puigvert Cartagena 340-350 - 08025 Barcelona Tel.: 934 169 700" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Robotic radical cystoprostatectomy: oncological and functional analysis" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2009-03-01" "fechaAceptado" => "2009-04-01" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec89049" "palabras" => array:6 [ 0 => "Cáncer de vejiga" 1 => "Cistectomía radical" 2 => "Laparoscopia" 3 => "Linfadenectomía" 4 => "Robot" 5 => "Derivación urinaria" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec89048" "palabras" => array:6 [ 0 => "Bladder neoplasm" 1 => "Laparoscopy" 2 => "Lymphadenectomy" 3 => "radical cystectomy" 4 => "Robot" 5 => "Urinary diversion" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span class="elsevierStyleSectionTitle">Introducción</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">La cirugía laparoscópica robotizada da Vinci, ha demostrado en la prostatectomía radical, óptimos resultados funcionales y oncológicos con menor curva de aprendizaje, mayor comodidad y visión para el cirujano, y correcta preservación de las bandeletas neurovasculares. Esto ha dado lugar a que iniciar la experiencia con cistectomía radical robótica (CRR), fuera de nuestro país.</p> <span class="elsevierStyleSectionTitle">Objetivos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Revisar nuestra experiencia inicial en CRR, valorando los resultados quirúrgicos y funcionales obtenidos, y complicaciones inmediatas y a corto plazo.</p> <span class="elsevierStyleSectionTitle">Pacientes y método</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Entre diciembre del 2007 y enero del 2009 hemos realizado nueve cistoprostatectomías radicales robóticas y en siete de los nueve casos con linfadenectomía (LDN) robótica. En 5 pacientes por tumor músculo-invasivo y 4 por no músculoinvasivo de alto riesgo. La mediana de edad fue 57 años (rango 34-81). La derivación urinaria se realizó extracorpóreamente, en 3 casos un conducto ileal, en los 6 restantes una neovejiga tipo Studer, en 3 de estos 6 casos la anastomosis uretro-neovejiga se realizó intracorpóreamente.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">El tiempo medio total de cirugía fue 300 minutos (rango 280-420) en el conducto ileal y 360 (rango 330-540) en el Studer. Ningún caso requirió conversión ni transfusión sanguínea. La mediana de ganglios extraidos mediante LDN robótica fue 10 (rango 6-18). La AP de la pieza reveló 3 pT0, 2 CIS, 3 pT3, 1 pT4b (márgenes positivos). Con mediana de seguimiento de 7 meses no se ha observado ningún implante peritoneal y únicamente una estenosis ureteral. Se inició dieta oral en 5 casos a las 48 horas. De los 6 pacientes con función sexual conservada preoperatoria y seguimiento > 3 meses, 2 tenían erección completa al mes, 2 a los 3 y 6 meses, y los 2 restantes presentan erección completa con inhib de la 5PDE a los 3 y 9 meses. Todos los pacientes con neovejiga presentan correcta continencia diurna. La estancia media hospitalaria fue de 8,5 días (rango 7-19).</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">La cistectomía radical más linfadenectomía robótica, con reconstrucción extracorpórea de la derivación urinaria ofrece buenos resultados quirúrgicos y funcionales tempranos. La preservación cuidadosa de las bandeletas neurovasculares en esta cirugía radical pélvica permite obtener excelentes resultados en la función sexual y miccional.</p>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span class="elsevierStyleSectionTitle">Introduction</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">The da Vinci robotic laparoscopic surgery, has been shown in radical prostatectomy, optimal functional and oncological results with a lower learning curve, greater comfort and vision for the surgeon, and proper preservation of the neurovascular bundles. This has led to begin the experience with robotic radical cystectomy (RRC).</p> <span class="elsevierStyleSectionTitle">Objectives</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Review our initial experience in CRR, evaluating surgical and functional results obtained, and also immediate and short-term complications.</p> <span class="elsevierStyleSectionTitle">Material and methods</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Between December 2007 and January 2009 we performed nine robotic radical cystoprostatectomy and in seven patients robotic lymphadenectomy (LDN). Five patients had a muscle-invasive disease and 4 non-muscle invasive bladder cancer. The median age was 57 years (range 34-81). Urinary diversion was performed extracorporeally in all cases, 3 cases an ileal conduit and 6 an Studer neobladder in 3 of these 6 cases, the urethra-neobladder anastomosis was performed intracorporeally.</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">The average time of surgery was 300 minutes (range 280-420) in the ileal conduit and 360 (range 330-540) in the Studer. No cases required conversion or blood transfusion. The median number of nodes removed by LDN robotics was 10 (range 6-18). The pathology revealed 3 pT0, 2 CIS, 3 pT3, 1 pT4b (positive margins). With a median follow up of 7 months there have been no peritoneal implant and only one ureteral stenosis. Oral diet was initiated in 5 cases at 48 hours. Of the 6 patients with preserved sexual function preoperatively and followup of more than 3 months, 2 had full erection at 1 month, 2 at 3 and 6 months, and the remaining 2 presented with a full erection with 5 PD inhibitors at 3 and 9 months. All patients with neobladder presented correct daytime continence. The average hospital stay was 8.5 days (range 7-19).</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">The radical robotic cystectomy with extracorporeal reconstruction of the urinary diversion offers good early functional and surgical outcomes. The careful preservation of the neurovascular bundles in radical pelvic surgery provides excellent results in urinary and sexual function.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Referencias" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:34 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Laparoscopic radical prostatectomy: oncological evaluation after 1000 cases a Montsouris Institute" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "B. Guillonneau" 1 => "H. el-Fettouh" 2 => "H. Baumert" 3 => "X. Cathelineau" 4 => "J.D. Doublet" 5 => "G. Fromont" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/01.ju.0000055141.36916.be" "Revista" => array:7 [ "tituloSerie" => "J Urol" "fecha" => "2003" "volumen" => "169" "numero" => "4" "paginaInicial" => "1261" "paginaFinal" => "1266" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12629339" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Laparoscopic cystectomy: initial report for a new treatment for the retained bladder" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "R.O. Parra" 1 => "C.H. Andrus" 2 => "J.P. Jones" 3 => "J.A. Boullier" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "J Urol" "fecha" => "1992" "volumen" => "148" "numero" => "4" "paginaInicial" => "1140" "paginaFinal" => "1144" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1404624" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "CR radical y conducto ileal laparoscópico" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "E. Sánchez de Badajoz" 1 => "J.L. Gallego" 2 => "A. Reche" 3 => "J.M. Gutíerrez de la Cruz" 4 => "A. Jiménez" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Arch Esp Urol" "fecha" => "1993" "volumen" => "46" "numero" => "7" "paginaInicial" => "621" "paginaFinal" => "624" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8239740" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Comparasion between open and laparoscopic assisted radical cystectomy for bladder cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "G.P. Haber" 1 => "S.C. Campbell" 2 => "J.R. Colombo" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "J Urol" "fecha" => "2007" "volumen" => "177" "paginaInicial" => "548" ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Open vs laparoscopy-assisted radical cystectomy: results of a prospective study" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "F. Porpiglia" 1 => "J. Renard" 2 => "M. Billia" 3 => "C. Scoffone" 4 => "C. Cracco" 5 => "C. Terrone" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1089/end.2006.0224" "Revista" => array:7 [ "tituloSerie" => "J Endourol" "fecha" => "2007" "volumen" => "21" "numero" => "3" "paginaInicial" => "325" "paginaFinal" => "329" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17444780" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Nerve-sparing robot-assisted radical cystoprostatectomy and urinary diversion" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M. Menon" 1 => "A.K. Hemal" 2 => "A. Tewari" 3 => "A. Shrivastava" 4 => "A.M. Shoma" 5 => "N.A. El-Tabey" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "BJU Int" "fecha" => "2003" "volumen" => "92" "numero" => "3" "paginaInicial" => "232" "paginaFinal" => "236" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12887473" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0035" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Tension and energy-free robotic-assisted laparoscopic radical prostatectomy with interfascial dissection of the neurovasculars bundles" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "A. Mattei" 1 => "R. Naspro" 2 => "F. Annino" 3 => "D. Burke" 4 => "R. Guida Jr" 5 => "R. Gasron" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.eururo.2007.05.029" "Revista" => array:7 [ "tituloSerie" => "Eur Urol" "fecha" => "2007" "volumen" => "52" "numero" => "3" "paginaInicial" => "687" "paginaFinal" => "694" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17587488" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0040" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Villavicencio H, Esquena S, Salvador J, Gómez-Ruiz JJ, Escovar La Riva P, Palou J. Prostatectomía radical robótica: análisis después de 100 casos en la Fundació Puigvert. Act Urol Esp. 2009, en prensa" ] ] ] 8 => array:3 [ "identificador" => "bib0045" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Evolution of robotic radical prostatectomy: assessment after 2766 procedures" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "K.K. Badani" 1 => "S. Kaul" 2 => "M. Menon" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1002/cncr.23027" "Revista" => array:7 [ "tituloSerie" => "Cancer" "fecha" => "2007" "volumen" => "110" "numero" => "9" "paginaInicial" => "1951" "paginaFinal" => "1958" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17893904" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib0050" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Robotic radical cystectomy and urinary diversion in the management of bladder cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A.K. Hemal" 1 => "H. Abol-Enein" 2 => "A. Tewari" 3 => "A. Shrivastava" 4 => "A.M. Shoma" 5 => "M.A. Ghoneim" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.ucl.2004.06.009" "Revista" => array:7 [ "tituloSerie" => "Urol Clin North AM" "fecha" => "2004" "volumen" => "31" "numero" => "4 special issue" "paginaInicial" => "719" "paginaFinal" => "729" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15474598" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib0055" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Robotic-assisted laparoscopic radical cystoprostatectomy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "R.S. Pruthi" 1 => "E.M. Wallen" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.eururo.2007.03.067" "Revista" => array:7 [ "tituloSerie" => "Eur Urol" "fecha" => "2008" "volumen" => "53" "numero" => "2" "paginaInicial" => "310" "paginaFinal" => "322" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17400365" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib0060" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Robotic vs.open radical cystectomy: prospective comparasion of perioperative outcomes and pathological measures of early oncological efficacy" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "G.J. Wang" 1 => "D.A. Barocas" 2 => "J.D. Raman" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1464-410X.2007.07212.x" "Revista" => array:7 [ "tituloSerie" => "BJU Int" "fecha" => "2008" "volumen" => "101" "numero" => "1" "paginaInicial" => "89" "paginaFinal" => "93" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17888044" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib0065" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Role of robot-assisted surgery for bladder cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "A.K. Hemal" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/MOU.0b013e32831c50b4" "Revista" => array:7 [ "tituloSerie" => "Curr Opin Urol" "fecha" => "2009" "volumen" => "19" "numero" => "1" "paginaInicial" => "69" "paginaFinal" => "75" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19057220" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib0070" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Open versus laparoscopy-assisted radical cystectomy: results of a prospective study" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "F. Porpiglia" 1 => "J. Renard" 2 => "M. Billia" 3 => "C. Scoffone" 4 => "C. Cracco" 5 => "C. Terrone" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1089/end.2006.0224" "Revista" => array:7 [ "tituloSerie" => "J Endourol" "fecha" => "2007" "volumen" => "21" "numero" => "3" "paginaInicial" => "325" "paginaFinal" => "329" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17444780" "web" => "Medline" ] ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib0075" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Laparoscopic assisted radical cystectomy with ileal neobladder: a comparasion with the open approach" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "J.B. Basillote" 1 => "C. Abdelsheid" 2 => "T.E. Ahlering" 3 => "A.M. Shanberg" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/01.ju.0000129662.83162.2e" "Revista" => array:7 [ "tituloSerie" => "J Urol" "fecha" => "2004" "volumen" => "172" "numero" => "2" "paginaInicial" => "489" "paginaFinal" => "493" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15247711" "web" => "Medline" ] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib0080" "etiqueta" => "16." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cistectomía radical laparoscópica en tumors vesicales clínicamente localizados (T2" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "L. Cecchini" 1 => "A. Orsola" 2 => "C. Raventos" 3 => "E. Trilla" 4 => "J. Morote" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Arch. Esp. Urol. v" "fecha" => "2008" "volumen" => "61 n" "numero" => "4" ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib0085" "etiqueta" => "17." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Comparative analysis of early perioperative outcomes following radical cystectomy by either the robotic or open method" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "A. Galich" 1 => "S. Sterrett" 2 => "T. Nazemi" 3 => "G. Pohlman" 4 => "L. Smith" 5 => "K.C. Balaji" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "JSLS" "fecha" => "2006" "volumen" => "10" "numero" => "2" "paginaInicial" => "145" "paginaFinal" => "150" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16882409" "web" => "Medline" ] ] ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib0090" "etiqueta" => "18." "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Beecken WD, Wolfram M, Engl T, Bentas W, Probst M, Blaheta R et al. Robotic-assisted laparoscopic radical cystectomy and intra-abdominal formation of an orthotopic ileal neobladder. Eur Urol 44(3) 337-339." ] ] ] 18 => array:3 [ "identificador" => "bib0095" "etiqueta" => "19." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Derivaciones urinarias laparoscópicas" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "S. Alonso Gregorio" 1 => "M. Alvarez Maestro" 2 => "P.M. Cabrera Castillo" 3 => "A. Tabernero Gómez" 4 => "R. Cansino Alcaide" 5 => "J. Cisneros Ledo" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Actas Urol Esp" "fecha" => "2008" "volumen" => "32" "numero" => "9" "paginaInicial" => "908" "paginaFinal" => "915" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19044301" "web" => "Medline" ] ] ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib0100" "etiqueta" => "20." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Laparoscopyassisted robotic radical cystoprostatectomy with ileal conduit urinary diversion for muscle-invasive bladder cancer: initial two cases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "P. Yohannes" 1 => "V. Puri" 2 => "B. Yi" 3 => "A.K. Khan" 4 => "R. Sudan" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1089/089277903770802254" "Revista" => array:7 [ "tituloSerie" => "J Endourol" "fecha" => "2003" "volumen" => "17" "numero" => "9" "paginaInicial" => "729" "paginaFinal" => "732" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14642031" "web" => "Medline" ] ] ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib0105" "etiqueta" => "21." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "3rd Feasibility of robot-assisted totally intracorporeal laparoscopic ileal conduit urinary diversion: initial results of a single institutional pilot study" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "K.C. Balaji" 1 => "P. Yohannes" 2 => "C.L. McBride" 3 => "D. Oleynikov" 4 => "G.P. Hemstreet" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.urology.2004.01.015" "Revista" => array:7 [ "tituloSerie" => "Urology" "fecha" => "2004" "volumen" => "63" "numero" => "1" "paginaInicial" => "51" "paginaFinal" => "55" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15013653" "web" => "Medline" ] ] ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib0110" "etiqueta" => "22." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Initial experience with successful totally robotic laparoscopic cystoprostatectomy and ileal conduit construction in tetraplegic patients: report of two cases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "J. Hubert" 1 => "M. Chammas" 2 => "S. Larre" 3 => "B. Feuillu" 4 => "F. Cheng" 5 => "J.M. Beis" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1089/end.2006.20.139" "Revista" => array:7 [ "tituloSerie" => "J Endourol" "fecha" => "2006" "volumen" => "20" "numero" => "2" "paginaInicial" => "139" "paginaFinal" => "143" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16509801" "web" => "Medline" ] ] ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bib0115" "etiqueta" => "23." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Robot-assisted laparoscopic radical cystoprostatectomy and totally intracorporeal ileal neobladder" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "L.G. Sala" 1 => "G.S. Matsunaga" 2 => "F.A. Corica" 3 => "D.K. Ornstein" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1089/end.2006.20.233" "Revista" => array:7 [ "tituloSerie" => "J Endourol" "fecha" => "2006" "volumen" => "20" "numero" => "4" "paginaInicial" => "233" "paginaFinal" => "235" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16646646" "web" => "Medline" ] ] ] ] ] ] ] ] 23 => array:3 [ "identificador" => "bib0120" "etiqueta" => "24." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Laparoscopic and Robotic Assisted Radical Cystectomy for Bladder Cancer: A Critical Analysis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "G.P. Haber" 1 => "S. Crouzet" 2 => "I.S. Gill" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.eururo.2008.03.076" "Revista" => array:7 [ "tituloSerie" => "Eur Urol" "fecha" => "2008" "volumen" => "54" "numero" => "1" "paginaInicial" => "54" "paginaFinal" => "62" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18403100" "web" => "Medline" ] ] ] ] ] ] ] ] 24 => array:3 [ "identificador" => "bib0125" "etiqueta" => "25." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Extent of pelvic lymphadenectomy and its impact on outcome in patients diagnosed with bladder cancer: analysis of data from the Surveillance, Epidemiology and End Results Program database" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "B.R. Konety" 1 => "S.A. Josyln" 2 => "M.A. O’Donell" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/01.ju.0000052721.61645.a3" "Revista" => array:7 [ "tituloSerie" => "J Urol" "fecha" => "2003" "volumen" => "169" "numero" => "3" "paginaInicial" => "946" "paginaFinal" => "950" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12576819" "web" => "Medline" ] ] ] ] ] ] ] ] 25 => array:3 [ "identificador" => "bib0130" "etiqueta" => "26." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Evaluation of the relevance of lymph node density in a contemporany series of patients undergoing radical cystectomy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "W. Kassouf" 1 => "D. Leibovidici" 2 => "M.F. Munsell" 3 => "C.P. Dinney" 4 => "A.M. Kamat" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/S0022-5347(06)00510-6" "Revista" => array:7 [ "tituloSerie" => "J Urol" "fecha" => "2006" "volumen" => "176" "numero" => "1" "paginaInicial" => "53" "paginaFinal" => "57" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16753366" "web" => "Medline" ] ] ] ] ] ] ] ] 26 => array:3 [ "identificador" => "bib0135" "etiqueta" => "27." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Superiority of ratio based lymph nodestaging for bladder cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "H.W. Herr" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/01.ju.0000032474.22093.06" "Revista" => array:7 [ "tituloSerie" => "J Urol" "fecha" => "2003" "volumen" => "169" "numero" => "3" "paginaInicial" => "943" "paginaFinal" => "945" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12576818" "web" => "Medline" ] ] ] ] ] ] ] ] 27 => array:3 [ "identificador" => "bib0140" "etiqueta" => "28." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Utilidad de la linfadenectomía en el cáncer de vejiga. Revisión de la literatura" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "J.I. Monzó" 1 => "F. Herranz Amo" 2 => "R. Cabello Benavente" 3 => "C. Hernández Fernández" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Actas Urol Esp" "fecha" => "2007" "volumen" => "31" "numero" => "1" "paginaInicial" => "1" "paginaFinal" => "6" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17410978" "web" => "Medline" ] ] ] ] ] ] ] ] 28 => array:3 [ "identificador" => "bib0145" "etiqueta" => "29." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "CR radical laparoscópica" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "O. Castillo" 1 => "R. Cabello" 2 => "G. Briones" 3 => "C. Hernández" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Actas Urol Esp" "fecha" => "2006" "volumen" => "30" "numero" => "5" "paginaInicial" => "531" "paginaFinal" => "540" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16884106" "web" => "Medline" ] ] ] ] ] ] ] ] 29 => array:3 [ "identificador" => "bib0150" "etiqueta" => "30." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Recoverability of erectile function in post-radical cystectomy patients: subjective and objective evaluation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "I.A. Hekal" 1 => "M.S. El-Bahnasawy" 2 => "A. Moshah" 3 => "A. El-Assmy" 4 => "A. Shaaben" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.eururo.2007.07.042" "Revista" => array:6 [ "tituloSerie" => "Eur Urol" "fecha" => "2008" "volumen" => "53" "numero" => "6" "paginaInicial" => "1193" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17709172" "web" => "Medline" ] ] ] ] ] ] ] ] 30 => array:3 [ "identificador" => "bib0155" "etiqueta" => "31." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Robot-assisted radical cystectomy and urinary diversion in female patients: technique with preservation of the uterus and vagina" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "M. Menon" 1 => "A.K. Hemal" 2 => "A. Tewari" 3 => "A. Shrivastava" 4 => "A.M. Shoma" 5 => "H. Abol-Ein" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jamcollsurg.2003.11.010" "Revista" => array:7 [ "tituloSerie" => "J Am Coll Surg" "fecha" => "2004" "volumen" => "198" "numero" => "3" "paginaInicial" => "386" "paginaFinal" => "393" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14992741" "web" => "Medline" ] ] ] ] ] ] ] ] 31 => array:3 [ "identificador" => "bib0160" "etiqueta" => "32." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Laparoscopic radical cystectomy with continent urinary diversion (rectosigmoid pouch) performed completely intracorporeally: an intermediate functional and oncologic analysis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "S. Deger" 1 => "R. Peters" 2 => "J. Roigas" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.urology.2004.07.004" "Revista" => array:7 [ "tituloSerie" => "Urology" "fecha" => "2004" "volumen" => "64" "numero" => "5" "paginaInicial" => "935" "paginaFinal" => "939" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15533481" "web" => "Medline" ] ] ] ] ] ] ] ] 32 => array:3 [ "identificador" => "bib0165" "etiqueta" => "33." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Port site metastases after robotassisted laparoscopic radical cystectomy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "N.A. El-Tabey" 1 => "A.M. Shoma" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.urology.2005.06.074" "Revista" => array:6 [ "tituloSerie" => "Urology" "fecha" => "2005" "volumen" => "66" "numero" => "5" "paginaInicial" => "1110" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16286148" "web" => "Medline" ] ] ] ] ] ] ] ] 33 => array:3 [ "identificador" => "bib0170" "etiqueta" => "34." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Preoperative risk stratification predicts likelihood of concurrent PSA-free survival, continence, and potency (the trifecta analysis) after radical retropubic prostatectomy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "P.M. Pierorazio" 1 => "B.A. Spencer" 2 => "T.R. McCann" 3 => "J.M. McKiernan" 4 => "M.C. Benson" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.urology.2007.06.639" "Revista" => array:6 [ "tituloSerie" => "Urology" "fecha" => "2007" "volumen" => "70" "paginaInicial" => "717" "paginaFinal" => "722" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17991543" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "es" "url" => "/02104806/0000003300000007/v1_201304251940/S0210480609742287/v1_201304251940/es/main.assets" "Apartado" => array:4 [ "identificador" => "6429" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Original" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/02104806/0000003300000007/v1_201304251940/S0210480609742287/v1_201304251940/es/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210480609742287?idApp=UINPBA00004N" "pdfAlternativo" => array:1 [ 0 => array:3 [ "idioma" => "en" "documentoPdf" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/file/02104806/addon/S0210480609742287/S300/en/292v33n07a13143214pdf001_2.pdf" "portada" => "292v33n07a13143214pdf001_2.png" ] ] ]
| año/Mes | Html | Total | |
|---|---|---|---|
| 2024 Octubre | 0 | 5 | 5 |
| 2024 Septiembre | 0 | 5 | 5 |
| 2024 Agosto | 0 | 6 | 6 |
| 2024 Julio | 0 | 4 | 4 |
| 2024 Junio | 0 | 9 | 9 |
| 2024 Mayo | 0 | 5 | 5 |
| 2024 Abril | 0 | 14 | 14 |
| 2024 Marzo | 0 | 35 | 35 |
| 2024 Febrero | 0 | 9 | 9 |
| 2024 Enero | 0 | 19 | 19 |
| 2023 Diciembre | 0 | 21 | 21 |
| 2023 Noviembre | 0 | 38 | 38 |
| 2023 Octubre | 0 | 41 | 41 |
| 2023 Septiembre | 0 | 7 | 7 |
| 2023 Agosto | 0 | 19 | 19 |
| 2023 Julio | 0 | 81 | 81 |
| 2023 Junio | 0 | 13 | 13 |
| 2023 Mayo | 0 | 2 | 2 |
| 2023 Abril | 0 | 2 | 2 |
| 2023 Marzo | 0 | 14 | 14 |
| 2023 Febrero | 0 | 9 | 9 |
| 2023 Enero | 0 | 6 | 6 |
| 2022 Diciembre | 0 | 12 | 12 |
| 2022 Noviembre | 0 | 5 | 5 |
| 2022 Octubre | 0 | 6 | 6 |
| 2022 Septiembre | 0 | 24 | 24 |
| 2022 Agosto | 0 | 51 | 51 |
| 2022 Julio | 0 | 6 | 6 |
| 2022 Junio | 0 | 9 | 9 |
| 2022 Mayo | 0 | 8 | 8 |
| 2022 Abril | 0 | 12 | 12 |
| 2022 Marzo | 0 | 12 | 12 |
| 2022 Febrero | 0 | 2 | 2 |
| 2021 Diciembre | 0 | 3 | 3 |
| 2021 Noviembre | 0 | 2 | 2 |
| 2021 Agosto | 0 | 5 | 5 |
| 2021 Julio | 0 | 2 | 2 |
| 2021 Junio | 0 | 3 | 3 |
| 2021 Mayo | 0 | 2 | 2 |
| 2021 Abril | 0 | 9 | 9 |
| 2021 Marzo | 0 | 5 | 5 |
| 2021 Febrero | 0 | 3 | 3 |
| 2021 Enero | 0 | 2 | 2 |
| 2020 Diciembre | 0 | 3 | 3 |
| 2020 Noviembre | 0 | 2 | 2 |
| 2020 Octubre | 0 | 5 | 5 |
| 2020 Septiembre | 0 | 10 | 10 |
| 2020 Agosto | 0 | 1 | 1 |
| 2020 Julio | 0 | 4 | 4 |
| 2020 Junio | 0 | 2 | 2 |
| 2020 Mayo | 0 | 4 | 4 |
| 2020 Abril | 0 | 2 | 2 |
| 2020 Marzo | 0 | 5 | 5 |
| 2020 Febrero | 0 | 4 | 4 |
| 2020 Enero | 0 | 10 | 10 |
| 2019 Diciembre | 0 | 21 | 21 |
| 2019 Noviembre | 0 | 6 | 6 |
| 2019 Octubre | 0 | 8 | 8 |
| 2019 Septiembre | 0 | 6 | 6 |
| 2019 Agosto | 0 | 6 | 6 |
| 2019 Julio | 0 | 8 | 8 |
| 2019 Junio | 0 | 21 | 21 |
| 2019 Mayo | 0 | 67 | 67 |
| 2019 Abril | 0 | 41 | 41 |
| 2019 Marzo | 0 | 12 | 12 |
| 2019 Febrero | 0 | 14 | 14 |
| 2019 Enero | 0 | 7 | 7 |
| 2018 Diciembre | 0 | 13 | 13 |
| 2018 Noviembre | 0 | 22 | 22 |
| 2018 Octubre | 0 | 12 | 12 |
| 2018 Septiembre | 0 | 1 | 1 |
| 2018 Agosto | 0 | 15 | 15 |
| 2018 Julio | 0 | 1 | 1 |
| 2018 Junio | 0 | 7 | 7 |
| 2018 Mayo | 0 | 12 | 12 |
| 2018 Abril | 0 | 2 | 2 |
| 2018 Marzo | 0 | 3 | 3 |
| 2018 Febrero | 2 | 7 | 9 |
| 2018 Enero | 0 | 7 | 7 |
| 2017 Diciembre | 3 | 6 | 9 |
| 2017 Noviembre | 1 | 10 | 11 |
| 2017 Octubre | 5 | 4 | 9 |
| 2017 Septiembre | 6 | 13 | 19 |
| 2017 Agosto | 7 | 8 | 15 |
| 2017 Julio | 7 | 1 | 8 |
| 2017 Junio | 7 | 17 | 24 |
| 2017 Mayo | 11 | 12 | 23 |
| 2017 Abril | 14 | 2 | 16 |
| 2017 Marzo | 16 | 12 | 28 |
| 2017 Febrero | 8 | 2 | 10 |
| 2017 Enero | 6 | 5 | 11 |
| 2016 Diciembre | 32 | 7 | 39 |
| 2016 Noviembre | 38 | 7 | 45 |
| 2016 Octubre | 25 | 15 | 40 |
| 2016 Septiembre | 13 | 7 | 20 |
| 2016 Agosto | 8 | 1 | 9 |
| 2016 Julio | 22 | 2 | 24 |
| 2016 Junio | 22 | 21 | 43 |
| 2016 Mayo | 21 | 24 | 45 |
| 2016 Abril | 10 | 28 | 38 |
| 2016 Marzo | 21 | 21 | 42 |
| 2016 Febrero | 15 | 18 | 33 |
| 2016 Enero | 18 | 22 | 40 |
| 2015 Diciembre | 13 | 19 | 32 |
| 2015 Noviembre | 10 | 20 | 30 |
| 2015 Octubre | 23 | 21 | 44 |
| 2015 Septiembre | 17 | 8 | 25 |
| 2015 Agosto | 14 | 6 | 20 |
| 2015 Julio | 10 | 11 | 21 |
| 2015 Junio | 10 | 1 | 11 |
| 2015 Mayo | 9 | 10 | 19 |
| 2015 Abril | 9 | 14 | 23 |
| 2015 Marzo | 19 | 12 | 31 |
| 2015 Febrero | 7 | 3 | 10 |
| 2015 Enero | 12 | 5 | 17 |
| 2014 Diciembre | 9 | 12 | 21 |
| 2014 Noviembre | 6 | 7 | 13 |
| 2014 Octubre | 11 | 5 | 16 |
| 2014 Septiembre | 17 | 3 | 20 |
| 2014 Agosto | 12 | 6 | 18 |
| 2014 Julio | 13 | 3 | 16 |
| 2014 Junio | 6 | 2 | 8 |
| 2014 Mayo | 1 | 3 | 4 |
| 2014 Abril | 4 | 5 | 9 |
| 2014 Marzo | 3 | 1 | 4 |
| 2014 Febrero | 6 | 2 | 8 |
| 2014 Enero | 11 | 3 | 14 |
| 2013 Diciembre | 9 | 3 | 12 |
| 2013 Noviembre | 13 | 5 | 18 |
| 2013 Octubre | 6 | 15 | 21 |
| 2013 Septiembre | 10 | 14 | 24 |
| 2013 Agosto | 4 | 9 | 13 |
| 2013 Julio | 3 | 3 | 6 |
| 2009 Junio | 481 | 0 | 481 |
Mostrar todo
