Indicaciones de la bcg en los tumores superficiales de vejiga
J.L. Nogueira march1, A. Ojea calvo, B. Rodriguez iglesias, F. Dominguez freire, A. Rodriguez alonso, D. Perez garcia, A. Alonso rodriguez, J.M. Barros rodriguez, J. Benavente delgado
Servicio de Urología. Hospital Xeral de Vigo. Vigo
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"apellidos" => "Nogueira march" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Ojea calvo" ] 2 => array:2 [ "nombre" => "B." "apellidos" => "Rodriguez iglesias" ] 3 => array:2 [ "nombre" => "F." "apellidos" => "Dominguez freire" ] 4 => array:2 [ "nombre" => "A." "apellidos" => "Rodriguez alonso" ] 5 => array:2 [ "nombre" => "D." "apellidos" => "Perez garcia" ] 6 => array:2 [ "nombre" => "A." "apellidos" => "Alonso rodriguez" ] 7 => array:2 [ "nombre" => "J.M." "apellidos" => "Barros rodriguez" ] 8 => array:2 [ "nombre" => "J." "apellidos" => "Benavente delgado" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Servicio de Urología. Hospital Xeral de Vigo. Vigo" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "1" "correspondencia" => "Dr. J.L. Nogueira March Servicio de Urología. Hospital Xeral de Vigo C/ Pizarro, 22 36204 Vigo (Pontevedra)" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "1998-05-08" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec85674" "palabras" => array:5 [ 0 => "Tumor vesical superficial" 1 => "Inmunoterapia" 2 => "BCG" 3 => "Quimioterapia" 4 => "Mitomycina C" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec85673" "palabras" => array:5 [ 0 => "Surface tumour of the bladder" 1 => "Immunotherapy" 2 => "BCG" 3 => "Chemotherapy" 4 => "Mitomycin C" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Resumen</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">En esta visión global de la inmunoterapia con Bacilo de Calmette-Guerin (BCG) en la profilaxis y tratamiento del cáncer vesical superficial, se discuten una serie de aspectos, en parte de los cuales se ha alcanzado un consenso y otros en los que persiste la controversia. En relación con la elección de la mejor vía de administración, la instilación intravesical de BCG como única ruta, ha sido considerada la vía de administración más adecuada. En cuanto a la cepa de BCG a utilizar no se ha alcanzado consenso después del análisis de los datos suministrados por los estudios realizados. Respecto al esquema de tratamiento a seguir, parece evidente que el tratamiento de mantenimiento es superior al de inducción exclusivamente. No se ha alcanzado consenso en relación con al dosis óptima, ni en cuanto a la posibilidad de reducir la toxicidad. Aunque algunos estudios apoyan la creencia de que la inmunoterapia intravesical con BCG es superior a la quimioterapia, es necesario obtener nuevos datos que confirmen esta suposición. En conclusión, aunque el tratamiento con BCG ha demostrado su eficacia en los pacientes con tumores vesicales superficiales, no debe ser considerado como una panacea para utilizar indiscriminadamente en cualquier paciente portador de un tumor vesical superficial.</p>" ] "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Abstract</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Overall view of Bacille de Calmette-Guerin (BCG) immunotherapy in the prophylaxis and treatment of surface cancer of the bladder. A series of issues, on some of which a consensus has been reached while controversy is still frequent in others are discussed. Intravesical instillation of BCG as the single route has been considered to best mode of administration. With regard to the BCG strain to be used, there is still no consensus after the analysis of the data provided by the studies conducted. Relative to the treatment schedule, it appears clear that maintenance therapy is superior to an exclusively induction regime. No consensus has been reached about optimal dosage or the possibility to reduce toxicity. Although some studies support the belief that intravesical immunotherapy with BCG is superior to chemotherapy, further data is required to confirm such assumption. In conclusion, although treatment with BCG has proven to be effective in patients with surface tumours of the bladder, it should not be considered a panacea to be indiscriminately used in any patient with this malignancy.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Referencias" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:62 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." 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|---|---|---|---|
| 2099 Agosto | 357 | 0 | 357 |
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| 2024 Septiembre | 0 | 12 | 12 |
| 2024 Agosto | 0 | 9 | 9 |
| 2024 Julio | 0 | 2 | 2 |
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| 2024 Mayo | 0 | 6 | 6 |
| 2024 Abril | 0 | 12 | 12 |
| 2024 Marzo | 0 | 22 | 22 |
| 2024 Febrero | 0 | 14 | 14 |
| 2024 Enero | 0 | 6 | 6 |
| 2023 Diciembre | 0 | 23 | 23 |
| 2023 Noviembre | 0 | 49 | 49 |
| 2023 Octubre | 0 | 40 | 40 |
| 2023 Septiembre | 0 | 7 | 7 |
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| 2023 Mayo | 0 | 4 | 4 |
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| 2023 Marzo | 1 | 2 | 3 |
| 2023 Febrero | 0 | 3 | 3 |
| 2023 Enero | 0 | 5 | 5 |
| 2022 Diciembre | 0 | 3 | 3 |
| 2022 Noviembre | 0 | 7 | 7 |
| 2022 Octubre | 0 | 15 | 15 |
| 2022 Septiembre | 0 | 21 | 21 |
| 2022 Agosto | 0 | 20 | 20 |
| 2022 Julio | 0 | 8 | 8 |
| 2022 Junio | 0 | 13 | 13 |
| 2022 Mayo | 0 | 11 | 11 |
| 2022 Abril | 0 | 12 | 12 |
| 2022 Marzo | 0 | 19 | 19 |
| 2022 Febrero | 0 | 11 | 11 |
| 2022 Enero | 0 | 4 | 4 |
| 2021 Diciembre | 0 | 3 | 3 |
| 2021 Noviembre | 0 | 15 | 15 |
| 2021 Octubre | 0 | 11 | 11 |
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| 2021 Junio | 0 | 5 | 5 |
| 2021 Mayo | 0 | 7 | 7 |
| 2021 Abril | 0 | 39 | 39 |
| 2021 Marzo | 0 | 5 | 5 |
| 2021 Febrero | 0 | 4 | 4 |
| 2021 Enero | 0 | 8 | 8 |
| 2020 Diciembre | 0 | 22 | 22 |
| 2020 Noviembre | 0 | 50 | 50 |
| 2020 Octubre | 0 | 44 | 44 |
| 2020 Septiembre | 0 | 31 | 31 |
| 2020 Agosto | 0 | 33 | 33 |
| 2020 Julio | 0 | 19 | 19 |
| 2020 Junio | 0 | 21 | 21 |
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| 2020 Abril | 0 | 20 | 20 |
| 2020 Marzo | 0 | 25 | 25 |
| 2020 Febrero | 0 | 24 | 24 |
| 2020 Enero | 0 | 15 | 15 |
| 2019 Diciembre | 1 | 24 | 25 |
| 2019 Noviembre | 0 | 11 | 11 |
| 2019 Octubre | 0 | 19 | 19 |
| 2019 Septiembre | 0 | 14 | 14 |
| 2019 Agosto | 0 | 15 | 15 |
| 2019 Julio | 0 | 24 | 24 |
| 2019 Junio | 0 | 28 | 28 |
| 2019 Mayo | 0 | 54 | 54 |
| 2019 Abril | 0 | 5 | 5 |
| 2019 Marzo | 3 | 4 | 7 |
| 2018 Agosto | 0 | 1 | 1 |
| 2018 Febrero | 2 | 18 | 20 |
| 2018 Enero | 3 | 8 | 11 |
| 2017 Diciembre | 0 | 6 | 6 |
| 2017 Noviembre | 2 | 14 | 16 |
| 2017 Octubre | 6 | 19 | 25 |
| 2017 Septiembre | 7 | 11 | 18 |
| 2017 Agosto | 10 | 12 | 22 |
| 2017 Julio | 6 | 4 | 10 |
| 2017 Junio | 10 | 22 | 32 |
| 2017 Mayo | 9 | 10 | 19 |
| 2017 Abril | 7 | 44 | 51 |
| 2017 Marzo | 7 | 40 | 47 |
| 2017 Febrero | 23 | 13 | 36 |
| 2017 Enero | 13 | 5 | 18 |
| 2016 Diciembre | 28 | 9 | 37 |
| 2016 Noviembre | 26 | 17 | 43 |
| 2016 Octubre | 22 | 10 | 32 |
| 2016 Septiembre | 19 | 13 | 32 |
| 2016 Agosto | 20 | 17 | 37 |
| 2016 Julio | 10 | 9 | 19 |
| 2016 Junio | 11 | 21 | 32 |
| 2016 Mayo | 19 | 16 | 35 |
| 2016 Abril | 10 | 19 | 29 |
| 2016 Marzo | 15 | 22 | 37 |
| 2016 Febrero | 9 | 22 | 31 |
| 2016 Enero | 8 | 17 | 25 |
| 2015 Diciembre | 12 | 15 | 27 |
| 2015 Noviembre | 8 | 17 | 25 |
| 2015 Octubre | 16 | 19 | 35 |
| 2015 Septiembre | 10 | 9 | 19 |
| 2015 Agosto | 12 | 0 | 12 |
| 2015 Julio | 5 | 5 | 10 |
| 2015 Junio | 5 | 0 | 5 |
| 2015 Mayo | 5 | 4 | 9 |
| 2015 Abril | 7 | 4 | 11 |
| 2015 Marzo | 10 | 3 | 13 |
| 2015 Febrero | 4 | 1 | 5 |
| 2015 Enero | 8 | 2 | 10 |
| 2014 Diciembre | 17 | 4 | 21 |
| 2014 Noviembre | 10 | 3 | 13 |
| 2014 Octubre | 20 | 3 | 23 |
| 2014 Septiembre | 21 | 1 | 22 |
| 2014 Agosto | 16 | 3 | 19 |
| 2014 Julio | 19 | 2 | 21 |
| 2014 Junio | 20 | 2 | 22 |
| 2014 Mayo | 17 | 3 | 20 |
| 2014 Abril | 7 | 3 | 10 |
| 2014 Marzo | 11 | 0 | 11 |
| 2014 Febrero | 5 | 3 | 8 |
| 2014 Enero | 6 | 2 | 8 |
| 2013 Diciembre | 3 | 1 | 4 |
| 2013 Noviembre | 11 | 2 | 13 |
| 2013 Octubre | 5 | 5 | 10 |
| 2013 Septiembre | 12 | 7 | 19 |
| 2013 Agosto | 8 | 10 | 18 |
| 2013 Julio | 4 | 1 | 5 |
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