metricas
covid
Buscar en
Annals of Hepatology
Toda la web
Inicio Annals of Hepatology P-48 HEPATITIS DELTA: THE MOST SEVERE OF ALL VIRAL HEPATITIS
Información de la revista
Vol. 24. Núm. S1.
Abstracts of the 2021 Annual meeting of the ALEH (Asociación Latinoamericana para el Estudio del Hígado)
(septiembre 2021)
Compartir
Compartir
Descargar PDF
Más opciones de artículo
Vol. 24. Núm. S1.
Abstracts of the 2021 Annual meeting of the ALEH (Asociación Latinoamericana para el Estudio del Hígado)
(septiembre 2021)
Open Access
P-48 HEPATITIS DELTA: THE MOST SEVERE OF ALL VIRAL HEPATITIS
Visitas
537
Júlia Teixeira Ton1, Ester Teixeira Ton1, Alcione de Oliveira dos Santos2, Juan Miguel Villalobos Salcedo1,2, Deusilene Vieira Dallácqua1,2,3, Mariana Pinheiro Alves Vasconcelos2,4
1 Centro Universitário Aparício Carvalho – UNIFIMCA, Porto Velho, Rondônia
2 Centro de Pesquisa em Medicina Tropical de Rondônia – CEPEM, Porto Velho, Rondônia
3 Fundação Oswaldo Cruz de Rondônia – Fiocruz/Ro, Porto Velho, Rondônia
4 Centro de Medicina Tropical de Rondônia – Cemetron, Porto Velho, Rondônia
Este artículo ha recibido

Under a Creative Commons license
Información del artículo
Suplemento especial
Este artículo forma parte de:
Vol. 24. Núm S1

Abstracts of the 2021 Annual meeting of the ALEH (Asociación Latinoamericana para el Estudio del Hígado)

Más datos
Introduction

500,000 to 1.2 million deaths are speculated annually from complications of hepatitis B. The hepatitis Delta virus (HDV) also represents an important public health problem in endemic areas.

Objective

To analyze the clinical and laboratory characteristics at the first consultation of HBV and HBV/HDV patients.

Methods

Retrospective study (2017 and 2018) of 324 records of HBV and HBV/HDV patients at Research Center for Tropical Medicine of Rondônia. Project approved by the Research Ethics Committee. For statistical analysis, SPSS® version 25.0.

Results

A total of 324 patients were included, 302 (93.2%) were HBV and 22 were (6.7%) HBV/HDV. At the first consultation, 16.2% of the HBV showed signs of chronic liver disease, while in the HBV/HDV patients, 59.1% (p <0.0001). Signs of portal hypertension were present in 7.9% of HBV (splenomegaly in 5.6%) and in 54.5% of HBV/HDV patients (splenomegaly in 45.5%, p <0.0001). Ascites was seen in almost one third of those co-infected (27.3%). In laboratory analyzes, 6.4% of HBV patients had a total of bilirubin greater than 1.2 mg/dL, among those co-infected (45.5%, p <0.0001). Albumin was less than 3.5g/dL in 8.4% of the HBV and in 42.8% (p <0.0001) of the HBV/HDV patients. Alfafetoprotein was greater than 10UI/mL in 9.7% of the monoinfected and in 18.2% (p: 0.268) of the HBV/HDV patients.

Conclusion

Coinfected patients presented a more serious condition in the first consultation, with signs of portal hypertension and decompensated liver disease, reinforcing HDV as the most severe and rapidly progressive of all viral hepatitis.

El Texto completo está disponible en PDF
Descargar PDF
Opciones de artículo
es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos