Choroidal neovascularization secondary to choroideremia

Abstract

Case report

The case is presented of a 30-year-old man, with night blindness and decreased visual acuity (VA) in both eyes, but more significant in the left eye (LE) of 20/100. Lesions consistent with choroideremia and LE macular hemorrhage were observed in the fundus. CNV was confirmed by OCT. A definitive diagnosis was obtained by genetic study. No treatment was given as the patient did not return. At 6 months there was a regression of CNV with VA 20/25 in the LE.

Conclusions

CNV associated with choroideremia is uncommon. Treatment would antiangiogenic therapy, however spontaneous resolution is possible.

Resumen

Caso clínico

Varón de 30 años, con nictalopía y disminución de agudeza visual (AV) en ambos ojos, mayor en el ojo izquierdo (OI) de 20/100. En el fondo de ojo se observan lesiones compatibles con coroideremia y en OI, una hemorragia macular. Se confirma una NVC mediante OCT. El diagnóstico de certeza se obtuvo por estudio genético. No se realiza tratamiento porque el paciente no acude. A los 6 meses presenta regresión de la NVC con AV 20/25 en OI.

Conclusiones

La NVC asociada a coroideremia es infrecuente. El tratamiento sería la terapia antiangiogénica; sin embargo, es posible la resolución espontánea.