Estadísticas

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  "cita" => "Cir Esp. 1998;63:383-5"
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      "titulo" => "Metástasis pulmonares derivadas de tumores germinales"
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    "cita" => "Cir Esp. 1998;63:378-82"
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      "titulo" => "Carcinoma anaplásico de tiroides. Estado actual"
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          "autoresLista" => "F Villalba Ferrer, J Puche Pla, MJ García Coret, A Bordallo Cortina, MI Durán Bermejo, E Martí Cuñat, E de la Morena Valenzuela"
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    "titulo" => "Carcinoma mixto de mama con componente mucinoso y lobulillar infiltrante"
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        "titulo" => "Mixed lobular and mucinous carcinoma of the breast"
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          "identificador" => "xpalclavsec293857"
          "palabras" => array:5 [
            0 => "Mama"
            1 => "Tumor mixto"
            2 => "Bifásico"
            3 => "Lobulillar"
            4 => "Mucinoso"
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            2 => "Biphasic"
            3 => "Lobular"
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      "es" => array:1 [
        "resumen" => "Presentamos el caso de un tumor de mama en estadio avanzado (pT4) en una mujer de 63 años, con una zona superficial con características de carcinoma lobulillar infiltrante y una zona profunda de carcinoma mucinoso, con una transición gradual entre ambas. Este tipo de neoplasias mixtas o bifásicas son muy raras, con muy pocos casos descritos en la bibliografía. El tumor presenta positividad para queratinas de bajo peso en ambas zonas, bcl-2 más intenso en el área mucinosa y negatividad para queratinas de alto peso y enolasa. La evolución de la paciente fue mala, falleciendo a los 17 meses con extensas metástasis óseas. Se analiza el diagnóstico histológico y el estudio inmunohistoquímico, con especial atención al diagnóstico diferencial."
      ]
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        "resumen" => "The case is reported of a 63-year-old woman with an advanced breast tumor (pT4) presenting a superficial infiltrating lobular component with a gradual transition to a deep, mucinous carcinoma. Mixed or biphasic neoplasms of this type are very rare, with only a few cases described in the literature. Both regions of the lesion showed positivity for low molecular weight keratins and negativity for high molecular weight keratins and neuron-specific enolase&#59; bcl-2 expression was more intense in the mucinous area. The course of the disease was extremely poor and the patient died 17 months after diagnosis with extensive bone metastases. The histological diagnosis and immunohistochemical study are discussed, focusing especially on the differential diagnosis"
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