Morbimortalidad y supervivencia tras la paliación de la obstrucción maligna de la vía biliar
Morbidity, mortality and survival rates after palliative treatment of malignant bile duct obstruction
J.J. González1
, L. Sanz, E. Azcano, F. Navarrete, E. Martínez
Autor para correspondencia
jjglez@sci.cpd.uniovi.es
Correspondencia: Dr. E. Martínez Rodríguez. Julián Clavería, 6-6.°. 33006 Oviedo.
Correspondencia: Dr. E. Martínez Rodríguez. Julián Clavería, 6-6.°. 33006 Oviedo.
Servicio de Cirugía B. Hospital Central. Universidad de Oviedo. Oviedo
Leído
5843
Vecesse ha leído el artículo
1879
Total PDF
3964
Total HTML
Compartir estadísticas
array:23 [ "pii" => "S0009739X0171785X" "issn" => "0009739X" "doi" => "10.1016/S0009-739X(01)71785-X" "estado" => "S300" "fechaPublicacion" => "2001-05-01" "aid" => "71785" "copyright" => "Asociación Española de Cirujanos" "copyrightAnyo" => "2001" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Cir Esp. 2001;69:473-6" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 3154 "formatos" => array:3 [ "EPUB" => 6 "HTML" => 2673 "PDF" => 475 ] ] "itemSiguiente" => array:18 [ "pii" => "S0009739X01717861" "issn" => "0009739X" "doi" => "10.1016/S0009-739X(01)71786-1" "estado" => "S300" "fechaPublicacion" => "2001-05-01" "aid" => "71786" "copyright" => "Asociación Española de Cirujanos" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Cir Esp. 2001;69:477-81" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 3037 "formatos" => array:3 [ "EPUB" => 8 "HTML" => 2431 "PDF" => 598 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Problemas actuales de la formación en cirugía laparoscópica" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "477" "paginaFinal" => "481" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Current Problems of Training in Laparoscopic Surgery" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "J.R. Trullenque, E. Martí, T. Torres, J.M. Richart, S.A. Gómez" "autores" => array:6 [ 0 => array:2 [ "nombre" => "J.R." "apellidos" => "Trullenque" ] 1 => array:2 [ "nombre" => "E." "apellidos" => "Martí" ] 2 => array:2 [ "nombre" => "T." "apellidos" => "Torres" ] 3 => array:2 [ "nombre" => "J.M." "apellidos" => "Richart" ] 4 => array:2 [ "nombre" => "S.A." "apellidos" => "Gómez" ] 5 => array:2 [ "nombre" => "R." "apellidos" => "Trullenque" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0009739X01717861?idApp=UINPBA00004N" "url" => "/0009739X/0000006900000005/v1_201307101156/S0009739X01717861/v1_201307101156/es/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S0009739X01717848" "issn" => "0009739X" "doi" => "10.1016/S0009-739X(01)71784-8" "estado" => "S300" "fechaPublicacion" => "2001-05-01" "aid" => "71784" "copyright" => "Asociación Española de Cirujanos" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Cir Esp. 2001;69:467-72" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 24902 "formatos" => array:3 [ "EPUB" => 9 "HTML" => 19290 "PDF" => 5603 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Colecistectomía laparoscópica y sus complicaciones: nuestra experiencia en nueve años" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "467" "paginaFinal" => "472" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Laparoscopic Cholecystectomy and its Complications: A 9-Year Experience" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "J. Bueno, A. Serralta, M. Planells, S. Pous, C. Ballester, F. Ibáñez, D. Rodero" "autores" => array:7 [ 0 => array:2 [ "nombre" => "J." "apellidos" => "Bueno" ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Serralta" ] 2 => array:2 [ "nombre" => "M." "apellidos" => "Planells" ] 3 => array:2 [ "nombre" => "S." "apellidos" => "Pous" ] 4 => array:2 [ "nombre" => "C." "apellidos" => "Ballester" ] 5 => array:2 [ "nombre" => "F." "apellidos" => "Ibáñez" ] 6 => array:2 [ "nombre" => "D." "apellidos" => "Rodero" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0009739X01717848?idApp=UINPBA00004N" "url" => "/0009739X/0000006900000005/v1_201307101156/S0009739X01717848/v1_201307101156/es/main.assets" ] "es" => array:14 [ "idiomaDefecto" => true "titulo" => "Morbimortalidad y supervivencia tras la paliación de la obstrucción maligna de la vía biliar" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "473" "paginaFinal" => "476" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "J.J. González, L. Sanz, E. Azcano, F. Navarrete, E. Martínez" "autores" => array:5 [ 0 => array:4 [ "nombre" => "J.J." "apellidos" => "González" "email" => array:1 [ 0 => "jjglez@sci.cpd.uniovi.es" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "L." "apellidos" => "Sanz" ] 2 => array:2 [ "nombre" => "E." "apellidos" => "Azcano" ] 3 => array:2 [ "nombre" => "F." "apellidos" => "Navarrete" ] 4 => array:2 [ "nombre" => "E." "apellidos" => "Martínez" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Servicio de Cirugía B. Hospital Central. Universidad de Oviedo. Oviedo" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "1" "correspondencia" => "Correspondencia: Dr. E. Martínez Rodríguez. Julián Clavería, 6-6.°. 33006 Oviedo." ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Morbidity, mortality and survival rates after palliative treatment of malignant bile duct obstruction" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaAceptado" => "2000-12-31" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec197217" "palabras" => array:3 [ 0 => "Obstrucción de la vía biliar extrahepática" 1 => "Tratamiento paliativo" 2 => "Factores de riesgo" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec197218" "palabras" => array:3 [ 0 => "Extrahepatic bile duct obstruction" 1 => "Palliative treatment" 2 => "Risk factors" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Introducción</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">El desarrollo de nuevos procedimientos paliativos para el alivio de la obstrucción tumoral biliar exige el conocimiento de las distintas posibilidades de cada uno, la morbimortalidad asociada y la calidad de vida. El estudio de la supervivencia es la consecuencia lógica.</p> <span class="elsevierStyleSectionTitle">Pacientes y métodos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Estudio retrospectivo de 114 pacientes con compromiso tumoral del drenaje biliar extrahepático, no subsidiarios de resección, la mayoría, 99 (86,8%) con ictericia en el momento del diagnóstico. Predominaron los tumores del área periampular (62 [54,4%]) y, en consecuencia, las obstrucciones distales (63 [55,3%]). La paliación se llevó a cabo por medios quirúrgicos en 65 casos (57%) y radiológicos en 46 (40,4%). Se realizó un análisis univariante para discriminar variables con influencia sobre la morbimortalidad, y el cálculo de la supervivencia de los pacientes válidos para seguimiento.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">La estancia hospitalaria postratamiento fue similar en ambos grupos; 47 pacientes (41,2%) tuvieron complicaciones y 35 (30,7%) fallecieron, la mayoría por problemas relacionados con ictericia y sepsis. La morbilidad, variada, se agrupa en tres grandes apartados: hemorragia, sepsis y obstrucción de la prótesis/catéter. De las variables estudiadas sólo los valores de bilirrubina condicionaron la muerte de los pacientes. La mediana de la supervivencia fue de 7 meses y sólo el 7% vivían a los 2 años.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">La morbimortalidad es elevada, independiente del método de paliación empleado. Los valores de bilirrubina influyen en la posibilidad de muerte.</p>" ] "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Introduction</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Development of new palliative measures for relieving bile duct obstruction caused by malignant tumors is based on a good understanding of their scope in terms of the associated morbidity and mortality and quality of life. Hence the need to study the survival time of patients undergoing these palliative measures.</p> <span class="elsevierStyleSectionTitle">Material and methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">We performed a retrospective study of 114 patients with extrahepatic bile duct obstruction caused by non-resectable malignant tumor. Ninety-nine (86.8%) patients had jaundice at diagnosis. Sixty-two patients (54%) had periampullary tumors obstructing the distal part of the common bile duct. Sixty five patients (57%) underwent palliative surgery and 46 (40.4%) underwent radiotherapy. We performed a univariate analysis to identify the variables affecting morbidity and mortality and to calculate the survival time of the patients who could be followed up.</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Post-treatment hospital stay was similar in both groups. Forty seven (41.2%) patients developed complications, of whom 35 (30.7%) died, mainly as a result of jaundice and sepsis. The main complications were hemorrhage, sepsis, and obstruction of the prosthesis/catheter. Of the variables studied, only bilirubin level was positively correlated to fatal outcome. The median survival time was 7 months, and only 7% survived after 2 years.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Morbidity and mortality in the patients undergoing different palliative treatments for extrahepatic bile duct obstruction caused by a malignant tumour were high irrespective of the type of treatment. Bilirubin level was positively correlated to fatal outcome.</p>" ] ] "NotaPie" => array:1 [ 0 => array:1 [ "nota" => "<p class="elsevierStyleNotepara">Presentado en parte en el European Congress of IHPBA'97. Hamburgo, Alemania, en junio de 1997.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:34 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Endoscopic biliary endoprosthesis in the palliation of malignant obstruction of the distal common bile duct: a randomized trial" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "H.A. Shepherd" 1 => "G. Royle" 2 => "A.P.R. Ross" 3 => "A. Diba" 4 => "M. Arthur" 5 => "D. Colin-Jones" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Br J Surg" "fecha" => "1988" "volumen" => "75" "paginaInicial" => "1166" "paginaFinal" => "1168" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2466520" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Prospective controlled trial of transhepatic biliary endoprosthesis versus bypass surgery for incurable carcinoma of head of pancreas" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "P.C. Bornman" 1 => "E.P. Harries-Jones" 2 => "R. Tobias" 3 => "G. Van Stiegmann" 4 => "J. Terblanche" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Lancet" "fecha" => "1986" "volumen" => "1" "paginaInicial" => "69" "paginaFinal" => "71" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2432368" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Surgical treatment in proximal bile duct cancer. A single- center experience" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "R. Pichlmayr" 1 => "A. Weimann" 2 => "J. Klempnauer" 3 => "K.J. Oldhafer" 4 => "H. Maschek" 5 => "G. Tusch" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ann Surg" "fecha" => "1996" "volumen" => "224" "paginaInicial" => "628" "paginaFinal" => "638" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8916878" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Palliation. Surgical and otherwise" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "K.D. Lillemoe" 1 => "H.A. Pitt" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1002/(SICI)1097-0142(19960801)78:3<605::AID-CNCR41>3.0.CO;2-#" "Revista" => array:7 [ "tituloSerie" => "Cancer" "fecha" => "1996" "volumen" => "78" "numero" => "Supl 3" "paginaInicial" => "605" "paginaFinal" => "614" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8681299" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Malignant biliary obstruction: treatment with self-expandable steel endoprosthesis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "E.K. Salomonowitz" 1 => "A. Adam" 2 => "F. Antonucci" 3 => "G. Stuckmann" 4 => "C.L. Zollikofer" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Cardiovasc Intervent Radiol" "fecha" => "1992" "volumen" => "15" "paginaInicial" => "351" "paginaFinal" => "355" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1335839" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Paliación quirúrgica del carcinoma pancreático irresecable" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "K.D. Lillemoe" 1 => "S.A. Barnes" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Surg Clin North Am (esp" "fecha" => "1995" "volumen" => "75" "paginaInicial" => "925" "paginaFinal" => "939" ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0035" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effective palliation of malignant biliary tract obstruction" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "M.A. Malangoni" 1 => "D.M. McCoy" 2 => "J.D. Richardson" 3 => "L.M. Flint" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ann Surg" "fecha" => "1985" "volumen" => "201" "paginaInicial" => "554" "paginaFinal" => "559" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2581517" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0040" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pancreatic cancer: palliative endoscopic biliary drainage" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "B. Meduri" 1 => "J. Fritsch" 2 => "G. Calogero" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Int J Pancreatol" "fecha" => "1988" "volumen" => "3" "numero" => "Supl 1" "paginaInicial" => "S143" "paginaFinal" => "S146" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2463317" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0045" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Randomised trial of endoscopic endoprosthesis versus operative bypass in malignant obstructive jaundice" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J.R. Andersen" 1 => "S.M. Sorensen" 2 => "A. Kruse" 3 => "M. Rokkjaer" 4 => "P. Matzen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gut" "fecha" => "1989" "volumen" => "30" "paginaInicial" => "1132" "paginaFinal" => "1135" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2475392" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib0050" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Randomised trial of endoscopic stenting versus surgical by-pass in malignant low bile duct obstruction" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "A.C. Smith" 1 => "J.F. Dowsett" 2 => "R.C.G. Russell" 3 => "A.R.W. Hatfield" 4 => "P.B. Cotton" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Lancet" "fecha" => "1994" "volumen" => "344" "paginaInicial" => "1655" "paginaFinal" => "1660" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7996958" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib0055" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Morbidity and mortality after radical and palliative pancreatic cancer surgery. Risk factors influencing the short-term results" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "K.E. Bakkevold" 1 => "B. Kambestad" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ann Surg" "fecha" => "1993" "volumen" => "217" "paginaInicial" => "356" "paginaFinal" => "368" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7682052" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib0060" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Results of surgical palliation for cancer of the head of the pancreas and periampullary region" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "R. Pretre" 1 => "O. Huber" 2 => "J. Robert" 3 => "C. Soravia" 4 => "R.A. Egeli" 5 => "A. Roher" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Br J Surg" "fecha" => "1992" "volumen" => "79" "paginaInicial" => "795" "paginaFinal" => "798" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1382797" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib0065" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Hemorrhage after pancreatoduodenectomy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "B. Rumstadt" 1 => "M. Schwab" 2 => "P. Korth" 3 => "M. Samman" 4 => "M. Trede" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ann Surg" "fecha" => "1998" "volumen" => "227" "paginaInicial" => "236" "paginaFinal" => "241" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9488522" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib0070" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Perioperative management of obstructive jaundice" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "T. Diamond" 1 => "R.W. Parks" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Br J Surg" "fecha" => "1997" "volumen" => "84" "paginaInicial" => "147" "paginaFinal" => "149" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9052423" "web" => "Medline" ] ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib0075" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Renal dysfunction in obstructive jaundice" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "B.J. Fogarty" 1 => "R.W. Parks" 2 => "B.J. Rowlands" 3 => "T. Diamond" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Br J Surg" "fecha" => "1995" "volumen" => "82" "paginaInicial" => "877" "paginaFinal" => "884" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7648096" "web" => "Medline" ] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib0080" "etiqueta" => "16." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Endoscopic stenting for palliation of malignant biliary obstruction. A review of progress in the last 15 years" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "J.J.Y. Sung" 1 => "S.C.S. Chung" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Dig Dis Sci" "fecha" => "1995" "volumen" => "40" "paginaInicial" => "1167" "paginaFinal" => "1173" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7540126" "web" => "Medline" ] ] ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib0085" "etiqueta" => "17." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Endoscopic biliary stenting for the palliation of pancreatic cancer: results, survival predictive factors, and comparison of 10-French with 11,5-French gauge stents" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "J.C. Pereira-Lima" 1 => "R. Jakobs" 2 => "M. Maier" 3 => "C. Benz" 4 => "B. Kohler" 5 => "J.F. Riemann" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Gastroenterol" "fecha" => "1996" "volumen" => "91" "paginaInicial" => "2179" "paginaFinal" => "2184" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8855744" "web" => "Medline" ] ] ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib0090" "etiqueta" => "18." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bacteria involved in the blockage of biliary stents and their susceptibility to antibacterial agents" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "G. Molinari" 1 => "V. Pugliese" 2 => "G.C. Schito" 3 => "C.A. Guzman" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur J Clin Microbiol Infect Dis" "fecha" => "1996" "volumen" => "15" "paginaInicial" => "88" "paginaFinal" => "92" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8641313" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib0095" "etiqueta" => "19." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Paliación de la ictericia obstructiva maligna mediante drenaje biliar y prótesis metálicas. Análisis de nuestra experiencia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "M.D. Ferrer" 1 => "J. Calvete" 2 => "M.S. Laso" 3 => "J. Gil" 4 => "E. Nogués" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Cir Esp" "fecha" => "1997" "volumen" => "62" "paginaInicial" => "466" "paginaFinal" => "470" ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib0100" "etiqueta" => "20." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Randomised trial of self-expanding metal stents for distal malignant biliary obstruction" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "P.H.P. Davids" 1 => "A.K. Groen" 2 => "E.A.J. Rauws" 3 => "G.N.J. Tytgat" 4 => "K. Huibregtse" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Lancet" "fecha" => "1992" "volumen" => "340" "paginaInicial" => "1482" "paginaFinal" => "1492" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1360609" "web" => "Medline" ] ] ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib0105" "etiqueta" => "21." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Metallic stents in malignant biliary obstruction: prospective long-term clinical results" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "B.H. Lee" 1 => "D.H. Choe" 2 => "J.H. Lee" 3 => "K.H. Kim" 4 => "S.Y. Chin" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.2214/ajr.168.3.9057527" "Revista" => array:6 [ "tituloSerie" => "AJR" "fecha" => "1997" "volumen" => "168" "paginaInicial" => "741" "paginaFinal" => "745" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9057527" "web" => "Medline" ] ] ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib0110" "etiqueta" => "22." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Endoprótesis antoexpandibles en el tratamiento de la vía biliar obstruida" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "J. Palmero da Cruz" 1 => "M.D. Ferrer Puchol" 2 => "J. Martínez Rodrigo" 3 => "F. Blanes Masson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Cir Esp" "fecha" => "1994" "volumen" => "56" "paginaInicial" => "357" "paginaFinal" => "362" ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bib0115" "etiqueta" => "23." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Metallic stents in malignant biliary obstruction: results of a multicenter European study of 240 patients" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "P. Rossi" 1 => "M. Bezzi" 2 => "M. Rossi" 3 => "A. Adam" 4 => "N. Chetty" 5 => "M.E. Roddie" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Vasc Interv Radiol" "fecha" => "1994" "volumen" => "5" "paginaInicial" => "279" "paginaFinal" => "285" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7514463" "web" => "Medline" ] ] ] ] ] ] ] ] 23 => array:3 [ "identificador" => "bib0120" "etiqueta" => "24." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ictericia obstructiva neoplásica. Tratamiento paliativo con prótesis metálica autoexpandible" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A. Aldeano" 1 => "C. Sanz" 2 => "J. Figueras" 3 => "J. Domínguez" 4 => "C. Sancho" 5 => "L. Fernández Cabrera" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Rev esp enferm dig" "fecha" => "1995" "volumen" => "87" "paginaInicial" => "625" "paginaFinal" => "631" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7577120" "web" => "Medline" ] ] ] ] ] ] ] ] 24 => array:3 [ "identificador" => "bib0125" "etiqueta" => "25." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Paliación percutánea del cáncer pancreático irresecable" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "S.L. Kaufman" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Surg Clin North Am (ed. esp.)" "fecha" => "1995" "volumen" => "75" "paginaInicial" => "961" "paginaFinal" => "971" ] ] ] ] ] ] 25 => array:3 [ "identificador" => "bib0130" "etiqueta" => "26." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Guidelines for the application of surgery and endoprosthesis in the palliation of obstructive jaundice in advanced cancer of the pancreas" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "R.P. Van den Bosch" 1 => "G.P. Van der Schelling" 2 => "J.H.G. Klin-Kenbijl" 3 => "P.G.H. Mulder" 4 => "M. Van Blankenstein" 5 => "J. Jeekel" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ann Surg" "fecha" => "1994" "volumen" => "219" "paginaInicial" => "18" "paginaFinal" => "24" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7507656" "web" => "Medline" ] ] ] ] ] ] ] ] 26 => array:3 [ "identificador" => "bib0135" "etiqueta" => "27." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Surgical biliary bypass for benign and malignant extrahepatic biliary tract disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "R.W. Parks" 1 => "G.W. Johnston" 2 => "B.J. Rowlands" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Br J Surg" "fecha" => "1997" "volumen" => "4" "paginaInicial" => "488" "paginaFinal" => "492" ] ] ] ] ] ] 27 => array:3 [ "identificador" => "bib0140" "etiqueta" => "28." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Is there a place for gastroenterostomy in patients with advanced cancer of the head of the pancreas?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "G.P. Van der Schelling" 1 => "R.P. Van den Bosch" 2 => "J.H.G. Klinkenbij" 3 => "P.G.H. Mulder" 4 => "J. Jeekel" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "World J surg" "fecha" => "1993" "volumen" => "17" "paginaInicial" => "128" "paginaFinal" => "133" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7680512" "web" => "Medline" ] ] ] ] ] ] ] ] 28 => array:3 [ "identificador" => "bib0145" "etiqueta" => "29." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Laparoscopic gastrojejunostomy and endocopic biliary stent placement for palliation of incurable gastric outlet obstruction with cholestasis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "I.B. Brune" 1 => "H. Feussner" 2 => "H. Neuhaus" 3 => "M. Classen" 4 => "J.R. Siewert" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Surg endosc" "fecha" => "1997" "volumen" => "11" "paginaInicial" => "834" "paginaFinal" => "837" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9266646" "web" => "Medline" ] ] ] ] ] ] ] ] 29 => array:3 [ "identificador" => "bib0150" "etiqueta" => "30." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Surgical palliation for pancreatic cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "P. Watanapa" 1 => "R.C.N. Williamson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Br J Surg" "fecha" => "1992" "volumen" => "79" "paginaInicial" => "8" "paginaFinal" => "20" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1371087" "web" => "Medline" ] ] ] ] ] ] ] ] 30 => array:3 [ "identificador" => "bib0155" "etiqueta" => "31." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Biliary Wallstent endoprosthesis in malignant hilar obstruction: long-term results with regard to the type of obstruction" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "W. Shima" 1 => "R. Prokesch" 2 => "C. Osterreicher" 3 => "S. Thurnher" 4 => "R. Függer" 5 => "R. Schöfl" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Radiol" "fecha" => "1997" "volumen" => "52" "paginaInicial" => "213" "paginaFinal" => "219" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9091256" "web" => "Medline" ] ] ] ] ] ] ] ] 31 => array:3 [ "identificador" => "bib0160" "etiqueta" => "32." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Obstructive jaundice promotes bacterial translocation from the gut" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "E.A. Deitch" 1 => "K. Sittig" 2 => "M. Li" 3 => "R. Berg" 4 => "R.D. Specian" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Surg" "fecha" => "1990" "volumen" => "159" "paginaInicial" => "79" "paginaFinal" => "84" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2136788" "web" => "Medline" ] ] ] ] ] ] ] ] 32 => array:3 [ "identificador" => "bib0165" "etiqueta" => "33." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Factors affecting morbidity and mortality after surgery for obstructive jaundice: a review of 373 patients" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "J.M. Dixon" 1 => "C.P. Armstrong" 2 => "S.W. Duffy" 3 => "G.C. Davies" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gut" "fecha" => "1983" "volumen" => "24" "paginaInicial" => "845" "paginaFinal" => "852" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6604001" "web" => "Medline" ] ] ] ] ] ] ] ] 33 => array:3 [ "identificador" => "bib0170" "etiqueta" => "34." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Does preoperative percutaneous biliary drainage reduce operative risk or increase hospital cost?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "H.A. Pitt" 1 => "A.S. Gomes" 2 => "J.F. Lois" 3 => "L.L. Mann" 4 => "L.S. Deutsch" 5 => "W.P. Longmire Jr." ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ann Surg" "fecha" => "1985" "volumen" => "201" "paginaInicial" => "545" "paginaFinal" => "553" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2986562" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "es" "url" => "/0009739X/0000006900000005/v1_201307101156/S0009739X0171785X/v1_201307101156/es/main.assets" "Apartado" => array:4 [ "identificador" => "5768" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Originales" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/0009739X/0000006900000005/v1_201307101156/S0009739X0171785X/v1_201307101156/es/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0009739X0171785X?idApp=UINPBA00004N" ]
| año/Mes | Html | Total | |
|---|---|---|---|
| 2024 Octubre | 4 | 28 | 32 |
| 2024 Septiembre | 16 | 63 | 79 |
| 2024 Agosto | 12 | 54 | 66 |
| 2024 Julio | 16 | 54 | 70 |
| 2024 Junio | 11 | 62 | 73 |
| 2024 Mayo | 11 | 50 | 61 |
| 2024 Abril | 21 | 43 | 64 |
| 2024 Marzo | 28 | 65 | 93 |
| 2024 Febrero | 28 | 62 | 90 |
| 2024 Enero | 20 | 54 | 74 |
| 2023 Diciembre | 32 | 86 | 118 |
| 2023 Noviembre | 30 | 73 | 103 |
| 2023 Octubre | 34 | 47 | 81 |
| 2023 Septiembre | 25 | 40 | 65 |
| 2023 Agosto | 20 | 30 | 50 |
| 2023 Julio | 32 | 36 | 68 |
| 2023 Junio | 17 | 6 | 23 |
| 2023 Mayo | 39 | 18 | 57 |
| 2023 Abril | 20 | 9 | 29 |
| 2023 Marzo | 5 | 7 | 12 |
| 2023 Febrero | 15 | 22 | 37 |
| 2023 Enero | 12 | 8 | 20 |
| 2022 Diciembre | 22 | 8 | 30 |
| 2022 Noviembre | 68 | 21 | 89 |
| 2022 Octubre | 26 | 22 | 48 |
| 2022 Septiembre | 17 | 17 | 34 |
| 2022 Agosto | 61 | 35 | 96 |
| 2022 Julio | 42 | 10 | 52 |
| 2022 Junio | 33 | 9 | 42 |
| 2022 Mayo | 20 | 18 | 38 |
| 2022 Abril | 40 | 20 | 60 |
| 2022 Marzo | 19 | 12 | 31 |
| 2022 Febrero | 24 | 4 | 28 |
| 2022 Enero | 25 | 10 | 35 |
| 2021 Diciembre | 10 | 16 | 26 |
| 2021 Noviembre | 30 | 13 | 43 |
| 2021 Octubre | 50 | 9 | 59 |
| 2021 Septiembre | 21 | 7 | 28 |
| 2021 Agosto | 11 | 3 | 14 |
| 2021 Julio | 19 | 23 | 42 |
| 2021 Junio | 14 | 7 | 21 |
| 2021 Mayo | 24 | 10 | 34 |
| 2021 Abril | 34 | 9 | 43 |
| 2021 Marzo | 27 | 11 | 38 |
| 2021 Febrero | 26 | 11 | 37 |
| 2021 Enero | 14 | 14 | 28 |
| 2020 Diciembre | 10 | 11 | 21 |
| 2020 Noviembre | 9 | 2 | 11 |
| 2020 Octubre | 30 | 13 | 43 |
| 2020 Septiembre | 21 | 29 | 50 |
| 2020 Agosto | 17 | 40 | 57 |
| 2020 Julio | 14 | 6 | 20 |
| 2020 Junio | 8 | 1 | 9 |
| 2020 Mayo | 18 | 18 | 36 |
| 2020 Abril | 17 | 12 | 29 |
| 2020 Marzo | 17 | 21 | 38 |
| 2020 Febrero | 13 | 24 | 37 |
| 2020 Enero | 14 | 21 | 35 |
| 2019 Diciembre | 25 | 15 | 40 |
| 2019 Noviembre | 10 | 5 | 15 |
| 2019 Octubre | 6 | 9 | 15 |
| 2019 Septiembre | 15 | 5 | 20 |
| 2019 Agosto | 12 | 17 | 29 |
| 2019 Julio | 7 | 10 | 17 |
| 2019 Junio | 22 | 16 | 38 |
| 2019 Mayo | 105 | 109 | 214 |
| 2019 Abril | 30 | 14 | 44 |
| 2019 Marzo | 2 | 1 | 3 |
| 2019 Febrero | 8 | 5 | 13 |
| 2019 Enero | 3 | 8 | 11 |
| 2018 Diciembre | 5 | 7 | 12 |
| 2018 Noviembre | 7 | 10 | 17 |
| 2018 Octubre | 17 | 19 | 36 |
| 2018 Septiembre | 7 | 3 | 10 |
| 2018 Agosto | 1 | 0 | 1 |
| 2018 Julio | 4 | 4 | 8 |
| 2018 Junio | 1 | 1 | 2 |
| 2018 Mayo | 2 | 1 | 3 |
| 2018 Abril | 3 | 1 | 4 |
| 2018 Marzo | 4 | 1 | 5 |
| 2018 Febrero | 6 | 0 | 6 |
| 2018 Enero | 8 | 1 | 9 |
| 2017 Diciembre | 6 | 2 | 8 |
| 2017 Noviembre | 8 | 2 | 10 |
| 2017 Octubre | 9 | 2 | 11 |
| 2017 Septiembre | 13 | 6 | 19 |
| 2017 Agosto | 4 | 0 | 4 |
| 2017 Julio | 8 | 1 | 9 |
| 2017 Junio | 10 | 1 | 11 |
| 2017 Mayo | 7 | 1 | 8 |
| 2017 Abril | 9 | 1 | 10 |
| 2017 Marzo | 6 | 2 | 8 |
| 2017 Febrero | 13 | 0 | 13 |
| 2017 Enero | 11 | 0 | 11 |
| 2016 Diciembre | 21 | 4 | 25 |
| 2016 Noviembre | 28 | 3 | 31 |
| 2016 Octubre | 47 | 0 | 47 |
| 2016 Septiembre | 16 | 3 | 19 |
| 2016 Agosto | 8 | 1 | 9 |
| 2016 Julio | 22 | 1 | 23 |
| 2016 Junio | 31 | 11 | 42 |
| 2016 Mayo | 37 | 6 | 43 |
| 2016 Abril | 21 | 3 | 24 |
| 2016 Marzo | 38 | 12 | 50 |
| 2016 Febrero | 34 | 12 | 46 |
| 2016 Enero | 27 | 11 | 38 |
| 2015 Diciembre | 25 | 13 | 38 |
| 2015 Noviembre | 18 | 1 | 19 |
| 2015 Octubre | 24 | 7 | 31 |
| 2015 Septiembre | 25 | 6 | 31 |
| 2015 Agosto | 22 | 1 | 23 |
| 2015 Julio | 13 | 6 | 19 |
| 2015 Junio | 6 | 1 | 7 |
| 2015 Mayo | 15 | 2 | 17 |
| 2015 Abril | 12 | 10 | 22 |
| 2015 Marzo | 13 | 3 | 16 |
| 2015 Febrero | 29 | 4 | 33 |
| 2015 Enero | 41 | 5 | 46 |
| 2014 Diciembre | 50 | 7 | 57 |
| 2014 Noviembre | 33 | 2 | 35 |
| 2014 Octubre | 35 | 2 | 37 |
| 2014 Septiembre | 28 | 1 | 29 |
| 2014 Agosto | 42 | 1 | 43 |
| 2014 Julio | 31 | 4 | 35 |
| 2014 Junio | 36 | 1 | 37 |
| 2014 Mayo | 22 | 2 | 24 |
| 2014 Abril | 26 | 1 | 27 |
| 2014 Marzo | 26 | 3 | 29 |
| 2014 Febrero | 18 | 2 | 20 |
| 2014 Enero | 15 | 3 | 18 |
| 2013 Diciembre | 14 | 2 | 16 |
| 2013 Noviembre | 17 | 2 | 19 |
| 2013 Octubre | 21 | 1 | 22 |
| 2013 Septiembre | 17 | 3 | 20 |
| 2013 Agosto | 15 | 2 | 17 |
| 2013 Julio | 5 | 0 | 5 |
| 2001 Abril | 1213 | 0 | 1213 |
Mostrar todo
