Resultados. La isquemia de 45 min produce un descenso del flujo tisular hepático, en la primera hora de reperfusión, hasta del 35,48 y del 39,93% en los grupos con y sin resección asociada, respectivamente, sin diferencias entre ellos.
Conclusiones. La isquemia hepática de 45 min presenta diferencias en el flujo de la microcirculación posreperfusión, independientemente de haberse resecado o no el equivalente a un 40% del hígado.
Material and method. Four groups of eight rats each were used: a control group that was not subjected to prolonged ischemia; a control group that underwent resection of left liver lobe; a group subjected to 45 minutes of ischemia; and a group that underwent both a 45-minute period of ischemia and resection of left liver lobe. The effect on the microcirculation was assessed by means of laser-Doppler flowmetry and histological study.
Results. The 45-minute period of ischemia reduced the blood flow in the liver tissue during the first hour of reperfusion by as much as 35.48% and 39.43% in the groups with and without associated resection, respectively, rates that did not differ significantly from one to the other.
Conclusions.. The 45-minute period of liver ischemia changes postreperfusion blood flow through the hepatic microcirculation regardless of whether or not 40% of the liver has been resected.