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Inicio Cirugía Española (English Edition) Microorganisms and cancer: Scientific evidence and new hypotheses
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Vol. 89. Núm. 3.
Páginas 136-144 (marzo 2011)
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Vol. 89. Núm. 3.
Páginas 136-144 (marzo 2011)
Acceso a texto completo
Microorganisms and cancer: Scientific evidence and new hypotheses
Microorganismos y cáncer: evidencias científicas y nuevas hipótesis
Visitas
2046
Encarna Velázqueza, Álvaro Peixb, Alberto Gómez-Alonsoc,
Autor para correspondencia
agam@usal.es

Corresponding author.
a Departamento de Microbiología y Genética, Universidad de Salamanca, Salamanca, Spain
b IRNASA-CSIC, Salamanca, Spain
c Departamento de Cirugía, Universidad de Salamanca, Salamanca, Spain
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Información del artículo
Abstract

Microorganism involvement in cancer has been known for over a century, and different types of parasites, bacteria and viruses have been associated with oncogenic processes. Among the bacteria, the first recognised was Helicobacter pylori which causes gastric cancer and might be related to extra-gastric cancer in humans. Helicobacter hepaticus has been associated with liver cancers using animal models. Other bacteria such as, Chlamydia psitacii, Borrelia burgdorferi and Streptococcus bovis have been associated with ocular, skin and colorectal cancers, respectively. Also, a commensal bacterium in the human intestine, Bacteroides fragilis, has been linked, very recently, with colorectal cancer using animal models.

Keywords:
Cancer
Microorganisms
Humans
Resumen

La implicación de los microorganismos en el cáncer humano se conoce desde hace más de un siglo y diferentes tipos de parásitos, bacterias y virus se han relacionado con procesos oncogénicos. Dentro de las bacterias, la primera reconocida como carcinogénica fue Helicobacter pylori, que causa cáncer gástrico y podría estar relacionada con cánceres extragástricos en el hombre. Helicobacter hepaticus se ha relacionado con cánceres hepáticos utilizando modelos animales. Otras bacterias, como Chlamydia psitacii, Borrelia burgdorferi y Streptococcus bovis, se han relacionado con cánceres oculares, de piel y colorrectal, respectivamente. Además, una bacteria comensal del intestino humano, Bacteroides fragilis, se ha vinculado muy recientemente con el cáncer colorrectal utilizando modelos animales.

Palabras clave:
Cáncer
Microorganismos
Hombre
El Texto completo está disponible en PDF
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