Estadísticas

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      "titulo" => "Cardiotoxicidad de terapias moleculares blanco"
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    "titulo" => "Estrategias de cardioprotección&#59; ¿mantienen la efectividad de la quimioterapia?"
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        "resumen" => "Las antraciclinas son un grupo de f&#225;rmacos antitumorales que han mostrado su eficacia en distintas neoplasias&#59; sin embargo&#44; su utilizaci&#243;n se limita por sus efectos t&#243;xicos asociados&#44; principalmente la cardiotoxicidad&#44; la cual disminuye la calidad de vida y aumenta el &#237;ndice de muertes prematuras por causas cardiovasculares en ni&#241;os y adultos&#46; Se han estudiado varias estrategias dirigidas a reducir la frecuencia de cardiotoxicidad relacionada con las antraciclinas &#40;infusi&#243;n prolongada&#44; sustituci&#243;n de f&#225;rmacos o dexrazoxane&#41;&#44; que han confirmado su capacidad cardioprotectora&#46; Sin embargo&#44; existe preocupaci&#243;n por la posibilidad de reducir el potencial terap&#233;utico de la quimioterapia con estas estrategias de cardioprotecci&#243;n&#46; En este trabajo se analiza la eficacia terap&#233;utica de la quimioterapia en relaci&#243;n con cada una de las estrategias cardioprotectoras ensayadas en estudios comparativos&#46;"
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