Regresión espontánea de carcinoma hepatocelular en paciente cirrótico
Spontaneous Regression Of Hepatocellular Carcinoma In A Cirrhotic Patient
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"apellidos" => "Garrido Serrano" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "*" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "F.J." "apellidos" => "Guerrero Igea" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "J.A." "apellidos" => "Lepe Jiménez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] ] 3 => array:3 [ "nombre" => "S." "apellidos" => "Palomo Gil" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Unidad de Digestivo Hospital Comarcal de Riotinto. Huelva" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Medicina Interna Hospital Comarcal de Riotinto. Huelva" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Sección de Microbiología. Hospital Comarcal de Riotinto. Huelva" "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "*" "correspondencia" => "Correspondencia: Dr. A. Garrido Serrano. Almajarra, 1, bloque 7, 1.° B. Urbanización Jardines de Sta. Eufemia. 41940 Tomares. Sevilla." ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Spontaneous Regression Of Hepatocellular Carcinoma In A Cirrhotic Patient" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2001-06-12" "fechaAceptado" => "2001-09-03" "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Resumen</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">El carcinoma hepatocelular afecta principalmente a pacientes con enfermedad hepática, y su aparición en un hígado sano es muy rara. La cirrosis confiere un riesgo mucho más elevado, por lo que estos pacientes son candidatos a programas de seguimiento y vigilancia. Las pruebas de cribado más comúnmente usadas son la ecografía abdominal y la determinación de alfa-fetoproteína sérica.</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">El pronóstico del carcinoma hepatocelular no tratado es generalmente grave, incluso pequeños tumores detectados en programas de seguimiento siguen teniendo una mortalidad significativa.</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Presentamos el caso de un paciente varón de 71 años de edad, portador de una cirrosis de origen etílico y que fue diagnosticado durante su seguimiento de CHC único de 4 cm de diámetro, negándose a todo tratamiento, a pesar de lo cual evolucionó favorablemente con normalización de los valores de alfa-fetoproteína sérica y desaparición de la imagen ecográfica compatible con carcinoma hepatocelular, encontrándose asintomático por completo 3 años después de su diagnóstico.</p>" ] "en" => array:1 [ "resumen" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Hepatocellular carcinoma mainly affects patients with liver disease and rarely develops in healthy liver. Cirrhosis greatly increases the risk of developing this malignancy and consequently these patients are candidates for close followup and surveillance. The most commonly used screening programs are abdominal ultrasonography and serum alphafetoprotein determination.</p><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">:Without treatment, the prognosis of hepatocellular carcinoma is poor and mortality continues to be significant even in patients with small tumors detected during follow-up. We present the case of a 71-year-old male patient with alcoholic cirrhosis. The patient was diagnosed during follow-up of a single hepatocellular carcinoma of 4 cm in diameter. Although he refused all treatment, evolution was favorable, serum alpha-fetoprotein levels returned to normal and ultrasonographic images compatible with hepatocellular carcinoma disappeared. Three years after diagnosis, the patient was completely asymptomatic.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Biblografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:16 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Tumores hepáticos" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "J. Bruix" 1 => "C. Bru" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Medicine" "fecha" => "1992" "volumen" => "6" "paginaInicial" => "367" "paginaFinal" => "374" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Hepatocellular carcinoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "A.M. 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| 2024 Enero | 12 | 4 | 16 |
| 2023 Diciembre | 16 | 11 | 27 |
| 2023 Noviembre | 12 | 34 | 46 |
| 2023 Octubre | 23 | 19 | 42 |
| 2023 Septiembre | 15 | 12 | 27 |
| 2023 Agosto | 10 | 7 | 17 |
| 2023 Julio | 9 | 12 | 21 |
| 2023 Junio | 3 | 7 | 10 |
| 2023 Mayo | 12 | 11 | 23 |
| 2023 Abril | 4 | 2 | 6 |
| 2023 Marzo | 6 | 1 | 7 |
| 2023 Febrero | 8 | 11 | 19 |
| 2023 Enero | 9 | 5 | 14 |
| 2022 Diciembre | 13 | 3 | 16 |
| 2022 Noviembre | 23 | 7 | 30 |
| 2022 Octubre | 21 | 17 | 38 |
| 2022 Septiembre | 16 | 16 | 32 |
| 2022 Agosto | 15 | 17 | 32 |
| 2022 Julio | 10 | 12 | 22 |
| 2022 Junio | 10 | 6 | 16 |
| 2022 Mayo | 9 | 8 | 17 |
| 2022 Abril | 20 | 22 | 42 |
| 2022 Marzo | 11 | 15 | 26 |
| 2022 Febrero | 17 | 9 | 26 |
| 2022 Enero | 5 | 6 | 11 |
| 2021 Diciembre | 6 | 11 | 17 |
| 2021 Noviembre | 11 | 4 | 15 |
| 2021 Octubre | 7 | 11 | 18 |
| 2021 Septiembre | 7 | 13 | 20 |
| 2021 Agosto | 7 | 7 | 14 |
| 2021 Julio | 11 | 6 | 17 |
| 2021 Junio | 7 | 13 | 20 |
| 2021 Mayo | 11 | 8 | 19 |
| 2021 Abril | 21 | 10 | 31 |
| 2021 Marzo | 18 | 13 | 31 |
| 2021 Febrero | 8 | 9 | 17 |
| 2021 Enero | 11 | 12 | 23 |
| 2020 Diciembre | 8 | 5 | 13 |
| 2020 Noviembre | 4 | 4 | 8 |
| 2020 Octubre | 5 | 6 | 11 |
| 2020 Septiembre | 9 | 9 | 18 |
| 2020 Agosto | 9 | 15 | 24 |
| 2020 Julio | 8 | 13 | 21 |
| 2020 Junio | 2 | 4 | 6 |
| 2020 Mayo | 5 | 7 | 12 |
| 2020 Abril | 1 | 4 | 5 |
| 2020 Marzo | 4 | 6 | 10 |
| 2020 Febrero | 4 | 5 | 9 |
| 2020 Enero | 5 | 8 | 13 |
| 2019 Diciembre | 22 | 22 | 44 |
| 2019 Noviembre | 6 | 4 | 10 |
| 2019 Octubre | 4 | 12 | 16 |
| 2019 Septiembre | 5 | 4 | 9 |
| 2019 Agosto | 1 | 11 | 12 |
| 2019 Julio | 9 | 14 | 23 |
| 2019 Junio | 18 | 55 | 73 |
| 2019 Mayo | 38 | 63 | 101 |
| 2019 Abril | 18 | 21 | 39 |
| 2019 Marzo | 5 | 5 | 10 |
| 2019 Febrero | 8 | 11 | 19 |
| 2019 Enero | 3 | 5 | 8 |
| 2018 Diciembre | 4 | 6 | 10 |
| 2018 Noviembre | 12 | 18 | 30 |
| 2018 Octubre | 11 | 11 | 22 |
| 2018 Septiembre | 5 | 2 | 7 |
| 2018 Agosto | 7 | 3 | 10 |
| 2018 Julio | 6 | 3 | 9 |
| 2018 Junio | 5 | 6 | 11 |
| 2018 Mayo | 1 | 7 | 8 |
| 2018 Abril | 4 | 4 | 8 |
| 2018 Marzo | 5 | 3 | 8 |
| 2018 Febrero | 5 | 5 | 10 |
| 2018 Enero | 0 | 2 | 2 |
| 2017 Diciembre | 4 | 4 | 8 |
| 2017 Noviembre | 3 | 4 | 7 |
| 2017 Octubre | 8 | 3 | 11 |
| 2017 Septiembre | 6 | 7 | 13 |
| 2017 Agosto | 4 | 5 | 9 |
| 2017 Julio | 3 | 3 | 6 |
| 2017 Junio | 6 | 18 | 24 |
| 2017 Mayo | 4 | 2 | 6 |
| 2017 Abril | 10 | 4 | 14 |
| 2017 Marzo | 20 | 35 | 55 |
| 2017 Febrero | 12 | 4 | 16 |
| 2017 Enero | 8 | 0 | 8 |
| 2016 Diciembre | 18 | 2 | 20 |
| 2016 Noviembre | 17 | 3 | 20 |
| 2016 Octubre | 24 | 14 | 38 |
| 2016 Septiembre | 13 | 4 | 17 |
| 2016 Agosto | 7 | 2 | 9 |
| 2016 Julio | 13 | 2 | 15 |
| 2016 Junio | 21 | 10 | 31 |
| 2016 Mayo | 14 | 9 | 23 |
| 2016 Abril | 13 | 6 | 19 |
| 2016 Marzo | 14 | 5 | 19 |
| 2016 Febrero | 13 | 7 | 20 |
| 2016 Enero | 13 | 10 | 23 |
| 2015 Diciembre | 9 | 2 | 11 |
| 2015 Noviembre | 19 | 1 | 20 |
| 2015 Octubre | 18 | 3 | 21 |
| 2015 Septiembre | 22 | 3 | 25 |
| 2015 Agosto | 22 | 4 | 26 |
| 2015 Julio | 14 | 7 | 21 |
| 2015 Junio | 4 | 4 | 8 |
| 2015 Mayo | 8 | 5 | 13 |
| 2015 Abril | 8 | 8 | 16 |
| 2015 Marzo | 30 | 5 | 35 |
| 2015 Febrero | 25 | 7 | 32 |
| 2015 Enero | 32 | 5 | 37 |
| 2014 Diciembre | 34 | 3 | 37 |
| 2014 Noviembre | 36 | 4 | 40 |
| 2014 Octubre | 33 | 3 | 36 |
| 2014 Septiembre | 22 | 4 | 26 |
| 2014 Agosto | 34 | 5 | 39 |
| 2014 Julio | 35 | 1 | 36 |
| 2014 Junio | 29 | 3 | 32 |
| 2014 Mayo | 27 | 6 | 33 |
| 2014 Abril | 25 | 4 | 29 |
| 2014 Marzo | 28 | 2 | 30 |
| 2014 Febrero | 28 | 3 | 31 |
| 2014 Enero | 21 | 2 | 23 |
| 2013 Diciembre | 22 | 4 | 26 |
| 2013 Noviembre | 18 | 2 | 20 |
| 2013 Octubre | 14 | 3 | 17 |
| 2013 Septiembre | 14 | 4 | 18 |
| 2013 Agosto | 33 | 4 | 37 |
| 2013 Julio | 18 | 1 | 19 |
| 2001 Diciembre | 449 | 0 | 449 |
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